Trait: dentate gyrus volume measurement

Experimental Factor Ontology (EFO) Information
Identifier EFO_0010083
Description Quantification of the volume of the dentate gyrus.
Trait category
Other measurement
Mapped terms 2 mapped terms
  • PMID:31155012
  • Wikipedia:Dentate_gyrus

Associated Polygenic Score(s)

Filter PGS by Participant Ancestry
Individuals included in:
G - Source of Variant Associations (GWAS)
D - Score Development/Training
E - PGS Evaluation
List of ancestries includes:
Display options:
Ancestry legend
Multi-ancestry (including European)
Multi-ancestry (excluding European)
African
East Asian
South Asian
Additional Asian Ancestries
European
Greater Middle Eastern
Hispanic or Latin American
Additional Diverse Ancestries
Not Reported
Polygenic Score ID & Name PGS Publication ID (PGP) Reported Trait Mapped Trait(s) (Ontology) Number of Variants Ancestry distribution
GWAS
Dev
Eval
 Scoring File (FTP Link)
PGS003591
(L_GC-ML-DG_head_trans_ancestry_meta_analysis)
 PGP000464 |
Liu N et al. Nat Genet (2023)
 Left granule cell and molecular layer of the dentate gyrus head volume dentate gyrus volume measurement 16,477
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003591/ScoringFiles/PGS003591.txt.gz
PGS003592
(L_GC-ML-DG_body_trans_ancestry_meta_analysis)
 PGP000464 |
Liu N et al. Nat Genet (2023)
 Left granule cell and molecular layer of the dentate gyrus body volume dentate gyrus volume measurement 527
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003592/ScoringFiles/PGS003592.txt.gz
PGS003593
(R_GC-ML-DG_head_trans_ancestry_meta_analysis)
 PGP000464 |
Liu N et al. Nat Genet (2023)
 Right granule cell and molecular layer of the dentate gyrus head volume dentate gyrus volume measurement 15,738
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003593/ScoringFiles/PGS003593.txt.gz
PGS003594
(R_GC-ML-DG_body_trans_ancestry_meta_analysis)
 PGP000464 |
Liu N et al. Nat Genet (2023)
 Right granule cell and molecular layer of the dentate gyrus body volume dentate gyrus volume measurement 12
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003594/ScoringFiles/PGS003594.txt.gz
PGS003595
(L_GC-ML-DG_head_UKBB_EUR_GWAS)
 PGP000464 |
Liu N et al. Nat Genet (2023)
 Left granule cell and molecular layer of the dentate gyrus head volume dentate gyrus volume measurement 4,079
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003595/ScoringFiles/PGS003595.txt.gz
PGS003596
(L_GC-ML-DG_body_UKBB_EUR_GWAS)
 PGP000464 |
Liu N et al. Nat Genet (2023)
 Left granule cell and molecular layer of the dentate gyrus body volume dentate gyrus volume measurement 346
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003596/ScoringFiles/PGS003596.txt.gz
PGS003597
(R_GC-ML-DG_head_UKBB_EUR_GWAS)
 PGP000464 |
Liu N et al. Nat Genet (2023)
 Right granule cell and molecular layer of the dentate gyrus head volume dentate gyrus volume measurement 283
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003597/ScoringFiles/PGS003597.txt.gz
PGS003598
(R_GC-ML-DG_body_UKBB_EUR_GWAS)
 PGP000464 |
Liu N et al. Nat Genet (2023)
 Right granule cell and molecular layer of the dentate gyrus body volume dentate gyrus volume measurement 3,904
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003598/ScoringFiles/PGS003598.txt.gz
PGS003599
(L_GC-ML-DG_head_CHIMGEN_EAS_GWAS)
 PGP000464 |
Liu N et al. Nat Genet (2023)
 Left granule cell and molecular layer of the dentate gyrus head volume dentate gyrus volume measurement 1,931
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003599/ScoringFiles/PGS003599.txt.gz
PGS003600
(L_GC-ML-DG_body_CHIMGEN_EAS_GWAS)
 PGP000464 |
Liu N et al. Nat Genet (2023)
 Left granule cell and molecular layer of the dentate gyrus body volume dentate gyrus volume measurement 12,211
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003600/ScoringFiles/PGS003600.txt.gz
PGS003601
(R_GC-ML-DG_head_CHIMGEN_EAS_GWAS)
 PGP000464 |
Liu N et al. Nat Genet (2023)
 Right granule cell and molecular layer of the dentate gyrus head volume dentate gyrus volume measurement 48,751
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003601/ScoringFiles/PGS003601.txt.gz
PGS003602
(R_GC-ML-DG_body_CHIMGEN_EAS_GWAS)
 PGP000464 |
Liu N et al. Nat Genet (2023)
 Right granule cell and molecular layer of the dentate gyrus body volume dentate gyrus volume measurement 10,104
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003602/ScoringFiles/PGS003602.txt.gz

Performance Metrics

Disclaimer: The performance metrics are displayed as reported by the source studies. It is important to note that metrics are not necessarily comparable with each other. For example, metrics depend on the sample characteristics (described by the PGS Catalog Sample Set [PSS] ID), phenotyping, and statistical modelling. Please refer to the source publication for additional guidance on performance.

PGS Performance
Metric ID (PPM) 		Evaluated Score PGS Sample Set ID
(PSS) 		Performance Source Trait PGS Effect Sizes
(per SD change) 		Classification Metrics Other Metrics Covariates Included in the Model PGS Performance:
Other Relevant Information
PPM018298 PGS003591
(L_GC-ML-DG_head_trans_ancestry_meta_analysis)
 PSS010958|
East Asian Ancestry|
1,999 individuals
 PGP000464 |
Liu N et al. Nat Genet (2023)
 Reported Trait: Left granule cell and molecular layer of the dentate gyrus head volume — — R²: 0.01445 sex, age, age2, age × sex, total intracranial volume, and top six genetic principal components —
PPM018300 PGS003592
(L_GC-ML-DG_body_trans_ancestry_meta_analysis)
 PSS010958|
East Asian Ancestry|
1,999 individuals
 PGP000464 |
Liu N et al. Nat Genet (2023)
 Reported Trait: Left granule cell and molecular layer of the dentate gyrus body volume — — R²: 0.01849 sex, age, age2, age × sex, total intracranial volume, and top six genetic principal components —
PPM018319 PGS003593
(R_GC-ML-DG_head_trans_ancestry_meta_analysis)
 PSS010958|
East Asian Ancestry|
1,999 individuals
 PGP000464 |
Liu N et al. Nat Genet (2023)
 Reported Trait: Right granule cell and molecular layer of the dentate gyrus head volume — — R²: 0.01386 sex, age, age2, age × sex, total intracranial volume, and top six genetic principal components —
PPM018321 PGS003594
(R_GC-ML-DG_body_trans_ancestry_meta_analysis)
 PSS010958|
East Asian Ancestry|
1,999 individuals
 PGP000464 |
Liu N et al. Nat Genet (2023)
 Reported Trait: Right granule cell and molecular layer of the dentate gyrus body volume — — R²: 0.01387 sex, age, age2, age × sex, total intracranial volume, and top six genetic principal components —
PPM018342 PGS003595
(L_GC-ML-DG_head_UKBB_EUR_GWAS)
 PSS010958|
East Asian Ancestry|
1,999 individuals
 PGP000464 |
Liu N et al. Nat Genet (2023)
 Reported Trait: Left granule cell and molecular layer of the dentate gyrus head volume — — R²: 0.00594 sex, age, age2, age × sex, total intracranial volume, and top six genetic principal components —
PPM018344 PGS003596
(L_GC-ML-DG_body_UKBB_EUR_GWAS)
 PSS010958|
East Asian Ancestry|
1,999 individuals
 PGP000464 |
Liu N et al. Nat Genet (2023)
 Reported Trait: Left granule cell and molecular layer of the dentate gyrus body volume — — R²: 0.00742 sex, age, age2, age × sex, total intracranial volume, and top six genetic principal components —
PPM018363 PGS003597
(R_GC-ML-DG_head_UKBB_EUR_GWAS)
 PSS010958|
East Asian Ancestry|
1,999 individuals
 PGP000464 |
Liu N et al. Nat Genet (2023)
 Reported Trait: Right granule cell and molecular layer of the dentate gyrus head volume — — R²: 0.00692 sex, age, age2, age × sex, total intracranial volume, and top six genetic principal components —
PPM018365 PGS003598
(R_GC-ML-DG_body_UKBB_EUR_GWAS)
 PSS010958|
East Asian Ancestry|
1,999 individuals
 PGP000464 |
Liu N et al. Nat Genet (2023)
 Reported Trait: Right granule cell and molecular layer of the dentate gyrus body volume — — R²: 0.00706 sex, age, age2, age × sex, total intracranial volume, and top six genetic principal components —
PPM018386 PGS003599
(L_GC-ML-DG_head_CHIMGEN_EAS_GWAS)
 PSS010958|
East Asian Ancestry|
1,999 individuals
 PGP000464 |
Liu N et al. Nat Genet (2023)
 Reported Trait: Left granule cell and molecular layer of the dentate gyrus head volume — — R²: 0.00308 sex, age, age2, age × sex, total intracranial volume, and top six genetic principal components —
PPM018388 PGS003600
(L_GC-ML-DG_body_CHIMGEN_EAS_GWAS)
 PSS010958|
East Asian Ancestry|
1,999 individuals
 PGP000464 |
Liu N et al. Nat Genet (2023)
 Reported Trait: Left granule cell and molecular layer of the dentate gyrus body volume — — R²: 0.00637 sex, age, age2, age × sex, total intracranial volume, and top six genetic principal components —
PPM018407 PGS003601
(R_GC-ML-DG_head_CHIMGEN_EAS_GWAS)
 PSS010958|
East Asian Ancestry|
1,999 individuals
 PGP000464 |
Liu N et al. Nat Genet (2023)
 Reported Trait: Right granule cell and molecular layer of the dentate gyrus head volume — — R²: 0.00501 sex, age, age2, age × sex, total intracranial volume, and top six genetic principal components —
PPM018409 PGS003602
(R_GC-ML-DG_body_CHIMGEN_EAS_GWAS)
 PSS010958|
East Asian Ancestry|
1,999 individuals
 PGP000464 |
Liu N et al. Nat Genet (2023)
 Reported Trait: Right granule cell and molecular layer of the dentate gyrus body volume — — R²: 0.00956 sex, age, age2, age × sex, total intracranial volume, and top six genetic principal components —

Evaluated Samples

PGS Sample Set ID
(PSS) 		Phenotype Definitions and Methods Participant Follow-up Time Sample Numbers Age of Study Participants Sample Ancestry Additional Ancestry Description Cohort(s) Additional Sample/Cohort Information
PSS010958 — — 1,999 individuals — East Asian — CHIMGEN —