| PGS Publication/Study (PGP) ID | PGS Developed | PGS Evaluated | First Author | Title | Journal Name | Publication Date | Digital object identifier (doi) | PubMed ID (PMID) |
|---|---|---|---|---|---|---|---|---|
| PGP000095 | 2 | 2 | Meisner A | Combined Utility of 25 Disease and Risk Factor Polygenic Risk Scores for Stratifying Risk of All-Cause Mortality. | Am J Hum Genet | 07/26/2020 | 10.1016/j.ajhg.2020.07.002 | 32758451 |
| PGP000055 | 3 | 3 | Fritsche LG | Exploring various polygenic risk scores for skin cancer in the phenomes of the Michigan genomics initiative and the UK Biobank with a visual catalog: PRSWeb. | PLoS Genet | 06/13/2019 | 10.1371/journal.pgen.1008202 | 31194742 |
| PGP000028 | 1 | 1 | Abraham G | Accurate and robust genomic prediction of celiac disease using statistical learning. | PLoS Genet | 02/13/2014 | 10.1371/journal.pgen.1004137 | 24550740 |
| PGP000029 | 2 | 3 | Abraham G | Genomic prediction of celiac disease targeting HLA-positive individuals. | Genome Med | 07/16/2015 | 10.1186/s13073-015-0196-5 | 26244058 |
| PGP000068 | 8 | 8 | Cai N | Minimal phenotyping yields genome-wide association signals of low specificity for major depression. | Nat Genet | 03/30/2020 | 10.1038/s41588-020-0594-5 | 32231276 |
| PGP000072 | 1 | 1 | Smith T | The added value of genetic information in colorectal cancer risk prediction models: development and evaluation in the UK Biobank prospective cohort study. | Br J Cancer | 10/16/2018 | 10.1038/s41416-018-0282-8 | 30323197 |
| PGP000004 | 1 | 2 | Tada H | Risk prediction by genetic risk scores for coronary heart disease is independent of self-reported family history. | Eur Heart J | 09/20/2015 | 10.1093/eurheartj/ehv462 | 26392438 |
| PGP000005 | 1 | 2 | Abraham G | Genomic prediction of coronary heart disease. | Eur Heart J | 09/21/2016 | 10.1093/eurheartj/ehw450 | 27655226 |
| PGP000069 | 1 | 1 | Hsu L | A model to determine colorectal cancer risk using common genetic susceptibility loci. | Gastroenterology | 02/13/2015 | 10.1053/j.gastro.2015.02.010 | 25683114 |
| PGP000070 | 1 | 1 | Ibáñez-Sanz G | Risk Model for Colorectal Cancer in Spanish Population Using Environmental and Genetic Factors: Results from the MCC-Spain study. | Sci Rep | 02/24/2017 | 10.1038/srep43263 | 28233817 |
| PGP000071 | 1 | 1 | Jeon J | Determining Risk of Colorectal Cancer and Starting Age of Screening Based on Lifestyle, Environmental, and Genetic Factors. | Gastroenterology | 02/17/2018 | 10.1053/j.gastro.2018.02.021 | 29458155 |
| PGP000088 | 5 | 7 | Zhang H | Genome-wide association study identifies 32 novel breast cancer susceptibility loci from overall and subtype-specific analyses. | Nat Genet | 05/18/2020 | 10.1038/s41588-020-0609-2 | 32424353 |
| PGP000073 | 1 | 1 | Weigl K | Genetic Risk Score Is Associated With Prevalence of Advanced Neoplasms in a Colorectal Cancer Screening Population. | Gastroenterology | 03/21/2018 | 10.1053/j.gastro.2018.03.030 | 29574091 |
| PGP000075 | 11 | 11 | Shi Z | Systematic evaluation of cancer-specific genetic risk score for 11 types of cancer in The Cancer Genome Atlas and Electronic Medical Records and Genomics cohorts. | Cancer Med | 04/09/2019 | 10.1002/cam4.2143 | 30968590 |
| PGP000058 | 0 | 1 | Huynh-Le M | Polygenic hazard score predicts aggressive and fatal prostate cancer in multi-ethnic populations | medRxivPre | 11/19/2019 | 10.1101/19012237 | — |
| PGP000030 | 1 | 1 | Klarin D | Genome-wide association analysis of venous thromboembolism identifies new risk loci and genetic overlap with arterial vascular disease. | Nat Genet | 11/01/2019 | 10.1038/s41588-019-0519-3 | 31676865 |
| PGP000031 | 1 | 1 | Pashayan N | Reducing overdiagnosis by polygenic risk-stratified screening: findings from the Finnish section of the ERSPC. | Br J Cancer | 08/20/2015 | 10.1038/bjc.2015.289 | 26291059 |
| PGP000032 | 0 | 1 | Pashayan N | Implications of polygenic risk-stratified screening for prostate cancer on overdiagnosis. | Genet Med | 01/08/2015 | 10.1038/gim.2014.192 | 25569441 |
| PGP000033 | 4 | 7 | Kuchenbaecker KB | Evaluation of Polygenic Risk Scores for Breast and Ovarian Cancer Risk Prediction in BRCA1 and BRCA2 Mutation Carriers. | J Natl Cancer Inst | 07/01/2017 | 10.1093/jnci/djw302 | 28376175 |
| PGP000034 | 1 | 4 | Lecarpentier J | Prediction of Breast and Prostate Cancer Risks in Male BRCA1 and BRCA2 Mutation Carriers Using Polygenic Risk Scores. | J Clin Oncol | 04/27/2017 | 10.1200/JCO.2016.69.4935 | 28448241 |
| PGP000096 | 1 | 1 | Chami N | The role of polygenic susceptibility to obesity among carriers of pathogenic mutations in MC4R in the UK Biobank population. | PLoS Med | 07/21/2020 | 10.1371/journal.pmed.1003196 | 32692746 |
| PGP000035 | 1 | 1 | Wen W | Prediction of breast cancer risk based on common genetic variants in women of East Asian ancestry. | Breast Cancer Res | 12/08/2016 | 10.1186/s13058-016-0786-1 | 27931260 |
| PGP000036 | 1 | 1 | Zhang X | Addition of a polygenic risk score, mammographic density, and endogenous hormones to existing breast cancer risk prediction models: A nested case-control study. | PLoS Med | 09/04/2018 | 10.1371/journal.pmed.1002644 | 30180161 |
| PGP000037 | 1 | 1 | Lakeman IMM | Addition of a 161-SNP polygenic risk score to family history-based risk prediction: impact on clinical management in non-BRCA1/2 breast cancer families. | J Med Genet | 06/11/2019 | 10.1136/jmedgenet-2019-106072 | 31186341 |
| PGP000079 | 1 | 1 | Kathiresan S | Polymorphisms associated with cholesterol and risk of cardiovascular events. | N Engl J Med | 03/01/2008 | 10.1056/nejmoa0706728 | 18354102 |
| PGS000080 | 1 | 1 | Coleman JRI | Genome-wide gene-environment analyses of major depressive disorder and reported lifetime traumatic experiences in UK Biobank. | Mol Psychiatry | 01/23/2020 | 10.1038/s41380-019-0546-6 | 31969693 |
| PGP000009 | 1 | 1 | Paquette M | Polygenic risk score predicts prevalence of cardiovascular disease in patients with familial hypercholesterolemia. | J Clin Lipidol | 04/06/2017 | 10.1016/j.jacl.2017.03.019 | 28456682 |
| PGP000010 | 1 | 1 | Läll K | Personalized risk prediction for type 2 diabetes: the potential of genetic risk scores. | Genet Med | 08/11/2016 | 10.1038/gim.2016.103 | 27513194 |
| PGP000097 | 3 | 3 | Flynn E | Sex-specific genetic effects across biomarkers. | Eur J Hum Genet | 09/01/2020 | 10.1038/s41431-020-00712-w | 32873964 |
| PGP000011 | 1 | 1 | Oram RA | A Type 1 Diabetes Genetic Risk Score Can Aid Discrimination Between Type 1 and Type 2 Diabetes in Young Adults. | Diabetes Care | 11/17/2015 | 10.2337/dc15-1111 | 26577414 |
| PGP000041 | 1 | 1 | Paul KC | Association of Polygenic Risk Score With Cognitive Decline and Motor Progression in Parkinson Disease. | JAMA Neurol | 03/01/2018 | 10.1001/jamaneurol.2017.4206 | 29340614 |
| PGP000076 | 0 | 1 | Khera AV | Genetic Risk, Adherence to a Healthy Lifestyle, and Coronary Disease. | N Engl J Med | 11/13/2016 | 10.1056/NEJMoa1605086 | 27959714 |
| PGP000077 | 0 | 1 | Timmerman N | Family history and polygenic risk of cardiovascular disease: independent factors associated with secondary cardiovascular manifestations in patients undergoing carotid endarterectomy | medRxivPre | 09/18/2019 | 10.1101/19006718 | — |
| PGP000018 | 2 | 2 | Shieh Y | Breast cancer risk prediction using a clinical risk model and polygenic risk score. | Breast Cancer Res Treat | 08/26/2016 | 10.1007/s10549-016-3953-2 | 27565998 |
| PGP000078 | 29 | 27 | Vuckovic D | The Polygenic and Monogenic Basis of Blood Traits and Diseases | medRxivPre | 02/03/2020 | 10.1101/2020.02.02.20020065 | — |
| PGP000081 | 6 | 6 | Knevel R | Using genetics to prioritize diagnoses for rheumatology outpatients with inflammatory arthritis. | Sci Transl Med | 05/01/2020 | 10.1126/scitranslmed.aay1548 | 32461333 |
| PGP000001 | 3 | 3 | Mavaddat N | Prediction of breast cancer risk based on profiling with common genetic variants. | J Natl Cancer Inst | 04/08/2015 | 10.1093/jnci/djv036 | 25855707 |
| PGP000002 | 6 | 9 | Mavaddat N | Polygenic Risk Scores for Prediction of Breast Cancer and Breast Cancer Subtypes. | Am J Hum Genet | 12/13/2018 | 10.1016/j.ajhg.2018.11.002 | 30554720 |
| PGP000074 | 1 | 1 | Xin J | Evaluating the effect of multiple genetic risk score models on colorectal cancer risk prediction. | Gene | 06/14/2018 | 10.1016/j.gene.2018.06.035 | 29908285 |
| PGP000016 | 1 | 1 | Desikan RS | Genetic assessment of age-associated Alzheimer disease risk: Development and validation of a polygenic hazard score. | PLoS Med | 03/21/2017 | 10.1371/journal.pmed.1002258 | 28323831 |
| PGP000017 | 1 | 1 | Khera AV | Polygenic Prediction of Weight and Obesity Trajectories from Birth to Adulthood. | Cell | 04/01/2019 | 10.1016/j.cell.2019.03.028 | 31002795 |
| PGP000019 | 1 | 1 | Schumacher FR | Association analyses of more than 140,000 men identify 63 new prostate cancer susceptibility loci. | Nat Genet | 06/11/2018 | 10.1038/s41588-018-0142-8 | 29892016 |
| PGP000022 | 1 | 1 | Weng LC | Genetic Predisposition, Clinical Risk Factor Burden, and Lifetime Risk of Atrial Fibrillation. | Circulation | 11/12/2017 | 10.1161/CIRCULATIONAHA.117.031431 | 29129827 |
| PGP000091 | 0 | 1 | Ferrat LA | A combined risk score enhances prediction of type 1 diabetes among susceptible children. | Nat Med | 08/07/2020 | 10.1038/s41591-020-0930-4 | 32770166 |
| PGP000090 | 1 | 2 | Wang M | Validation of a Genome-Wide Polygenic Score for Coronary Artery Disease in South Asians. | J Am Coll Cardiol | 08/01/2020 | 10.1016/j.jacc.2020.06.024 | 32762905 |
| PGP000083 | 0 | 4 | Dikilitas O | Predictive Utility of Polygenic Risk Scores for Coronary Heart Disease in Three Major Racial and Ethnic Groups. | Am J Hum Genet | 05/01/2020 | 10.1016/j.ajhg.2020.04.002 | 32386537 |
| PGP000082 | 1 | 1 | Tikkanen E | Genetic risk prediction and a 2-stage risk screening strategy for coronary heart disease. | Arterioscler Thromb Vasc Biol | 04/18/2013 | 10.1161/atvbaha.112.301120 | 23599444 |
| PGP000003 | 1 | 1 | Mega JL | Genetic risk, coronary heart disease events, and the clinical benefit of statin therapy: an analysis of primary and secondary prevention trials. | Lancet | 03/04/2015 | 10.1016/S0140-6736(14)61730-X | 25748612 |
| PGP000093 | 1 | 1 | Sharp SA | A single nucleotide polymorphism genetic risk score to aid diagnosis of coeliac disease: a pilot study in clinical care. | Aliment Pharmacol Ther | 08/13/2020 | 10.1111/apt.15826 | 32790217 |
| PGP000092 | 19 | 19 | Xie T | Genetic Risk Scores for Complex Disease Traits in Youth. | Circ Genom Precis Med | 06/11/2020 | 10.1161/circgen.119.002775 | 32527150 |
| PGP000084 | 6 | 6 | Barr PB | Using polygenic scores for identifying individuals at increased risk of substance use disorders in clinical and population samples. | Transl Psychiatry | 06/18/2020 | 10.1038/s41398-020-00865-8 | 32555147 |
| PGP000020 | 3 | 3 | Vassy JL | Polygenic type 2 diabetes prediction at the limit of common variant detection. | Diabetes | 02/11/2014 | 10.2337/db13-1663 | 24520119 |
| PGP000021 | 1 | 1 | Song M | Longitudinal Analysis of Genetic Susceptibility and BMI Throughout Adult Life. | Diabetes | 12/06/2017 | 10.2337/db17-1156 | 29212779 |
| PGP000094 | 1 | 1 | Shieh Y | A Polygenic Risk Score for Breast Cancer in US Latinas and Latin American Women. | J Natl Cancer Inst | 06/01/2020 | 10.1093/jnci/djz174 | 31553449 |
| PGP000006 | 5 | 5 | Khera AV | Genome-wide polygenic scores for common diseases identify individuals with risk equivalent to monogenic mutations. | Nat Genet | 08/13/2018 | 10.1038/s41588-018-0183-z | 30104762 |
| PGP000046 | 3 | 3 | Kuchenbaecker K | The transferability of lipid loci across African, Asian and European cohorts. | Nat Commun | 09/24/2019 | 10.1038/s41467-019-12026-7 | 31551420 |
| PGP000023 | 1 | 0 | Mahajan A | Fine-mapping type 2 diabetes loci to single-variant resolution using high-density imputation and islet-specific epigenome maps. | Nat Genet | 10/08/2018 | 10.1038/s41588-018-0241-6 | 30297969 |
| PGP000024 | 0 | 1 | Udler MS | Genetic Risk Scores for Diabetes Diagnosis and Precision Medicine. | Endocr Rev | 12/01/2019 | 10.1210/er.2019-00088 | 31322649 |
| PGP000025 | 1 | 1 | Belsky DW | Polygenic risk and the development and course of asthma: an analysis of data from a four-decade longitudinal study. | Lancet Respir Med | 06/28/2013 | 10.1016/S2213-2600(13)70101-2 | 24429243 |
| PGP000008 | 0 | 2 | Wünnemann F | Validation of Genome-Wide Polygenic Risk Scores for Coronary Artery Disease in French Canadians. | Circ Genom Precis Med | 06/11/2019 | 10.1161/CIRCGEN.119.002481 | 31184202 |
| PGP000026 | 1 | 1 | Rutten-Jacobs LC | Genetic risk, incident stroke, and the benefits of adhering to a healthy lifestyle: cohort study of 306 473 UK Biobank participants. | BMJ | 10/24/2018 | 10.1136/bmj.k4168 | 30355576 |
| PGP000027 | 1 | 2 | Abraham G | Genomic risk score offers predictive performance comparable to clinical risk factors for ischaemic stroke. | Nat Commun | 12/20/2019 | 10.1038/s41467-019-13848-1 | 31862893 |
| PGP000066 | 1 | 1 | Craig JE | Multitrait analysis of glaucoma identifies new risk loci and enables polygenic prediction of disease susceptibility and progression. | Nat Genet | 01/20/2020 | 10.1038/s41588-019-0556-y | 31959993 |
| PGP000038 | 0 | 1 | Patel KA | Type 1 Diabetes Genetic Risk Score: A Novel Tool to Discriminate Monogenic and Type 1 Diabetes. | Diabetes | 04/05/2016 | 10.2337/db15-1690 | 27207547 |
| PGP000039 | 2 | 2 | Tosto G | Polygenic risk scores in familial Alzheimer disease. | Neurology | 02/17/2017 | 10.1212/WNL.0000000000003734 | 28213371 |
| PGP000040 | 1 | 1 | Schmit SL | Novel Common Genetic Susceptibility Loci for Colorectal Cancer. | J Natl Cancer Inst | 02/01/2019 | 10.1093/jnci/djy099 | 29917119 |
| PGP000042 | 1 | 1 | Natarajan P | Polygenic Risk Score Identifies Subgroup With Higher Burden of Atherosclerosis and Greater Relative Benefit From Statin Therapy in the Primary Prevention Setting. | Circulation | 02/21/2017 | 10.1161/CIRCULATIONAHA.116.024436 | 28223407 |
| PGP000043 | 1 | 1 | Morieri ML | Genetic Tools for Coronary Risk Assessment in Type 2 Diabetes: A Cohort Study From the ACCORD Clinical Trial. | Diabetes Care | 09/27/2018 | 10.2337/dc18-0709 | 30262460 |
| PGP000007 | 1 | 3 | Inouye M | Genomic Risk Prediction of Coronary Artery Disease in 480,000 Adults: Implications for Primary Prevention. | J Am Coll Cardiol | 10/01/2018 | 10.1016/j.jacc.2018.07.079 | 30309464 |
| PGP000012 | 1 | 1 | Perry DJ | Application of a Genetic Risk Score to Racially Diverse Type 1 Diabetes Populations Demonstrates the Need for Diversity in Risk-Modeling. | Sci Rep | 03/14/2018 | 10.1038/s41598-018-22574-5 | 29540798 |
| PGP000013 | 1 | 2 | Onengut-Gumuscu S | Type 1 Diabetes Risk in African-Ancestry Participants and Utility of an Ancestry-Specific Genetic Risk Score. | Diabetes Care | 01/18/2019 | 10.2337/dc18-1727 | 30659077 |
| PGP000044 | 1 | 1 | Hajek C | Coronary Heart Disease Genetic Risk Score Predicts Cardiovascular Disease Risk in Men, Not Women. | Circ Genom Precis Med | 10/01/2018 | 10.1161/CIRCGEN.118.002324 | 30354305 |
| PGP000045 | 4 | 4 | Johnson L | An Examination of the Relationship between Lipid Levels and Associated Genetic Markers across Racial/Ethnic Populations in the Multi-Ethnic Study of Atherosclerosis. | PLoS One | 05/07/2015 | 10.1371/journal.pone.0126361 | 25951326 |
| PGP000047 | 1 | 1 | Seibert TM | Polygenic hazard score to guide screening for aggressive prostate cancer: development and validation in large scale cohorts. | BMJ | 01/10/2018 | 10.1136/bmj.j5757 | 29321194 |
| PGP000048 | 2 | 2 | Yang X | Evaluation of polygenic risk scores for ovarian cancer risk prediction in a prospective cohort study. | J Med Genet | 05/05/2018 | 10.1136/jmedgenet-2018-105313 | 29730597 |
| PGP000085 | 3 | 3 | Liyanarachchi S | Assessing thyroid cancer risk using polygenic risk scores. | Proc Natl Acad Sci U S A | 03/04/2020 | 10.1073/pnas.1919976117 | 32132206 |
| PGP000014 | 1 | 2 | Sharp SA | Development and Standardization of an Improved Type 1 Diabetes Genetic Risk Score for Use in Newborn Screening and Incident Diagnosis. | Diabetes Care | 02/01/2019 | 10.2337/dc18-1785 | 30655379 |
| PGP000015 | 1 | 1 | Chouraki V | Evaluation of a Genetic Risk Score to Improve Risk Prediction for Alzheimer's Disease. | J Alzheimers Dis | 06/01/2016 | 10.3233/JAD-150749 | 27340842 |
| PGP000062 | 1 | 1 | Qi Q | Genetics of Type 2 Diabetes in U.S. Hispanic/Latino Individuals: Results From the Hispanic Community Health Study/Study of Latinos (HCHS/SOL). | Diabetes | 03/02/2017 | 10.2337/db16-1150 | 28254843 |
| PGP000086 | 1 | 1 | Shrine N | New genetic signals for lung function highlight pathways and chronic obstructive pulmonary disease associations across multiple ancestries. | Nat Genet | 02/25/2019 | 10.1038/s41588-018-0321-7 | 30804560 |
| PGP000049 | 1 | 1 | Dai J | Identification of risk loci and a polygenic risk score for lung cancer: a large-scale prospective cohort study in Chinese populations. | Lancet Respir Med | 07/17/2019 | 10.1016/S2213-2600(19)30144-4 | 31326317 |
| PGP000050 | 17 | 17 | Graff RE | Cross-Cancer Evaluation of Polygenic Risk Scores for 17 Cancer Types in Two Large Cohorts | bioRxivPre | 01/19/2020 | 10.1101/2020.01.18.911578 | — |
| PGP000051 | 26 | 26 | Xu Y | Learning polygenic scores for human blood cell traits | bioRxivPre | 02/18/2020 | 10.1101/2020.02.17.952788 | — |
| PGP000052 | 1 | 1 | Canovas R | Genomic risk scores for juvenile idiopathic arthritis and its subtypes | medRxivPre | 02/23/2020 | 10.1101/2020.02.20.20025924 | — |
| PGP000053 | 1 | 1 | Trinder M | Association of Monogenic vs Polygenic Hypercholesterolemia With Risk of Atherosclerotic Cardiovascular Disease. | JAMA Cardiol | 02/12/2020 | 10.1001/jamacardio.2019.5954 | 32049305 |
| PGP000054 | 2 | 2 | Elliott J | Predictive Accuracy of a Polygenic Risk Score-Enhanced Prediction Model vs a Clinical Risk Score for Coronary Artery Disease. | JAMA | 02/01/2020 | 10.1001/jama.2019.22241 | 32068818 |
| PGP000056 | 2 | 2 | Ho-Le TP | Prediction of Bone Mineral Density and Fragility Fracture by Genetic Profiling. | J Bone Miner Res | 10/26/2016 | 10.1002/jbmr.2998 | 27649491 |
| PGP000057 | 0 | 3 | Homburger JR | Low coverage whole genome sequencing enables accurate assessment of common variants and calculation of genome-wide polygenic scores. | Genome Med | 11/26/2019 | 10.1186/s13073-019-0682-2 | 31771638 |
| PGP000059 | 1 | 1 | Ibanez L | Parkinson disease polygenic risk score is associated with Parkinson disease status and age at onset but not with alpha-synuclein cerebrospinal fluid levels. | BMC Neurol | 11/15/2017 | 10.1186/s12883-017-0978-z | 29141588 |
| PGP000060 | 0 | 1 | Khera AV | Whole-Genome Sequencing to Characterize Monogenic and Polygenic Contributions in Patients Hospitalized With Early-Onset Myocardial Infarction. | Circulation | 03/01/2019 | 10.1161/circulationaha.118.035658 | 30586733 |
| PGP000061 | 1 | 1 | MacGregor S | Genome-wide association study of intraocular pressure uncovers new pathways to glaucoma. | Nat Genet | 07/27/2018 | 10.1038/s41588-018-0176-y | 30054594 |
| PGP000063 | 1 | 1 | Tin A | Target genes, variants, tissues and transcriptional pathways influencing human serum urate levels. | Nat Genet | 10/02/2019 | 10.1038/s41588-019-0504-x | 31578528 |
| PGP000064 | 6 | 6 | Wheeler E | Impact of common genetic determinants of Hemoglobin A1c on type 2 diabetes risk and diagnosis in ancestrally diverse populations: A transethnic genome-wide meta-analysis. | PLoS Med | 09/12/2017 | 10.1371/journal.pmed.1002383 | 28898252 |
| PGP000065 | 4 | 4 | Zheutlin AB | Penetrance and Pleiotropy of Polygenic Risk Scores for Schizophrenia in 106,160 Patients Across Four Health Care Systems. | Am J Psychiatry | 08/16/2019 | 10.1176/appi.ajp.2019.18091085 | 31416338 |
| PGP000087 | 1 | 1 | Pihlstrøm L | A cumulative genetic risk score predicts progression in Parkinson's disease. | Mov Disord | 02/08/2016 | 10.1002/mds.26505 | 26853697 |