Trait: sleep duration

Experimental Factor Ontology (EFO) Information
Identifier EFO_0005271
Description duration of sleep, measured either via a self-reporting questionnaire, interview or through obversation in a sleep lab
Trait category
Other measurement

Associated Polygenic Score(s)

Filter PGS by Participant Ancestry
Individuals included in:
G - Source of Variant Associations (GWAS)
D - Score Development/Training
E - PGS Evaluation
List of ancestries includes:
Display options:
Ancestry legend
Multi-ancestry (including European)
Multi-ancestry (excluding European)
African
East Asian
South Asian
Additional Asian Ancestries
European
Greater Middle Eastern
Hispanic or Latin American
Additional Diverse Ancestries
Not Reported
Polygenic Score ID & Name PGS Publication ID (PGP) Reported Trait Mapped Trait(s) (Ontology) Number of Variants Ancestry distribution
GWAS
Dev
Eval
Scoring File (FTP Link)
PGS001150
(GBE_INI1160)
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Sleep duration sleep duration 4,106
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001150/ScoringFiles/PGS001150.txt.gz
PGS001978
(portability-PLR_log_sleep)
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Sleep duration sleep duration 40,037
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001978/ScoringFiles/PGS001978.txt.gz
PGS002196
(portability-ldpred2_log_sleep)
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Sleep duration sleep duration 927,619
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002196/ScoringFiles/PGS002196.txt.gz
PGS003480
(LDPred2_SleepDuration)
PGP000456 |
Zhang Y et al. EBioMedicine (2022)
Sleep duration sleep duration 850,154
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003480/ScoringFiles/PGS003480.txt.gz
PGS003764
(PRS78_sleep duration)
PGP000487 |
Scammell BH et al. Hum Mol Genet (2023)
Sleep duration sleep duration 78
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003764/ScoringFiles/PGS003764.txt.gz

Performance Metrics

Disclaimer: The performance metrics are displayed as reported by the source studies. It is important to note that metrics are not necessarily comparable with each other. For example, metrics depend on the sample characteristics (described by the PGS Catalog Sample Set [PSS] ID), phenotyping, and statistical modelling. Please refer to the source publication for additional guidance on performance.

PGS Performance
Metric ID (PPM)
Evaluated Score PGS Sample Set ID
(PSS)
Performance Source Trait PGS Effect Sizes
(per SD change)
Classification Metrics Other Metrics Covariates Included in the Model PGS Performance:
Other Relevant Information
PPM008477 PGS001150
(GBE_INI1160)
PSS004796|
African Ancestry|
6,246 individuals
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Reported Trait: Sleep duration : 0.01014 [0.0053, 0.01499]
Incremental R2 (full-covars): 0.00154
PGS R2 (no covariates): 0.00168 [-0.00031, 0.00366]
age, sex, UKB array type, Genotype PCs
PPM008478 PGS001150
(GBE_INI1160)
PSS004797|
East Asian Ancestry|
1,652 individuals
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Reported Trait: Sleep duration : 0.04058 [0.02227, 0.0589]
Incremental R2 (full-covars): 0.00193
PGS R2 (no covariates): 0.00695 [-0.00089, 0.0148]
age, sex, UKB array type, Genotype PCs
PPM008479 PGS001150
(GBE_INI1160)
PSS004798|
European Ancestry|
24,750 individuals
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Reported Trait: Sleep duration : 0.01244 [0.00971, 0.01518]
Incremental R2 (full-covars): 0.00809
PGS R2 (no covariates): 0.00875 [0.00645, 0.01105]
age, sex, UKB array type, Genotype PCs
PPM008480 PGS001150
(GBE_INI1160)
PSS004799|
South Asian Ancestry|
7,598 individuals
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Reported Trait: Sleep duration : 0.008 [0.00407, 0.01193]
Incremental R2 (full-covars): 0.00387
PGS R2 (no covariates): 0.00403 [0.00123, 0.00683]
age, sex, UKB array type, Genotype PCs
PPM008481 PGS001150
(GBE_INI1160)
PSS004800|
European Ancestry|
67,069 individuals
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Reported Trait: Sleep duration : 0.01307 [0.01137, 0.01477]
Incremental R2 (full-covars): 0.00777
PGS R2 (no covariates): 0.00798 [0.00664, 0.00932]
age, sex, UKB array type, Genotype PCs
PPM010699 PGS001978
(portability-PLR_log_sleep)
PSS009466|
European Ancestry|
19,860 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Sleep duration Partial Correlation (partial-r): 0.1275 [0.1138, 0.1412] sex, age, birth date, deprivation index, 16 PCs
PPM010700 PGS001978
(portability-PLR_log_sleep)
PSS009240|
European Ancestry|
4,085 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Sleep duration Partial Correlation (partial-r): 0.1396 [0.1093, 0.1696] sex, age, birth date, deprivation index, 16 PCs
PPM010701 PGS001978
(portability-PLR_log_sleep)
PSS008794|
European Ancestry|
6,577 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Sleep duration Partial Correlation (partial-r): 0.1414 [0.1176, 0.165] sex, age, birth date, deprivation index, 16 PCs
PPM010702 PGS001978
(portability-PLR_log_sleep)
PSS008568|
Greater Middle Eastern Ancestry|
1,136 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Sleep duration Partial Correlation (partial-r): 0.099 [0.0405, 0.1567] sex, age, birth date, deprivation index, 16 PCs
PPM010703 PGS001978
(portability-PLR_log_sleep)
PSS008346|
South Asian Ancestry|
6,129 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Sleep duration Partial Correlation (partial-r): 0.0715 [0.0465, 0.0964] sex, age, birth date, deprivation index, 16 PCs
PPM010704 PGS001978
(portability-PLR_log_sleep)
PSS008123|
East Asian Ancestry|
1,773 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Sleep duration Partial Correlation (partial-r): 0.0557 [0.0089, 0.1022] sex, age, birth date, deprivation index, 16 PCs
PPM010705 PGS001978
(portability-PLR_log_sleep)
PSS007910|
African Ancestry|
2,358 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Sleep duration Partial Correlation (partial-r): 0.0669 [0.0264, 0.1071] sex, age, birth date, deprivation index, 16 PCs
PPM010706 PGS001978
(portability-PLR_log_sleep)
PSS009014|
African Ancestry|
3,721 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Sleep duration Partial Correlation (partial-r): 0.0234 [-0.0089, 0.0555] sex, age, birth date, deprivation index, 16 PCs
PPM012415 PGS002196
(portability-ldpred2_log_sleep)
PSS009466|
European Ancestry|
19,860 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Sleep duration Partial Correlation (partial-r): 0.1451 [0.1315, 0.1587] sex, age, birth date, deprivation index, 16 PCs
PPM012416 PGS002196
(portability-ldpred2_log_sleep)
PSS009240|
European Ancestry|
4,085 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Sleep duration Partial Correlation (partial-r): 0.1583 [0.1282, 0.1881] sex, age, birth date, deprivation index, 16 PCs
PPM012417 PGS002196
(portability-ldpred2_log_sleep)
PSS008794|
European Ancestry|
6,577 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Sleep duration Partial Correlation (partial-r): 0.1459 [0.1221, 0.1695] sex, age, birth date, deprivation index, 16 PCs
PPM012418 PGS002196
(portability-ldpred2_log_sleep)
PSS008568|
Greater Middle Eastern Ancestry|
1,136 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Sleep duration Partial Correlation (partial-r): 0.1258 [0.0676, 0.1831] sex, age, birth date, deprivation index, 16 PCs
PPM012419 PGS002196
(portability-ldpred2_log_sleep)
PSS008346|
South Asian Ancestry|
6,129 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Sleep duration Partial Correlation (partial-r): 0.0788 [0.0539, 0.1037] sex, age, birth date, deprivation index, 16 PCs
PPM012420 PGS002196
(portability-ldpred2_log_sleep)
PSS008123|
East Asian Ancestry|
1,773 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Sleep duration Partial Correlation (partial-r): 0.0978 [0.0512, 0.1439] sex, age, birth date, deprivation index, 16 PCs
PPM012421 PGS002196
(portability-ldpred2_log_sleep)
PSS007910|
African Ancestry|
2,358 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Sleep duration Partial Correlation (partial-r): 0.0851 [0.0447, 0.1252] sex, age, birth date, deprivation index, 16 PCs
PPM012422 PGS002196
(portability-ldpred2_log_sleep)
PSS009014|
African Ancestry|
3,721 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Sleep duration Partial Correlation (partial-r): 0.0331 sex, age, birth date, deprivation index, 16 PCs
PPM017289 PGS003480
(LDPred2_SleepDuration)
PSS010185|
Hispanic or Latin American Ancestry|
1,115 individuals
PGP000456 |
Zhang Y et al. EBioMedicine (2022)
Reported Trait: Respiratory event index β: -0.001 (0.01) Age, sex, center, 5 genetic PCs, Hispanic/Latino background, BMI
PPM017312 PGS003480
(LDPred2_SleepDuration)
PSS010185|
Hispanic or Latin American Ancestry|
1,115 individuals
PGP000456 |
Zhang Y et al. EBioMedicine (2022)
Reported Trait: Obstructive sleep apnea β: 0.008 (0.024) Age, sex, center, 5 genetic PCs, Hispanic/Latino background, BMI
PPM018565 PGS003764
(PRS78_sleep duration)
PSS011028|
East Asian Ancestry|
13,618 individuals
PGP000487 |
Scammell BH et al. Hum Mol Genet (2023)
Reported Trait: sleep duration β: 0.38 [0.22, 0.54] beta calculated as min/allele
PPM018566 PGS003764
(PRS78_sleep duration)
PSS011027|
African Ancestry|
7,288 individuals
PGP000487 |
Scammell BH et al. Hum Mol Genet (2023)
Reported Trait: sleep duration β: 0.62 [0.41, 0.83] beta calculated as min/allele
PPM018567 PGS003764
(PRS78_sleep duration)
PSS011029|
South Asian Ancestry|
7,485 individuals
PGP000487 |
Scammell BH et al. Hum Mol Genet (2023)
Reported Trait: sleep duration β: 0.39 [0.04, 0.74] beta calculated as min/allele

Evaluated Samples

PGS Sample Set ID
(PSS)
Phenotype Definitions and Methods Participant Follow-up Time Sample Numbers Age of Study Participants Sample Ancestry Additional Ancestry Description Cohort(s) Additional Sample/Cohort Information
PSS004796 6,246 individuals African unspecified UKB
PSS004797 1,652 individuals East Asian UKB
PSS004798 24,750 individuals European non-white British ancestry UKB
PSS004799 7,598 individuals South Asian UKB
PSS004800 67,069 individuals European white British ancestry UKB Testing cohort (heldout set)
PSS007910 2,358 individuals African American or Afro-Caribbean Carribean UKB
PSS011027 7,288 individuals,
42.1 % Male samples
Mean = 51.82 years
Sd = 8.06 years
African unspecified UKB
PSS011028 13,618 individuals,
45.3 % Male samples
Mean = 54.6 years
Sd = 9.4 years
East Asian J-MICC
PSS011029 7,485 individuals,
53.9 % Male samples
Mean = 53.39 years
Sd = 8.46 years
South Asian UKB
PSS009014 3,721 individuals African unspecified Nigeria (West Africa) UKB
PSS008123 1,773 individuals East Asian China (East Asia) UKB
PSS009240 4,085 individuals European Poland (NE Europe) UKB
PSS008568 1,136 individuals Greater Middle Eastern (Middle Eastern, North African or Persian) Iran (Middle East) UKB
PSS009466 19,860 individuals European UK (+ Ireland) UKB
PSS008794 6,577 individuals European Italy (South Europe) UKB
PSS008346 6,129 individuals South Asian India (South Asia) UKB
PSS010185 1,115 individuals,
41.1 % Male samples
Mean = 46.18 years Hispanic or Latin American HCHS, SOL