| PGS Publication/Study ID (PGP) | PGS Developed | PGS Evaluated | First Author | Title | Journal Name | Publication Date | Digital object identifier (doi) | PubMed ID (PMID) |
|---|---|---|---|---|---|---|---|---|
| PGP000095 | 2 | 2 | Meisner A | Combined Utility of 25 Disease and Risk Factor Polygenic Risk Scores for Stratifying Risk of All-Cause Mortality. | Am J Hum Genet | 26/07/2020 | 10.1016/j.ajhg.2020.07.002 | 32758451 |
| PGP000055 | 3 | 3 | Fritsche LG | Exploring various polygenic risk scores for skin cancer in the phenomes of the Michigan genomics initiative and the UK Biobank with a visual catalog: PRSWeb. | PLoS Genet | 13/06/2019 | 10.1371/journal.pgen.1008202 | 31194742 |
| PGP000028 | 1 | 1 | Abraham G | Accurate and robust genomic prediction of celiac disease using statistical learning. | PLoS Genet | 13/02/2014 | 10.1371/journal.pgen.1004137 | 24550740 |
| PGP000029 | 2 | 3 | Abraham G | Genomic prediction of celiac disease targeting HLA-positive individuals. | Genome Med | 16/07/2015 | 10.1186/s13073-015-0196-5 | 26244058 |
| PGP000068 | 8 | 8 | Cai N | Minimal phenotyping yields genome-wide association signals of low specificity for major depression. | Nat Genet | 30/03/2020 | 10.1038/s41588-020-0594-5 | 32231276 |
| PGP000072 | 1 | 1 | Smith T | The added value of genetic information in colorectal cancer risk prediction models: development and evaluation in the UK Biobank prospective cohort study. | Br J Cancer | 16/10/2018 | 10.1038/s41416-018-0282-8 | 30323197 |
| PGP000004 | 1 | 2 | Tada H | Risk prediction by genetic risk scores for coronary heart disease is independent of self-reported family history. | Eur Heart J | 20/09/2015 | 10.1093/eurheartj/ehv462 | 26392438 |
| PGP000005 | 1 | 2 | Abraham G | Genomic prediction of coronary heart disease. | Eur Heart J | 21/09/2016 | 10.1093/eurheartj/ehw450 | 27655226 |
| PGP000069 | 1 | 1 | Hsu L | A model to determine colorectal cancer risk using common genetic susceptibility loci. | Gastroenterology | 13/02/2015 | 10.1053/j.gastro.2015.02.010 | 25683114 |
| PGP000070 | 1 | 1 | Ibáñez-Sanz G | Risk Model for Colorectal Cancer in Spanish Population Using Environmental and Genetic Factors: Results from the MCC-Spain study. | Sci Rep | 24/02/2017 | 10.1038/srep43263 | 28233817 |
| PGP000071 | 1 | 1 | Jeon J | Determining Risk of Colorectal Cancer and Starting Age of Screening Based on Lifestyle, Environmental, and Genetic Factors. | Gastroenterology | 17/02/2018 | 10.1053/j.gastro.2018.02.021 | 29458155 |
| PGP000088 | 5 | 7 | Zhang H | Genome-wide association study identifies 32 novel breast cancer susceptibility loci from overall and subtype-specific analyses. | Nat Genet | 18/05/2020 | 10.1038/s41588-020-0609-2 | 32424353 |
| PGP000073 | 1 | 1 | Weigl K | Genetic Risk Score Is Associated With Prevalence of Advanced Neoplasms in a Colorectal Cancer Screening Population. | Gastroenterology | 21/03/2018 | 10.1053/j.gastro.2018.03.030 | 29574091 |
| PGP000075 | 11 | 11 | Shi Z | Systematic evaluation of cancer-specific genetic risk score for 11 types of cancer in The Cancer Genome Atlas and Electronic Medical Records and Genomics cohorts. | Cancer Med | 09/04/2019 | 10.1002/cam4.2143 | 30968590 |
| PGP000058 | 0 | 1 | Huynh-Le M | Polygenic hazard score predicts aggressive and fatal prostate cancer in multi-ethnic populations | medRxivPre | 19/11/2019 | 10.1101/19012237 | — |
| PGP000030 | 1 | 1 | Klarin D | Genome-wide association analysis of venous thromboembolism identifies new risk loci and genetic overlap with arterial vascular disease. | Nat Genet | 01/11/2019 | 10.1038/s41588-019-0519-3 | 31676865 |
| PGP000031 | 1 | 1 | Pashayan N | Reducing overdiagnosis by polygenic risk-stratified screening: findings from the Finnish section of the ERSPC. | Br J Cancer | 20/08/2015 | 10.1038/bjc.2015.289 | 26291059 |
| PGP000032 | 0 | 1 | Pashayan N | Implications of polygenic risk-stratified screening for prostate cancer on overdiagnosis. | Genet Med | 08/01/2015 | 10.1038/gim.2014.192 | 25569441 |
| PGP000033 | 4 | 7 | Kuchenbaecker KB | Evaluation of Polygenic Risk Scores for Breast and Ovarian Cancer Risk Prediction in BRCA1 and BRCA2 Mutation Carriers. | J Natl Cancer Inst | 01/07/2017 | 10.1093/jnci/djw302 | 28376175 |
| PGP000034 | 1 | 4 | Lecarpentier J | Prediction of Breast and Prostate Cancer Risks in Male BRCA1 and BRCA2 Mutation Carriers Using Polygenic Risk Scores. | J Clin Oncol | 27/04/2017 | 10.1200/JCO.2016.69.4935 | 28448241 |
| PGP000096 | 1 | 1 | Chami N | The role of polygenic susceptibility to obesity among carriers of pathogenic mutations in MC4R in the UK Biobank population. | PLoS Med | 21/07/2020 | 10.1371/journal.pmed.1003196 | 32692746 |
| PGP000098 | 1 | 1 | Grove J | Identification of common genetic risk variants for autism spectrum disorder. | Nat Genet | 25/02/2019 | 10.1038/s41588-019-0344-8 | 30804558 |
| PGP000103 | 1 | 1 | Maukonen M | Genetic Associations of Chronotype in the Finnish General Population. | J Biol Rhythms | 24/06/2020 | 10.1177/0748730420935328 | 32579418 |
| PGP000104 | 1 | 1 | Koyama S | Population-specific and trans-ancestry genome-wide analyses identify distinct and shared genetic risk loci for coronary artery disease. | Nat Genet | 05/10/2020 | 10.1038/s41588-020-0705-3 | 33020668 |
| PGP000105 | 1 | 1 | Kloosterman M | Genetic risk and atrial fibrillation in patients with heart failure. | Eur J Heart Fail | 09/01/2020 | 10.1002/ejhf.1735 | 31919934 |
| PGP000117 | 2 | 5 | Barnes DR | Polygenic risk scores and breast and epithelial ovarian cancer risks for carriers of BRCA1 and BRCA2 pathogenic variants. | Genet Med | 15/07/2020 | 10.1038/s41436-020-0862-x | 32665703 |
| PGP000035 | 1 | 1 | Wen W | Prediction of breast cancer risk based on common genetic variants in women of East Asian ancestry. | Breast Cancer Res | 08/12/2016 | 10.1186/s13058-016-0786-1 | 27931260 |
| PGP000036 | 1 | 1 | Zhang X | Addition of a polygenic risk score, mammographic density, and endogenous hormones to existing breast cancer risk prediction models: A nested case-control study. | PLoS Med | 04/09/2018 | 10.1371/journal.pmed.1002644 | 30180161 |
| PGP000037 | 1 | 1 | Lakeman IMM | Addition of a 161-SNP polygenic risk score to family history-based risk prediction: impact on clinical management in non-BRCA1/2 breast cancer families. | J Med Genet | 11/06/2019 | 10.1136/jmedgenet-2019-106072 | 31186341 |
| PGP000079 | 1 | 1 | Kathiresan S | Polymorphisms associated with cholesterol and risk of cardiovascular events. | N Engl J Med | 01/03/2008 | 10.1056/nejmoa0706728 | 18354102 |
| PGS000080 | 1 | 1 | Coleman JRI | Genome-wide gene-environment analyses of major depressive disorder and reported lifetime traumatic experiences in UK Biobank. | Mol Psychiatry | 23/01/2020 | 10.1038/s41380-019-0546-6 | 31969693 |
| PGP000009 | 1 | 1 | Paquette M | Polygenic risk score predicts prevalence of cardiovascular disease in patients with familial hypercholesterolemia. | J Clin Lipidol | 06/04/2017 | 10.1016/j.jacl.2017.03.019 | 28456682 |
| PGP000010 | 1 | 1 | Läll K | Personalized risk prediction for type 2 diabetes: the potential of genetic risk scores. | Genet Med | 11/08/2016 | 10.1038/gim.2016.103 | 27513194 |
| PGP000112 | 4 | 4 | Ho WK | European polygenic risk score for prediction of breast cancer shows similar performance in Asian women. | Nat Commun | 31/07/2020 | 10.1038/s41467-020-17680-w | 32737321 |
| PGP000097 | 3 | 3 | Flynn E | Sex-specific genetic effects across biomarkers. | Eur J Hum Genet | 01/09/2020 | 10.1038/s41431-020-00712-w | 32873964 |
| PGP000011 | 1 | 1 | Oram RA | A Type 1 Diabetes Genetic Risk Score Can Aid Discrimination Between Type 1 and Type 2 Diabetes in Young Adults. | Diabetes Care | 17/11/2015 | 10.2337/dc15-1111 | 26577414 |
| PGP000041 | 1 | 1 | Paul KC | Association of Polygenic Risk Score With Cognitive Decline and Motor Progression in Parkinson Disease. | JAMA Neurol | 01/03/2018 | 10.1001/jamaneurol.2017.4206 | 29340614 |
| PGP000076 | 0 | 1 | Khera AV | Genetic Risk, Adherence to a Healthy Lifestyle, and Coronary Disease. | N Engl J Med | 13/11/2016 | 10.1056/NEJMoa1605086 | 27959714 |
| PGP000077 | 0 | 1 | Timmerman N | Family history and polygenic risk of cardiovascular disease: independent factors associated with secondary cardiovascular manifestations in patients undergoing carotid endarterectomy | medRxivPre | 18/09/2019 | 10.1101/19006718 | — |
| PGP000018 | 2 | 2 | Shieh Y | Breast cancer risk prediction using a clinical risk model and polygenic risk score. | Breast Cancer Res Treat | 26/08/2016 | 10.1007/s10549-016-3953-2 | 27565998 |
| PGP000106 | 1 | 1 | Law MH | Multiplex melanoma families are enriched for polygenic risk. | Hum Mol Genet | 01/10/2020 | 10.1093/hmg/ddaa156 | 32716505 |
| PGP000099 | 1 | 1 | Reid S | High genetic risk score is associated with early disease onset, damage accrual and decreased survival in systemic lupus erythematosus. | Ann Rheum Dis | 11/12/2019 | 10.1136/annrheumdis-2019-216227 | 31826855 |
| PGP000108 | 0 | 1 | Hindy G | Genome-Wide Polygenic Score, Clinical Risk Factors, and Long-Term Trajectories of Coronary Artery Disease. | Arterioscler Thromb Vasc Biol | 22/09/2020 | 10.1161/atvbaha.120.314856 | 32957805 |
| PGP000081 | 6 | 6 | Knevel R | Using genetics to prioritize diagnoses for rheumatology outpatients with inflammatory arthritis. | Sci Transl Med | 01/05/2020 | 10.1126/scitranslmed.aay1548 | 32461333 |
| PGP000001 | 3 | 3 | Mavaddat N | Prediction of breast cancer risk based on profiling with common genetic variants. | J Natl Cancer Inst | 08/04/2015 | 10.1093/jnci/djv036 | 25855707 |
| PGP000002 | 6 | 9 | Mavaddat N | Polygenic Risk Scores for Prediction of Breast Cancer and Breast Cancer Subtypes. | Am J Hum Genet | 13/12/2018 | 10.1016/j.ajhg.2018.11.002 | 30554720 |
| PGP000078 | 29 | 27 | Vuckovic D | The Polygenic and Monogenic Basis of Blood Traits and Diseases. | Cell | 01/09/2020 | 10.1016/j.cell.2020.08.008 | 32888494 |
| PGP000074 | 1 | 1 | Xin J | Evaluating the effect of multiple genetic risk score models on colorectal cancer risk prediction. | Gene | 14/06/2018 | 10.1016/j.gene.2018.06.035 | 29908285 |
| PGP000016 | 1 | 1 | Desikan RS | Genetic assessment of age-associated Alzheimer disease risk: Development and validation of a polygenic hazard score. | PLoS Med | 21/03/2017 | 10.1371/journal.pmed.1002258 | 28323831 |
| PGP000017 | 1 | 1 | Khera AV | Polygenic Prediction of Weight and Obesity Trajectories from Birth to Adulthood. | Cell | 01/04/2019 | 10.1016/j.cell.2019.03.028 | 31002795 |
| PGP000019 | 1 | 1 | Schumacher FR | Association analyses of more than 140,000 men identify 63 new prostate cancer susceptibility loci. | Nat Genet | 11/06/2018 | 10.1038/s41588-018-0142-8 | 29892016 |
| PGP000022 | 1 | 1 | Weng LC | Genetic Predisposition, Clinical Risk Factor Burden, and Lifetime Risk of Atrial Fibrillation. | Circulation | 12/11/2017 | 10.1161/CIRCULATIONAHA.117.031431 | 29129827 |
| PGP000100 | 5 | 5 | Mars N | Polygenic and clinical risk scores and their impact on age at onset and prediction of cardiometabolic diseases and common cancers. | Nat Med | 07/04/2020 | 10.1038/s41591-020-0800-0 | 32273609 |
| PGP000109 | 0 | 4 | Kramer I | Breast Cancer Polygenic Risk Score and Contralateral Breast Cancer Risk. | Am J Hum Genet | 05/10/2020 | 10.1016/j.ajhg.2020.09.001 | 33022221 |
| PGP000091 | 0 | 1 | Ferrat LA | A combined risk score enhances prediction of type 1 diabetes among susceptible children. | Nat Med | 07/08/2020 | 10.1038/s41591-020-0930-4 | 32770166 |
| PGP000090 | 1 | 2 | Wang M | Validation of a Genome-Wide Polygenic Score for Coronary Artery Disease in South Asians. | J Am Coll Cardiol | 01/08/2020 | 10.1016/j.jacc.2020.06.024 | 32762905 |
| PGP000107 | 1 | 1 | Trinder M | Polygenic Contribution to Low-Density Lipoprotein Cholesterol Levels and Cardiovascular Risk in Monogenic Familial Hypercholesterolemia. | Circ Genom Precis Med | 13/08/2020 | 10.1161/circgen.120.002919 | 33079599 |
| PGP000082 | 1 | 1 | Tikkanen E | Genetic risk prediction and a 2-stage risk screening strategy for coronary heart disease. | Arterioscler Thromb Vasc Biol | 18/04/2013 | 10.1161/atvbaha.112.301120 | 23599444 |
| PGP000003 | 1 | 1 | Mega JL | Genetic risk, coronary heart disease events, and the clinical benefit of statin therapy: an analysis of primary and secondary prevention trials. | Lancet | 04/03/2015 | 10.1016/S0140-6736(14)61730-X | 25748612 |
| PGP000101 | 1 | 1 | Zhang Q | Risk prediction of late-onset Alzheimer's disease implies an oligogenic architecture. | Nat Commun | 23/09/2020 | 10.1038/s41467-020-18534-1 | 32968074 |
| PGP000092 | 19 | 19 | Xie T | Genetic Risk Scores for Complex Disease Traits in Youth. | Circ Genom Precis Med | 11/06/2020 | 10.1161/circgen.119.002775 | 32527150 |
| PGP000083 | 0 | 4 | Dikilitas O | Predictive Utility of Polygenic Risk Scores for Coronary Heart Disease in Three Major Racial and Ethnic Groups. | Am J Hum Genet | 01/05/2020 | 10.1016/j.ajhg.2020.04.002 | 32386537 |
| PGP000119 | 2 | 2 | Namjou B | GWAS and enrichment analyses of non-alcoholic fatty liver disease identify new trait-associated genes and pathways across eMERGE Network. | BMC Med | 17/07/2019 | 10.1186/s12916-019-1364-z | 31311600 |
| PGP000093 | 1 | 1 | Sharp SA | A single nucleotide polymorphism genetic risk score to aid diagnosis of coeliac disease: a pilot study in clinical care. | Aliment Pharmacol Ther | 13/08/2020 | 10.1111/apt.15826 | 32790217 |
| PGP000084 | 6 | 6 | Barr PB | Using polygenic scores for identifying individuals at increased risk of substance use disorders in clinical and population samples. | Transl Psychiatry | 18/06/2020 | 10.1038/s41398-020-00865-8 | 32555147 |
| PGP000110 | 1 | 1 | Bossini-Castillo L | Genomic Risk Score impact on susceptibility to systemic sclerosis. | Ann Rheum Dis | 01/10/2020 | 10.1136/annrheumdis-2020-218558 | 33004331 |
| PGP000111 | 2 | 2 | Smith MP | Evaluation of a Genetic Risk Score for Diagnosis of Psoriatic Arthritis. | J Psoriasis Psoriatic Arthritis | 04/03/2020 | 10.1177/2475530320910814 | 32462110 |
| PGP000118 | 302 | 302 | Fritsche LG | Cancer PRSweb: An Online Repository with Polygenic Risk Scores for Major Cancer Traits and Their Evaluation in Two Independent Biobanks. | Am J Hum Genet | 28/09/2020 | 10.1016/j.ajhg.2020.08.025 | 32991828 |
| PGP000020 | 3 | 3 | Vassy JL | Polygenic type 2 diabetes prediction at the limit of common variant detection. | Diabetes | 11/02/2014 | 10.2337/db13-1663 | 24520119 |
| PGP000021 | 1 | 1 | Song M | Longitudinal Analysis of Genetic Susceptibility and BMI Throughout Adult Life. | Diabetes | 06/12/2017 | 10.2337/db17-1156 | 29212779 |
| PGP000094 | 1 | 1 | Shieh Y | A Polygenic Risk Score for Breast Cancer in US Latinas and Latin American Women. | J Natl Cancer Inst | 01/06/2020 | 10.1093/jnci/djz174 | 31553449 |
| PGP000006 | 5 | 5 | Khera AV | Genome-wide polygenic scores for common diseases identify individuals with risk equivalent to monogenic mutations. | Nat Genet | 13/08/2018 | 10.1038/s41588-018-0183-z | 30104762 |
| PGP000120 | 1 | 1 | Forgetta V | Development of a polygenic risk score to improve screening for fracture risk: A genetic risk prediction study. | PLoS Med | 02/07/2020 | 10.1371/journal.pmed.1003152 | 32614825 |
| PGP000023 | 1 | 0 | Mahajan A | Fine-mapping type 2 diabetes loci to single-variant resolution using high-density imputation and islet-specific epigenome maps. | Nat Genet | 08/10/2018 | 10.1038/s41588-018-0241-6 | 30297969 |
| PGP000024 | 0 | 1 | Udler MS | Genetic Risk Scores for Diabetes Diagnosis and Precision Medicine. | Endocr Rev | 01/12/2019 | 10.1210/er.2019-00088 | 31322649 |
| PGP000025 | 1 | 1 | Belsky DW | Polygenic risk and the development and course of asthma: an analysis of data from a four-decade longitudinal study. | Lancet Respir Med | 28/06/2013 | 10.1016/S2213-2600(13)70101-2 | 24429243 |
| PGP000008 | 0 | 2 | Wünnemann F | Validation of Genome-Wide Polygenic Risk Scores for Coronary Artery Disease in French Canadians. | Circ Genom Precis Med | 11/06/2019 | 10.1161/CIRCGEN.119.002481 | 31184202 |
| PGP000026 | 1 | 1 | Rutten-Jacobs LC | Genetic risk, incident stroke, and the benefits of adhering to a healthy lifestyle: cohort study of 306 473 UK Biobank participants. | BMJ | 24/10/2018 | 10.1136/bmj.k4168 | 30355576 |
| PGP000027 | 1 | 2 | Abraham G | Genomic risk score offers predictive performance comparable to clinical risk factors for ischaemic stroke. | Nat Commun | 20/12/2019 | 10.1038/s41467-019-13848-1 | 31862893 |
| PGP000015 | 1 | 1 | Chouraki V | Evaluation of a Genetic Risk Score to Improve Risk Prediction for Alzheimer's Disease. | J Alzheimers Dis | 01/06/2016 | 10.3233/JAD-150749 | 27340842 |
| PGP000063 | 1 | 1 | Tin A | Target genes, variants, tissues and transcriptional pathways influencing human serum urate levels. | Nat Genet | 02/10/2019 | 10.1038/s41588-019-0504-x | 31578528 |
| PGP000064 | 6 | 6 | Wheeler E | Impact of common genetic determinants of Hemoglobin A1c on type 2 diabetes risk and diagnosis in ancestrally diverse populations: A transethnic genome-wide meta-analysis. | PLoS Med | 12/09/2017 | 10.1371/journal.pmed.1002383 | 28898252 |
| PGP000066 | 1 | 1 | Craig JE | Multitrait analysis of glaucoma identifies new risk loci and enables polygenic prediction of disease susceptibility and progression. | Nat Genet | 20/01/2020 | 10.1038/s41588-019-0556-y | 31959993 |
| PGP000038 | 0 | 1 | Patel KA | Type 1 Diabetes Genetic Risk Score: A Novel Tool to Discriminate Monogenic and Type 1 Diabetes. | Diabetes | 05/04/2016 | 10.2337/db15-1690 | 27207547 |
| PGP000039 | 2 | 2 | Tosto G | Polygenic risk scores in familial Alzheimer disease. | Neurology | 17/02/2017 | 10.1212/WNL.0000000000003734 | 28213371 |
| PGP000040 | 1 | 1 | Schmit SL | Novel Common Genetic Susceptibility Loci for Colorectal Cancer. | J Natl Cancer Inst | 01/02/2019 | 10.1093/jnci/djy099 | 29917119 |
| PGP000042 | 1 | 1 | Natarajan P | Polygenic Risk Score Identifies Subgroup With Higher Burden of Atherosclerosis and Greater Relative Benefit From Statin Therapy in the Primary Prevention Setting. | Circulation | 21/02/2017 | 10.1161/CIRCULATIONAHA.116.024436 | 28223407 |
| PGP000043 | 1 | 1 | Morieri ML | Genetic Tools for Coronary Risk Assessment in Type 2 Diabetes: A Cohort Study From the ACCORD Clinical Trial. | Diabetes Care | 27/09/2018 | 10.2337/dc18-0709 | 30262460 |
| PGP000007 | 1 | 3 | Inouye M | Genomic Risk Prediction of Coronary Artery Disease in 480,000 Adults: Implications for Primary Prevention. | J Am Coll Cardiol | 01/10/2018 | 10.1016/j.jacc.2018.07.079 | 30309464 |
| PGP000012 | 1 | 1 | Perry DJ | Application of a Genetic Risk Score to Racially Diverse Type 1 Diabetes Populations Demonstrates the Need for Diversity in Risk-Modeling. | Sci Rep | 14/03/2018 | 10.1038/s41598-018-22574-5 | 29540798 |
| PGP000013 | 1 | 2 | Onengut-Gumuscu S | Type 1 Diabetes Risk in African-Ancestry Participants and Utility of an Ancestry-Specific Genetic Risk Score. | Diabetes Care | 18/01/2019 | 10.2337/dc18-1727 | 30659077 |
| PGP000044 | 1 | 1 | Hajek C | Coronary Heart Disease Genetic Risk Score Predicts Cardiovascular Disease Risk in Men, Not Women. | Circ Genom Precis Med | 01/10/2018 | 10.1161/CIRCGEN.118.002324 | 30354305 |
| PGP000045 | 4 | 4 | Johnson L | An Examination of the Relationship between Lipid Levels and Associated Genetic Markers across Racial/Ethnic Populations in the Multi-Ethnic Study of Atherosclerosis. | PLoS One | 07/05/2015 | 10.1371/journal.pone.0126361 | 25951326 |
| PGP000046 | 3 | 3 | Kuchenbaecker K | The transferability of lipid loci across African, Asian and European cohorts. | Nat Commun | 24/09/2019 | 10.1038/s41467-019-12026-7 | 31551420 |
| PGP000047 | 1 | 1 | Seibert TM | Polygenic hazard score to guide screening for aggressive prostate cancer: development and validation in large scale cohorts. | BMJ | 10/01/2018 | 10.1136/bmj.j5757 | 29321194 |
| PGP000048 | 2 | 2 | Yang X | Evaluation of polygenic risk scores for ovarian cancer risk prediction in a prospective cohort study. | J Med Genet | 05/05/2018 | 10.1136/jmedgenet-2018-105313 | 29730597 |
| PGP000085 | 3 | 3 | Liyanarachchi S | Assessing thyroid cancer risk using polygenic risk scores. | Proc Natl Acad Sci U S A | 04/03/2020 | 10.1073/pnas.1919976117 | 32132206 |
| PGP000014 | 1 | 2 | Sharp SA | Development and Standardization of an Improved Type 1 Diabetes Genetic Risk Score for Use in Newborn Screening and Incident Diagnosis. | Diabetes Care | 01/02/2019 | 10.2337/dc18-1785 | 30655379 |
| PGP000062 | 1 | 1 | Qi Q | Genetics of Type 2 Diabetes in U.S. Hispanic/Latino Individuals: Results From the Hispanic Community Health Study/Study of Latinos (HCHS/SOL). | Diabetes | 02/03/2017 | 10.2337/db16-1150 | 28254843 |
| PGP000086 | 1 | 1 | Shrine N | New genetic signals for lung function highlight pathways and chronic obstructive pulmonary disease associations across multiple ancestries. | Nat Genet | 25/02/2019 | 10.1038/s41588-018-0321-7 | 30804560 |
| PGP000113 | 1 | 1 | Black MH | Validation of a prostate cancer polygenic risk score. | Prostate | 17/08/2020 | 10.1002/pros.24058 | 33258481 |
| PGP000049 | 1 | 1 | Dai J | Identification of risk loci and a polygenic risk score for lung cancer: a large-scale prospective cohort study in Chinese populations. | Lancet Respir Med | 17/07/2019 | 10.1016/S2213-2600(19)30144-4 | 31326317 |
| PGP000051 | 26 | 26 | Xu Y | Learning polygenic scores for human blood cell traits | bioRxivPre | 18/02/2020 | 10.1101/2020.02.17.952788 | — |
| PGP000114 | 1 | 1 | Pechlivanis S | Risk prediction for coronary heart disease by a genetic risk score - results from the Heinz Nixdorf Recall study. | BMC Med Genet | 10/09/2020 | 10.1186/s12881-020-01113-y | 32912153 |
| PGP000053 | 1 | 1 | Trinder M | Association of Monogenic vs Polygenic Hypercholesterolemia With Risk of Atherosclerotic Cardiovascular Disease. | JAMA Cardiol | 12/02/2020 | 10.1001/jamacardio.2019.5954 | 32049305 |
| PGP000054 | 2 | 2 | Elliott J | Predictive Accuracy of a Polygenic Risk Score-Enhanced Prediction Model vs a Clinical Risk Score for Coronary Artery Disease. | JAMA | 01/02/2020 | 10.1001/jama.2019.22241 | 32068818 |
| PGP000056 | 2 | 2 | Ho-Le TP | Prediction of Bone Mineral Density and Fragility Fracture by Genetic Profiling. | J Bone Miner Res | 26/10/2016 | 10.1002/jbmr.2998 | 27649491 |
| PGP000052 | 4 | 4 | Cánovas R | Genomic risk scores for juvenile idiopathic arthritis and its subtypes. | Ann Rheum Dis | 04/09/2020 | 10.1136/annrheumdis-2020-217421 | 32887683 |
| PGP000057 | 0 | 3 | Homburger JR | Low coverage whole genome sequencing enables accurate assessment of common variants and calculation of genome-wide polygenic scores. | Genome Med | 26/11/2019 | 10.1186/s13073-019-0682-2 | 31771638 |
| PGP000059 | 1 | 1 | Ibanez L | Parkinson disease polygenic risk score is associated with Parkinson disease status and age at onset but not with alpha-synuclein cerebrospinal fluid levels. | BMC Neurol | 15/11/2017 | 10.1186/s12883-017-0978-z | 29141588 |
| PGP000060 | 0 | 1 | Khera AV | Whole-Genome Sequencing to Characterize Monogenic and Polygenic Contributions in Patients Hospitalized With Early-Onset Myocardial Infarction. | Circulation | 01/03/2019 | 10.1161/circulationaha.118.035658 | 30586733 |
| PGP000115 | 1 | 1 | Fan BJ | Association of a Primary Open-Angle Glaucoma Genetic Risk Score With Earlier Age at Diagnosis. | JAMA Ophthalmol | 22/08/2019 | 10.1001/jamaophthalmol.2019.3109 | 31436842 |
| PGP000050 | 16 | 16 | Graff RE | Cross-cancer evaluation of polygenic risk scores for 16 cancer types in two large cohorts. | Nat Commun | 12/02/2021 | 10.1038/s41467-021-21288-z | 33579919 |
| PGP000061 | 1 | 1 | MacGregor S | Genome-wide association study of intraocular pressure uncovers new pathways to glaucoma. | Nat Genet | 27/07/2018 | 10.1038/s41588-018-0176-y | 30054594 |
| PGP000065 | 4 | 4 | Zheutlin AB | Penetrance and Pleiotropy of Polygenic Risk Scores for Schizophrenia in 106,160 Patients Across Four Health Care Systems. | Am J Psychiatry | 16/08/2019 | 10.1176/appi.ajp.2019.18091085 | 31416338 |
| PGP000087 | 1 | 1 | Pihlstrøm L | A cumulative genetic risk score predicts progression in Parkinson's disease. | Mov Disord | 08/02/2016 | 10.1002/mds.26505 | 26853697 |
| PGP000116 | 0 | 1 | Aragam KG | Limitations of Contemporary Guidelines for Managing Patients at High Genetic Risk of Coronary Artery Disease. | J Am Coll Cardiol | 01/06/2020 | 10.1016/j.jacc.2020.04.027 | 32498804 |
| PGP000102 | 1 | 3 | Mars N | The role of polygenic risk and susceptibility genes in breast cancer over the course of life | Nat Commun | 14/12/2020 | 10.1038/s41467-020-19966-5 | 33318493 |
| PGP000089 | 79 | 79 | Folkersen L | Genomic and drug target evaluation of 90 cardiovascular proteins in 30,931 individuals. | Nat Metab | 16/10/2020 | 10.1038/s42255-020-00287-2 | 33067605 |
| PGP000122 | 1 | 1 | Conti DV | Trans-ancestry genome-wide association meta-analysis of prostate cancer identifies new susceptibility loci and informs genetic risk prediction. | Nat Genet | 04/01/2021 | 10.1038/s41588-020-00748-0 | 33398198 |
| PGP000121 | 4 | 4 | Tam CHT | Development of genome-wide polygenic risk scores for lipid traits and clinical applications for dyslipidemia, subclinical atherosclerosis, and diabetes cardiovascular complications among East Asians. | Genome Med | 19/02/2021 | 10.1186/s13073-021-00831-z | 33608049 |
| PGP000189 | 2 | 2 | Dijk FN | Genetic risk scores do not improve asthma prediction in childhood. | J Allergy Clin Immunol | 27/05/2019 | 10.1016/j.jaci.2019.05.017 | 31145937 |
| PGP000190 | 1 | 1 | Hang D | Colorectal cancer susceptibility variants and risk of conventional adenomas and serrated polyps: results from three cohort studies. | Int J Epidemiol | 01/02/2020 | 10.1093/ije/dyz096 | 31038671 |
| PGP000126 | 1 | 1 | Pirruccello JP | Analysis of cardiac magnetic resonance imaging in 36,000 individuals yields genetic insights into dilated cardiomyopathy. | Nat Commun | 07/05/2020 | 10.1038/s41467-020-15823-7 | 32382064 |
| PGP000125 | 1 | 1 | Marston NA | Clinical Application of a Novel Genetic Risk Score for Ischemic Stroke in Patients with Cardiometabolic Disease. | Circulation | 13/11/2020 | 10.1161/circulationaha.120.051927 | 33185476 |
| PGP000127 | 1 | 1 | Trinder M | Clinical Utility of Lipoprotein(a) and LPA Genetic Risk Score in Risk Prediction of Incident Atherosclerotic Cardiovascular Disease. | JAMA Cardiol | 06/10/2020 | 10.1001/jamacardio.2020.5398 | 33021622 |
| PGP000123 | 1 | 1 | Kim J | Genetic and Circulating Biomarker Data Improve Risk Prediction for Pancreatic Cancer in the General Population. | Cancer Epidemiol Biomarkers Prev | 22/04/2020 | 10.1158/1055-9965.epi-19-1389 | 32321713 |
| PGP000135 | 7 | 8 | Jia G | Evaluating the Utility of Polygenic Risk Scores in Identifying High-Risk Individuals for Eight Common Cancers. | JNCI Cancer Spectr | 12/03/2020 | 10.1093/jncics/pkaa021 | 32596635 |
| PGP000136 | 1 | 1 | Emdin CA | Association of genetic variation with cirrhosis: a multi-trait genome-wide association and gene-environment interaction study. | Gastroenterology | 10/12/2020 | 10.1053/j.gastro.2020.12.011 | 33310085 |
| PGP000143 | 0 | 1 | Fahed AC | Transethnic Transferability of a Genome-Wide Polygenic Score for Coronary Artery Disease. | Circ Genom Precis Med | 07/12/2020 | 10.1161/circgen.120.003092 | 33284643 |
| PGP000124 | 1 | 1 | Gorski M | Meta-analysis uncovers genome-wide significant variants for rapid kidney function decline. | Kidney Int | 30/10/2020 | 10.1016/j.kint.2020.09.030 | 33137338 |
| PGP000129 | 0 | 1 | Mosley JD | Predictive Accuracy of a Polygenic Risk Score Compared With a Clinical Risk Score for Incident Coronary Heart Disease. | JAMA | 01/02/2020 | 10.1001/jama.2019.21782 | 32068817 |
| PGP000132 | 2 | 2 | Richardson TG | Use of genetic variation to separate the effects of early and later life adiposity on disease risk: mendelian randomisation study. | BMJ | 06/05/2020 | 10.1136/bmj.m1203 | 32376654 |
| PGP000133 | 0 | 1 | Naito T | Prevalence and Effect of Genetic Risk of Thromboembolic Disease in Inflammatory Bowel Disease. | Gastroenterology | 21/10/2020 | 10.1053/j.gastro.2020.10.019 | 33098885 |
| PGP000138 | 3 | 3 | Fontanillas P | Disease risk scores for skin cancers. | Nat Commun | 08/01/2021 | 10.1038/s41467-020-20246-5 | 33420020 |
| PGP000130 | 1 | 1 | Sipeky C | Prostate cancer risk prediction using a polygenic risk score. | Sci Rep | 13/10/2020 | 10.1038/s41598-020-74172-z | 33051487 |
| PGP000134 | 1 | 1 | Lanfear DE | Polygenic Score for β-Blocker Survival Benefit in European Ancestry Patients With Reduced Ejection Fraction Heart Failure. | Circ Heart Fail | 04/10/2020 | 10.1161/circheartfailure.119.007012 | 33012170 |
| PGP000128 | 46 | 46 | Sinnott-Armstrong N | Genetics of 35 blood and urine biomarkers in the UK Biobank. | Nat Genet | 18/01/2021 | 10.1038/s41588-020-00757-z | 33462484 |
| PGP000137 | 3 | 4 | Ritchie SC | Integrative analysis of the plasma proteome and polygenic risk of cardiometabolic diseases | bioRxivPre | 19/12/2019 | 10.1101/2019.12.14.876474 | — |
| PGP000140 | 0 | 2 | Brandkvist M | Separating the genetics of childhood and adult obesity: a validation study of genetic scores for body mass index in adolescence and adulthood in the HUNT Study. | Hum Mol Genet | 04/12/2020 | 10.1093/hmg/ddaa256 | 33276378 |
| PGP000141 | 0 | 1 | Brandkvist M | Genetic associations with temporal shifts in obesity and severe obesity during the obesity epidemic in Norway: A longitudinal population-based cohort (the HUNT Study). | PLoS Med | 14/12/2020 | 10.1371/journal.pmed.1003452 | 33315864 |
| PGP000142 | 1 | 1 | Archambault AN | Cumulative Burden of Colorectal Cancer-Associated Genetic Variants Is More Strongly Associated With Early-Onset vs Late-Onset Cancer. | Gastroenterology | 19/12/2019 | 10.1053/j.gastro.2019.12.012 | 31866242 |
| PGP000145 | 1 | 1 | Roberts GHL | Family Clustering of Autoimmune Vitiligo Results Principally from Polygenic Inheritance of Common Risk Alleles. | Am J Hum Genet | 18/07/2019 | 10.1016/j.ajhg.2019.06.013 | 31327509 |
| PGP000193 | 5 | 5 | Polfus LM | Genetic discovery and risk characterization in type 2 diabetes across diverse populations | Human Genetics and Genomics Advances | 08/04/2021 | 10.1016/j.xhgg.2021.100029 | — |
| PGP000144 | 3 | 3 | Tadros R | Predicting cardiac electrical response to sodium-channel blockade and Brugada syndrome using polygenic risk scores. | Eur Heart J | 01/10/2019 | 10.1093/eurheartj/ehz435 | 31504448 |
| PGP000146 | 1 | 1 | Harper AR | Common genetic variants and modifiable risk factors underpin hypertrophic cardiomyopathy susceptibility and expressivity. | Nat Genet | 25/01/2021 | 10.1038/s41588-020-00764-0 | 33495597 |
| PGP000168 | 0 | 1 | Plym A | Evaluation of a Multiethnic Polygenic Risk Score Model for Prostate Cancer. | J Natl Cancer Inst | 01/04/2021 | 10.1093/jnci/djab058 | 33792693 |
| PGP000167 | 0 | 3 | Maguire S | Common Susceptibility Loci for Male Breast Cancer. | J Natl Cancer Inst | 01/04/2021 | 10.1093/jnci/djaa101 | 32785646 |
| PGP000139 | 1 | 2 | Karunamuni RA | African-specific improvement of a polygenic hazard score for age at diagnosis of prostate cancer. | Int J Cancer | 24/09/2020 | 10.1002/ijc.33282 | 32930425 |
| PGP000164 | 3 | 3 | Khan Z | Genetic variation associated with thyroid autoimmunity shapes the systemic immune response to PD-1 checkpoint blockade. | Nat Commun | 07/06/2021 | 10.1038/s41467-021-23661-4 | 34099659 |
| PGP000162 | 2 | 2 | Ouyang H | Association between genetic risk scores and risk of narcolepsy: a case-control study. | Ann Transl Med | 01/02/2020 | 10.21037/atm.2019.12.95 | 32175396 |
| PGP000148 | 1 | 1 | Hung RJ | Assessing Lung Cancer Absolute Risk Trajectory Based on a Polygenic Risk Model. | Cancer Res | 20/01/2021 | 10.1158/0008-5472.can-20-1237 | 33472890 |
| PGP000147 | 0 | 11 | Thareja G | Whole genome sequencing in the Middle Eastern Qatari population identifies genetic associations with 45 clinically relevant traits. | Nat Commun | 23/02/2021 | 10.1038/s41467-021-21381-3 | 33623009 |
| PGP000149 | 1 | 1 | Huynh-Le MP | Polygenic hazard score is associated with prostate cancer in multi-ethnic populations. | Nat Commun | 23/02/2021 | 10.1038/s41467-021-21287-0 | 33623038 |
| PGP000169 | 1 | 1 | Cole BS | The Role of Genetic Ancestry as a Risk Factor for Primary Open-angle Glaucoma in African Americans. | Invest Ophthalmol Vis Sci | 01/02/2021 | 10.1167/iovs.62.2.28 | 33605984 |
| PGP000185 | 1 | 1 | Adel Fahmideh M | A Weighted Genetic Risk Score of Adult Glioma Susceptibility Loci Associated with Pediatric Brain Tumor Risk. | Sci Rep | 02/12/2019 | 10.1038/s41598-019-54701-1 | 31792337 |
| PGP000186 | 16 | 32 | Kachuri L | Pan-cancer analysis demonstrates that integrating polygenic risk scores with modifiable risk factors improves risk prediction. | Nat Commun | 27/11/2020 | 10.1038/s41467-020-19600-4 | 33247094 |
| PGP000188 | 0 | 1 | Tangtanatakul P | Meta-analysis of genome-wide association study identifies FBN2 as a novel locus associated with systemic lupus erythematosus in Thai population. | Arthritis Res Ther | 08/08/2020 | 10.1186/s13075-020-02276-y | 32771030 |
| PGP000151 | 3 | 3 | Cust AE | Assessing the Incremental Contribution of Common Genomic Variants to Melanoma Risk Prediction in Two Population-Based Studies. | J Invest Dermatol | 08/06/2018 | 10.1016/j.jid.2018.05.023 | 29890168 |
| PGP000192 | 1 | 1 | Kawai VK | Pleiotropy of systemic lupus erythematosus risk alleles and cardiometabolic disorders: A phenome-wide association study and inverse-variance weighted meta-analysis. | Lupus | 12/05/2021 | 10.1177/09612033211014952 | 33977795 |
| PGP000172 | 1 | 1 | Bakshi A | Genomic Risk Score for Melanoma in a Prospective Study of Older Individuals. | J Natl Cancer Inst | 10/04/2021 | 10.1093/jnci/djab076 | 33837773 |
| PGP000154 | 0 | 1 | Lu T | Improved prediction of fracture risk leveraging a genome-wide polygenic risk score. | Genome Med | 03/02/2021 | 10.1186/s13073-021-00838-6 | 33536041 |
| PGP000155 | 1 | 1 | Bobbili DR | Excess of singleton loss-of-function variants in Parkinson's disease contributes to genetic risk. | J Med Genet | 13/02/2020 | 10.1136/jmedgenet-2019-106316 | 32054687 |
| PGP000156 | 1 | 1 | Du Z | A genome-wide association study of prostate cancer in Latinos. | Int J Cancer | 03/07/2019 | 10.1002/ijc.32525 | 31226226 |
| PGP000157 | 1 | 1 | Dron JS | Genetic Predictor to Identify Individuals With High Lipoprotein(a) Concentrations. | Circ Genom Precis Med | 01/02/2021 | 10.1161/circgen.120.003182 | 33522245 |
| PGP000152 | 4 | 6 | Gola D | Population Bias in Polygenic Risk Prediction Models for Coronary Artery Disease. | Circ Genom Precis Med | 10/11/2020 | 10.1161/circgen.120.002932 | 33170024 |
| PGP000153 | 0 | 1 | Manousaki D | A Polygenic Risk Score as a Risk Factor for Medication-Associated Fractures. | J Bone Miner Res | 20/07/2020 | 10.1002/jbmr.4104 | 32511779 |
| PGP000150 | 1 | 2 | Karunamuni RA | Additional SNPs improve risk stratification of a polygenic hazard score for prostate cancer. | Prostate Cancer Prostatic Dis | 08/01/2021 | 10.1038/s41391-020-00311-2 | 33420416 |
| PGP000191 | 1 | 1 | He CY | Performance of common genetic variants in risk prediction for colorectal cancer in Chinese: A two-stage and multicenter study. | Genomics | 02/02/2021 | 10.1016/j.ygeno.2021.01.025 | 33545268 |
| PGP000161 | 1 | 1 | Cho SK | Polygenic analysis of the effect of common and low-frequency genetic variants on serum uric acid levels in Korean individuals. | Sci Rep | 08/06/2020 | 10.1038/s41598-020-66064-z | 32514006 |
| PGP000166 | 0 | 1 | Marston NA | Genetic Risk Score to Identify Risk of Venous Thromboembolism in Patients With Cardiometabolic Disease. | Circ Genom Precis Med | 12/01/2021 | 10.1161/circgen.120.003006 | 33434447 |
| PGP000159 | 1 | 1 | Klarin D | Genetic Architecture of Abdominal Aortic Aneurysm in the Million Veteran Program. | Circulation | 28/09/2020 | 10.1161/circulationaha.120.047544 | 32981348 |
| PGP000160 | 1 | 1 | Wang YF | Identification of 38 novel loci for systemic lupus erythematosus and genetic heterogeneity between ancestral groups. | Nat Commun | 03/02/2021 | 10.1038/s41467-021-21049-y | 33536424 |
| PGP000163 | 1 | 1 | Lu T | A polygenic risk score to predict future adult short stature amongst children. | J Clin Endocrinol Metab | 31/03/2021 | 10.1210/clinem/dgab215 | 33788949 |
| PGP000170 | 1 | 0 | Huyghe JR | Discovery of common and rare genetic risk variants for colorectal cancer. | Nat Genet | 03/12/2018 | 10.1038/s41588-018-0286-6 | 30510241 |
| PGP000165 | 2 | 2 | Cherny SS | Self-reported hearing loss questions provide a good measure for genetic studies: a polygenic risk score analysis from UK Biobank. | Eur J Hum Genet | 20/03/2020 | 10.1038/s41431-020-0603-2 | 32203203 |
| PGP000171 | 0 | 2 | Fahed AC | Polygenic background modifies penetrance of monogenic variants for tier 1 genomic conditions. | Nat Commun | 20/08/2020 | 10.1038/s41467-020-17374-3 | 32820175 |
| PGP000176 | 1 | 1 | Sordillo JE | Pharmacogenetic Polygenic Risk Score for Bronchodilator Response in Children and Adolescents with Asthma: Proof-of-Concept. | J Pers Med | 20/04/2021 | 10.3390/jpm11040319 | 33923870 |
| PGP000177 | 1 | 1 | de Toro-Martín J | The Challenge of Stratifying Obesity: Attempts in the Quebec Family Study. | Front Genet | 10/10/2019 | 10.3389/fgene.2019.00994 | 31649740 |
| PGP000181 | 1 | 1 | Liu G | Genome-wide survival study identifies a novel synaptic locus and polygenic score for cognitive progression in Parkinson's disease. | Nat Genet | 06/05/2021 | 10.1038/s41588-021-00847-6 | 33958783 |
| PGP000187 | 1 | 1 | Severance LM | Using a genetic risk score to calculate the optimal age for an individual to undergo coronary artery calcium screening. | J Cardiovasc Comput Tomogr | 09/05/2019 | 10.1016/j.jcct.2019.05.005 | 31104941 |
| PGP000182 | 1 | 2 | Tadros R | Shared genetic pathways contribute to risk of hypertrophic and dilated cardiomyopathies with opposite directions of effect. | Nat Genet | 25/01/2021 | 10.1038/s41588-020-00762-2 | 33495596 |
| PGP000173 | 0 | 2 | Darst BF | Combined Effect of a Polygenic Risk Score and Rare Genetic Variants on Prostate Cancer Risk. | Eur Urol | 01/05/2021 | 10.1016/j.eururo.2021.04.013 | 33941403 |
| PGP000174 | 1 | 1 | Guffanti G | Depression genetic risk score is associated with anhedonia-related markers across units of analysis. | Transl Psychiatry | 19/09/2019 | 10.1038/s41398-019-0566-7 | 31537779 |
| PGP000178 | 2 | 2 | Chen L | Genome-wide assessment of genetic risk for systemic lupus erythematosus and disease severity. | Hum Mol Genet | 01/06/2020 | 10.1093/hmg/ddaa030 | 32077931 |
| PGP000179 | 3 | 6 | Du Z | Evaluating Polygenic Risk Scores for Breast Cancer in Women of African Ancestry. | J Natl Cancer Inst | 26/03/2021 | 10.1093/jnci/djab050 | 33769540 |
| PGP000180 | 1 | 1 | Innes H | Genome-Wide Association Study for Alcohol-Related Cirrhosis Identifies Risk Loci in MARC1 and HNRNPUL1. | Gastroenterology | 16/06/2020 | 10.1053/j.gastro.2020.06.014 | 32561361 |
| PGP000183 | 1 | 1 | Zhou X | Genetic and polygenic risk score analysis for Alzheimer's disease in the Chinese population. | Alzheimers Dement (Amst) | 05/08/2020 | 10.1002/dad2.12074 | 32775599 |
| PGP000184 | 1 | 1 | Clark H | Differential associations of allergic disease genetic variants with developmental profiles of eczema, wheeze and rhinitis. | Clin Exp Allergy | 15/10/2019 | 10.1111/cea.13485 | 31441980 |
| PGP000175 | 1 | 1 | Lahrouchi N | Transethnic Genome-Wide Association Study Provides Insights in the Genetic Architecture and Heritability of Long QT Syndrome. | Circulation | 20/05/2020 | 10.1161/circulationaha.120.045956 | 32429735 |