Publications

PGS Publication/Study ID (PGP) PGS Developed PGS Evaluated First Author Title Journal Name Publication Date Digital object identifier (doi) PubMed ID (PMID)
PGP000069 1 1 Hsu L A model to determine colorectal cancer risk using common genetic susceptibility loci. Gastroenterology 13/02/2015 10.1053/j.gastro.2015.02.010 25683114
PGP000068 8 8 Cai N Minimal phenotyping yields genome-wide association signals of low specificity for major depression. Nat Genet 30/03/2020 10.1038/s41588-020-0594-5 32231276
PGP000066 1 1 Craig JE Multitrait analysis of glaucoma identifies new risk loci and enables polygenic prediction of disease susceptibility and progression. Nat Genet 20/01/2020 10.1038/s41588-019-0556-y 31959993
PGP000065 4 4 Zheutlin AB Penetrance and Pleiotropy of Polygenic Risk Scores for Schizophrenia in 106,160 Patients Across Four Health Care Systems. Am J Psychiatry 16/08/2019 10.1176/appi.ajp.2019.18091085 31416338
PGP000064 6 6 Wheeler E Impact of common genetic determinants of Hemoglobin A1c on type 2 diabetes risk and diagnosis in ancestrally diverse populations: A transethnic genome-wide meta-analysis. PLoS Med 12/09/2017 10.1371/journal.pmed.1002383 28898252
PGP000063 1 1 Tin A Target genes, variants, tissues and transcriptional pathways influencing human serum urate levels. Nat Genet 02/10/2019 10.1038/s41588-019-0504-x 31578528
PGP000062 1 1 Qi Q Genetics of Type 2 Diabetes in U.S. Hispanic/Latino Individuals: Results From the Hispanic Community Health Study/Study of Latinos (HCHS/SOL). Diabetes 02/03/2017 10.2337/db16-1150 28254843
PGP000061 1 1 MacGregor S Genome-wide association study of intraocular pressure uncovers new pathways to glaucoma. Nat Genet 27/07/2018 10.1038/s41588-018-0176-y 30054594
PGP000060 0 1 Khera AV Whole-Genome Sequencing to Characterize Monogenic and Polygenic Contributions in Patients Hospitalized With Early-Onset Myocardial Infarction. Circulation 01/03/2019 10.1161/circulationaha.118.035658 30586733
PGP000059 1 1 Ibanez L Parkinson disease polygenic risk score is associated with Parkinson disease status and age at onset but not with alpha-synuclein cerebrospinal fluid levels. BMC Neurol 15/11/2017 10.1186/s12883-017-0978-z 29141588
PGP000058 0 1 Huynh-Le M Polygenic hazard score predicts aggressive and fatal prostate cancer in multi-ethnic populations medRxivPre 19/11/2019 10.1101/19012237 —
PGP000057 0 3 Homburger JR Low coverage whole genome sequencing enables accurate assessment of common variants and calculation of genome-wide polygenic scores. Genome Med 26/11/2019 10.1186/s13073-019-0682-2 31771638
PGP000056 2 2 Ho-Le TP Prediction of Bone Mineral Density and Fragility Fracture by Genetic Profiling. J Bone Miner Res 26/10/2016 10.1002/jbmr.2998 27649491
PGP000055 3 3 Fritsche LG Exploring various polygenic risk scores for skin cancer in the phenomes of the Michigan genomics initiative and the UK Biobank with a visual catalog: PRSWeb. PLoS Genet 13/06/2019 10.1371/journal.pgen.1008202 31194742
PGP000054 2 2 Elliott J Predictive Accuracy of a Polygenic Risk Score-Enhanced Prediction Model vs a Clinical Risk Score for Coronary Artery Disease. JAMA 01/02/2020 10.1001/jama.2019.22241 32068818
PGP000053 1 1 Trinder M Association of Monogenic vs Polygenic Hypercholesterolemia With Risk of Atherosclerotic Cardiovascular Disease. JAMA Cardiol 12/02/2020 10.1001/jamacardio.2019.5954 32049305
PGP000052 4 4 Cánovas R Genomic risk scores for juvenile idiopathic arthritis and its subtypes. Ann Rheum Dis 04/09/2020 10.1136/annrheumdis-2020-217421 32887683
PGP000051 26 26 Xu Y Machine learning optimized polygenic scores for blood cell traits identify sex-specific trajectories and genetic correlations with disease Cell Genom 12/01/2022 10.1016/j.xgen.2021.100086 35072137
PGP000050 16 16 Graff RE Cross-cancer evaluation of polygenic risk scores for 16 cancer types in two large cohorts. Nat Commun 12/02/2021 10.1038/s41467-021-21288-z 33579919
PGP000049 1 1 Dai J Identification of risk loci and a polygenic risk score for lung cancer: a large-scale prospective cohort study in Chinese populations. Lancet Respir Med 17/07/2019 10.1016/S2213-2600(19)30144-4 31326317
PGP000048 2 2 Yang X Evaluation of polygenic risk scores for ovarian cancer risk prediction in a prospective cohort study. J Med Genet 05/05/2018 10.1136/jmedgenet-2018-105313 29730597
PGP000047 1 1 Seibert TM Polygenic hazard score to guide screening for aggressive prostate cancer: development and validation in large scale cohorts. BMJ 10/01/2018 10.1136/bmj.j5757 29321194
PGP000046 3 3 Kuchenbaecker K The transferability of lipid loci across African, Asian and European cohorts. Nat Commun 24/09/2019 10.1038/s41467-019-12026-7 31551420
PGP000045 4 4 Johnson L An Examination of the Relationship between Lipid Levels and Associated Genetic Markers across Racial/Ethnic Populations in the Multi-Ethnic Study of Atherosclerosis. PLoS One 07/05/2015 10.1371/journal.pone.0126361 25951326
PGP000044 1 1 Hajek C Coronary Heart Disease Genetic Risk Score Predicts Cardiovascular Disease Risk in Men, Not Women. Circ Genom Precis Med 01/10/2018 10.1161/CIRCGEN.118.002324 30354305
PGP000043 1 1 Morieri ML Genetic Tools for Coronary Risk Assessment in Type 2 Diabetes: A Cohort Study From the ACCORD Clinical Trial. Diabetes Care 27/09/2018 10.2337/dc18-0709 30262460
PGP000042 1 1 Natarajan P Polygenic Risk Score Identifies Subgroup With Higher Burden of Atherosclerosis and Greater Relative Benefit From Statin Therapy in the Primary Prevention Setting. Circulation 21/02/2017 10.1161/CIRCULATIONAHA.116.024436 28223407
PGP000041 1 1 Paul KC Association of Polygenic Risk Score With Cognitive Decline and Motor Progression in Parkinson Disease. JAMA Neurol 01/03/2018 10.1001/jamaneurol.2017.4206 29340614
PGP000040 1 1 Schmit SL Novel Common Genetic Susceptibility Loci for Colorectal Cancer. J Natl Cancer Inst 01/02/2019 10.1093/jnci/djy099 29917119
PGP000039 2 2 Tosto G Polygenic risk scores in familial Alzheimer disease. Neurology 17/02/2017 10.1212/WNL.0000000000003734 28213371
PGP000038 0 1 Patel KA Type 1 Diabetes Genetic Risk Score: A Novel Tool to Discriminate Monogenic and Type 1 Diabetes. Diabetes 05/04/2016 10.2337/db15-1690 27207547
PGP000037 1 1 Lakeman IMM Addition of a 161-SNP polygenic risk score to family history-based risk prediction: impact on clinical management in non-BRCA1/2 breast cancer families. J Med Genet 11/06/2019 10.1136/jmedgenet-2019-106072 31186341
PGP000036 1 1 Zhang X Addition of a polygenic risk score, mammographic density, and endogenous hormones to existing breast cancer risk prediction models: A nested case-control study. PLoS Med 04/09/2018 10.1371/journal.pmed.1002644 30180161
PGP000035 1 1 Wen W Prediction of breast cancer risk based on common genetic variants in women of East Asian ancestry. Breast Cancer Res 08/12/2016 10.1186/s13058-016-0786-1 27931260
PGP000034 1 4 Lecarpentier J Prediction of Breast and Prostate Cancer Risks in Male BRCA1 and BRCA2 Mutation Carriers Using Polygenic Risk Scores. J Clin Oncol 27/04/2017 10.1200/JCO.2016.69.4935 28448241
PGP000033 4 7 Kuchenbaecker KB Evaluation of Polygenic Risk Scores for Breast and Ovarian Cancer Risk Prediction in BRCA1 and BRCA2 Mutation Carriers. J Natl Cancer Inst 01/07/2017 10.1093/jnci/djw302 28376175
PGP000032 0 1 Pashayan N Implications of polygenic risk-stratified screening for prostate cancer on overdiagnosis. Genet Med 08/01/2015 10.1038/gim.2014.192 25569441
PGP000031 1 1 Pashayan N Reducing overdiagnosis by polygenic risk-stratified screening: findings from the Finnish section of the ERSPC. Br J Cancer 20/08/2015 10.1038/bjc.2015.289 26291059
PGP000030 1 1 Klarin D Genome-wide association analysis of venous thromboembolism identifies new risk loci and genetic overlap with arterial vascular disease. Nat Genet 01/11/2019 10.1038/s41588-019-0519-3 31676865
PGP000029 2 3 Abraham G Genomic prediction of celiac disease targeting HLA-positive individuals. Genome Med 16/07/2015 10.1186/s13073-015-0196-5 26244058
PGP000028 1 1 Abraham G Accurate and robust genomic prediction of celiac disease using statistical learning. PLoS Genet 13/02/2014 10.1371/journal.pgen.1004137 24550740
PGP000027 1 2 Abraham G Genomic risk score offers predictive performance comparable to clinical risk factors for ischaemic stroke. Nat Commun 20/12/2019 10.1038/s41467-019-13848-1 31862893
PGP000026 1 1 Rutten-Jacobs LC Genetic risk, incident stroke, and the benefits of adhering to a healthy lifestyle: cohort study of 306 473 UK Biobank participants. BMJ 24/10/2018 10.1136/bmj.k4168 30355576
PGP000025 1 1 Belsky DW Polygenic risk and the development and course of asthma: an analysis of data from a four-decade longitudinal study. Lancet Respir Med 28/06/2013 10.1016/S2213-2600(13)70101-2 24429243
PGP000024 0 1 Udler MS Genetic Risk Scores for Diabetes Diagnosis and Precision Medicine. Endocr Rev 01/12/2019 10.1210/er.2019-00088 31322649
PGP000023 1 0 Mahajan A Fine-mapping type 2 diabetes loci to single-variant resolution using high-density imputation and islet-specific epigenome maps. Nat Genet 08/10/2018 10.1038/s41588-018-0241-6 30297969
PGP000022 1 1 Weng LC Genetic Predisposition, Clinical Risk Factor Burden, and Lifetime Risk of Atrial Fibrillation. Circulation 12/11/2017 10.1161/CIRCULATIONAHA.117.031431 29129827
PGP000021 1 1 Song M Longitudinal Analysis of Genetic Susceptibility and BMI Throughout Adult Life. Diabetes 06/12/2017 10.2337/db17-1156 29212779
PGP000020 3 3 Vassy JL Polygenic type 2 diabetes prediction at the limit of common variant detection. Diabetes 11/02/2014 10.2337/db13-1663 24520119
PGP000019 1 1 Schumacher FR Association analyses of more than 140,000 men identify 63 new prostate cancer susceptibility loci. Nat Genet 11/06/2018 10.1038/s41588-018-0142-8 29892016
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