PGS Publication: PGP000118

Publication Information (EuropePMC)
Title Cancer PRSweb: An Online Repository with Polygenic Risk Scores for Major Cancer Traits and Their Evaluation in Two Independent Biobanks.
PubMed ID 32991828(Europe PMC)
doi 10.1016/j.ajhg.2020.08.025
Publication Date Sept. 28, 2020
Journal Am J Hum Genet
Author(s) Fritsche LG, Patil S, Beesley LJ, VandeHaar P, Salvatore M, Ma Y, Peng RB, Taliun D, Zhou X, Mukherjee B.
Released in PGS Catalog: Dec. 15, 2020

Associated Polygenic Score(s)

PGS Developed By This Publication

Polygenic Score (PGS) ID PGS Name PGS Publication (PGP) ID Reported Trait Mapped Trait(s) (Ontology) Number of Variants PGS Scoring File (FTP Link)
PGS000403 PRSWEB_PHECODE172_C3-SKIN_LASSOSUM_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Skin cancer skin carcinoma 16,316 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000403/ScoringFiles/PGS000403.txt.gz
PGS000355 PRSWEB_PHECODE10001_UKBB-SAIGE-HRC-X10001_PT_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Any Cancer cancer 15 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000355/ScoringFiles/PGS000355.txt.gz
PGS000357 PRSWEB_PHECODE145_C3-LIP-ORAL-PHARYNX_PT_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Cancer of mouth oral cavity cancer 45 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000357/ScoringFiles/PGS000357.txt.gz
PGS000479 PRSWEB_PHECODE174.1_C3-BREAST-3_LASSOSUM_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Breast cancer (female) breast carcinoma 2,267 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000479/ScoringFiles/PGS000479.txt.gz
PGS000376 PRSWEB_PHECODE153.2_C18_PRS-CS_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Colon cancer colon carcinoma 1,111,490 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000376/ScoringFiles/PGS000376.txt.gz
PGS000358 PRSWEB_PHECODE145_UKBB-SAIGE-HRC-X145_PRS-CS_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Cancer of mouth oral cavity cancer 1,119,238 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000358/ScoringFiles/PGS000358.txt.gz
PGS000476 PRSWEB_PHECODE174.1_C3-BREAST-3_P_5e-08_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Breast cancer (female) breast carcinoma 32 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000476/ScoringFiles/PGS000476.txt.gz
PGS000365 PRSWEB_PHECODE150_C3-OESOPHAGUS_PRS-CS_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Cancer of esophagus esophageal cancer 1,070,434 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000365/ScoringFiles/PGS000365.txt.gz
PGS000359 PRSWEB_PHECODE145.2_C3-TONGUENAS_PRS-CS_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Cancer of tongue tongue neoplasm 931,954 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000359/ScoringFiles/PGS000359.txt.gz
PGS000360 PRSWEB_PHECODE149.4_C32_LASSOSUM_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Cancer of larynx larynx cancer 25,920 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000360/ScoringFiles/PGS000360.txt.gz
PGS000361 PRSWEB_PHECODE149.4_C3-LARYNX_LASSOSUM_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Cancer of larynx larynx cancer 87,893 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000361/ScoringFiles/PGS000361.txt.gz
PGS000362 PRSWEB_PHECODE149.4_UKBB-SAIGE-HRC-X149.4_PT_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Cancer of larynx larynx cancer 53 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000362/ScoringFiles/PGS000362.txt.gz
PGS000363 PRSWEB_PHECODE150_C15_PRS-CS_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Cancer of esophagus esophageal cancer 1,081,646 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000363/ScoringFiles/PGS000363.txt.gz
PGS000364 PRSWEB_PHECODE150_C15_LASSOSUM_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Cancer of esophagus esophageal cancer 2,001 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000364/ScoringFiles/PGS000364.txt.gz
PGS000366 PRSWEB_PHECODE150_UKBB-SAIGE-HRC-X150_PRS-CS_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Cancer of esophagus esophageal cancer 1,119,238 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000366/ScoringFiles/PGS000366.txt.gz
PGS000367 PRSWEB_PHECODE153_CRC-Huyghe_P_5e-08_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Colorectal cancer colorectal cancer 74 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000367/ScoringFiles/PGS000367.txt.gz
PGS000368 PRSWEB_PHECODE153_CRC-Huyghe_P_5e-08_UKB_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Colorectal cancer colorectal cancer 74 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000368/ScoringFiles/PGS000368.txt.gz
PGS000369 PRSWEB_PHECODE153_CRC-Huyghe_PT_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Colorectal cancer colorectal cancer 81 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000369/ScoringFiles/PGS000369.txt.gz
PGS000370 PRSWEB_PHECODE153_CRC-Huyghe_PT_UKB_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Colorectal cancer colorectal cancer 87 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000370/ScoringFiles/PGS000370.txt.gz
PGS000371 PRSWEB_PHECODE153_GWAS-Catalog-r2019-05-03-X153_P_5e-08_UKB_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Colorectal cancer colorectal cancer 18 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000371/ScoringFiles/PGS000371.txt.gz
PGS000372 PRSWEB_PHECODE153_GWAS-Catalog-r2019-05-03-X153_PT_UKB_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Colorectal cancer colorectal cancer 27 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000372/ScoringFiles/PGS000372.txt.gz
PGS000373 PRSWEB_PHECODE153_UKBB-SAIGE-HRC-X153_PRS-CS_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Colorectal cancer colorectal cancer 1,119,238 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000373/ScoringFiles/PGS000373.txt.gz
PGS000374 PRSWEB_PHECODE153_UKBB-SAIGE-HRC-X153_PT_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Colorectal cancer colorectal cancer 41 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000374/ScoringFiles/PGS000374.txt.gz
PGS000375 PRSWEB_PHECODE153_UKBB-SAIGE-HRC-X153_LASSOSUM_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Colorectal cancer colorectal cancer 370 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000375/ScoringFiles/PGS000375.txt.gz
PGS000377 PRSWEB_PHECODE153.2_C18_LASSOSUM_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Colon cancer colon carcinoma 5,740,814 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000377/ScoringFiles/PGS000377.txt.gz
PGS000378 PRSWEB_PHECODE153.2_C3-COLON_PRS-CS_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Colon cancer colon carcinoma 1,111,399 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000378/ScoringFiles/PGS000378.txt.gz
PGS000379 PRSWEB_PHECODE153.2_C3-COLON_LASSOSUM_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Colon cancer colon carcinoma 5,715,093 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000379/ScoringFiles/PGS000379.txt.gz
PGS000380 PRSWEB_PHECODE153.2_UKBB-SAIGE-HRC-X153.2_PRS-CS_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Colon cancer colon carcinoma 1,119,238 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000380/ScoringFiles/PGS000380.txt.gz
PGS000381 PRSWEB_PHECODE153.2_UKBB-SAIGE-HRC-X153.2_PT_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Colon cancer colon carcinoma 12 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000381/ScoringFiles/PGS000381.txt.gz
PGS000382 PRSWEB_PHECODE153.2_UKBB-SAIGE-HRC-X153.2_LASSOSUM_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Colon cancer colon carcinoma 150 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000382/ScoringFiles/PGS000382.txt.gz
PGS000383 PRSWEB_PHECODE153.3_C19_PRS-CS_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Malignant neoplasm of rectum, rectosigmoid junction, and anus rectum cancer
rectosigmoid junction neoplasm
1,078,799 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000383/ScoringFiles/PGS000383.txt.gz
PGS000384 PRSWEB_PHECODE153.3_C3-RECTUM_PRS-CS_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Malignant neoplasm of rectum, rectosigmoid junction, and anus rectum cancer
rectosigmoid junction neoplasm
1,104,018 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000384/ScoringFiles/PGS000384.txt.gz
PGS000385 PRSWEB_PHECODE157_GWAS-Catalog-r2019-05-03-X157_P_5e-08_UKB_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Pancreatic cancer pancreatic carcinoma 17 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000385/ScoringFiles/PGS000385.txt.gz
PGS000386 PRSWEB_PHECODE157_GWAS-Catalog-r2019-05-03-X157_PT_UKB_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Pancreatic cancer pancreatic carcinoma 10 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000386/ScoringFiles/PGS000386.txt.gz
PGS000387 PRSWEB_PHECODE165_UKBB-SAIGE-HRC-X165_LASSOSUM_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Cancer within the respiratory system respiratory system cancer 879,334 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000387/ScoringFiles/PGS000387.txt.gz
PGS000388 PRSWEB_PHECODE165.1_C3-BRONCHUS-LUNG_PRS-CS_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Cancer of bronchus; lung bronchus cancer
lung cancer
tracheal cancer
1,109,069 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000388/ScoringFiles/PGS000388.txt.gz
PGS000389 PRSWEB_PHECODE165.1_GWAS-Catalog-r2019-05-03-X165.1_P_5e-08_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Cancer of bronchus; lung bronchus cancer
lung cancer
tracheal cancer
21 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000389/ScoringFiles/PGS000389.txt.gz
PGS000390 PRSWEB_PHECODE165.1_GWAS-Catalog-r2019-05-03-X165.1_P_5e-08_UKB_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Cancer of bronchus; lung bronchus cancer
lung cancer
tracheal cancer
21 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000390/ScoringFiles/PGS000390.txt.gz
PGS000391 PRSWEB_PHECODE165.1_GWAS-Catalog-r2019-05-03-X165.1_PT_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Cancer of bronchus; lung bronchus cancer
lung cancer
tracheal cancer
14 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000391/ScoringFiles/PGS000391.txt.gz
PGS000392 PRSWEB_PHECODE165.1_GWAS-Catalog-r2019-05-03-X165.1_PT_UKB_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Cancer of bronchus; lung bronchus cancer
lung cancer
tracheal cancer
19 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000392/ScoringFiles/PGS000392.txt.gz
PGS000393 PRSWEB_PHECODE165.1_LUNG-CANCER_PRS-CS_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Cancer of bronchus; lung bronchus cancer
lung cancer
tracheal cancer
1,110,438 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000393/ScoringFiles/PGS000393.txt.gz
PGS000394 PRSWEB_PHECODE165.1_LUNG-CANCER-MESOT_PRS-CS_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Cancer of bronchus; lung bronchus cancer
lung cancer
tracheal cancer
1,110,438 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000394/ScoringFiles/PGS000394.txt.gz
PGS000395 PRSWEB_PHECODE165.1_UKBB-SAIGE-HRC-X165.1_PRS-CS_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Cancer of bronchus; lung bronchus cancer
lung cancer
tracheal cancer
1,119,238 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000395/ScoringFiles/PGS000395.txt.gz
PGS000396 PRSWEB_PHECODE165.1_UKBB-SAIGE-HRC-X165.1_PT_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Cancer of bronchus; lung bronchus cancer
lung cancer
tracheal cancer
75 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000396/ScoringFiles/PGS000396.txt.gz
PGS000397 PRSWEB_PHECODE165.1_UKBB-SAIGE-HRC-X165.1_LASSOSUM_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Cancer of bronchus; lung bronchus cancer
lung cancer
tracheal cancer
46,920 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000397/ScoringFiles/PGS000397.txt.gz
PGS000398 PRSWEB_PHECODE172_20001-1003_PRS-CS_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Skin cancer skin carcinoma 1,103,220 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000398/ScoringFiles/PGS000398.txt.gz
PGS000399 PRSWEB_PHECODE172_20001-1003_PT_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Skin cancer skin carcinoma 6 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000399/ScoringFiles/PGS000399.txt.gz
PGS000400 PRSWEB_PHECODE172_C3-SKIN_P_5e-08_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Skin cancer skin carcinoma 95 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000400/ScoringFiles/PGS000400.txt.gz
PGS000401 PRSWEB_PHECODE172_C3-SKIN_PRS-CS_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Skin cancer skin carcinoma 1,111,490 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000401/ScoringFiles/PGS000401.txt.gz
PGS000402 PRSWEB_PHECODE172_C3-SKIN_PT_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Skin cancer skin carcinoma 389 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000402/ScoringFiles/PGS000402.txt.gz
PGS000404 PRSWEB_PHECODE172_UKBB-SAIGE-HRC-X172_P_5e-08_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Skin cancer skin carcinoma 80 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000404/ScoringFiles/PGS000404.txt.gz
PGS000405 PRSWEB_PHECODE172_UKBB-SAIGE-HRC-X172_PRS-CS_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Skin cancer skin carcinoma 1,119,238 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000405/ScoringFiles/PGS000405.txt.gz
PGS000406 PRSWEB_PHECODE172_UKBB-SAIGE-HRC-X172_PT_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Skin cancer skin carcinoma 292 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000406/ScoringFiles/PGS000406.txt.gz
PGS000407 PRSWEB_PHECODE172_UKBB-SAIGE-HRC-X172_LASSOSUM_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Skin cancer skin carcinoma 3,166 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000407/ScoringFiles/PGS000407.txt.gz
PGS000408 PRSWEB_PHECODE172.1_20001-1059_P_5e-08_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Melanomas of skin (diagnosis or history) melanoma 10 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000408/ScoringFiles/PGS000408.txt.gz
PGS000409 PRSWEB_PHECODE172.1_20001-1059_PRS-CS_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Melanomas of skin (diagnosis or history) melanoma 1,111,490 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000409/ScoringFiles/PGS000409.txt.gz
PGS000410 PRSWEB_PHECODE172.1_20001-1059_PT_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Melanomas of skin (diagnosis or history) melanoma 7 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000410/ScoringFiles/PGS000410.txt.gz
PGS000411 PRSWEB_PHECODE172.1_20001-1059_LASSOSUM_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Melanomas of skin (diagnosis or history) melanoma 185 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000411/ScoringFiles/PGS000411.txt.gz
PGS000412 PRSWEB_PHECODE172.1_C3-MELANOMA-SKIN_P_5e-08_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Melanomas of skin (diagnosis or history) melanoma 16 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000412/ScoringFiles/PGS000412.txt.gz
PGS000413 PRSWEB_PHECODE172.1_C3-MELANOMA-SKIN_PRS-CS_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Melanomas of skin (diagnosis or history) melanoma 1,111,490 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000413/ScoringFiles/PGS000413.txt.gz
PGS000414 PRSWEB_PHECODE172.1_C3-MELANOMA-SKIN_PT_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Melanomas of skin (diagnosis or history) melanoma 21 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000414/ScoringFiles/PGS000414.txt.gz
PGS000415 PRSWEB_PHECODE172.1_C3-MELANOMA-SKIN_LASSOSUM_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Melanomas of skin (diagnosis or history) melanoma 505 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000415/ScoringFiles/PGS000415.txt.gz
PGS000416 PRSWEB_PHECODE172.1_C43_P_5e-08_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Melanomas of skin (diagnosis or history) melanoma 9 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000416/ScoringFiles/PGS000416.txt.gz
PGS000417 PRSWEB_PHECODE172.1_C43_PRS-CS_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Melanomas of skin (diagnosis or history) melanoma 1,109,519 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000417/ScoringFiles/PGS000417.txt.gz
PGS000418 PRSWEB_PHECODE172.1_C43_PT_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Melanomas of skin (diagnosis or history) melanoma 9 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000418/ScoringFiles/PGS000418.txt.gz
PGS000419 PRSWEB_PHECODE172.1_C43_LASSOSUM_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Melanomas of skin (diagnosis or history) melanoma 436 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000419/ScoringFiles/PGS000419.txt.gz
PGS000420 PRSWEB_PHECODE172.1_D03_PT_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Melanomas of skin (diagnosis or history) melanoma 147 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000420/ScoringFiles/PGS000420.txt.gz
PGS000421 PRSWEB_PHECODE172.1_GWAS-Catalog-r2019-05-03-X172.1_P_5e-08_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Melanomas of skin (diagnosis or history) melanoma 18 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000421/ScoringFiles/PGS000421.txt.gz
PGS000422 PRSWEB_PHECODE172.1_GWAS-Catalog-r2019-05-03-X172.1_P_5e-08_UKB_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Melanomas of skin (diagnosis or history) melanoma 18 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000422/ScoringFiles/PGS000422.txt.gz
PGS000423 PRSWEB_PHECODE172.1_GWAS-Catalog-r2019-05-03-X172.1_PT_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Melanomas of skin (diagnosis or history) melanoma 29 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000423/ScoringFiles/PGS000423.txt.gz
PGS000424 PRSWEB_PHECODE172.1_GWAS-Catalog-r2019-05-03-X172.1_PT_UKB_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Melanomas of skin (diagnosis or history) melanoma 27 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000424/ScoringFiles/PGS000424.txt.gz
PGS000425 PRSWEB_PHECODE172.1_Melanoma-Ransohoff_P_5e-08_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Melanomas of skin (diagnosis or history) melanoma 20 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000425/ScoringFiles/PGS000425.txt.gz
PGS000426 PRSWEB_PHECODE172.1_Melanoma-Ransohoff_P_5e-08_UKB_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Melanomas of skin (diagnosis or history) melanoma 20 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000426/ScoringFiles/PGS000426.txt.gz
PGS000427 PRSWEB_PHECODE172.1_Melanoma-Ransohoff_PT_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Melanomas of skin (diagnosis or history) melanoma 20 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000427/ScoringFiles/PGS000427.txt.gz
PGS000428 PRSWEB_PHECODE172.1_Melanoma-Ransohoff_PT_UKB_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Melanomas of skin (diagnosis or history) melanoma 20 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000428/ScoringFiles/PGS000428.txt.gz
PGS000429 PRSWEB_PHECODE172.1_UKBB-SAIGE-HRC-X172.1_P_5e-08_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Melanomas of skin (diagnosis or history) melanoma 12 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000429/ScoringFiles/PGS000429.txt.gz
PGS000430 PRSWEB_PHECODE172.1_UKBB-SAIGE-HRC-X172.1_PRS-CS_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Melanomas of skin (diagnosis or history) melanoma 1,119,238 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000430/ScoringFiles/PGS000430.txt.gz
PGS000431 PRSWEB_PHECODE172.1_UKBB-SAIGE-HRC-X172.1_PT_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Melanomas of skin (diagnosis or history) melanoma 15 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000431/ScoringFiles/PGS000431.txt.gz
PGS000432 PRSWEB_PHECODE172.1_UKBB-SAIGE-HRC-X172.1_LASSOSUM_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Melanomas of skin (diagnosis or history) melanoma 296 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000432/ScoringFiles/PGS000432.txt.gz
PGS000433 PRSWEB_PHECODE172.2_C3-OTHER-SKIN_P_5e-08_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Other non-epithelial cancer of skin skin cancer 108 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000433/ScoringFiles/PGS000433.txt.gz
PGS000434 PRSWEB_PHECODE172.2_C3-OTHER-SKIN_PRS-CS_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Other non-epithelial cancer of skin skin cancer 1,111,490 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000434/ScoringFiles/PGS000434.txt.gz
PGS000435 PRSWEB_PHECODE172.2_C3-OTHER-SKIN_PT_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Other non-epithelial cancer of skin skin cancer 446 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000435/ScoringFiles/PGS000435.txt.gz
PGS000436 PRSWEB_PHECODE172.2_C3-OTHER-SKIN_LASSOSUM_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Other non-epithelial cancer of skin skin cancer 16,626 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000436/ScoringFiles/PGS000436.txt.gz
PGS000437 PRSWEB_PHECODE172.2_C44_P_5e-08_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Other non-epithelial cancer of skin skin cancer 63 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000437/ScoringFiles/PGS000437.txt.gz
PGS000438 PRSWEB_PHECODE172.2_C44_PRS-CS_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Other non-epithelial cancer of skin skin cancer 1,111,490 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000438/ScoringFiles/PGS000438.txt.gz
PGS000439 PRSWEB_PHECODE172.2_C44_PT_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Other non-epithelial cancer of skin skin cancer 467 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000439/ScoringFiles/PGS000439.txt.gz
PGS000440 PRSWEB_PHECODE172.2_C44_LASSOSUM_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Other non-epithelial cancer of skin skin cancer 2,111 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000440/ScoringFiles/PGS000440.txt.gz
PGS000441 PRSWEB_PHECODE172.2_UKBB-SAIGE-HRC-X172.2_P_5e-08_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Other non-epithelial cancer of skin skin cancer 77 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000441/ScoringFiles/PGS000441.txt.gz
PGS000442 PRSWEB_PHECODE172.2_UKBB-SAIGE-HRC-X172.2_PRS-CS_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Other non-epithelial cancer of skin skin cancer 1,119,238 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000442/ScoringFiles/PGS000442.txt.gz
PGS000443 PRSWEB_PHECODE172.2_UKBB-SAIGE-HRC-X172.2_PT_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Other non-epithelial cancer of skin skin cancer 177 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000443/ScoringFiles/PGS000443.txt.gz
PGS000444 PRSWEB_PHECODE172.2_UKBB-SAIGE-HRC-X172.2_LASSOSUM_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Other non-epithelial cancer of skin skin cancer 7,231 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000444/ScoringFiles/PGS000444.txt.gz
PGS000445 PRSWEB_PHECODE172.21_20001-1061_P_5e-08_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Basal cell carcinoma basal cell carcinoma 19 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000445/ScoringFiles/PGS000445.txt.gz
PGS000446 PRSWEB_PHECODE172.21_20001-1061_PRS-CS_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Basal cell carcinoma basal cell carcinoma 1,111,490 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000446/ScoringFiles/PGS000446.txt.gz
PGS000636 PRSWEB_PHECODE193_UKBB-SAIGE-HRC-X193_LASSOSUM_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Thyroid cancer thyroid carcinoma 954 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000636/ScoringFiles/PGS000636.txt.gz
PGS000448 PRSWEB_PHECODE172.21_20001-1061_LASSOSUM_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Basal cell carcinoma basal cell carcinoma 183 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000448/ScoringFiles/PGS000448.txt.gz
PGS000449 PRSWEB_PHECODE172.21_20001-1073_PRS-CS_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Basal cell carcinoma basal cell carcinoma 1,073,162 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000449/ScoringFiles/PGS000449.txt.gz
PGS000450 PRSWEB_PHECODE172.21_20001-1073_PT_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Basal cell carcinoma basal cell carcinoma 8 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000450/ScoringFiles/PGS000450.txt.gz
PGS000451 PRSWEB_PHECODE172.21_20001-1073_LASSOSUM_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Basal cell carcinoma basal cell carcinoma 2,231 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000451/ScoringFiles/PGS000451.txt.gz
PGS000452 PRSWEB_PHECODE172.21_BCC-Chahal_P_5e-08_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Basal cell carcinoma basal cell carcinoma 28 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000452/ScoringFiles/PGS000452.txt.gz
PGS000453 PRSWEB_PHECODE172.21_BCC-Chahal_P_5e-08_UKB_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Basal cell carcinoma basal cell carcinoma 28 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000453/ScoringFiles/PGS000453.txt.gz
PGS000454 PRSWEB_PHECODE172.21_BCC-Chahal_PT_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Basal cell carcinoma basal cell carcinoma 27 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000454/ScoringFiles/PGS000454.txt.gz
PGS000455 PRSWEB_PHECODE172.21_BCC-Chahal_PT_UKB_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Basal cell carcinoma basal cell carcinoma 28 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000455/ScoringFiles/PGS000455.txt.gz
PGS000456 PRSWEB_PHECODE172.21_GWAS-Catalog-r2019-05-03-X172.21_P_5e-08_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Basal cell carcinoma basal cell carcinoma 30 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000456/ScoringFiles/PGS000456.txt.gz
PGS000457 PRSWEB_PHECODE172.21_GWAS-Catalog-r2019-05-03-X172.21_P_5e-08_UKB_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Basal cell carcinoma basal cell carcinoma 30 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000457/ScoringFiles/PGS000457.txt.gz
PGS000458 PRSWEB_PHECODE172.21_GWAS-Catalog-r2019-05-03-X172.21_PT_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Basal cell carcinoma basal cell carcinoma 23 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000458/ScoringFiles/PGS000458.txt.gz
PGS000459 PRSWEB_PHECODE172.21_GWAS-Catalog-r2019-05-03-X172.21_PT_UKB_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Basal cell carcinoma basal cell carcinoma 24 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000459/ScoringFiles/PGS000459.txt.gz
PGS000460 PRSWEB_PHECODE172.22_20001-1062_LASSOSUM_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Squamous cell carcinoma squamous cell carcinoma 4,279,140 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000460/ScoringFiles/PGS000460.txt.gz
PGS000461 PRSWEB_PHECODE172.22_GWAS-Catalog-r2019-05-03-X172.22_P_5e-08_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Squamous cell carcinoma squamous cell carcinoma 13 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000461/ScoringFiles/PGS000461.txt.gz
PGS000462 PRSWEB_PHECODE172.22_GWAS-Catalog-r2019-05-03-X172.22_P_5e-08_UKB_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Squamous cell carcinoma squamous cell carcinoma 13 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000462/ScoringFiles/PGS000462.txt.gz
PGS000464 PRSWEB_PHECODE172.22_GWAS-Catalog-r2019-05-03-X172.22_PT_UKB_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Squamous cell carcinoma squamous cell carcinoma 14 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000464/ScoringFiles/PGS000464.txt.gz
PGS000465 PRSWEB_PHECODE172.22_cSCC-Chahal_P_5e-08_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Squamous cell carcinoma squamous cell carcinoma 10 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000465/ScoringFiles/PGS000465.txt.gz
PGS000466 PRSWEB_PHECODE172.22_cSCC-Chahal_P_5e-08_UKB_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Squamous cell carcinoma squamous cell carcinoma 10 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000466/ScoringFiles/PGS000466.txt.gz
PGS000467 PRSWEB_PHECODE172.22_cSCC-Chahal_PT_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Squamous cell carcinoma squamous cell carcinoma 6 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000467/ScoringFiles/PGS000467.txt.gz
PGS000468 PRSWEB_PHECODE172.22_cSCC-Chahal_PT_UKB_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Squamous cell carcinoma squamous cell carcinoma 9 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000468/ScoringFiles/PGS000468.txt.gz
PGS000469 PRSWEB_PHECODE172.3_UKBB-SAIGE-HRC-X172.3_PRS-CS_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Carcinoma in situ of skin skin carcinoma in situ 1,119,238 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000469/ScoringFiles/PGS000469.txt.gz
PGS000470 PRSWEB_PHECODE172.3_UKBB-SAIGE-HRC-X172.3_PT_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Carcinoma in situ of skin skin carcinoma in situ 5 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000470/ScoringFiles/PGS000470.txt.gz
PGS000471 PRSWEB_PHECODE172.3_UKBB-SAIGE-HRC-X172.3_LASSOSUM_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Carcinoma in situ of skin skin carcinoma in situ 7 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000471/ScoringFiles/PGS000471.txt.gz
PGS000472 PRSWEB_PHECODE174.1_20001-1002_P_5e-08_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Breast cancer (female) breast carcinoma 22 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000472/ScoringFiles/PGS000472.txt.gz
PGS000473 PRSWEB_PHECODE174.1_20001-1002_PRS-CS_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Breast cancer (female) breast carcinoma 1,111,495 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000473/ScoringFiles/PGS000473.txt.gz
PGS000480 PRSWEB_PHECODE174.1_C50_P_5e-08_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Breast cancer (female) breast carcinoma 20 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000480/ScoringFiles/PGS000480.txt.gz
PGS000481 PRSWEB_PHECODE174.1_C50_PRS-CS_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Breast cancer (female) breast carcinoma 1,111,495 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000481/ScoringFiles/PGS000481.txt.gz
PGS000482 PRSWEB_PHECODE174.1_C50_PT_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Breast cancer (female) breast carcinoma 42 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000482/ScoringFiles/PGS000482.txt.gz
PGS000483 PRSWEB_PHECODE174.1_C50_LASSOSUM_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Breast cancer (female) breast carcinoma 4,047 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000483/ScoringFiles/PGS000483.txt.gz
PGS000484 PRSWEB_PHECODE174.1_D05_PT_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Breast cancer (female) breast carcinoma 25 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000484/ScoringFiles/PGS000484.txt.gz
PGS000503 PRSWEB_PHECODE174.1_Onco-iCOGS-ER-positive-BRCA_LASSOSUM_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Breast cancer (female) breast carcinoma 61,635 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000503/ScoringFiles/PGS000503.txt.gz
PGS000485 PRSWEB_PHECODE174.1_GWAS-Catalog-r2019-05-03-X174.1_P_5e-08_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Breast cancer (female) breast carcinoma 62 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000485/ScoringFiles/PGS000485.txt.gz
PGS000487 PRSWEB_PHECODE174.1_GWAS-Catalog-r2019-05-03-X174.1_PT_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Breast cancer (female) breast carcinoma 62 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000487/ScoringFiles/PGS000487.txt.gz
PGS000488 PRSWEB_PHECODE174.1_GWAS-Catalog-r2019-05-03-X174.1_PT_UKB_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Breast cancer (female) breast carcinoma 79 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000488/ScoringFiles/PGS000488.txt.gz
PGS000489 PRSWEB_PHECODE174.1_Onco-iCOGS-ER-negative-BRCA_P_5e-08_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Breast cancer (female) breast carcinoma 49 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000489/ScoringFiles/PGS000489.txt.gz
PGS000490 PRSWEB_PHECODE174.1_Onco-iCOGS-ER-negative-BRCA_P_5e-08_UKB_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Breast cancer (female) breast carcinoma 49 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000490/ScoringFiles/PGS000490.txt.gz
PGS000491 PRSWEB_PHECODE174.1_Onco-iCOGS-ER-negative-BRCA_PRS-CS_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Breast cancer (female) breast carcinoma 1,119,140 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000491/ScoringFiles/PGS000491.txt.gz
PGS000492 PRSWEB_PHECODE174.1_Onco-iCOGS-ER-negative-BRCA_PRS-CS_UKB_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Breast cancer (female) breast carcinoma 1,120,410 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000492/ScoringFiles/PGS000492.txt.gz
PGS000493 PRSWEB_PHECODE174.1_Onco-iCOGS-ER-negative-BRCA_PT_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Breast cancer (female) breast carcinoma 217 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000493/ScoringFiles/PGS000493.txt.gz
PGS000494 PRSWEB_PHECODE174.1_Onco-iCOGS-ER-negative-BRCA_PT_UKB_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Breast cancer (female) breast carcinoma 49 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000494/ScoringFiles/PGS000494.txt.gz
PGS000495 PRSWEB_PHECODE174.1_Onco-iCOGS-ER-negative-BRCA_LASSOSUM_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Breast cancer (female) breast carcinoma 18,866 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000495/ScoringFiles/PGS000495.txt.gz
PGS000496 PRSWEB_PHECODE174.1_Onco-iCOGS-ER-negative-BRCA_LASSOSUM_UKB_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Breast cancer (female) breast carcinoma 41,744 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000496/ScoringFiles/PGS000496.txt.gz
PGS000497 PRSWEB_PHECODE174.1_Onco-iCOGS-ER-positive-BRCA_P_5e-08_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Breast cancer (female) breast carcinoma 257 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000497/ScoringFiles/PGS000497.txt.gz
PGS000498 PRSWEB_PHECODE174.1_Onco-iCOGS-ER-positive-BRCA_P_5e-08_UKB_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Breast cancer (female) breast carcinoma 257 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000498/ScoringFiles/PGS000498.txt.gz
PGS000499 PRSWEB_PHECODE174.1_Onco-iCOGS-ER-positive-BRCA_PRS-CS_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Breast cancer (female) breast carcinoma 1,119,140 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000499/ScoringFiles/PGS000499.txt.gz
PGS000500 PRSWEB_PHECODE174.1_Onco-iCOGS-ER-positive-BRCA_PRS-CS_UKB_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Breast cancer (female) breast carcinoma 1,120,410 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000500/ScoringFiles/PGS000500.txt.gz
PGS000501 PRSWEB_PHECODE174.1_Onco-iCOGS-ER-positive-BRCA_PT_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Breast cancer (female) breast carcinoma 1,142 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000501/ScoringFiles/PGS000501.txt.gz
PGS000502 PRSWEB_PHECODE174.1_Onco-iCOGS-ER-positive-BRCA_PT_UKB_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Breast cancer (female) breast carcinoma 747 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000502/ScoringFiles/PGS000502.txt.gz
PGS000504 PRSWEB_PHECODE174.1_Onco-iCOGS-ER-positive-BRCA_LASSOSUM_UKB_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Breast cancer (female) breast carcinoma 148,560 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000504/ScoringFiles/PGS000504.txt.gz
PGS000505 PRSWEB_PHECODE174.1_Onco-iCOGS-Overall-BRCA_P_5e-08_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Breast cancer (female) breast carcinoma 334 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000505/ScoringFiles/PGS000505.txt.gz
PGS000506 PRSWEB_PHECODE174.1_Onco-iCOGS-Overall-BRCA_P_5e-08_UKB_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Breast cancer (female) breast carcinoma 334 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000506/ScoringFiles/PGS000506.txt.gz
PGS000507 PRSWEB_PHECODE174.1_Onco-iCOGS-Overall-BRCA_PRS-CS_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Breast cancer (female) breast carcinoma 1,119,140 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000507/ScoringFiles/PGS000507.txt.gz
PGS000508 PRSWEB_PHECODE174.1_Onco-iCOGS-Overall-BRCA_PRS-CS_UKB_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Breast cancer (female) breast carcinoma 1,120,410 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000508/ScoringFiles/PGS000508.txt.gz
PGS000509 PRSWEB_PHECODE174.1_Onco-iCOGS-Overall-BRCA_PT_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Breast cancer (female) breast carcinoma 3,038 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000509/ScoringFiles/PGS000509.txt.gz
PGS000510 PRSWEB_PHECODE174.1_Onco-iCOGS-Overall-BRCA_PT_UKB_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Breast cancer (female) breast carcinoma 1,682 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000510/ScoringFiles/PGS000510.txt.gz
PGS000511 PRSWEB_PHECODE174.1_Onco-iCOGS-Overall-BRCA_LASSOSUM_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Breast cancer (female) breast carcinoma 118,388 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000511/ScoringFiles/PGS000511.txt.gz
PGS000512 PRSWEB_PHECODE174.1_Onco-iCOGS-Overall-BRCA_LASSOSUM_UKB_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Breast cancer (female) breast carcinoma 286,144 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000512/ScoringFiles/PGS000512.txt.gz
PGS000513 PRSWEB_PHECODE174.1_UKBB-SAIGE-HRC-X174.1_P_5e-08_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Breast cancer (female) breast carcinoma 41 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000513/ScoringFiles/PGS000513.txt.gz
PGS000514 PRSWEB_PHECODE174.1_UKBB-SAIGE-HRC-X174.1_PRS-CS_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Breast cancer (female) breast carcinoma 1,119,237 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000514/ScoringFiles/PGS000514.txt.gz
PGS000515 PRSWEB_PHECODE174.1_UKBB-SAIGE-HRC-X174.1_PT_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Breast cancer (female) breast carcinoma 84 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000515/ScoringFiles/PGS000515.txt.gz
PGS000516 PRSWEB_PHECODE174.1_UKBB-SAIGE-HRC-X174.1_LASSOSUM_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Breast cancer (female) breast carcinoma 6,977 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000516/ScoringFiles/PGS000516.txt.gz
PGS000517 PRSWEB_PHECODE174.1_iCOGS-ER-negative-BRCA_P_5e-08_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Breast cancer (female) breast carcinoma 10 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000517/ScoringFiles/PGS000517.txt.gz
PGS000518 PRSWEB_PHECODE174.1_iCOGS-ER-negative-BRCA_P_5e-08_UKB_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Breast cancer (female) breast carcinoma 10 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000518/ScoringFiles/PGS000518.txt.gz
PGS000519 PRSWEB_PHECODE174.1_iCOGS-ER-negative-BRCA_PRS-CS_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Breast cancer (female) breast carcinoma 1,115,376 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000519/ScoringFiles/PGS000519.txt.gz
PGS000520 PRSWEB_PHECODE174.1_iCOGS-ER-negative-BRCA_PRS-CS_UKB_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Breast cancer (female) breast carcinoma 1,116,435 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000520/ScoringFiles/PGS000520.txt.gz
PGS000521 PRSWEB_PHECODE174.1_iCOGS-ER-negative-BRCA_PT_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Breast cancer (female) breast carcinoma 9 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000521/ScoringFiles/PGS000521.txt.gz
PGS000522 PRSWEB_PHECODE174.1_iCOGS-ER-negative-BRCA_PT_UKB_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Breast cancer (female) breast carcinoma 14 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000522/ScoringFiles/PGS000522.txt.gz
PGS000523 PRSWEB_PHECODE174.1_iCOGS-ER-negative-BRCA_LASSOSUM_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Breast cancer (female) breast carcinoma 270 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000523/ScoringFiles/PGS000523.txt.gz
PGS000524 PRSWEB_PHECODE174.1_iCOGS-ER-negative-BRCA_LASSOSUM_UKB_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Breast cancer (female) breast carcinoma 2,708 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000524/ScoringFiles/PGS000524.txt.gz
PGS000525 PRSWEB_PHECODE174.1_iCOGS-ER-positive-BRCA_P_5e-08_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Breast cancer (female) breast carcinoma 86 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000525/ScoringFiles/PGS000525.txt.gz
PGS000526 PRSWEB_PHECODE174.1_iCOGS-ER-positive-BRCA_P_5e-08_UKB_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Breast cancer (female) breast carcinoma 86 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000526/ScoringFiles/PGS000526.txt.gz
PGS000527 PRSWEB_PHECODE174.1_iCOGS-ER-positive-BRCA_PRS-CS_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Breast cancer (female) breast carcinoma 1,115,436 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000527/ScoringFiles/PGS000527.txt.gz
PGS000528 PRSWEB_PHECODE174.1_iCOGS-ER-positive-BRCA_PRS-CS_UKB_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Breast cancer (female) breast carcinoma 1,116,495 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000528/ScoringFiles/PGS000528.txt.gz
PGS000529 PRSWEB_PHECODE174.1_iCOGS-ER-positive-BRCA_PT_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Breast cancer (female) breast carcinoma 310 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000529/ScoringFiles/PGS000529.txt.gz
PGS000530 PRSWEB_PHECODE174.1_iCOGS-ER-positive-BRCA_PT_UKB_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Breast cancer (female) breast carcinoma 174 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000530/ScoringFiles/PGS000530.txt.gz
PGS000531 PRSWEB_PHECODE174.1_iCOGS-ER-positive-BRCA_LASSOSUM_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Breast cancer (female) breast carcinoma 98,026 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000531/ScoringFiles/PGS000531.txt.gz
PGS000532 PRSWEB_PHECODE174.1_iCOGS-ER-positive-BRCA_LASSOSUM_UKB_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Breast cancer (female) breast carcinoma 12,277 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000532/ScoringFiles/PGS000532.txt.gz
PGS000533 PRSWEB_PHECODE174.1_iCOGS-Overall-BRCA_P_5e-08_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Breast cancer (female) breast carcinoma 110 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000533/ScoringFiles/PGS000533.txt.gz
PGS000534 PRSWEB_PHECODE174.1_iCOGS-Overall-BRCA_P_5e-08_UKB_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Breast cancer (female) breast carcinoma 110 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000534/ScoringFiles/PGS000534.txt.gz
PGS000535 PRSWEB_PHECODE174.1_iCOGS-Overall-BRCA_PRS-CS_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Breast cancer (female) breast carcinoma 1,115,484 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000535/ScoringFiles/PGS000535.txt.gz
PGS000536 PRSWEB_PHECODE174.1_iCOGS-Overall-BRCA_PRS-CS_UKB_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Breast cancer (female) breast carcinoma 1,116,546 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000536/ScoringFiles/PGS000536.txt.gz
PGS000537 PRSWEB_PHECODE174.1_iCOGS-Overall-BRCA_PT_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Breast cancer (female) breast carcinoma 363 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000537/ScoringFiles/PGS000537.txt.gz
PGS000538 PRSWEB_PHECODE174.1_iCOGS-Overall-BRCA_PT_UKB_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Breast cancer (female) breast carcinoma 85 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000538/ScoringFiles/PGS000538.txt.gz
PGS000539 PRSWEB_PHECODE174.1_iCOGS-Overall-BRCA_LASSOSUM_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Breast cancer (female) breast carcinoma 18,356 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000539/ScoringFiles/PGS000539.txt.gz
PGS000540 PRSWEB_PHECODE174.1_iCOGS-Overall-BRCA_LASSOSUM_UKB_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Breast cancer (female) breast carcinoma 7,118 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000540/ScoringFiles/PGS000540.txt.gz
PGS000541 PRSWEB_PHECODE182_GWAS-Catalog-r2019-05-03-X182_P_5e-08_UKB_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Malignant neoplasm of uterus uterine cancer 18 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000541/ScoringFiles/PGS000541.txt.gz
PGS000542 PRSWEB_PHECODE182_GWAS-Catalog-r2019-05-03-X182_PT_UKB_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Malignant neoplasm of uterus uterine cancer 20 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000542/ScoringFiles/PGS000542.txt.gz
PGS000543 PRSWEB_PHECODE184_C3-FEMALE-GENITAL_PT_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Cancer of other female genital organs female reproductive organ cancer 8 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000543/ScoringFiles/PGS000543.txt.gz
PGS000544 PRSWEB_PHECODE184.11_GWAS-Catalog-r2019-05-03-X184.11_P_5e-08_UKB_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Malignant neoplasm of ovary ovarian neoplasm 21 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000544/ScoringFiles/PGS000544.txt.gz
PGS000545 PRSWEB_PHECODE184.11_GWAS-Catalog-r2019-05-03-X184.11_PT_UKB_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Malignant neoplasm of ovary ovarian neoplasm 21 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000545/ScoringFiles/PGS000545.txt.gz
PGS000546 PRSWEB_PHECODE184.11_Phelan-ENOC_PRS-CS_UKB_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Malignant neoplasm of ovary ovarian neoplasm 1,115,189 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000546/ScoringFiles/PGS000546.txt.gz
PGS000547 PRSWEB_PHECODE184.11_Phelan-EPOC_P_5e-08_UKB_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Malignant neoplasm of ovary ovarian neoplasm 6 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000547/ScoringFiles/PGS000547.txt.gz
PGS000548 PRSWEB_PHECODE184.11_Phelan-EPOC_LASSOSUM_UKB_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Malignant neoplasm of ovary ovarian neoplasm 1,441 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000548/ScoringFiles/PGS000548.txt.gz
PGS000549 PRSWEB_PHECODE184.11_Phelan-IEOC_P_5e-08_UKB_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Malignant neoplasm of ovary ovarian neoplasm 16 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000549/ScoringFiles/PGS000549.txt.gz
PGS000550 PRSWEB_PHECODE184.11_Phelan-IEOC_PRS-CS_UKB_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Malignant neoplasm of ovary ovarian neoplasm 1,115,189 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000550/ScoringFiles/PGS000550.txt.gz
PGS000551 PRSWEB_PHECODE184.11_Phelan-IEOC_PT_UKB_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Malignant neoplasm of ovary ovarian neoplasm 12 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000551/ScoringFiles/PGS000551.txt.gz
PGS000552 PRSWEB_PHECODE184.11_Phelan-IEOC_LASSOSUM_UKB_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Malignant neoplasm of ovary ovarian neoplasm 41,269 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000552/ScoringFiles/PGS000552.txt.gz
PGS000553 PRSWEB_PHECODE184.11_Phelan-LSASBOC_P_5e-08_UKB_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Malignant neoplasm of ovary ovarian neoplasm 10 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000553/ScoringFiles/PGS000553.txt.gz
PGS000554 PRSWEB_PHECODE184.11_Phelan-LSASBOC_PRS-CS_UKB_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Malignant neoplasm of ovary ovarian neoplasm 1,115,189 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000554/ScoringFiles/PGS000554.txt.gz
PGS000555 PRSWEB_PHECODE184.11_Phelan-LSASBOC_PT_UKB_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Malignant neoplasm of ovary ovarian neoplasm 15 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000555/ScoringFiles/PGS000555.txt.gz
PGS000556 PRSWEB_PHECODE184.11_Phelan-LSASBOC_LASSOSUM_UKB_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Malignant neoplasm of ovary ovarian neoplasm 486,841 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000556/ScoringFiles/PGS000556.txt.gz
PGS000557 PRSWEB_PHECODE184.11_Phelan-OCCC_PRS-CS_UKB_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Malignant neoplasm of ovary ovarian neoplasm 1,115,187 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000557/ScoringFiles/PGS000557.txt.gz
PGS000558 PRSWEB_PHECODE184.11_Phelan-OCCC_LASSOSUM_UKB_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Malignant neoplasm of ovary ovarian neoplasm 1,098,236 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000558/ScoringFiles/PGS000558.txt.gz
PGS000559 PRSWEB_PHECODE184.11_Phelan-SIOC_P_5e-08_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Malignant neoplasm of ovary ovarian neoplasm 21 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000559/ScoringFiles/PGS000559.txt.gz
PGS000560 PRSWEB_PHECODE184.11_Phelan-SIOC_P_5e-08_UKB_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Malignant neoplasm of ovary ovarian neoplasm 21 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000560/ScoringFiles/PGS000560.txt.gz
PGS000561 PRSWEB_PHECODE184.11_Phelan-SIOC_PRS-CS_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Malignant neoplasm of ovary ovarian neoplasm 1,114,056 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000561/ScoringFiles/PGS000561.txt.gz
PGS000562 PRSWEB_PHECODE184.11_Phelan-SIOC_PRS-CS_UKB_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Malignant neoplasm of ovary ovarian neoplasm 1,115,189 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000562/ScoringFiles/PGS000562.txt.gz
PGS000563 PRSWEB_PHECODE184.11_Phelan-SIOC_PT_UKB_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Malignant neoplasm of ovary ovarian neoplasm 12 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000563/ScoringFiles/PGS000563.txt.gz
PGS000564 PRSWEB_PHECODE184.11_Phelan-SIOC_LASSOSUM_UKB_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Malignant neoplasm of ovary ovarian neoplasm 110,710 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000564/ScoringFiles/PGS000564.txt.gz
PGS000565 PRSWEB_PHECODE185_20001-1044_P_5e-08_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Cancer of prostate prostate carcinoma 21 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000565/ScoringFiles/PGS000565.txt.gz
PGS000566 PRSWEB_PHECODE185_20001-1044_PRS-CS_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Cancer of prostate prostate carcinoma 1,111,494 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000566/ScoringFiles/PGS000566.txt.gz
PGS000567 PRSWEB_PHECODE185_20001-1044_PT_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Cancer of prostate prostate carcinoma 78 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000567/ScoringFiles/PGS000567.txt.gz
PGS000568 PRSWEB_PHECODE185_20001-1044_LASSOSUM_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Cancer of prostate prostate carcinoma 1,401 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000568/ScoringFiles/PGS000568.txt.gz
PGS000569 PRSWEB_PHECODE185_C3-PROSTATE_P_5e-08_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Cancer of prostate prostate carcinoma 49 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000569/ScoringFiles/PGS000569.txt.gz
PGS000570 PRSWEB_PHECODE185_C3-PROSTATE_PRS-CS_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Cancer of prostate prostate carcinoma 1,111,493 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000570/ScoringFiles/PGS000570.txt.gz
PGS000571 PRSWEB_PHECODE185_C3-PROSTATE_PT_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Cancer of prostate prostate carcinoma 100 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000571/ScoringFiles/PGS000571.txt.gz
PGS000572 PRSWEB_PHECODE185_C3-PROSTATE_LASSOSUM_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Cancer of prostate prostate carcinoma 1,809 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000572/ScoringFiles/PGS000572.txt.gz
PGS000573 PRSWEB_PHECODE185_C61_P_5e-08_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Cancer of prostate prostate carcinoma 31 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000573/ScoringFiles/PGS000573.txt.gz
PGS000574 PRSWEB_PHECODE185_C61_PRS-CS_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Cancer of prostate prostate carcinoma 1,111,493 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000574/ScoringFiles/PGS000574.txt.gz
PGS000575 PRSWEB_PHECODE185_C61_PT_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Cancer of prostate prostate carcinoma 47 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000575/ScoringFiles/PGS000575.txt.gz
PGS000576 PRSWEB_PHECODE185_C61_LASSOSUM_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Cancer of prostate prostate carcinoma 905 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000576/ScoringFiles/PGS000576.txt.gz
PGS000577 PRSWEB_PHECODE185_GWAS-Catalog-r2019-05-03-X185_P_5e-08_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Cancer of prostate prostate carcinoma 117 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000577/ScoringFiles/PGS000577.txt.gz
PGS000578 PRSWEB_PHECODE185_GWAS-Catalog-r2019-05-03-X185_P_5e-08_UKB_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Cancer of prostate prostate carcinoma 117 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000578/ScoringFiles/PGS000578.txt.gz
PGS000579 PRSWEB_PHECODE185_GWAS-Catalog-r2019-05-03-X185_PT_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Cancer of prostate prostate carcinoma 122 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000579/ScoringFiles/PGS000579.txt.gz
PGS000580 PRSWEB_PHECODE185_GWAS-Catalog-r2019-05-03-X185_PT_UKB_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Cancer of prostate prostate carcinoma 118 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000580/ScoringFiles/PGS000580.txt.gz
PGS000581 PRSWEB_PHECODE185_Pca-PRACTICAL_P_5e-08_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Cancer of prostate prostate carcinoma 377 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000581/ScoringFiles/PGS000581.txt.gz
PGS000582 PRSWEB_PHECODE185_Pca-PRACTICAL_P_5e-08_UKB_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Cancer of prostate prostate carcinoma 377 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000582/ScoringFiles/PGS000582.txt.gz
PGS000583 PRSWEB_PHECODE185_Pca-PRACTICAL_PRS-CS_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Cancer of prostate prostate carcinoma 1,119,311 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000583/ScoringFiles/PGS000583.txt.gz
PGS000584 PRSWEB_PHECODE185_Pca-PRACTICAL_PRS-CS_UKB_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Cancer of prostate prostate carcinoma 1,120,596 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000584/ScoringFiles/PGS000584.txt.gz
PGS000585 PRSWEB_PHECODE185_Pca-PRACTICAL_PT_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Cancer of prostate prostate carcinoma 1,301 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000585/ScoringFiles/PGS000585.txt.gz
PGS000586 PRSWEB_PHECODE185_Pca-PRACTICAL_PT_UKB_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Cancer of prostate prostate carcinoma 1,023 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000586/ScoringFiles/PGS000586.txt.gz
PGS000587 PRSWEB_PHECODE185_Pca-PRACTICAL_LASSOSUM_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Cancer of prostate prostate carcinoma 26,418 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000587/ScoringFiles/PGS000587.txt.gz
PGS000588 PRSWEB_PHECODE185_Pca-PRACTICAL_LASSOSUM_UKB_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Cancer of prostate prostate carcinoma 178,259 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000588/ScoringFiles/PGS000588.txt.gz
PGS000589 PRSWEB_PHECODE185_UKBB-SAIGE-HRC-X185_P_5e-08_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Cancer of prostate prostate carcinoma 42 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000589/ScoringFiles/PGS000589.txt.gz
PGS000590 PRSWEB_PHECODE185_UKBB-SAIGE-HRC-X185_PRS-CS_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Cancer of prostate prostate carcinoma 1,119,236 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000590/ScoringFiles/PGS000590.txt.gz
PGS000591 PRSWEB_PHECODE185_UKBB-SAIGE-HRC-X185_PT_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Cancer of prostate prostate carcinoma 80 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000591/ScoringFiles/PGS000591.txt.gz
PGS000592 PRSWEB_PHECODE185_UKBB-SAIGE-HRC-X185_LASSOSUM_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Cancer of prostate prostate carcinoma 1,334 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000592/ScoringFiles/PGS000592.txt.gz
PGS000593 PRSWEB_PHECODE187_C3-MALE-GENITAL_P_5e-08_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Cancer of other male genital organs male reproductive organ cancer 45 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000593/ScoringFiles/PGS000593.txt.gz
PGS000594 PRSWEB_PHECODE187_C3-MALE-GENITAL_PT_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Cancer of other male genital organs male reproductive organ cancer 97 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000594/ScoringFiles/PGS000594.txt.gz
PGS000595 PRSWEB_PHECODE187.2_20001-1045_P_5e-08_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Malignant neoplasm of testis testicular carcinoma 9 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000595/ScoringFiles/PGS000595.txt.gz
PGS000596 PRSWEB_PHECODE187.2_20001-1045_PT_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Malignant neoplasm of testis testicular carcinoma 5 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000596/ScoringFiles/PGS000596.txt.gz
PGS000597 PRSWEB_PHECODE187.2_20001-1045_LASSOSUM_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Malignant neoplasm of testis testicular carcinoma 771 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000597/ScoringFiles/PGS000597.txt.gz
PGS000598 PRSWEB_PHECODE187.2_C3-TESTIS_P_5e-08_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Malignant neoplasm of testis testicular carcinoma 6 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000598/ScoringFiles/PGS000598.txt.gz
PGS000599 PRSWEB_PHECODE187.2_C3-TESTIS_PT_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Malignant neoplasm of testis testicular carcinoma 31 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000599/ScoringFiles/PGS000599.txt.gz
PGS000600 PRSWEB_PHECODE187.2_C3-TESTIS_LASSOSUM_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Malignant neoplasm of testis testicular carcinoma 250 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000600/ScoringFiles/PGS000600.txt.gz
PGS000635 PRSWEB_PHECODE193_UKBB-SAIGE-HRC-X193_PT_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Thyroid cancer thyroid carcinoma 5 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000635/ScoringFiles/PGS000635.txt.gz
PGS000601 PRSWEB_PHECODE187.2_GWAS-Catalog-r2019-05-03-X187.2_P_5e-08_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Malignant neoplasm of testis testicular carcinoma 40 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000601/ScoringFiles/PGS000601.txt.gz
PGS000602 PRSWEB_PHECODE187.2_GWAS-Catalog-r2019-05-03-X187.2_P_5e-08_UKB_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Malignant neoplasm of testis testicular carcinoma 40 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000602/ScoringFiles/PGS000602.txt.gz
PGS000603 PRSWEB_PHECODE187.2_GWAS-Catalog-r2019-05-03-X187.2_PT_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Malignant neoplasm of testis testicular carcinoma 22 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000603/ScoringFiles/PGS000603.txt.gz
PGS000604 PRSWEB_PHECODE187.2_GWAS-Catalog-r2019-05-03-X187.2_PT_UKB_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Malignant neoplasm of testis testicular carcinoma 44 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000604/ScoringFiles/PGS000604.txt.gz
PGS000478 PRSWEB_PHECODE174.1_C3-BREAST-3_PT_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Breast cancer (female) breast carcinoma 120 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000478/ScoringFiles/PGS000478.txt.gz
PGS000605 PRSWEB_PHECODE189.11_GWAS-Catalog-r2019-05-03-X189.11_P_5e-08_UKB_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Malignant neoplasm of kidney, except pelvis kidney cancer 12 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000605/ScoringFiles/PGS000605.txt.gz
PGS000606 PRSWEB_PHECODE189.11_GWAS-Catalog-r2019-05-03-X189.11_PT_UKB_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Malignant neoplasm of kidney, except pelvis kidney cancer 12 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000606/ScoringFiles/PGS000606.txt.gz
PGS000607 PRSWEB_PHECODE189.2_20001-1035_PRS-CS_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Cancer of bladder bladder carcinoma 1,095,241 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000607/ScoringFiles/PGS000607.txt.gz
PGS000608 PRSWEB_PHECODE189.2_C3-BLADDER_PRS-CS_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Cancer of bladder bladder carcinoma 1,097,063 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000608/ScoringFiles/PGS000608.txt.gz
PGS000609 PRSWEB_PHECODE189.2_C67_LASSOSUM_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Cancer of bladder bladder carcinoma 1,130 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000609/ScoringFiles/PGS000609.txt.gz
PGS000610 PRSWEB_PHECODE189.2_GWAS-Catalog-r2019-05-03-X189.2_P_5e-08_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Cancer of bladder bladder carcinoma 13 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000610/ScoringFiles/PGS000610.txt.gz
PGS000611 PRSWEB_PHECODE189.2_GWAS-Catalog-r2019-05-03-X189.2_P_5e-08_UKB_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Cancer of bladder bladder carcinoma 13 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000611/ScoringFiles/PGS000611.txt.gz
PGS000612 PRSWEB_PHECODE189.2_GWAS-Catalog-r2019-05-03-X189.2_PT_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Cancer of bladder bladder carcinoma 13 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000612/ScoringFiles/PGS000612.txt.gz
PGS000613 PRSWEB_PHECODE189.2_GWAS-Catalog-r2019-05-03-X189.2_PT_UKB_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Cancer of bladder bladder carcinoma 15 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000613/ScoringFiles/PGS000613.txt.gz
PGS000614 PRSWEB_PHECODE189.2_UKBB-SAIGE-HRC-X189.2_PRS-CS_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Cancer of bladder bladder carcinoma 1,119,238 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000614/ScoringFiles/PGS000614.txt.gz
PGS000615 PRSWEB_PHECODE189.2_UKBB-SAIGE-HRC-X189.2_PT_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Cancer of bladder bladder carcinoma 106 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000615/ScoringFiles/PGS000615.txt.gz
PGS000616 PRSWEB_PHECODE189.2_UKBB-SAIGE-HRC-X189.2_LASSOSUM_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Cancer of bladder bladder carcinoma 24,359 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000616/ScoringFiles/PGS000616.txt.gz
PGS000617 PRSWEB_PHECODE190_20001-1030_PRS-CS_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Cancer of eye ocular cancer 834,009 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000617/ScoringFiles/PGS000617.txt.gz
PGS000618 PRSWEB_PHECODE191.1_GWAS-Catalog-r2019-05-03-X191.1_P_5e-08_UKB_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Cancer of brain and nervous system central nervous system cancer 23 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000618/ScoringFiles/PGS000618.txt.gz
PGS000619 PRSWEB_PHECODE191.1_GWAS-Catalog-r2019-05-03-X191.1_PT_UKB_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Cancer of brain and nervous system central nervous system cancer 19 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000619/ScoringFiles/PGS000619.txt.gz
PGS000620 PRSWEB_PHECODE191.11_C71_LASSOSUM_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Cancer of brain brain cancer 522 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000620/ScoringFiles/PGS000620.txt.gz
PGS000621 PRSWEB_PHECODE191.11_GWAS-Catalog-r2019-05-03-X191.11_P_5e-08_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Cancer of brain brain cancer 12 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000621/ScoringFiles/PGS000621.txt.gz
PGS000622 PRSWEB_PHECODE191.11_GWAS-Catalog-r2019-05-03-X191.11_P_5e-08_UKB_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Cancer of brain brain cancer 12 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000622/ScoringFiles/PGS000622.txt.gz
PGS000623 PRSWEB_PHECODE191.11_GWAS-Catalog-r2019-05-03-X191.11_PT_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Cancer of brain brain cancer 11 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000623/ScoringFiles/PGS000623.txt.gz
PGS000624 PRSWEB_PHECODE191.11_GWAS-Catalog-r2019-05-03-X191.11_PT_UKB_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Cancer of brain brain cancer 5 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000624/ScoringFiles/PGS000624.txt.gz
PGS000625 PRSWEB_PHECODE191.11_UKBB-SAIGE-HRC-X191.11_PT_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Cancer of brain brain cancer 11 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000625/ScoringFiles/PGS000625.txt.gz
PGS000626 PRSWEB_PHECODE193_20001-1065_PT_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Thyroid cancer thyroid carcinoma 8 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000626/ScoringFiles/PGS000626.txt.gz
PGS000627 PRSWEB_PHECODE193_C3-THYROID-GLAND_PT_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Thyroid cancer thyroid carcinoma 11 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000627/ScoringFiles/PGS000627.txt.gz
PGS000628 PRSWEB_PHECODE193_C3-THYROID-GLAND_LASSOSUM_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Thyroid cancer thyroid carcinoma 656 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000628/ScoringFiles/PGS000628.txt.gz
PGS000629 PRSWEB_PHECODE193_C73_PT_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Thyroid cancer thyroid carcinoma 8 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000629/ScoringFiles/PGS000629.txt.gz
PGS000630 PRSWEB_PHECODE193_GWAS-Catalog-r2019-05-03-X193_P_5e-08_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Thyroid cancer thyroid carcinoma 10 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000630/ScoringFiles/PGS000630.txt.gz
PGS000632 PRSWEB_PHECODE193_GWAS-Catalog-r2019-05-03-X193_PT_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Thyroid cancer thyroid carcinoma 8 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000632/ScoringFiles/PGS000632.txt.gz
PGS000633 PRSWEB_PHECODE193_GWAS-Catalog-r2019-05-03-X193_PT_UKB_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Thyroid cancer thyroid carcinoma 5 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000633/ScoringFiles/PGS000633.txt.gz
PGS000634 PRSWEB_PHECODE193_UKBB-SAIGE-HRC-X193_PRS-CS_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Thyroid cancer thyroid carcinoma 1,119,238 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000634/ScoringFiles/PGS000634.txt.gz
PGS000637 PRSWEB_PHECODE201_20001-1052_PRS-CS_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Hodgkin's disease Hodgkins lymphoma 1,047,511 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000637/ScoringFiles/PGS000637.txt.gz
PGS000638 PRSWEB_PHECODE201_GWAS-Catalog-r2019-05-03-X201_P_5e-08_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Hodgkin's disease Hodgkins lymphoma 16 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000638/ScoringFiles/PGS000638.txt.gz
PGS000639 PRSWEB_PHECODE201_GWAS-Catalog-r2019-05-03-X201_PT_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Hodgkin's disease Hodgkins lymphoma 20 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000639/ScoringFiles/PGS000639.txt.gz
PGS000640 PRSWEB_PHECODE201_UKBB-SAIGE-HRC-X201_LASSOSUM_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Hodgkin's disease Hodgkins lymphoma 1,119,335 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000640/ScoringFiles/PGS000640.txt.gz
PGS000641 PRSWEB_PHECODE202.2_GWAS-Catalog-r2019-05-03-X202.2_P_5e-08_UKB_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Non-Hodgkins lymphoma non-Hodgkins lymphoma 12 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000641/ScoringFiles/PGS000641.txt.gz
PGS000642 PRSWEB_PHECODE202.2_GWAS-Catalog-r2019-05-03-X202.2_PT_UKB_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Non-Hodgkins lymphoma non-Hodgkins lymphoma 10 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000642/ScoringFiles/PGS000642.txt.gz
PGS000643 PRSWEB_PHECODE202.21_C-FOLLICULAR-LYMPHOMA_PRS-CS_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Nodular lymphoma follicular lymphoma 1,048,780 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000643/ScoringFiles/PGS000643.txt.gz
PGS000644 PRSWEB_PHECODE202.21_C-FOLLICULAR-LYMPHOMA_LASSOSUM_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Nodular lymphoma follicular lymphoma 2,209,179 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000644/ScoringFiles/PGS000644.txt.gz
PGS000645 PRSWEB_PHECODE204.1_C-LYMPHOID-LEUKAEMIA_PT_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Lymphoid leukemia lymphoid leukemia 6 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000645/ScoringFiles/PGS000645.txt.gz
PGS000646 PRSWEB_PHECODE204.12_GWAS-Catalog-r2019-05-03-X204.12_P_5e-08_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Lymphoid leukemia, chronic chronic lymphocytic leukemia 32 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000646/ScoringFiles/PGS000646.txt.gz
PGS000647 PRSWEB_PHECODE204.12_GWAS-Catalog-r2019-05-03-X204.12_P_5e-08_UKB_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Lymphoid leukemia, chronic chronic lymphocytic leukemia 32 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000647/ScoringFiles/PGS000647.txt.gz
PGS000648 PRSWEB_PHECODE204.12_GWAS-Catalog-r2019-05-03-X204.12_PT_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Lymphoid leukemia, chronic chronic lymphocytic leukemia 44 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000648/ScoringFiles/PGS000648.txt.gz
PGS000649 PRSWEB_PHECODE204.12_GWAS-Catalog-r2019-05-03-X204.12_PT_UKB_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Lymphoid leukemia, chronic chronic lymphocytic leukemia 27 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000649/ScoringFiles/PGS000649.txt.gz
PGS000650 PRSWEB_PHECODE204.12_UKBB-SAIGE-HRC-X204.12_PT_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Lymphoid leukemia, chronic chronic lymphocytic leukemia 6 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000650/ScoringFiles/PGS000650.txt.gz
PGS000651 PRSWEB_PHECODE204.12_UKBB-SAIGE-HRC-X204.12_LASSOSUM_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Lymphoid leukemia, chronic chronic lymphocytic leukemia 76 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000651/ScoringFiles/PGS000651.txt.gz
PGS000652 PRSWEB_PHECODE204.4_C90_PT_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Multiple myeloma multiple myeloma 27 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000652/ScoringFiles/PGS000652.txt.gz
PGS000654 PRSWEB_PHECODE204.4_GWAS-Catalog-r2019-05-03-X204.4_PT_UKB_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Multiple myeloma multiple myeloma 21 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000654/ScoringFiles/PGS000654.txt.gz
PGS000653 PRSWEB_PHECODE204.4_GWAS-Catalog-r2019-05-03-X204.4_P_5e-08_UKB_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Multiple myeloma multiple myeloma 22 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000653/ScoringFiles/PGS000653.txt.gz
PGS000631 PRSWEB_PHECODE193_GWAS-Catalog-r2019-05-03-X193_P_5e-08_UKB_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Thyroid cancer thyroid carcinoma 10 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000631/ScoringFiles/PGS000631.txt.gz
PGS000486 PRSWEB_PHECODE174.1_GWAS-Catalog-r2019-05-03-X174.1_P_5e-08_UKB_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Breast cancer (female) breast carcinoma 86 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000486/ScoringFiles/PGS000486.txt.gz
PGS000477 PRSWEB_PHECODE174.1_C3-BREAST-3_PRS-CS_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Breast cancer (female) breast carcinoma 1,111,495 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000477/ScoringFiles/PGS000477.txt.gz
PGS000475 PRSWEB_PHECODE174.1_20001-1002_LASSOSUM_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Breast cancer (female) breast carcinoma 30,041 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000475/ScoringFiles/PGS000475.txt.gz
PGS000474 PRSWEB_PHECODE174.1_20001-1002_PT_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Breast cancer (female) breast carcinoma 68 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000474/ScoringFiles/PGS000474.txt.gz
PGS000463 PRSWEB_PHECODE172.22_GWAS-Catalog-r2019-05-03-X172.22_PT_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Squamous cell carcinoma squamous cell carcinoma 7 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000463/ScoringFiles/PGS000463.txt.gz
PGS000447 PRSWEB_PHECODE172.21_20001-1061_PT_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Basal cell carcinoma basal cell carcinoma 72 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000447/ScoringFiles/PGS000447.txt.gz
PGS000356 PRSWEB_PHECODE10001_UKBB-SAIGE-HRC-X10001_LASSOSUM_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Any Cancer cancer 179 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000356/ScoringFiles/PGS000356.txt.gz
PGS000354 PRSWEB_PHECODE10001_UKBB-SAIGE-HRC-X10001_PRS-CS_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Any Cancer cancer 1,118,667 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000354/ScoringFiles/PGS000354.txt.gz
PGS000353 PRSWEB_PHECODE10001_UKBB-SAIGE-HRC-X10001_P_5e-08_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Any Cancer cancer 14 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000353/ScoringFiles/PGS000353.txt.gz

PGS Performance Metrics

Disclaimer: The performance metrics are displayed as reported by the source studies. It is important to note that metrics are not necessarily comparable with each other. For example, metrics depend on the sample characteristics (described by the PGS Catalog Sample Set [PSS] ID), phenotyping, and statistical modelling. Please refer to the source publication for additional guidance on performance.

PGS Performance Metric ID
(PPM ID)
Evaluated Score PGS Sample Set ID
(PSS ID)
Performance Source Trait PGS Effect Sizes
(per SD change)
PGS Classification Metrics Other Metrics Covariates Included in the Model PGS Performance: Other Relevant Information
PPM001257 PGS000572 (PRSWEB_PHECODE185_C3-PROSTATE_LASSOSUM_MGI_20200608) PSS000552 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Cancer of prostate OR: 1.537 [1.433, 1.649]
β: 0.43 (0.0358)
AUROC: 0.616 [0.597, 0.636] Nagelkerke's Pseudo-R²: 0.0418
Brier score: 0.15
Odds Ratio (OR, top 1% vs. Rest): 4.03 [2.59, 6.28]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE185_C3-PROSTATE_LASSOSUM_MGI_20200608
PPM001205 PGS000520 (PRSWEB_PHECODE174.1_iCOGS-ER-negative-BRCA_PRS-CS_UKB_20200608) PSS000570 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Breast cancer [female] OR: 1.188 [1.158, 1.22]
β: 0.172 (0.0133)
AUROC: 0.549 [0.542, 0.556] Nagelkerke's Pseudo-R²: 0.00537
Brier score: 0.0826
Odds Ratio (OR, top 1% vs. Rest): 1.82 [1.48, 2.22]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE174.1_iCOGS-ER-negative-BRCA_PRS-CS_UKB_20200608
PPM001206 PGS000521 (PRSWEB_PHECODE174.1_iCOGS-ER-negative-BRCA_PT_MGI_20200608) PSS000549 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Breast cancer [female] OR: 1.22 [1.149, 1.295]
β: 0.199 (0.0304)
AUROC: 0.548 [0.53, 0.564] Nagelkerke's Pseudo-R²: 0.00934
Brier score: 0.139
Odds Ratio (OR, top 1% vs. Rest): 1.88 [1.18, 2.99]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE174.1_iCOGS-ER-negative-BRCA_PT_MGI_20200608
PPM001208 PGS000523 (PRSWEB_PHECODE174.1_iCOGS-ER-negative-BRCA_LASSOSUM_MGI_20200608) PSS000549 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Breast cancer [female] OR: 1.225 [1.155, 1.299]
β: 0.203 (0.0301)
AUROC: 0.546 [0.529, 0.562] Nagelkerke's Pseudo-R²: 0.00979
Brier score: 0.139
Odds Ratio (OR, top 1% vs. Rest): 2.11 [1.34, 3.33]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE174.1_iCOGS-ER-negative-BRCA_LASSOSUM_MGI_20200608
PPM001209 PGS000524 (PRSWEB_PHECODE174.1_iCOGS-ER-negative-BRCA_LASSOSUM_UKB_20200608) PSS000570 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Breast cancer [female] OR: 1.2 [1.169, 1.231]
β: 0.182 (0.0131)
AUROC: 0.547 [0.54, 0.555] Nagelkerke's Pseudo-R²: 0.0061
Brier score: 0.0825
Odds Ratio (OR, top 1% vs. Rest): 1.72 [1.4, 2.11]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE174.1_iCOGS-ER-negative-BRCA_LASSOSUM_UKB_20200608
PPM001211 PGS000526 (PRSWEB_PHECODE174.1_iCOGS-ER-positive-BRCA_P_5e-08_UKB_20200608) PSS000570 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Breast cancer [female] OR: 1.424 [1.387, 1.461]
β: 0.353 (0.0132)
AUROC: 0.597 [0.59, 0.604] Nagelkerke's Pseudo-R²: 0.0228
Brier score: 0.0819
Odds Ratio (OR, top 1% vs. Rest): 2.68 [2.25, 3.19]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE174.1_iCOGS-ER-positive-BRCA_P_5e-08_UKB_20200608
PPM001212 PGS000527 (PRSWEB_PHECODE174.1_iCOGS-ER-positive-BRCA_PRS-CS_MGI_20200608) PSS000549 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Breast cancer [female] OR: 1.509 [1.418, 1.605]
β: 0.411 (0.0314)
AUROC: 0.613 [0.595, 0.63] Nagelkerke's Pseudo-R²: 0.0383
Brier score: 0.136
Odds Ratio (OR, top 1% vs. Rest): 3.75 [2.55, 5.51]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE174.1_iCOGS-ER-positive-BRCA_PRS-CS_MGI_20200608
PPM001214 PGS000529 (PRSWEB_PHECODE174.1_iCOGS-ER-positive-BRCA_PT_MGI_20200608) PSS000549 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Breast cancer [female] OR: 1.43 [1.346, 1.52]
β: 0.358 (0.0311)
AUROC: 0.597 [0.58, 0.612] Nagelkerke's Pseudo-R²: 0.0281
Brier score: 0.137
Odds Ratio (OR, top 1% vs. Rest): 2.98 [1.98, 4.47]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE174.1_iCOGS-ER-positive-BRCA_PT_MGI_20200608
PPM001042 PGS000357 (PRSWEB_PHECODE145_C3-LIP-ORAL-PHARYNX_PT_MGI_20200608) PSS000535 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Cancer of mouth OR: 1.111 [1.021, 1.208]
β: 0.105 (0.0427)
AUROC: 0.519 [0.498, 0.542] Nagelkerke's Pseudo-R²: 0.0021
Brier score: 0.0829
Odds Ratio (OR, top 1% vs. Rest): 1.26 [0.585, 2.73]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE145_C3-LIP-ORAL-PHARYNX_PT_MGI_20200608
PPM001045 PGS000360 (PRSWEB_PHECODE149.4_C32_LASSOSUM_MGI_20200608) PSS000536 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Cancer of larynx OR: 1.282 [1.09, 1.508]
β: 0.249 (0.0827)
AUROC: 0.57 [0.522, 0.618] Nagelkerke's Pseudo-R²: 0.0112
Brier score: 0.0822
Odds Ratio (OR, top 1% vs. Rest): 2.14 [0.649, 7.06]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE149.4_C32_LASSOSUM_MGI_20200608
PPM001048 PGS000363 (PRSWEB_PHECODE150_C15_PRS-CS_MGI_20200608) PSS000537 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Cancer of esophagus OR: 1.249 [1.075, 1.45]
β: 0.222 (0.0762)
AUROC: 0.564 [0.525, 0.604] Nagelkerke's Pseudo-R²: 0.0089
Brier score: 0.0825
Odds Ratio (OR, top 1% vs. Rest): 2.84 [1.07, 7.54]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE150_C15_PRS-CS_MGI_20200608
PPM001054 PGS000369 (PRSWEB_PHECODE153_CRC-Huyghe_PT_MGI_20200608) PSS000540 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Colorectal cancer OR: 1.214 [1.117, 1.32]
β: 0.194 (0.0426)
AUROC: 0.553 [0.525, 0.577] Nagelkerke's Pseudo-R²: 0.00671
Brier score: 0.0828
Odds Ratio (OR, top 1% vs. Rest): 3.04 [1.79, 5.17]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE153_CRC-Huyghe_PT_MGI_20200608
PPM001057 PGS000372 (PRSWEB_PHECODE153_GWAS-Catalog-r2019-05-03-X153_PT_UKB_20200608) PSS000564 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Colorectal cancer OR: 1.279 [1.225, 1.335]
β: 0.246 (0.0218)
AUROC: 0.565 [0.551, 0.577] Nagelkerke's Pseudo-R²: 0.0111
Brier score: 0.0822
Odds Ratio (OR, top 1% vs. Rest): 2.1 [1.53, 2.89]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE153_GWAS-Catalog-r2019-05-03-X153_PT_UKB_20200608
PPM001061 PGS000376 (PRSWEB_PHECODE153.2_C18_PRS-CS_MGI_20200608) PSS000538 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Colon cancer OR: 1.177 [1.069, 1.297]
β: 0.163 (0.0491)
AUROC: 0.547 [0.518, 0.576] Nagelkerke's Pseudo-R²: 0.0046
Brier score: 0.0832
Odds Ratio (OR, top 1% vs. Rest): 1.65 [0.753, 3.61]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE153.2_C18_PRS-CS_MGI_20200608
PPM001063 PGS000378 (PRSWEB_PHECODE153.2_C3-COLON_PRS-CS_MGI_20200608) PSS000538 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Colon cancer OR: 1.141 [1.038, 1.254]
β: 0.132 (0.0484)
AUROC: 0.536 [0.509, 0.565] Nagelkerke's Pseudo-R²: 0.00301
Brier score: 0.0832
Odds Ratio (OR, top 1% vs. Rest): 1.82 [0.867, 3.84]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE153.2_C3-COLON_PRS-CS_MGI_20200608
PPM001067 PGS000382 (PRSWEB_PHECODE153.2_UKBB-SAIGE-HRC-X153.2_LASSOSUM_MGI_20200608) PSS000538 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Colon cancer OR: 1.247 [1.134, 1.371]
β: 0.221 (0.0483)
AUROC: 0.567 [0.54, 0.594] Nagelkerke's Pseudo-R²: 0.00899
Brier score: 0.083
Odds Ratio (OR, top 1% vs. Rest): 1.17 [0.477, 2.87]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE153.2_UKBB-SAIGE-HRC-X153.2_LASSOSUM_MGI_20200608
PPM001070 PGS000385 (PRSWEB_PHECODE157_GWAS-Catalog-r2019-05-03-X157_P_5e-08_UKB_20200608) PSS000565 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Pancreatic cancer OR: 1.384 [1.235, 1.552]
β: 0.325 (0.0583)
AUROC: 0.589 [0.559, 0.622] Nagelkerke's Pseudo-R²: 0.019
Brier score: 0.082
Odds Ratio (OR, top 1% vs. Rest): 2.58 [1.19, 5.57]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE157_GWAS-Catalog-r2019-05-03-X157_P_5e-08_UKB_20200608
PPM001073 PGS000388 (PRSWEB_PHECODE165.1_C3-BRONCHUS-LUNG_PRS-CS_MGI_20200608) PSS000541 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Cancer of bronchus; lung OR: 1.132 [1.024, 1.25]
β: 0.124 (0.0508)
AUROC: 0.533 [0.505, 0.562] Nagelkerke's Pseudo-R²: 0.00265
Brier score: 0.0827
Odds Ratio (OR, top 1% vs. Rest): 1.96 [0.926, 4.14]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE165.1_C3-BRONCHUS-LUNG_PRS-CS_MGI_20200608
PPM001076 PGS000391 (PRSWEB_PHECODE165.1_GWAS-Catalog-r2019-05-03-X165.1_PT_MGI_20200608) PSS000541 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Cancer of bronchus; lung OR: 1.12 [1.015, 1.237]
β: 0.114 (0.0507)
AUROC: 0.529 [0.503, 0.558] Nagelkerke's Pseudo-R²: 0.00234
Brier score: 0.0827
Odds Ratio (OR, top 1% vs. Rest): 1.75 [0.796, 3.85]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE165.1_GWAS-Catalog-r2019-05-03-X165.1_PT_MGI_20200608
PPM001079 PGS000394 (PRSWEB_PHECODE165.1_LUNG-CANCER-MESOT_PRS-CS_MGI_20200608) PSS000541 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Cancer of bronchus; lung OR: 1.149 [1.04, 1.269]
β: 0.139 (0.0509)
AUROC: 0.539 [0.508, 0.568] Nagelkerke's Pseudo-R²: 0.00329
Brier score: 0.0826
Odds Ratio (OR, top 1% vs. Rest): 2.18 [1.06, 4.46]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE165.1_LUNG-CANCER-MESOT_PRS-CS_MGI_20200608
PPM001082 PGS000397 (PRSWEB_PHECODE165.1_UKBB-SAIGE-HRC-X165.1_LASSOSUM_MGI_20200608) PSS000541 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Cancer of bronchus; lung OR: 1.114 [1.009, 1.23]
β: 0.108 (0.0507)
AUROC: 0.528 [0.503, 0.556] Nagelkerke's Pseudo-R²: 0.00202
Brier score: 0.0827
Odds Ratio (OR, top 1% vs. Rest): 1.03 [0.387, 2.77]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE165.1_UKBB-SAIGE-HRC-X165.1_LASSOSUM_MGI_20200608
PPM001085 PGS000400 (PRSWEB_PHECODE172_C3-SKIN_P_5e-08_MGI_20200608) PSS000548 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Skin cancer OR: 1.342 [1.291, 1.395]
β: 0.294 (0.0197)
AUROC: 0.581 [0.57, 0.592] Nagelkerke's Pseudo-R²: 0.0201
Brier score: 0.146
Odds Ratio (OR, top 1% vs. Rest): 2.2 [1.63, 2.98]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE172_C3-SKIN_P_5e-08_MGI_20200608
PPM001088 PGS000403 (PRSWEB_PHECODE172_C3-SKIN_LASSOSUM_MGI_20200608) PSS000548 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Skin cancer OR: 1.359 [1.307, 1.413]
β: 0.307 (0.0199)
AUROC: 0.584 [0.573, 0.594] Nagelkerke's Pseudo-R²: 0.0219
Brier score: 0.146
Odds Ratio (OR, top 1% vs. Rest): 1.65 [1.2, 2.27]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE172_C3-SKIN_LASSOSUM_MGI_20200608
PPM001091 PGS000406 (PRSWEB_PHECODE172_UKBB-SAIGE-HRC-X172_PT_MGI_20200608) PSS000548 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Skin cancer OR: 1.392 [1.339, 1.447]
β: 0.331 (0.0199)
AUROC: 0.591 [0.581, 0.602] Nagelkerke's Pseudo-R²: 0.0249
Brier score: 0.146
Odds Ratio (OR, top 1% vs. Rest): 2.51 [1.89, 3.34]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE172_UKBB-SAIGE-HRC-X172_PT_MGI_20200608
PPM001095 PGS000410 (PRSWEB_PHECODE172.1_20001-1059_PT_MGI_20200608) PSS000543 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Melanomas of skin, dx or hx OR: 1.399 [1.327, 1.476]
β: 0.336 (0.0272)
AUROC: 0.578 [0.562, 0.594] Nagelkerke's Pseudo-R²: 0.0239
Brier score: 0.0956
Odds Ratio (OR, top 1% vs. Rest): 2.65 [1.79, 3.93]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE172.1_20001-1059_PT_MGI_20200608
PPM001098 PGS000413 (PRSWEB_PHECODE172.1_C3-MELANOMA-SKIN_PRS-CS_MGI_20200608) PSS000543 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Melanomas of skin, dx or hx OR: 1.27 [1.199, 1.346]
β: 0.239 (0.0294)
AUROC: 0.568 [0.552, 0.584] Nagelkerke's Pseudo-R²: 0.0109
Brier score: 0.0964
Odds Ratio (OR, top 1% vs. Rest): 2.09 [1.35, 3.22]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE172.1_C3-MELANOMA-SKIN_PRS-CS_MGI_20200608
PPM001101 PGS000416 (PRSWEB_PHECODE172.1_C43_P_5e-08_MGI_20200608) PSS000543 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Melanomas of skin, dx or hx OR: 1.473 [1.394, 1.557]
β: 0.388 (0.0282)
AUROC: 0.598 [0.582, 0.613] Nagelkerke's Pseudo-R²: 0.0297
Brier score: 0.0952
Odds Ratio (OR, top 1% vs. Rest): 2.88 [1.96, 4.21]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE172.1_C43_P_5e-08_MGI_20200608
PPM001103 PGS000418 (PRSWEB_PHECODE172.1_C43_PT_MGI_20200608) PSS000543 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Melanomas of skin, dx or hx OR: 1.473 [1.394, 1.557]
β: 0.388 (0.0282)
AUROC: 0.598 [0.582, 0.613] Nagelkerke's Pseudo-R²: 0.0297
Brier score: 0.0952
Odds Ratio (OR, top 1% vs. Rest): 2.88 [1.96, 4.21]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE172.1_C43_PT_MGI_20200608
PPM001106 PGS000421 (PRSWEB_PHECODE172.1_GWAS-Catalog-r2019-05-03-X172.1_P_5e-08_MGI_20200608) PSS000543 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Melanomas of skin, dx or hx OR: 1.453 [1.37, 1.541]
β: 0.374 (0.03)
AUROC: 0.6 [0.584, 0.616] Nagelkerke's Pseudo-R²: 0.0257
Brier score: 0.0955
Odds Ratio (OR, top 1% vs. Rest): 2.39 [1.58, 3.61]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE172.1_GWAS-Catalog-r2019-05-03-X172.1_P_5e-08_MGI_20200608
PPM001110 PGS000425 (PRSWEB_PHECODE172.1_Melanoma-Ransohoff_P_5e-08_MGI_20200608) PSS000543 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Melanomas of skin, dx or hx OR: 1.453 [1.369, 1.542]
β: 0.374 (0.0304)
AUROC: 0.601 [0.585, 0.617] Nagelkerke's Pseudo-R²: 0.0255
Brier score: 0.0955
Odds Ratio (OR, top 1% vs. Rest): 2.54 [1.7, 3.8]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE172.1_Melanoma-Ransohoff_P_5e-08_MGI_20200608
PPM001118 PGS000433 (PRSWEB_PHECODE172.2_C3-OTHER-SKIN_P_5e-08_MGI_20200608) PSS000546 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Other non-epithelial cancer of skin OR: 1.367 [1.31, 1.426]
β: 0.312 (0.0215)
AUROC: 0.584 [0.572, 0.598] Nagelkerke's Pseudo-R²: 0.0215
Brier score: 0.137
Odds Ratio (OR, top 1% vs. Rest): 2.73 [2.01, 3.72]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE172.2_C3-OTHER-SKIN_P_5e-08_MGI_20200608
PPM001121 PGS000436 (PRSWEB_PHECODE172.2_C3-OTHER-SKIN_LASSOSUM_MGI_20200608) PSS000546 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Other non-epithelial cancer of skin OR: 1.361 [1.305, 1.42]
β: 0.308 (0.0216)
AUROC: 0.584 [0.571, 0.596] Nagelkerke's Pseudo-R²: 0.021
Brier score: 0.137
Odds Ratio (OR, top 1% vs. Rest): 2.22 [1.61, 3.06]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE172.2_C3-OTHER-SKIN_LASSOSUM_MGI_20200608
PPM001124 PGS000439 (PRSWEB_PHECODE172.2_C44_PT_MGI_20200608) PSS000546 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Other non-epithelial cancer of skin OR: 1.348 [1.293, 1.407]
β: 0.299 (0.0216)
AUROC: 0.583 [0.57, 0.595] Nagelkerke's Pseudo-R²: 0.0197
Brier score: 0.137
Odds Ratio (OR, top 1% vs. Rest): 2.17 [1.57, 3.01]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE172.2_C44_PT_MGI_20200608
PPM001127 PGS000442 (PRSWEB_PHECODE172.2_UKBB-SAIGE-HRC-X172.2_PRS-CS_MGI_20200608) PSS000546 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Other non-epithelial cancer of skin OR: 1.357 [1.301, 1.417]
β: 0.306 (0.0217)
AUROC: 0.584 [0.572, 0.595] Nagelkerke's Pseudo-R²: 0.0201
Brier score: 0.137
Odds Ratio (OR, top 1% vs. Rest): 2.35 [1.71, 3.22]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE172.2_UKBB-SAIGE-HRC-X172.2_PRS-CS_MGI_20200608
PPM001130 PGS000445 (PRSWEB_PHECODE172.21_20001-1061_P_5e-08_MGI_20200608) PSS000544 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Basal cell carcinoma OR: 1.334 [1.264, 1.409]
β: 0.289 (0.0278)
AUROC: 0.571 [0.555, 0.587] Nagelkerke's Pseudo-R²: 0.0184
Brier score: 0.108
Odds Ratio (OR, top 1% vs. Rest): 2.54 [1.72, 3.74]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE172.21_20001-1061_P_5e-08_MGI_20200608
PPM001132 PGS000447 (PRSWEB_PHECODE172.21_20001-1061_PT_MGI_20200608) PSS000544 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Basal cell carcinoma OR: 1.398 [1.322, 1.477]
β: 0.335 (0.0282)
AUROC: 0.591 [0.575, 0.607] Nagelkerke's Pseudo-R²: 0.0237
Brier score: 0.108
Odds Ratio (OR, top 1% vs. Rest): 2.5 [1.68, 3.71]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE172.21_20001-1061_PT_MGI_20200608
PPM001135 PGS000450 (PRSWEB_PHECODE172.21_20001-1073_PT_MGI_20200608) PSS000544 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Basal cell carcinoma OR: 1.079 [1.022, 1.139]
β: 0.0759 (0.0278)
AUROC: 0.504 [0.489, 0.52] Nagelkerke's Pseudo-R²: 0.00145
Brier score: 0.109
Odds Ratio (OR, top 1% vs. Rest): 1.42 [0.882, 2.3]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE172.21_20001-1073_PT_MGI_20200608
PPM001138 PGS000453 (PRSWEB_PHECODE172.21_BCC-Chahal_P_5e-08_UKB_20200608) PSS000568 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Basal cell carcinoma OR: 1.511 [1.47, 1.554]
β: 0.413 (0.0142)
AUROC: 0.611 [0.604, 0.619] Nagelkerke's Pseudo-R²: 0.0301
Brier score: 0.0813
Odds Ratio (OR, top 1% vs. Rest): 2.8 [2.33, 3.36]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE172.21_BCC-Chahal_P_5e-08_UKB_20200608
PPM001142 PGS000457 (PRSWEB_PHECODE172.21_GWAS-Catalog-r2019-05-03-X172.21_P_5e-08_UKB_20200608) PSS000568 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Basal cell carcinoma OR: 1.535 [1.493, 1.579]
β: 0.429 (0.0144)
AUROC: 0.617 [0.609, 0.625] Nagelkerke's Pseudo-R²: 0.0322
Brier score: 0.0813
Odds Ratio (OR, top 1% vs. Rest): 3.11 [2.6, 3.71]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE172.21_GWAS-Catalog-r2019-05-03-X172.21_P_5e-08_UKB_20200608
PPM001145 PGS000460 (PRSWEB_PHECODE172.22_20001-1062_LASSOSUM_MGI_20200608) PSS000545 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Squamous cell carcinoma OR: 1.096 [1.025, 1.172]
β: 0.0917 (0.0344)
AUROC: 0.523 [0.503, 0.543] Nagelkerke's Pseudo-R²: 0.00155
Brier score: 0.0996
Odds Ratio (OR, top 1% vs. Rest): 1.56 [0.892, 2.74]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE172.22_20001-1062_LASSOSUM_MGI_20200608
PPM001148 PGS000463 (PRSWEB_PHECODE172.22_GWAS-Catalog-r2019-05-03-X172.22_PT_MGI_20200608) PSS000545 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Squamous cell carcinoma OR: 1.448 [1.356, 1.546]
β: 0.37 (0.0335)
AUROC: 0.593 [0.573, 0.613] Nagelkerke's Pseudo-R²: 0.0268
Brier score: 0.0977
Odds Ratio (OR, top 1% vs. Rest): 3.74 [2.46, 5.68]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE172.22_GWAS-Catalog-r2019-05-03-X172.22_PT_MGI_20200608
PPM001151 PGS000466 (PRSWEB_PHECODE172.22_cSCC-Chahal_P_5e-08_UKB_20200608) PSS000569 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Squamous cell carcinoma β: 0.283 (0.0138)
OR: 1.327 [1.292, 1.364]
AUROC: 0.57 [0.562, 0.578] Nagelkerke's Pseudo-R²: 0.0146
Brier score: 0.082
Odds Ratio (OR, top 1% vs. Rest): 1.75 [1.4, 2.18]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE172.22_cSCC-Chahal_P_5e-08_UKB_20200608
PPM001154 PGS000469 (PRSWEB_PHECODE172.3_UKBB-SAIGE-HRC-X172.3_PRS-CS_MGI_20200608) PSS000547 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Carcinoma in situ of skin OR: 1.09 [1.001, 1.188]
β: 0.0865 (0.0437)
AUROC: 0.524 [0.499, 0.549] Nagelkerke's Pseudo-R²: 0.00141
Brier score: 0.0939
Odds Ratio (OR, top 1% vs. Rest): 1.48 [0.703, 3.1]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE172.3_UKBB-SAIGE-HRC-X172.3_PRS-CS_MGI_20200608
PPM001157 PGS000472 (PRSWEB_PHECODE174.1_20001-1002_P_5e-08_MGI_20200608) PSS000549 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Breast cancer [female] OR: 1.343 [1.266, 1.426]
β: 0.295 (0.0303)
AUROC: 0.579 [0.561, 0.597] Nagelkerke's Pseudo-R²: 0.0204
Brier score: 0.138
Odds Ratio (OR, top 1% vs. Rest): 2.32 [1.49, 3.61]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE174.1_20001-1002_P_5e-08_MGI_20200608
PPM001160 PGS000475 (PRSWEB_PHECODE174.1_20001-1002_LASSOSUM_MGI_20200608) PSS000549 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Breast cancer [female] OR: 1.349 [1.269, 1.434]
β: 0.299 (0.0312)
AUROC: 0.586 [0.57, 0.603] Nagelkerke's Pseudo-R²: 0.0196
Brier score: 0.138
Odds Ratio (OR, top 1% vs. Rest): 1.59 [0.962, 2.62]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE174.1_20001-1002_LASSOSUM_MGI_20200608
PPM001163 PGS000478 (PRSWEB_PHECODE174.1_C3-BREAST-3_PT_MGI_20200608) PSS000549 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Breast cancer [female] OR: 1.411 [1.328, 1.5]
β: 0.344 (0.031)
AUROC: 0.595 [0.578, 0.611] Nagelkerke's Pseudo-R²: 0.0257
Brier score: 0.137
Odds Ratio (OR, top 1% vs. Rest): 2.31 [1.47, 3.61]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE174.1_C3-BREAST-3_PT_MGI_20200608
PPM001166 PGS000481 (PRSWEB_PHECODE174.1_C50_PRS-CS_MGI_20200608) PSS000549 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Breast cancer [female] OR: 1.323 [1.246, 1.406]
β: 0.28 (0.0307)
AUROC: 0.578 [0.56, 0.596] Nagelkerke's Pseudo-R²: 0.0183
Brier score: 0.138
Odds Ratio (OR, top 1% vs. Rest): 2.03 [1.29, 3.2]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE174.1_C50_PRS-CS_MGI_20200608
PPM001169 PGS000484 (PRSWEB_PHECODE174.1_D05_PT_MGI_20200608) PSS000549 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Breast cancer [female] OR: 1.12 [1.056, 1.187]
β: 0.113 (0.0297)
AUROC: 0.52 [0.504, 0.538] Nagelkerke's Pseudo-R²: 0.00286
Brier score: 0.139
Odds Ratio (OR, top 1% vs. Rest): 1.39 [0.817, 2.36]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE174.1_D05_PT_MGI_20200608
PPM001172 PGS000487 (PRSWEB_PHECODE174.1_GWAS-Catalog-r2019-05-03-X174.1_PT_MGI_20200608) PSS000549 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Breast cancer [female] OR: 1.488 [1.399, 1.582]
β: 0.397 (0.0313)
AUROC: 0.607 [0.589, 0.623] Nagelkerke's Pseudo-R²: 0.0346
Brier score: 0.136
Odds Ratio (OR, top 1% vs. Rest): 3.06 [2.04, 4.6]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE174.1_GWAS-Catalog-r2019-05-03-X174.1_PT_MGI_20200608
PPM001175 PGS000490 (PRSWEB_PHECODE174.1_Onco-iCOGS-ER-negative-BRCA_P_5e-08_UKB_20200608) PSS000570 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Breast cancer [female] β: 0.221 (0.0132)
OR: 1.248 [1.216, 1.28]
AUROC: 0.559 [0.551, 0.566] Nagelkerke's Pseudo-R²: 0.00891
Brier score: 0.0824
Odds Ratio (OR, top 1% vs. Rest): 2.03 [1.67, 2.46]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE174.1_Onco-iCOGS-ER-negative-BRCA_P_5e-08_UKB_20200608
PPM001178 PGS000493 (PRSWEB_PHECODE174.1_Onco-iCOGS-ER-negative-BRCA_PT_MGI_20200608) PSS000549 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Breast cancer [female] OR: 1.31 [1.234, 1.391]
β: 0.27 (0.0306)
AUROC: 0.576 [0.559, 0.593] Nagelkerke's Pseudo-R²: 0.0173
Brier score: 0.138
Odds Ratio (OR, top 1% vs. Rest): 1.84 [1.14, 2.97]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE174.1_Onco-iCOGS-ER-negative-BRCA_PT_MGI_20200608
PPM001181 PGS000496 (PRSWEB_PHECODE174.1_Onco-iCOGS-ER-negative-BRCA_LASSOSUM_UKB_20200608) PSS000570 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Breast cancer [female] OR: 1.323 [1.289, 1.358]
β: 0.28 (0.0133)
AUROC: 0.576 [0.568, 0.583] Nagelkerke's Pseudo-R²: 0.0141
Brier score: 0.0822
Odds Ratio (OR, top 1% vs. Rest): 2.25 [1.86, 2.71]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE174.1_Onco-iCOGS-ER-negative-BRCA_LASSOSUM_UKB_20200608
PPM001195 PGS000510 (PRSWEB_PHECODE174.1_Onco-iCOGS-Overall-BRCA_PT_UKB_20200608) PSS000570 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Breast cancer [female] OR: 1.612 [1.57, 1.656]
β: 0.478 (0.0136)
AUROC: 0.63 [0.623, 0.637] Nagelkerke's Pseudo-R²: 0.0401
Brier score: 0.0811
Odds Ratio (OR, top 1% vs. Rest): 3.32 [2.83, 3.9]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE174.1_Onco-iCOGS-Overall-BRCA_PT_UKB_20200608
PPM001198 PGS000513 (PRSWEB_PHECODE174.1_UKBB-SAIGE-HRC-X174.1_P_5e-08_MGI_20200608) PSS000549 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Breast cancer [female] OR: 1.402 [1.32, 1.489]
β: 0.338 (0.0307)
AUROC: 0.595 [0.577, 0.612] Nagelkerke's Pseudo-R²: 0.0259
Brier score: 0.137
Odds Ratio (OR, top 1% vs. Rest): 1.8 [1.12, 2.91]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE174.1_UKBB-SAIGE-HRC-X174.1_P_5e-08_MGI_20200608
PPM001201 PGS000516 (PRSWEB_PHECODE174.1_UKBB-SAIGE-HRC-X174.1_LASSOSUM_MGI_20200608) PSS000549 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Breast cancer [female] OR: 1.477 [1.39, 1.57]
β: 0.39 (0.031)
AUROC: 0.609 [0.592, 0.624] Nagelkerke's Pseudo-R²: 0.034
Brier score: 0.137
Odds Ratio (OR, top 1% vs. Rest): 1.94 [1.21, 3.11]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE174.1_UKBB-SAIGE-HRC-X174.1_LASSOSUM_MGI_20200608
PPM001273 PGS000588 (PRSWEB_PHECODE185_Pca-PRACTICAL_LASSOSUM_UKB_20200608) PSS000573 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Cancer of prostate OR: 2.127 [2.043, 2.215]
β: 0.755 (0.0206)
AUROC: 0.699 [0.69, 0.71] Nagelkerke's Pseudo-R²: 0.0943
Brier score: 0.0794
Odds Ratio (OR, top 1% vs. Rest): 5.88 [4.85, 7.14]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE185_Pca-PRACTICAL_LASSOSUM_UKB_20200608
PPM001204 PGS000519 (PRSWEB_PHECODE174.1_iCOGS-ER-negative-BRCA_PRS-CS_MGI_20200608) PSS000549 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Breast cancer [female] OR: 1.151 [1.084, 1.221]
β: 0.14 (0.0305)
AUROC: 0.539 [0.52, 0.556] Nagelkerke's Pseudo-R²: 0.00453
Brier score: 0.139
Odds Ratio (OR, top 1% vs. Rest): 1.51 [0.907, 2.51]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE174.1_iCOGS-ER-negative-BRCA_PRS-CS_MGI_20200608
PPM001207 PGS000522 (PRSWEB_PHECODE174.1_iCOGS-ER-negative-BRCA_PT_UKB_20200608) PSS000570 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Breast cancer [female] OR: 1.201 [1.171, 1.233]
β: 0.183 (0.0131)
AUROC: 0.547 [0.54, 0.555] Nagelkerke's Pseudo-R²: 0.00619
Brier score: 0.0825
Odds Ratio (OR, top 1% vs. Rest): 1.73 [1.41, 2.13]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE174.1_iCOGS-ER-negative-BRCA_PT_UKB_20200608
PPM001210 PGS000525 (PRSWEB_PHECODE174.1_iCOGS-ER-positive-BRCA_P_5e-08_MGI_20200608) PSS000549 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Breast cancer [female] OR: 1.427 [1.343, 1.516]
β: 0.356 (0.0309)
AUROC: 0.597 [0.58, 0.614] Nagelkerke's Pseudo-R²: 0.0285
Brier score: 0.137
Odds Ratio (OR, top 1% vs. Rest): 2.28 [1.46, 3.56]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE174.1_iCOGS-ER-positive-BRCA_P_5e-08_MGI_20200608
PPM001188 PGS000503 (PRSWEB_PHECODE174.1_Onco-iCOGS-ER-positive-BRCA_LASSOSUM_MGI_20200608) PSS000549 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Breast cancer [female] OR: 1.656 [1.554, 1.766]
β: 0.505 (0.0326)
AUROC: 0.634 [0.618, 0.65] Nagelkerke's Pseudo-R²: 0.0546
Brier score: 0.135
Odds Ratio (OR, top 1% vs. Rest): 4.03 [2.78, 5.85]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE174.1_Onco-iCOGS-ER-positive-BRCA_LASSOSUM_MGI_20200608
PPM001192 PGS000507 (PRSWEB_PHECODE174.1_Onco-iCOGS-Overall-BRCA_PRS-CS_MGI_20200608) PSS000549 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Breast cancer [female] OR: 1.772 [1.659, 1.891]
β: 0.572 (0.0334)
AUROC: 0.651 [0.635, 0.666] Nagelkerke's Pseudo-R²: 0.0661
Brier score: 0.133
Odds Ratio (OR, top 1% vs. Rest): 3.22 [2.15, 4.81]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE174.1_Onco-iCOGS-Overall-BRCA_PRS-CS_MGI_20200608
PPM001213 PGS000528 (PRSWEB_PHECODE174.1_iCOGS-ER-positive-BRCA_PRS-CS_UKB_20200608) PSS000570 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Breast cancer [female] OR: 1.513 [1.474, 1.554]
β: 0.414 (0.0136)
AUROC: 0.614 [0.607, 0.62] Nagelkerke's Pseudo-R²: 0.0303
Brier score: 0.0816
Odds Ratio (OR, top 1% vs. Rest): 2.98 [2.52, 3.52]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE174.1_iCOGS-ER-positive-BRCA_PRS-CS_UKB_20200608
PPM001216 PGS000531 (PRSWEB_PHECODE174.1_iCOGS-ER-positive-BRCA_LASSOSUM_MGI_20200608) PSS000549 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Breast cancer [female] OR: 1.501 [1.411, 1.596]
β: 0.406 (0.0314)
AUROC: 0.61 [0.594, 0.626] Nagelkerke's Pseudo-R²: 0.037
Brier score: 0.136
Odds Ratio (OR, top 1% vs. Rest): 2.29 [1.47, 3.59]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE174.1_iCOGS-ER-positive-BRCA_LASSOSUM_MGI_20200608
PPM001219 PGS000534 (PRSWEB_PHECODE174.1_iCOGS-Overall-BRCA_P_5e-08_UKB_20200608) PSS000570 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Breast cancer [female] OR: 1.443 [1.406, 1.481]
β: 0.367 (0.0132)
AUROC: 0.601 [0.594, 0.608] Nagelkerke's Pseudo-R²: 0.0246
Brier score: 0.0818
Odds Ratio (OR, top 1% vs. Rest): 2.5 [2.09, 2.99]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE174.1_iCOGS-Overall-BRCA_P_5e-08_UKB_20200608
PPM001222 PGS000537 (PRSWEB_PHECODE174.1_iCOGS-Overall-BRCA_PT_MGI_20200608) PSS000549 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Breast cancer [female] OR: 1.498 [1.408, 1.593]
β: 0.404 (0.0314)
AUROC: 0.609 [0.592, 0.626] Nagelkerke's Pseudo-R²: 0.0353
Brier score: 0.136
Odds Ratio (OR, top 1% vs. Rest): 3.44 [2.31, 5.13]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE174.1_iCOGS-Overall-BRCA_PT_MGI_20200608
PPM001225 PGS000540 (PRSWEB_PHECODE174.1_iCOGS-Overall-BRCA_LASSOSUM_UKB_20200608) PSS000570 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Breast cancer [female] OR: 1.528 [1.489, 1.569]
β: 0.424 (0.0134)
AUROC: 0.615 [0.607, 0.622] Nagelkerke's Pseudo-R²: 0.0322
Brier score: 0.0814
Odds Ratio (OR, top 1% vs. Rest): 3.55 [3.04, 4.16]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE174.1_iCOGS-Overall-BRCA_LASSOSUM_UKB_20200608
PPM001228 PGS000543 (PRSWEB_PHECODE184_C3-FEMALE-GENITAL_PT_MGI_20200608) PSS000551 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Cancer of other female genital organs OR: 1.144 [1.043, 1.255]
β: 0.135 (0.0472)
AUROC: 0.51 [0.483, 0.537] Nagelkerke's Pseudo-R²: 0.00332
Brier score: 0.0836
Odds Ratio (OR, top 1% vs. Rest): 1.63 [0.743, 3.57]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE184_C3-FEMALE-GENITAL_PT_MGI_20200608
PPM001231 PGS000546 (PRSWEB_PHECODE184.11_Phelan-ENOC_PRS-CS_UKB_20200608) PSS000572 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Malignant neoplasm of ovary OR: 1.119 [1.017, 1.231]
β: 0.112 (0.0488)
AUROC: 0.526 [0.498, 0.554] Nagelkerke's Pseudo-R²: 0.00221
Brier score: 0.0827
Odds Ratio (OR, top 1% vs. Rest): 1.97 [0.973, 4.0]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE184.11_Phelan-ENOC_PRS-CS_UKB_20200608
PPM001234 PGS000549 (PRSWEB_PHECODE184.11_Phelan-IEOC_P_5e-08_UKB_20200608) PSS000572 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Malignant neoplasm of ovary OR: 1.263 [1.15, 1.387]
β: 0.234 (0.0479)
AUROC: 0.567 [0.539, 0.595] Nagelkerke's Pseudo-R²: 0.00996
Brier score: 0.0824
Odds Ratio (OR, top 1% vs. Rest): 1.76 [0.839, 3.69]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE184.11_Phelan-IEOC_P_5e-08_UKB_20200608
PPM001237 PGS000552 (PRSWEB_PHECODE184.11_Phelan-IEOC_LASSOSUM_UKB_20200608) PSS000572 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Malignant neoplasm of ovary OR: 1.19 [1.084, 1.308]
β: 0.174 (0.048)
AUROC: 0.552 [0.523, 0.58] Nagelkerke's Pseudo-R²: 0.00552
Brier score: 0.0825
Odds Ratio (OR, top 1% vs. Rest): 1.97 [0.97, 3.99]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE184.11_Phelan-IEOC_LASSOSUM_UKB_20200608
PPM001240 PGS000555 (PRSWEB_PHECODE184.11_Phelan-LSASBOC_PT_UKB_20200608) PSS000572 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Malignant neoplasm of ovary OR: 1.133 [1.03, 1.245]
β: 0.125 (0.0483)
AUROC: 0.539 [0.513, 0.568] Nagelkerke's Pseudo-R²: 0.00282
Brier score: 0.0826
Odds Ratio (OR, top 1% vs. Rest): 2.18 [1.11, 4.3]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE184.11_Phelan-LSASBOC_PT_UKB_20200608
PPM001243 PGS000558 (PRSWEB_PHECODE184.11_Phelan-OCCC_LASSOSUM_UKB_20200608) PSS000572 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Malignant neoplasm of ovary OR: 1.207 [1.102, 1.321]
β: 0.188 (0.0463)
AUROC: 0.546 [0.52, 0.574] Nagelkerke's Pseudo-R²: 0.00676
Brier score: 0.0824
Odds Ratio (OR, top 1% vs. Rest): 1.76 [0.839, 3.69]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE184.11_Phelan-OCCC_LASSOSUM_UKB_20200608
PPM001246 PGS000561 (PRSWEB_PHECODE184.11_Phelan-SIOC_PRS-CS_MGI_20200608) PSS000550 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Malignant neoplasm of ovary OR: 1.185 [1.011, 1.39]
β: 0.17 (0.0812)
AUROC: 0.552 [0.513, 0.598] Nagelkerke's Pseudo-R²: 0.00517
Brier score: 0.0827
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE184.11_Phelan-SIOC_PRS-CS_MGI_20200608
PPM001249 PGS000564 (PRSWEB_PHECODE184.11_Phelan-SIOC_LASSOSUM_UKB_20200608) PSS000572 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Malignant neoplasm of ovary OR: 1.215 [1.106, 1.336]
β: 0.195 (0.0481)
AUROC: 0.556 [0.529, 0.583] Nagelkerke's Pseudo-R²: 0.00692
Brier score: 0.0825
Odds Ratio (OR, top 1% vs. Rest): 1.76 [0.839, 3.69]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE184.11_Phelan-SIOC_LASSOSUM_UKB_20200608
PPM001258 PGS000573 (PRSWEB_PHECODE185_C61_P_5e-08_MGI_20200608) PSS000552 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Cancer of prostate OR: 1.603 [1.495, 1.718]
β: 0.472 (0.0355)
AUROC: 0.622 [0.603, 0.641] Nagelkerke's Pseudo-R²: 0.0497
Brier score: 0.149
Odds Ratio (OR, top 1% vs. Rest): 2.93 [1.83, 4.7]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE185_C61_P_5e-08_MGI_20200608
PPM001260 PGS000575 (PRSWEB_PHECODE185_C61_PT_MGI_20200608) PSS000552 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Cancer of prostate OR: 1.577 [1.47, 1.692]
β: 0.456 (0.0359)
AUROC: 0.619 [0.601, 0.637] Nagelkerke's Pseudo-R²: 0.0456
Brier score: 0.149
Odds Ratio (OR, top 1% vs. Rest): 3.1 [1.96, 4.92]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE185_C61_PT_MGI_20200608
PPM001264 PGS000579 (PRSWEB_PHECODE185_GWAS-Catalog-r2019-05-03-X185_PT_MGI_20200608) PSS000552 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Cancer of prostate OR: 1.747 [1.626, 1.876]
β: 0.558 (0.0364)
AUROC: 0.646 [0.627, 0.664] Nagelkerke's Pseudo-R²: 0.0675
Brier score: 0.147
Odds Ratio (OR, top 1% vs. Rest): 3.53 [2.26, 5.51]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE185_GWAS-Catalog-r2019-05-03-X185_PT_MGI_20200608
PPM001267 PGS000582 (PRSWEB_PHECODE185_Pca-PRACTICAL_P_5e-08_UKB_20200608) PSS000573 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Cancer of prostate OR: 1.957 [1.882, 2.035]
β: 0.671 (0.0201)
AUROC: 0.681 [0.671, 0.692] Nagelkerke's Pseudo-R²: 0.0776
Brier score: 0.0803
Odds Ratio (OR, top 1% vs. Rest): 4.85 [3.95, 5.95]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE185_Pca-PRACTICAL_P_5e-08_UKB_20200608
PPM001270 PGS000585 (PRSWEB_PHECODE185_Pca-PRACTICAL_PT_MGI_20200608) PSS000552 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Cancer of prostate OR: 1.907 [1.771, 2.053]
β: 0.645 (0.0378)
AUROC: 0.67 [0.652, 0.688] Nagelkerke's Pseudo-R²: 0.0837
Brier score: 0.145
Odds Ratio (OR, top 1% vs. Rest): 3.3 [2.06, 5.29]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE185_Pca-PRACTICAL_PT_MGI_20200608
PPM001276 PGS000591 (PRSWEB_PHECODE185_UKBB-SAIGE-HRC-X185_PT_MGI_20200608) PSS000552 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Cancer of prostate OR: 1.608 [1.498, 1.725]
β: 0.475 (0.0359)
AUROC: 0.627 [0.608, 0.645] Nagelkerke's Pseudo-R²: 0.051
Brier score: 0.149
Odds Ratio (OR, top 1% vs. Rest): 3.18 [2.01, 5.02]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE185_UKBB-SAIGE-HRC-X185_PT_MGI_20200608
PPM001279 PGS000594 (PRSWEB_PHECODE187_C3-MALE-GENITAL_PT_MGI_20200608) PSS000554 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Cancer of other male genital organs OR: 1.227 [1.029, 1.464]
β: 0.205 (0.0899)
AUROC: 0.558 [0.506, 0.606] Nagelkerke's Pseudo-R²: 0.00729
Brier score: 0.083
Odds Ratio (OR, top 1% vs. Rest): 1.04 [0.183, 5.95]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE187_C3-MALE-GENITAL_PT_MGI_20200608
PPM001282 PGS000597 (PRSWEB_PHECODE187.2_20001-1045_LASSOSUM_MGI_20200608) PSS000553 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Malignant neoplasm of testis OR: 1.667 [1.296, 2.143]
β: 0.511 (0.128)
AUROC: 0.656 [0.593, 0.717] Nagelkerke's Pseudo-R²: 0.0487
Brier score: 0.084
Odds Ratio (OR, top 1% vs. Rest): 2.72 [0.568, 13.1]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE187.2_20001-1045_LASSOSUM_MGI_20200608
PPM001285 PGS000600 (PRSWEB_PHECODE187.2_C3-TESTIS_LASSOSUM_MGI_20200608) PSS000553 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Malignant neoplasm of testis OR: 1.619 [1.267, 2.067]
β: 0.482 (0.125)
AUROC: 0.636 [0.565, 0.698] Nagelkerke's Pseudo-R²: 0.046
Brier score: 0.0839
Odds Ratio (OR, top 1% vs. Rest): 6.35 [1.81, 22.3]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE187.2_C3-TESTIS_LASSOSUM_MGI_20200608
PPM001288 PGS000603 (PRSWEB_PHECODE187.2_GWAS-Catalog-r2019-05-03-X187.2_PT_MGI_20200608) PSS000553 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Malignant neoplasm of testis OR: 1.625 [1.27, 2.079]
β: 0.485 (0.126)
AUROC: 0.625 [0.557, 0.693] Nagelkerke's Pseudo-R²: 0.044
Brier score: 0.084
Odds Ratio (OR, top 1% vs. Rest): 6.05 [1.73, 21.2]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE187.2_GWAS-Catalog-r2019-05-03-X187.2_PT_MGI_20200608
PPM001292 PGS000607 (PRSWEB_PHECODE189.2_20001-1035_PRS-CS_MGI_20200608) PSS000555 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Cancer of bladder OR: 1.096 [1.018, 1.18]
β: 0.0918 (0.0377)
AUROC: 0.531 [0.509, 0.551] Nagelkerke's Pseudo-R²: 0.00156
Brier score: 0.0922
Odds Ratio (OR, top 1% vs. Rest): 0.671 [0.279, 1.61]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE189.2_20001-1035_PRS-CS_MGI_20200608
PPM001294 PGS000609 (PRSWEB_PHECODE189.2_C67_LASSOSUM_MGI_20200608) PSS000555 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Cancer of bladder OR: 1.106 [1.027, 1.191]
β: 0.101 (0.0376)
AUROC: 0.528 [0.508, 0.549] Nagelkerke's Pseudo-R²: 0.00205
Brier score: 0.0922
Odds Ratio (OR, top 1% vs. Rest): 1.69 [0.934, 3.06]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE189.2_C67_LASSOSUM_MGI_20200608
PPM001297 PGS000612 (PRSWEB_PHECODE189.2_GWAS-Catalog-r2019-05-03-X189.2_PT_MGI_20200608) PSS000555 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Cancer of bladder OR: 1.292 [1.201, 1.391]
β: 0.256 (0.0375)
AUROC: 0.572 [0.55, 0.594] Nagelkerke's Pseudo-R²: 0.013
Brier score: 0.0917
Odds Ratio (OR, top 1% vs. Rest): 1.47 [0.779, 2.77]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE189.2_GWAS-Catalog-r2019-05-03-X189.2_PT_MGI_20200608
PPM001300 PGS000615 (PRSWEB_PHECODE189.2_UKBB-SAIGE-HRC-X189.2_PT_MGI_20200608) PSS000555 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Cancer of bladder OR: 1.084 [1.007, 1.167]
β: 0.0809 (0.0376)
AUROC: 0.519 [0.498, 0.541] Nagelkerke's Pseudo-R²: 0.00137
Brier score: 0.0922
Odds Ratio (OR, top 1% vs. Rest): 0.788 [0.35, 1.78]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE189.2_UKBB-SAIGE-HRC-X189.2_PT_MGI_20200608
PPM001304 PGS000619 (PRSWEB_PHECODE191.1_GWAS-Catalog-r2019-05-03-X191.1_PT_UKB_20200608) PSS000578 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Cancer of brain and nervous system OR: 1.564 [1.396, 1.753]
β: 0.448 (0.0581)
AUROC: 0.622 [0.59, 0.653] Nagelkerke's Pseudo-R²: 0.0401
Brier score: 0.0812
Odds Ratio (OR, top 1% vs. Rest): 2.93 [1.34, 6.41]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE191.1_GWAS-Catalog-r2019-05-03-X191.1_PT_UKB_20200608
PPM001307 PGS000622 (PRSWEB_PHECODE191.11_GWAS-Catalog-r2019-05-03-X191.11_P_5e-08_UKB_20200608) PSS000577 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Cancer of brain OR: 1.486 [1.315, 1.679]
β: 0.396 (0.0624)
AUROC: 0.605 [0.569, 0.639] Nagelkerke's Pseudo-R²: 0.0289
Brier score: 0.0815
Odds Ratio (OR, top 1% vs. Rest): 3.38 [1.59, 7.2]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE191.11_GWAS-Catalog-r2019-05-03-X191.11_P_5e-08_UKB_20200608
PPM001310 PGS000625 (PRSWEB_PHECODE191.11_UKBB-SAIGE-HRC-X191.11_PT_MGI_20200608) PSS000557 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Cancer of brain OR: 1.142 [1.004, 1.299]
β: 0.133 (0.0657)
AUROC: 0.53 [0.492, 0.57] Nagelkerke's Pseudo-R²: 0.00328
Brier score: 0.0825
Odds Ratio (OR, top 1% vs. Rest): 2.28 [0.88, 5.88]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE191.11_UKBB-SAIGE-HRC-X191.11_PT_MGI_20200608
PPM001314 PGS000629 (PRSWEB_PHECODE193_C73_PT_MGI_20200608) PSS000558 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Thyroid cancer β: 0.114 (0.0517)
OR: 1.121 [1.013, 1.24]
AUROC: 0.52 [0.488, 0.55] Nagelkerke's Pseudo-R²: 0.00247
Brier score: 0.0827
Odds Ratio (OR, top 1% vs. Rest): 2.15 [1.01, 4.59]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE193_C73_PT_MGI_20200608
PPM001317 PGS000632 (PRSWEB_PHECODE193_GWAS-Catalog-r2019-05-03-X193_PT_MGI_20200608) PSS000558 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Thyroid cancer OR: 1.568 [1.412, 1.74]
β: 0.45 (0.0532)
AUROC: 0.618 [0.587, 0.647] Nagelkerke's Pseudo-R²: 0.0365
Brier score: 0.0812
Odds Ratio (OR, top 1% vs. Rest): 5.14 [2.94, 8.99]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE193_GWAS-Catalog-r2019-05-03-X193_PT_MGI_20200608
PPM001320 PGS000635 (PRSWEB_PHECODE193_UKBB-SAIGE-HRC-X193_PT_MGI_20200608) PSS000558 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Thyroid cancer OR: 1.315 [1.194, 1.448]
β: 0.274 (0.0492)
AUROC: 0.569 [0.538, 0.598] Nagelkerke's Pseudo-R²: 0.0151
Brier score: 0.0822
Odds Ratio (OR, top 1% vs. Rest): 1.65 [0.708, 3.83]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE193_UKBB-SAIGE-HRC-X193_PT_MGI_20200608
PPM001323 PGS000638 (PRSWEB_PHECODE201_GWAS-Catalog-r2019-05-03-X201_P_5e-08_MGI_20200608) PSS000559 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Hodgkin's disease OR: 1.377 [1.08, 1.755]
β: 0.32 (0.124)
AUROC: 0.601 [0.535, 0.671] Nagelkerke's Pseudo-R²: 0.0193
Brier score: 0.0824
Odds Ratio (OR, top 1% vs. Rest): 1.62 [0.258, 10.1]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE201_GWAS-Catalog-r2019-05-03-X201_P_5e-08_MGI_20200608
PPM001039 PGS000354 (PRSWEB_PHECODE10001_UKBB-SAIGE-HRC-X10001_PRS-CS_MGI_20200608) PSS000533 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Any Cancer OR: 1.079 [1.039, 1.119]
β: 0.0758 (0.0189)
AUROC: 0.521 [0.51, 0.532] Nagelkerke's Pseudo-R²: 0.00112
Brier score: 0.182
Odds Ratio (OR, top 1% vs. Rest): 1.27 [0.887, 1.81]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE10001_UKBB-SAIGE-HRC-X10001_PRS-CS_MGI_20200608
PPM001330 PGS000645 (PRSWEB_PHECODE204.1_C-LYMPHOID-LEUKAEMIA_PT_MGI_20200608) PSS000562 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Lymphoid leukemia OR: 1.358 [1.113, 1.657]
β: 0.306 (0.102)
AUROC: 0.578 [0.517, 0.642] Nagelkerke's Pseudo-R²: 0.0193
Brier score: 0.0819
Odds Ratio (OR, top 1% vs. Rest): 3.69 [1.01, 13.4]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE204.1_C-LYMPHOID-LEUKAEMIA_PT_MGI_20200608
PPM001333 PGS000648 (PRSWEB_PHECODE204.12_GWAS-Catalog-r2019-05-03-X204.12_PT_MGI_20200608) PSS000561 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Lymphoid leukemia, chronic OR: 2.124 [1.648, 2.738]
β: 0.753 (0.13)
AUROC: 0.696 [0.621, 0.764] Nagelkerke's Pseudo-R²: 0.102
Brier score: 0.0776
Odds Ratio (OR, top 1% vs. Rest): 12.9 [4.45, 37.6]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE204.12_GWAS-Catalog-r2019-05-03-X204.12_PT_MGI_20200608
PPM001336 PGS000651 (PRSWEB_PHECODE204.12_UKBB-SAIGE-HRC-X204.12_LASSOSUM_MGI_20200608) PSS000561 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Lymphoid leukemia, chronic OR: 1.32 [1.041, 1.675]
β: 0.278 (0.121)
AUROC: 0.573 [0.503, 0.644] Nagelkerke's Pseudo-R²: 0.0145
Brier score: 0.0823
Odds Ratio (OR, top 1% vs. Rest): 4.84 [1.23, 19.0]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE204.12_UKBB-SAIGE-HRC-X204.12_LASSOSUM_MGI_20200608
PPM001339 PGS000654 (PRSWEB_PHECODE204.4_GWAS-Catalog-r2019-05-03-X204.4_PT_UKB_20200608) PSS000582 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Multiple myeloma OR: 1.316 [1.156, 1.499]
β: 0.275 (0.0662)
AUROC: 0.576 [0.536, 0.616] Nagelkerke's Pseudo-R²: 0.0137
Brier score: 0.0818
Odds Ratio (OR, top 1% vs. Rest): 2.2 [0.854, 5.66]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE204.4_GWAS-Catalog-r2019-05-03-X204.4_PT_UKB_20200608
PPM001038 PGS000353 (PRSWEB_PHECODE10001_UKBB-SAIGE-HRC-X10001_P_5e-08_MGI_20200608) PSS000533 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Any Cancer OR: 1.08 [1.041, 1.122]
β: 0.0774 (0.0191)
AUROC: 0.515 [0.503, 0.526] Nagelkerke's Pseudo-R²: 0.00151
Brier score: 0.182
Odds Ratio (OR, top 1% vs. Rest): 1.48 [1.04, 2.1]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE10001_UKBB-SAIGE-HRC-X10001_P_5e-08_MGI_20200608
PPM001040 PGS000355 (PRSWEB_PHECODE10001_UKBB-SAIGE-HRC-X10001_PT_MGI_20200608) PSS000533 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Any Cancer OR: 1.084 [1.044, 1.125]
β: 0.0803 (0.0191)
AUROC: 0.517 [0.506, 0.527] Nagelkerke's Pseudo-R²: 0.00167
Brier score: 0.182
Odds Ratio (OR, top 1% vs. Rest): 1.42 [1.0, 2.02]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE10001_UKBB-SAIGE-HRC-X10001_PT_MGI_20200608
PPM001041 PGS000356 (PRSWEB_PHECODE10001_UKBB-SAIGE-HRC-X10001_LASSOSUM_MGI_20200608) PSS000533 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Any Cancer OR: 1.106 [1.065, 1.148]
β: 0.101 (0.0192)
AUROC: 0.523 [0.512, 0.535] Nagelkerke's Pseudo-R²: 0.00294
Brier score: 0.182
Odds Ratio (OR, top 1% vs. Rest): 1.61 [1.14, 2.27]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE10001_UKBB-SAIGE-HRC-X10001_LASSOSUM_MGI_20200608
PPM001043 PGS000358 (PRSWEB_PHECODE145_UKBB-SAIGE-HRC-X145_PRS-CS_MGI_20200608) PSS000535 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Cancer of mouth OR: 1.116 [1.024, 1.216]
β: 0.11 (0.0438)
AUROC: 0.528 [0.502, 0.552] Nagelkerke's Pseudo-R²: 0.00207
Brier score: 0.0829
Odds Ratio (OR, top 1% vs. Rest): 1.63 [0.812, 3.26]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE145_UKBB-SAIGE-HRC-X145_PRS-CS_MGI_20200608
PPM001044 PGS000359 (PRSWEB_PHECODE145.2_C3-TONGUENAS_PRS-CS_MGI_20200608) PSS000534 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Cancer of tongue OR: 1.142 [1.006, 1.297]
β: 0.133 (0.0647)
AUROC: 0.538 [0.501, 0.575] Nagelkerke's Pseudo-R²: 0.00325
Brier score: 0.0827
Odds Ratio (OR, top 1% vs. Rest): 1.69 [0.61, 4.71]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE145.2_C3-TONGUENAS_PRS-CS_MGI_20200608
PPM001046 PGS000361 (PRSWEB_PHECODE149.4_C3-LARYNX_LASSOSUM_MGI_20200608) PSS000536 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Cancer of larynx OR: 1.195 [1.014, 1.408]
β: 0.178 (0.0836)
AUROC: 0.55 [0.504, 0.593] Nagelkerke's Pseudo-R²: 0.00551
Brier score: 0.0824
Odds Ratio (OR, top 1% vs. Rest): 1.51 [0.382, 5.94]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE149.4_C3-LARYNX_LASSOSUM_MGI_20200608
PPM001047 PGS000362 (PRSWEB_PHECODE149.4_UKBB-SAIGE-HRC-X149.4_PT_MGI_20200608) PSS000536 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Cancer of larynx OR: 1.195 [1.023, 1.396]
β: 0.178 (0.0793)
AUROC: 0.543 [0.494, 0.59] Nagelkerke's Pseudo-R²: 0.00609
Brier score: 0.0824
Odds Ratio (OR, top 1% vs. Rest): 1.52 [0.384, 5.98]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE149.4_UKBB-SAIGE-HRC-X149.4_PT_MGI_20200608
PPM001049 PGS000364 (PRSWEB_PHECODE150_C15_LASSOSUM_MGI_20200608) PSS000537 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Cancer of esophagus OR: 1.203 [1.041, 1.391]
β: 0.185 (0.074)
AUROC: 0.551 [0.51, 0.588] Nagelkerke's Pseudo-R²: 0.00648
Brier score: 0.0826
Odds Ratio (OR, top 1% vs. Rest): 1.81 [0.56, 5.82]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE150_C15_LASSOSUM_MGI_20200608
PPM001050 PGS000365 (PRSWEB_PHECODE150_C3-OESOPHAGUS_PRS-CS_MGI_20200608) PSS000537 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Cancer of esophagus OR: 1.187 [1.021, 1.38]
β: 0.171 (0.0769)
AUROC: 0.553 [0.514, 0.596] Nagelkerke's Pseudo-R²: 0.00521
Brier score: 0.0826
Odds Ratio (OR, top 1% vs. Rest): 1.27 [0.329, 4.9]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE150_C3-OESOPHAGUS_PRS-CS_MGI_20200608
PPM001052 PGS000367 (PRSWEB_PHECODE153_CRC-Huyghe_P_5e-08_MGI_20200608) PSS000540 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Colorectal cancer OR: 1.198 [1.102, 1.302]
β: 0.181 (0.0425)
AUROC: 0.55 [0.522, 0.574] Nagelkerke's Pseudo-R²: 0.00586
Brier score: 0.0828
Odds Ratio (OR, top 1% vs. Rest): 2.2 [1.21, 4.0]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE153_CRC-Huyghe_P_5e-08_MGI_20200608
PPM001053 PGS000368 (PRSWEB_PHECODE153_CRC-Huyghe_P_5e-08_UKB_20200608) PSS000564 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Colorectal cancer OR: 1.516 [1.451, 1.585]
β: 0.416 (0.0225)
AUROC: 0.612 [0.6, 0.625] Nagelkerke's Pseudo-R²: 0.0304
Brier score: 0.0813
Odds Ratio (OR, top 1% vs. Rest): 3.85 [2.99, 4.96]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE153_CRC-Huyghe_P_5e-08_UKB_20200608
PPM001055 PGS000370 (PRSWEB_PHECODE153_CRC-Huyghe_PT_UKB_20200608) PSS000564 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Colorectal cancer OR: 1.547 [1.48, 1.617]
β: 0.436 (0.0226)
AUROC: 0.617 [0.605, 0.63] Nagelkerke's Pseudo-R²: 0.0332
Brier score: 0.0812
Odds Ratio (OR, top 1% vs. Rest): 4.0 [3.11, 5.13]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE153_CRC-Huyghe_PT_UKB_20200608
PPM001056 PGS000371 (PRSWEB_PHECODE153_GWAS-Catalog-r2019-05-03-X153_P_5e-08_UKB_20200608) PSS000564 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Colorectal cancer OR: 1.254 [1.202, 1.309]
β: 0.226 (0.0217)
AUROC: 0.561 [0.548, 0.573] Nagelkerke's Pseudo-R²: 0.00946
Brier score: 0.0822
Odds Ratio (OR, top 1% vs. Rest): 1.79 [1.28, 2.51]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE153_GWAS-Catalog-r2019-05-03-X153_P_5e-08_UKB_20200608
PPM001058 PGS000373 (PRSWEB_PHECODE153_UKBB-SAIGE-HRC-X153_PRS-CS_MGI_20200608) PSS000540 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Colorectal cancer OR: 1.189 [1.093, 1.293]
β: 0.173 (0.0428)
AUROC: 0.548 [0.523, 0.572] Nagelkerke's Pseudo-R²: 0.00529
Brier score: 0.0829
Odds Ratio (OR, top 1% vs. Rest): 1.71 [0.882, 3.33]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE153_UKBB-SAIGE-HRC-X153_PRS-CS_MGI_20200608
PPM001060 PGS000375 (PRSWEB_PHECODE153_UKBB-SAIGE-HRC-X153_LASSOSUM_MGI_20200608) PSS000540 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Colorectal cancer OR: 1.113 [1.024, 1.21]
β: 0.107 (0.0425)
AUROC: 0.53 [0.503, 0.555] Nagelkerke's Pseudo-R²: 0.00205
Brier score: 0.083
Odds Ratio (OR, top 1% vs. Rest): 2.76 [1.59, 4.81]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE153_UKBB-SAIGE-HRC-X153_LASSOSUM_MGI_20200608
PPM001062 PGS000377 (PRSWEB_PHECODE153.2_C18_LASSOSUM_MGI_20200608) PSS000538 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Colon cancer OR: 1.174 [1.066, 1.292]
β: 0.16 (0.049)
AUROC: 0.545 [0.518, 0.574] Nagelkerke's Pseudo-R²: 0.00441
Brier score: 0.0831
Odds Ratio (OR, top 1% vs. Rest): 1.4 [0.607, 3.22]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE153.2_C18_LASSOSUM_MGI_20200608
PPM001064 PGS000379 (PRSWEB_PHECODE153.2_C3-COLON_LASSOSUM_MGI_20200608) PSS000538 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Colon cancer OR: 1.143 [1.038, 1.258]
β: 0.134 (0.049)
AUROC: 0.536 [0.51, 0.567] Nagelkerke's Pseudo-R²: 0.00302
Brier score: 0.0832
Odds Ratio (OR, top 1% vs. Rest): 0.757 [0.252, 2.28]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE153.2_C3-COLON_LASSOSUM_MGI_20200608
PPM001065 PGS000380 (PRSWEB_PHECODE153.2_UKBB-SAIGE-HRC-X153.2_PRS-CS_MGI_20200608) PSS000538 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Colon cancer OR: 1.324 [1.203, 1.457]
β: 0.281 (0.0489)
AUROC: 0.569 [0.539, 0.599] Nagelkerke's Pseudo-R²: 0.0138
Brier score: 0.0827
Odds Ratio (OR, top 1% vs. Rest): 3.85 [2.19, 6.77]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE153.2_UKBB-SAIGE-HRC-X153.2_PRS-CS_MGI_20200608
PPM001066 PGS000381 (PRSWEB_PHECODE153.2_UKBB-SAIGE-HRC-X153.2_PT_MGI_20200608) PSS000538 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Colon cancer OR: 1.212 [1.105, 1.33]
β: 0.193 (0.0472)
AUROC: 0.55 [0.522, 0.577] Nagelkerke's Pseudo-R²: 0.00703
Brier score: 0.0831
Odds Ratio (OR, top 1% vs. Rest): 1.6 [0.733, 3.51]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE153.2_UKBB-SAIGE-HRC-X153.2_PT_MGI_20200608
PPM001068 PGS000383 (PRSWEB_PHECODE153.3_C19_PRS-CS_MGI_20200608) PSS000539 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Malignant neoplasm of rectum, rectosigmoid junction, and anus OR: 1.126 [1.005, 1.262]
β: 0.119 (0.0579)
AUROC: 0.533 [0.5, 0.567] Nagelkerke's Pseudo-R²: 0.00257
Brier score: 0.0829
Odds Ratio (OR, top 1% vs. Rest): 1.34 [0.491, 3.65]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE153.3_C19_PRS-CS_MGI_20200608
PPM001071 PGS000386 (PRSWEB_PHECODE157_GWAS-Catalog-r2019-05-03-X157_PT_UKB_20200608) PSS000565 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Pancreatic cancer OR: 1.342 [1.199, 1.503]
β: 0.294 (0.0577)
AUROC: 0.579 [0.548, 0.611] Nagelkerke's Pseudo-R²: 0.0157
Brier score: 0.0822
Odds Ratio (OR, top 1% vs. Rest): 1.64 [0.655, 4.12]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE157_GWAS-Catalog-r2019-05-03-X157_PT_UKB_20200608
PPM001072 PGS000387 (PRSWEB_PHECODE165_UKBB-SAIGE-HRC-X165_LASSOSUM_MGI_20200608) PSS000542 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Cancer within the respiratory system OR: 1.109 [1.008, 1.22]
β: 0.103 (0.0486)
AUROC: 0.53 [0.502, 0.557] Nagelkerke's Pseudo-R²: 0.0018
Brier score: 0.0826
Odds Ratio (OR, top 1% vs. Rest): 2.22 [1.12, 4.37]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE165_UKBB-SAIGE-HRC-X165_LASSOSUM_MGI_20200608
PPM001074 PGS000389 (PRSWEB_PHECODE165.1_GWAS-Catalog-r2019-05-03-X165.1_P_5e-08_MGI_20200608) PSS000541 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Cancer of bronchus; lung OR: 1.11 [1.006, 1.225]
β: 0.105 (0.0501)
AUROC: 0.52 [0.492, 0.547] Nagelkerke's Pseudo-R²: 0.00202
Brier score: 0.0827
Odds Ratio (OR, top 1% vs. Rest): 2.19 [1.07, 4.49]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE165.1_GWAS-Catalog-r2019-05-03-X165.1_P_5e-08_MGI_20200608
PPM001075 PGS000390 (PRSWEB_PHECODE165.1_GWAS-Catalog-r2019-05-03-X165.1_P_5e-08_UKB_20200608) PSS000566 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Cancer of bronchus; lung OR: 1.194 [1.124, 1.269]
β: 0.178 (0.0309)
AUROC: 0.543 [0.526, 0.562] Nagelkerke's Pseudo-R²: 0.00583
Brier score: 0.0824
Odds Ratio (OR, top 1% vs. Rest): 0.852 [0.437, 1.66]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE165.1_GWAS-Catalog-r2019-05-03-X165.1_P_5e-08_UKB_20200608
PPM001077 PGS000392 (PRSWEB_PHECODE165.1_GWAS-Catalog-r2019-05-03-X165.1_PT_UKB_20200608) PSS000566 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Cancer of bronchus; lung OR: 1.221 [1.149, 1.298]
β: 0.2 (0.0313)
AUROC: 0.552 [0.534, 0.569] Nagelkerke's Pseudo-R²: 0.00728
Brier score: 0.0824
Odds Ratio (OR, top 1% vs. Rest): 1.94 [1.22, 3.1]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE165.1_GWAS-Catalog-r2019-05-03-X165.1_PT_UKB_20200608
PPM001078 PGS000393 (PRSWEB_PHECODE165.1_LUNG-CANCER_PRS-CS_MGI_20200608) PSS000541 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Cancer of bronchus; lung OR: 1.149 [1.04, 1.269]
β: 0.139 (0.0509)
AUROC: 0.539 [0.508, 0.568] Nagelkerke's Pseudo-R²: 0.00329
Brier score: 0.0826
Odds Ratio (OR, top 1% vs. Rest): 2.18 [1.06, 4.46]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE165.1_LUNG-CANCER_PRS-CS_MGI_20200608
PPM001080 PGS000395 (PRSWEB_PHECODE165.1_UKBB-SAIGE-HRC-X165.1_PRS-CS_MGI_20200608) PSS000541 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Cancer of bronchus; lung OR: 1.133 [1.025, 1.252]
β: 0.125 (0.051)
AUROC: 0.533 [0.505, 0.562] Nagelkerke's Pseudo-R²: 0.00277
Brier score: 0.0827
Odds Ratio (OR, top 1% vs. Rest): 1.27 [0.514, 3.12]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE165.1_UKBB-SAIGE-HRC-X165.1_PRS-CS_MGI_20200608
PPM001081 PGS000396 (PRSWEB_PHECODE165.1_UKBB-SAIGE-HRC-X165.1_PT_MGI_20200608) PSS000541 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Cancer of bronchus; lung OR: 1.121 [1.015, 1.238]
β: 0.114 (0.0507)
AUROC: 0.525 [0.496, 0.554] Nagelkerke's Pseudo-R²: 0.00233
Brier score: 0.0827
Odds Ratio (OR, top 1% vs. Rest): 2.21 [1.08, 4.51]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE165.1_UKBB-SAIGE-HRC-X165.1_PT_MGI_20200608
PPM001083 PGS000398 (PRSWEB_PHECODE172_20001-1003_PRS-CS_MGI_20200608) PSS000548 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Skin cancer OR: 1.042 [1.003, 1.082]
β: 0.0407 (0.0195)
AUROC: 0.51 [0.499, 0.521] Nagelkerke's Pseudo-R²: 0.00028
Brier score: 0.148
Odds Ratio (OR, top 1% vs. Rest): 1.7 [1.22, 2.38]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE172_20001-1003_PRS-CS_MGI_20200608
PPM001084 PGS000399 (PRSWEB_PHECODE172_20001-1003_PT_MGI_20200608) PSS000548 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Skin cancer OR: 1.158 [1.116, 1.202]
β: 0.147 (0.0189)
AUROC: 0.513 [0.503, 0.523] Nagelkerke's Pseudo-R²: 0.00545
Brier score: 0.148
Odds Ratio (OR, top 1% vs. Rest): 1.56 [1.12, 2.16]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE172_20001-1003_PT_MGI_20200608
PPM001086 PGS000401 (PRSWEB_PHECODE172_C3-SKIN_PRS-CS_MGI_20200608) PSS000548 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Skin cancer OR: 1.342 [1.291, 1.396]
β: 0.294 (0.0199)
AUROC: 0.581 [0.57, 0.591] Nagelkerke's Pseudo-R²: 0.0202
Brier score: 0.146
Odds Ratio (OR, top 1% vs. Rest): 2.25 [1.67, 3.03]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE172_C3-SKIN_PRS-CS_MGI_20200608
PPM001087 PGS000402 (PRSWEB_PHECODE172_C3-SKIN_PT_MGI_20200608) PSS000548 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Skin cancer OR: 1.366 [1.314, 1.421]
β: 0.312 (0.0198)
AUROC: 0.586 [0.576, 0.597] Nagelkerke's Pseudo-R²: 0.0224
Brier score: 0.146
Odds Ratio (OR, top 1% vs. Rest): 2.23 [1.64, 3.03]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE172_C3-SKIN_PT_MGI_20200608
PPM001089 PGS000404 (PRSWEB_PHECODE172_UKBB-SAIGE-HRC-X172_P_5e-08_MGI_20200608) PSS000548 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Skin cancer OR: 1.369 [1.317, 1.422]
β: 0.314 (0.0196)
AUROC: 0.584 [0.574, 0.594] Nagelkerke's Pseudo-R²: 0.0226
Brier score: 0.146
Odds Ratio (OR, top 1% vs. Rest): 2.3 [1.72, 3.09]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE172_UKBB-SAIGE-HRC-X172_P_5e-08_MGI_20200608
PPM001090 PGS000405 (PRSWEB_PHECODE172_UKBB-SAIGE-HRC-X172_PRS-CS_MGI_20200608) PSS000548 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Skin cancer OR: 1.338 [1.287, 1.391]
β: 0.291 (0.0199)
AUROC: 0.58 [0.57, 0.591] Nagelkerke's Pseudo-R²: 0.0192
Brier score: 0.146
Odds Ratio (OR, top 1% vs. Rest): 2.42 [1.81, 3.24]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE172_UKBB-SAIGE-HRC-X172_PRS-CS_MGI_20200608
PPM001092 PGS000407 (PRSWEB_PHECODE172_UKBB-SAIGE-HRC-X172_LASSOSUM_MGI_20200608) PSS000548 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Skin cancer OR: 1.38 [1.328, 1.434]
β: 0.322 (0.0197)
AUROC: 0.586 [0.575, 0.597] Nagelkerke's Pseudo-R²: 0.0245
Brier score: 0.146
Odds Ratio (OR, top 1% vs. Rest): 2.26 [1.69, 3.03]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE172_UKBB-SAIGE-HRC-X172_LASSOSUM_MGI_20200608
PPM001093 PGS000408 (PRSWEB_PHECODE172.1_20001-1059_P_5e-08_MGI_20200608) PSS000543 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Melanomas of skin, dx or hx OR: 1.384 [1.311, 1.461]
β: 0.325 (0.0276)
AUROC: 0.576 [0.561, 0.593] Nagelkerke's Pseudo-R²: 0.0217
Brier score: 0.0957
Odds Ratio (OR, top 1% vs. Rest): 2.25 [1.48, 3.42]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE172.1_20001-1059_P_5e-08_MGI_20200608
PPM001096 PGS000411 (PRSWEB_PHECODE172.1_20001-1059_LASSOSUM_MGI_20200608) PSS000543 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Melanomas of skin, dx or hx OR: 1.378 [1.308, 1.451]
β: 0.32 (0.0265)
AUROC: 0.571 [0.555, 0.587] Nagelkerke's Pseudo-R²: 0.0222
Brier score: 0.0957
Odds Ratio (OR, top 1% vs. Rest): 2.0 [1.29, 3.09]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE172.1_20001-1059_LASSOSUM_MGI_20200608
PPM001099 PGS000414 (PRSWEB_PHECODE172.1_C3-MELANOMA-SKIN_PT_MGI_20200608) PSS000543 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Melanomas of skin, dx or hx OR: 1.44 [1.363, 1.522]
β: 0.365 (0.0283)
AUROC: 0.593 [0.576, 0.609] Nagelkerke's Pseudo-R²: 0.026
Brier score: 0.0954
Odds Ratio (OR, top 1% vs. Rest): 2.97 [2.02, 4.36]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE172.1_C3-MELANOMA-SKIN_PT_MGI_20200608
PPM001100 PGS000415 (PRSWEB_PHECODE172.1_C3-MELANOMA-SKIN_LASSOSUM_MGI_20200608) PSS000543 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Melanomas of skin, dx or hx OR: 1.391 [1.318, 1.467]
β: 0.33 (0.0272)
AUROC: 0.578 [0.562, 0.595] Nagelkerke's Pseudo-R²: 0.0227
Brier score: 0.0957
Odds Ratio (OR, top 1% vs. Rest): 2.34 [1.55, 3.53]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE172.1_C3-MELANOMA-SKIN_LASSOSUM_MGI_20200608
PPM001102 PGS000417 (PRSWEB_PHECODE172.1_C43_PRS-CS_MGI_20200608) PSS000543 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Melanomas of skin, dx or hx OR: 1.228 [1.159, 1.3]
β: 0.205 (0.0294)
AUROC: 0.556 [0.541, 0.571] Nagelkerke's Pseudo-R²: 0.00812
Brier score: 0.0965
Odds Ratio (OR, top 1% vs. Rest): 1.88 [1.2, 2.95]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE172.1_C43_PRS-CS_MGI_20200608
PPM001104 PGS000419 (PRSWEB_PHECODE172.1_C43_LASSOSUM_MGI_20200608) PSS000543 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Melanomas of skin, dx or hx OR: 1.348 [1.279, 1.421]
β: 0.299 (0.0268)
AUROC: 0.565 [0.549, 0.583] Nagelkerke's Pseudo-R²: 0.0188
Brier score: 0.0959
Odds Ratio (OR, top 1% vs. Rest): 1.93 [1.24, 3.0]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE172.1_C43_LASSOSUM_MGI_20200608
PPM001105 PGS000420 (PRSWEB_PHECODE172.1_D03_PT_MGI_20200608) PSS000543 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Melanomas of skin, dx or hx OR: 1.066 [1.007, 1.128]
β: 0.0639 (0.029)
AUROC: 0.516 [0.5, 0.533] Nagelkerke's Pseudo-R²: 0.00074
Brier score: 0.0969
Odds Ratio (OR, top 1% vs. Rest): 1.07 [0.603, 1.9]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE172.1_D03_PT_MGI_20200608
PPM001107 PGS000422 (PRSWEB_PHECODE172.1_GWAS-Catalog-r2019-05-03-X172.1_P_5e-08_UKB_20200608) PSS000567 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Melanomas of skin, dx or hx OR: 1.539 [1.454, 1.629]
β: 0.431 (0.029)
AUROC: 0.615 [0.599, 0.63] Nagelkerke's Pseudo-R²: 0.0332
Brier score: 0.0813
Odds Ratio (OR, top 1% vs. Rest): 2.57 [1.75, 3.77]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE172.1_GWAS-Catalog-r2019-05-03-X172.1_P_5e-08_UKB_20200608
PPM001108 PGS000423 (PRSWEB_PHECODE172.1_GWAS-Catalog-r2019-05-03-X172.1_PT_MGI_20200608) PSS000543 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Melanomas of skin, dx or hx β: 0.394 (0.0301)
OR: 1.484 [1.399, 1.574]
AUROC: 0.608 [0.592, 0.623] Nagelkerke's Pseudo-R²: 0.0289
Brier score: 0.0954
Odds Ratio (OR, top 1% vs. Rest): 2.93 [2.0, 4.3]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE172.1_GWAS-Catalog-r2019-05-03-X172.1_PT_MGI_20200608
PPM001109 PGS000424 (PRSWEB_PHECODE172.1_GWAS-Catalog-r2019-05-03-X172.1_PT_UKB_20200608) PSS000567 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Melanomas of skin, dx or hx OR: 1.563 [1.475, 1.656]
β: 0.447 (0.0294)
AUROC: 0.619 [0.603, 0.634] Nagelkerke's Pseudo-R²: 0.035
Brier score: 0.0812
Odds Ratio (OR, top 1% vs. Rest): 3.12 [2.18, 4.47]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE172.1_GWAS-Catalog-r2019-05-03-X172.1_PT_UKB_20200608
PPM001111 PGS000426 (PRSWEB_PHECODE172.1_Melanoma-Ransohoff_P_5e-08_UKB_20200608) PSS000567 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Melanomas of skin, dx or hx OR: 1.551 [1.463, 1.643]
β: 0.439 (0.0296)
AUROC: 0.62 [0.604, 0.635] Nagelkerke's Pseudo-R²: 0.0335
Brier score: 0.0813
Odds Ratio (OR, top 1% vs. Rest): 2.81 [1.93, 4.07]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE172.1_Melanoma-Ransohoff_P_5e-08_UKB_20200608
PPM001112 PGS000427 (PRSWEB_PHECODE172.1_Melanoma-Ransohoff_PT_MGI_20200608) PSS000543 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Melanomas of skin, dx or hx OR: 1.453 [1.369, 1.542]
β: 0.374 (0.0304)
AUROC: 0.601 [0.585, 0.617] Nagelkerke's Pseudo-R²: 0.0255
Brier score: 0.0955
Odds Ratio (OR, top 1% vs. Rest): 2.54 [1.7, 3.8]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE172.1_Melanoma-Ransohoff_PT_MGI_20200608
PPM001113 PGS000428 (PRSWEB_PHECODE172.1_Melanoma-Ransohoff_PT_UKB_20200608) PSS000567 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Melanomas of skin, dx or hx OR: 1.551 [1.463, 1.643]
β: 0.439 (0.0296)
AUROC: 0.62 [0.604, 0.635] Nagelkerke's Pseudo-R²: 0.0335
Brier score: 0.0813
Odds Ratio (OR, top 1% vs. Rest): 2.81 [1.93, 4.07]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE172.1_Melanoma-Ransohoff_PT_UKB_20200608
PPM001114 PGS000429 (PRSWEB_PHECODE172.1_UKBB-SAIGE-HRC-X172.1_P_5e-08_MGI_20200608) PSS000543 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Melanomas of skin, dx or hx OR: 1.503 [1.422, 1.589]
β: 0.408 (0.0284)
AUROC: 0.606 [0.591, 0.622] Nagelkerke's Pseudo-R²: 0.0332
Brier score: 0.0951
Odds Ratio (OR, top 1% vs. Rest): 2.62 [1.77, 3.88]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE172.1_UKBB-SAIGE-HRC-X172.1_P_5e-08_MGI_20200608
PPM001116 PGS000431 (PRSWEB_PHECODE172.1_UKBB-SAIGE-HRC-X172.1_PT_MGI_20200608) PSS000543 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Melanomas of skin, dx or hx OR: 1.486 [1.405, 1.571]
β: 0.396 (0.0285)
AUROC: 0.604 [0.587, 0.62] Nagelkerke's Pseudo-R²: 0.0312
Brier score: 0.0952
Odds Ratio (OR, top 1% vs. Rest): 2.97 [2.04, 4.34]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE172.1_UKBB-SAIGE-HRC-X172.1_PT_MGI_20200608
PPM001117 PGS000432 (PRSWEB_PHECODE172.1_UKBB-SAIGE-HRC-X172.1_LASSOSUM_MGI_20200608) PSS000543 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Melanomas of skin, dx or hx OR: 1.391 [1.318, 1.467]
β: 0.33 (0.0273)
AUROC: 0.582 [0.566, 0.599] Nagelkerke's Pseudo-R²: 0.0228
Brier score: 0.0957
Odds Ratio (OR, top 1% vs. Rest): 1.99 [1.29, 3.07]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE172.1_UKBB-SAIGE-HRC-X172.1_LASSOSUM_MGI_20200608
PPM001119 PGS000434 (PRSWEB_PHECODE172.2_C3-OTHER-SKIN_PRS-CS_MGI_20200608) PSS000546 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Other non-epithelial cancer of skin OR: 1.361 [1.304, 1.42]
β: 0.308 (0.0217)
AUROC: 0.586 [0.573, 0.598] Nagelkerke's Pseudo-R²: 0.0208
Brier score: 0.137
Odds Ratio (OR, top 1% vs. Rest): 1.99 [1.43, 2.78]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE172.2_C3-OTHER-SKIN_PRS-CS_MGI_20200608
PPM001120 PGS000435 (PRSWEB_PHECODE172.2_C3-OTHER-SKIN_PT_MGI_20200608) PSS000546 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Other non-epithelial cancer of skin OR: 1.357 [1.301, 1.415]
β: 0.305 (0.0215)
AUROC: 0.584 [0.572, 0.597] Nagelkerke's Pseudo-R²: 0.0201
Brier score: 0.137
Odds Ratio (OR, top 1% vs. Rest): 2.7 [1.99, 3.66]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE172.2_C3-OTHER-SKIN_PT_MGI_20200608
PPM001122 PGS000437 (PRSWEB_PHECODE172.2_C44_P_5e-08_MGI_20200608) PSS000546 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Other non-epithelial cancer of skin OR: 1.352 [1.296, 1.409]
β: 0.301 (0.0213)
AUROC: 0.579 [0.566, 0.592] Nagelkerke's Pseudo-R²: 0.0206
Brier score: 0.137
Odds Ratio (OR, top 1% vs. Rest): 2.21 [1.6, 3.06]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE172.2_C44_P_5e-08_MGI_20200608
PPM001123 PGS000438 (PRSWEB_PHECODE172.2_C44_PRS-CS_MGI_20200608) PSS000546 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Other non-epithelial cancer of skin OR: 1.31 [1.256, 1.367]
β: 0.27 (0.0216)
AUROC: 0.575 [0.562, 0.587] Nagelkerke's Pseudo-R²: 0.0162
Brier score: 0.137
Odds Ratio (OR, top 1% vs. Rest): 1.79 [1.28, 2.51]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE172.2_C44_PRS-CS_MGI_20200608
PPM001125 PGS000440 (PRSWEB_PHECODE172.2_C44_LASSOSUM_MGI_20200608) PSS000546 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Other non-epithelial cancer of skin OR: 1.351 [1.296, 1.409]
β: 0.301 (0.0215)
AUROC: 0.581 [0.569, 0.592] Nagelkerke's Pseudo-R²: 0.0201
Brier score: 0.137
Odds Ratio (OR, top 1% vs. Rest): 2.55 [1.87, 3.46]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE172.2_C44_LASSOSUM_MGI_20200608
PPM001126 PGS000441 (PRSWEB_PHECODE172.2_UKBB-SAIGE-HRC-X172.2_P_5e-08_MGI_20200608) PSS000546 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Other non-epithelial cancer of skin OR: 1.39 [1.333, 1.449]
β: 0.329 (0.0214)
AUROC: 0.586 [0.574, 0.599] Nagelkerke's Pseudo-R²: 0.0241
Brier score: 0.136
Odds Ratio (OR, top 1% vs. Rest): 2.65 [1.94, 3.62]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE172.2_UKBB-SAIGE-HRC-X172.2_P_5e-08_MGI_20200608
PPM001128 PGS000443 (PRSWEB_PHECODE172.2_UKBB-SAIGE-HRC-X172.2_PT_MGI_20200608) PSS000546 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Other non-epithelial cancer of skin OR: 1.41 [1.352, 1.471]
β: 0.344 (0.0216)
AUROC: 0.591 [0.579, 0.603] Nagelkerke's Pseudo-R²: 0.0259
Brier score: 0.136
Odds Ratio (OR, top 1% vs. Rest): 2.89 [2.14, 3.92]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE172.2_UKBB-SAIGE-HRC-X172.2_PT_MGI_20200608
PPM001131 PGS000446 (PRSWEB_PHECODE172.21_20001-1061_PRS-CS_MGI_20200608) PSS000544 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Basal cell carcinoma OR: 1.291 [1.221, 1.366]
β: 0.256 (0.0286)
AUROC: 0.575 [0.559, 0.591] Nagelkerke's Pseudo-R²: 0.0139
Brier score: 0.109
Odds Ratio (OR, top 1% vs. Rest): 1.42 [0.871, 2.33]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE172.21_20001-1061_PRS-CS_MGI_20200608
PPM001133 PGS000448 (PRSWEB_PHECODE172.21_20001-1061_LASSOSUM_MGI_20200608) PSS000544 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Basal cell carcinoma OR: 1.411 [1.335, 1.491]
β: 0.344 (0.0282)
AUROC: 0.587 [0.57, 0.604] Nagelkerke's Pseudo-R²: 0.0254
Brier score: 0.108
Odds Ratio (OR, top 1% vs. Rest): 2.93 [2.03, 4.25]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE172.21_20001-1061_LASSOSUM_MGI_20200608
PPM001134 PGS000449 (PRSWEB_PHECODE172.21_20001-1073_PRS-CS_MGI_20200608) PSS000544 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Basal cell carcinoma OR: 1.093 [1.034, 1.155]
β: 0.0888 (0.0282)
AUROC: 0.525 [0.509, 0.54] Nagelkerke's Pseudo-R²: 0.00141
Brier score: 0.109
Odds Ratio (OR, top 1% vs. Rest): 1.65 [1.04, 2.61]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE172.21_20001-1073_PRS-CS_MGI_20200608
PPM001136 PGS000451 (PRSWEB_PHECODE172.21_20001-1073_LASSOSUM_MGI_20200608) PSS000544 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Basal cell carcinoma OR: 1.144 [1.084, 1.208]
β: 0.135 (0.0278)
AUROC: 0.521 [0.506, 0.536] Nagelkerke's Pseudo-R²: 0.00396
Brier score: 0.109
Odds Ratio (OR, top 1% vs. Rest): 2.44 [1.65, 3.62]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE172.21_20001-1073_LASSOSUM_MGI_20200608
PPM001137 PGS000452 (PRSWEB_PHECODE172.21_BCC-Chahal_P_5e-08_MGI_20200608) PSS000544 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Basal cell carcinoma OR: 1.663 [1.57, 1.761]
β: 0.508 (0.0293)
AUROC: 0.632 [0.616, 0.647] Nagelkerke's Pseudo-R²: 0.0487
Brier score: 0.106
Odds Ratio (OR, top 1% vs. Rest): 3.61 [2.53, 5.15]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE172.21_BCC-Chahal_P_5e-08_MGI_20200608
PPM001139 PGS000454 (PRSWEB_PHECODE172.21_BCC-Chahal_PT_MGI_20200608) PSS000544 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Basal cell carcinoma OR: 1.661 [1.568, 1.759]
β: 0.507 (0.0293)
AUROC: 0.632 [0.616, 0.647] Nagelkerke's Pseudo-R²: 0.0489
Brier score: 0.106
Odds Ratio (OR, top 1% vs. Rest): 3.79 [2.68, 5.35]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE172.21_BCC-Chahal_PT_MGI_20200608
PPM001140 PGS000455 (PRSWEB_PHECODE172.21_BCC-Chahal_PT_UKB_20200608) PSS000568 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Basal cell carcinoma OR: 1.511 [1.47, 1.554]
β: 0.413 (0.0142)
AUROC: 0.611 [0.604, 0.619] Nagelkerke's Pseudo-R²: 0.0301
Brier score: 0.0813
Odds Ratio (OR, top 1% vs. Rest): 2.8 [2.33, 3.36]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE172.21_BCC-Chahal_PT_UKB_20200608
PPM001141 PGS000456 (PRSWEB_PHECODE172.21_GWAS-Catalog-r2019-05-03-X172.21_P_5e-08_MGI_20200608) PSS000544 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Basal cell carcinoma OR: 1.633 [1.541, 1.729]
β: 0.49 (0.0293)
AUROC: 0.63 [0.615, 0.646] Nagelkerke's Pseudo-R²: 0.0456
Brier score: 0.106
Odds Ratio (OR, top 1% vs. Rest): 3.95 [2.79, 5.58]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE172.21_GWAS-Catalog-r2019-05-03-X172.21_P_5e-08_MGI_20200608
PPM001143 PGS000458 (PRSWEB_PHECODE172.21_GWAS-Catalog-r2019-05-03-X172.21_PT_MGI_20200608) PSS000544 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Basal cell carcinoma OR: 1.634 [1.542, 1.732]
β: 0.491 (0.0296)
AUROC: 0.628 [0.612, 0.644] Nagelkerke's Pseudo-R²: 0.0457
Brier score: 0.106
Odds Ratio (OR, top 1% vs. Rest): 4.03 [2.86, 5.69]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE172.21_GWAS-Catalog-r2019-05-03-X172.21_PT_MGI_20200608
PPM001144 PGS000459 (PRSWEB_PHECODE172.21_GWAS-Catalog-r2019-05-03-X172.21_PT_UKB_20200608) PSS000568 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Basal cell carcinoma OR: 1.528 [1.485, 1.572]
β: 0.424 (0.0144)
AUROC: 0.615 [0.608, 0.623] Nagelkerke's Pseudo-R²: 0.0314
Brier score: 0.0813
Odds Ratio (OR, top 1% vs. Rest): 3.05 [2.55, 3.64]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE172.21_GWAS-Catalog-r2019-05-03-X172.21_PT_UKB_20200608
PPM001146 PGS000461 (PRSWEB_PHECODE172.22_GWAS-Catalog-r2019-05-03-X172.22_P_5e-08_MGI_20200608) PSS000545 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Squamous cell carcinoma OR: 1.491 [1.395, 1.593]
β: 0.4 (0.0338)
AUROC: 0.599 [0.579, 0.618] Nagelkerke's Pseudo-R²: 0.0304
Brier score: 0.0974
Odds Ratio (OR, top 1% vs. Rest): 3.51 [2.29, 5.39]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE172.22_GWAS-Catalog-r2019-05-03-X172.22_P_5e-08_MGI_20200608
PPM001147 PGS000462 (PRSWEB_PHECODE172.22_GWAS-Catalog-r2019-05-03-X172.22_P_5e-08_UKB_20200608) PSS000569 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Squamous cell carcinoma OR: 1.324 [1.288, 1.361]
β: 0.28 (0.014)
AUROC: 0.573 [0.564, 0.58] Nagelkerke's Pseudo-R²: 0.0141
Brier score: 0.082
Odds Ratio (OR, top 1% vs. Rest): 2.13 [1.74, 2.61]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE172.22_GWAS-Catalog-r2019-05-03-X172.22_P_5e-08_UKB_20200608
PPM001261 PGS000576 (PRSWEB_PHECODE185_C61_LASSOSUM_MGI_20200608) PSS000552 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Cancer of prostate OR: 1.489 [1.39, 1.596]
β: 0.398 (0.0353)
AUROC: 0.607 [0.589, 0.627] Nagelkerke's Pseudo-R²: 0.0358
Brier score: 0.151
Odds Ratio (OR, top 1% vs. Rest): 2.46 [1.5, 4.01]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE185_C61_LASSOSUM_MGI_20200608
PPM001149 PGS000464 (PRSWEB_PHECODE172.22_GWAS-Catalog-r2019-05-03-X172.22_PT_UKB_20200608) PSS000569 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Squamous cell carcinoma OR: 1.332 [1.296, 1.369]
β: 0.287 (0.014)
AUROC: 0.575 [0.567, 0.582] Nagelkerke's Pseudo-R²: 0.0147
Brier score: 0.082
Odds Ratio (OR, top 1% vs. Rest): 2.19 [1.79, 2.67]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE172.22_GWAS-Catalog-r2019-05-03-X172.22_PT_UKB_20200608
PPM001150 PGS000465 (PRSWEB_PHECODE172.22_cSCC-Chahal_P_5e-08_MGI_20200608) PSS000545 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Squamous cell carcinoma OR: 1.457 [1.365, 1.554]
β: 0.376 (0.033)
AUROC: 0.589 [0.57, 0.61] Nagelkerke's Pseudo-R²: 0.0282
Brier score: 0.0976
Odds Ratio (OR, top 1% vs. Rest): 4.54 [3.07, 6.71]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE172.22_cSCC-Chahal_P_5e-08_MGI_20200608
PPM001152 PGS000467 (PRSWEB_PHECODE172.22_cSCC-Chahal_PT_MGI_20200608) PSS000545 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Squamous cell carcinoma OR: 1.43 [1.341, 1.525]
β: 0.358 (0.0328)
AUROC: 0.583 [0.564, 0.603] Nagelkerke's Pseudo-R²: 0.0261
Brier score: 0.0978
Odds Ratio (OR, top 1% vs. Rest): 3.75 [2.49, 5.64]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE172.22_cSCC-Chahal_PT_MGI_20200608
PPM001153 PGS000468 (PRSWEB_PHECODE172.22_cSCC-Chahal_PT_UKB_20200608) PSS000569 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Squamous cell carcinoma OR: 1.334 [1.299, 1.371]
β: 0.288 (0.0138)
AUROC: 0.571 [0.563, 0.579] Nagelkerke's Pseudo-R²: 0.0151
Brier score: 0.0819
Odds Ratio (OR, top 1% vs. Rest): 1.93 [1.56, 2.39]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE172.22_cSCC-Chahal_PT_UKB_20200608
PPM001155 PGS000470 (PRSWEB_PHECODE172.3_UKBB-SAIGE-HRC-X172.3_PT_MGI_20200608) PSS000547 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Carcinoma in situ of skin OR: 1.308 [1.208, 1.417]
β: 0.269 (0.0407)
AUROC: 0.557 [0.531, 0.582] Nagelkerke's Pseudo-R²: 0.0154
Brier score: 0.093
Odds Ratio (OR, top 1% vs. Rest): 2.45 [1.34, 4.45]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE172.3_UKBB-SAIGE-HRC-X172.3_PT_MGI_20200608
PPM001156 PGS000471 (PRSWEB_PHECODE172.3_UKBB-SAIGE-HRC-X172.3_LASSOSUM_MGI_20200608) PSS000547 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Carcinoma in situ of skin OR: 1.401 [1.297, 1.513]
β: 0.337 (0.0393)
AUROC: 0.569 [0.541, 0.595] Nagelkerke's Pseudo-R²: 0.0255
Brier score: 0.0923
Odds Ratio (OR, top 1% vs. Rest): 3.77 [2.24, 6.34]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE172.3_UKBB-SAIGE-HRC-X172.3_LASSOSUM_MGI_20200608
PPM001158 PGS000473 (PRSWEB_PHECODE174.1_20001-1002_PRS-CS_MGI_20200608) PSS000549 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Breast cancer [female] OR: 1.315 [1.238, 1.398]
β: 0.274 (0.0311)
AUROC: 0.576 [0.56, 0.592] Nagelkerke's Pseudo-R²: 0.0167
Brier score: 0.138
Odds Ratio (OR, top 1% vs. Rest): 1.6 [0.981, 2.62]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE174.1_20001-1002_PRS-CS_MGI_20200608
PPM001159 PGS000474 (PRSWEB_PHECODE174.1_20001-1002_PT_MGI_20200608) PSS000549 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Breast cancer [female] OR: 1.338 [1.26, 1.422]
β: 0.291 (0.0308)
AUROC: 0.58 [0.563, 0.597] Nagelkerke's Pseudo-R²: 0.0188
Brier score: 0.138
Odds Ratio (OR, top 1% vs. Rest): 1.54 [0.924, 2.56]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE174.1_20001-1002_PT_MGI_20200608
PPM001161 PGS000476 (PRSWEB_PHECODE174.1_C3-BREAST-3_P_5e-08_MGI_20200608) PSS000549 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Breast cancer [female] OR: 1.365 [1.286, 1.45]
β: 0.311 (0.0305)
AUROC: 0.585 [0.569, 0.603] Nagelkerke's Pseudo-R²: 0.0218
Brier score: 0.138
Odds Ratio (OR, top 1% vs. Rest): 1.97 [1.24, 3.14]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE174.1_C3-BREAST-3_P_5e-08_MGI_20200608
PPM001162 PGS000477 (PRSWEB_PHECODE174.1_C3-BREAST-3_PRS-CS_MGI_20200608) PSS000549 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Breast cancer [female] OR: 1.338 [1.259, 1.421]
β: 0.291 (0.0308)
AUROC: 0.581 [0.564, 0.597] Nagelkerke's Pseudo-R²: 0.0193
Brier score: 0.138
Odds Ratio (OR, top 1% vs. Rest): 2.17 [1.38, 3.41]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE174.1_C3-BREAST-3_PRS-CS_MGI_20200608
PPM001164 PGS000479 (PRSWEB_PHECODE174.1_C3-BREAST-3_LASSOSUM_MGI_20200608) PSS000549 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Breast cancer [female] OR: 1.438 [1.354, 1.528]
β: 0.364 (0.0308)
AUROC: 0.6 [0.584, 0.616] Nagelkerke's Pseudo-R²: 0.03
Brier score: 0.137
Odds Ratio (OR, top 1% vs. Rest): 2.37 [1.54, 3.65]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE174.1_C3-BREAST-3_LASSOSUM_MGI_20200608
PPM001167 PGS000482 (PRSWEB_PHECODE174.1_C50_PT_MGI_20200608) PSS000549 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Breast cancer [female] OR: 1.358 [1.279, 1.442]
β: 0.306 (0.0306)
AUROC: 0.584 [0.568, 0.601] Nagelkerke's Pseudo-R²: 0.0212
Brier score: 0.138
Odds Ratio (OR, top 1% vs. Rest): 1.43 [0.853, 2.41]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE174.1_C50_PT_MGI_20200608
PPM001168 PGS000483 (PRSWEB_PHECODE174.1_C50_LASSOSUM_MGI_20200608) PSS000549 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Breast cancer [female] OR: 1.404 [1.322, 1.491]
β: 0.339 (0.0308)
AUROC: 0.595 [0.579, 0.61] Nagelkerke's Pseudo-R²: 0.0264
Brier score: 0.137
Odds Ratio (OR, top 1% vs. Rest): 2.05 [1.3, 3.24]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE174.1_C50_LASSOSUM_MGI_20200608
PPM001170 PGS000485 (PRSWEB_PHECODE174.1_GWAS-Catalog-r2019-05-03-X174.1_P_5e-08_MGI_20200608) PSS000549 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Breast cancer [female] OR: 1.488 [1.399, 1.582]
β: 0.397 (0.0313)
AUROC: 0.607 [0.589, 0.623] Nagelkerke's Pseudo-R²: 0.0346
Brier score: 0.136
Odds Ratio (OR, top 1% vs. Rest): 3.06 [2.04, 4.6]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE174.1_GWAS-Catalog-r2019-05-03-X174.1_P_5e-08_MGI_20200608
PPM001171 PGS000486 (PRSWEB_PHECODE174.1_GWAS-Catalog-r2019-05-03-X174.1_P_5e-08_UKB_20200608) PSS000570 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Breast cancer [female] OR: 1.4 [1.363, 1.437]
β: 0.336 (0.0134)
AUROC: 0.592 [0.585, 0.6] Nagelkerke's Pseudo-R²: 0.0202
Brier score: 0.082
Odds Ratio (OR, top 1% vs. Rest): 2.58 [2.16, 3.07]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE174.1_GWAS-Catalog-r2019-05-03-X174.1_P_5e-08_UKB_20200608
PPM001173 PGS000488 (PRSWEB_PHECODE174.1_GWAS-Catalog-r2019-05-03-X174.1_PT_UKB_20200608) PSS000570 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Breast cancer [female] OR: 1.426 [1.389, 1.464]
β: 0.355 (0.0134)
AUROC: 0.598 [0.59, 0.605] Nagelkerke's Pseudo-R²: 0.0226
Brier score: 0.0819
Odds Ratio (OR, top 1% vs. Rest): 2.68 [2.25, 3.18]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE174.1_GWAS-Catalog-r2019-05-03-X174.1_PT_UKB_20200608
PPM001174 PGS000489 (PRSWEB_PHECODE174.1_Onco-iCOGS-ER-negative-BRCA_P_5e-08_MGI_20200608) PSS000549 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Breast cancer [female] OR: 1.254 [1.181, 1.33]
β: 0.226 (0.0304)
AUROC: 0.564 [0.547, 0.58] Nagelkerke's Pseudo-R²: 0.012
Brier score: 0.139
Odds Ratio (OR, top 1% vs. Rest): 1.72 [1.05, 2.81]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE174.1_Onco-iCOGS-ER-negative-BRCA_P_5e-08_MGI_20200608
PPM001176 PGS000491 (PRSWEB_PHECODE174.1_Onco-iCOGS-ER-negative-BRCA_PRS-CS_MGI_20200608) PSS000549 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Breast cancer [female] OR: 1.326 [1.246, 1.411]
β: 0.282 (0.0317)
AUROC: 0.578 [0.56, 0.594] Nagelkerke's Pseudo-R²: 0.0179
Brier score: 0.138
Odds Ratio (OR, top 1% vs. Rest): 1.8 [1.13, 2.88]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE174.1_Onco-iCOGS-ER-negative-BRCA_PRS-CS_MGI_20200608
PPM001177 PGS000492 (PRSWEB_PHECODE174.1_Onco-iCOGS-ER-negative-BRCA_PRS-CS_UKB_20200608) PSS000570 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Breast cancer [female] OR: 1.33 [1.296, 1.366]
β: 0.286 (0.0134)
AUROC: 0.579 [0.572, 0.586] Nagelkerke's Pseudo-R²: 0.0146
Brier score: 0.0822
Odds Ratio (OR, top 1% vs. Rest): 2.34 [1.95, 2.82]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE174.1_Onco-iCOGS-ER-negative-BRCA_PRS-CS_UKB_20200608
PPM001179 PGS000494 (PRSWEB_PHECODE174.1_Onco-iCOGS-ER-negative-BRCA_PT_UKB_20200608) PSS000570 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Breast cancer [female] OR: 1.248 [1.216, 1.28]
β: 0.221 (0.0132)
AUROC: 0.559 [0.551, 0.566] Nagelkerke's Pseudo-R²: 0.00891
Brier score: 0.0824
Odds Ratio (OR, top 1% vs. Rest): 2.03 [1.67, 2.46]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE174.1_Onco-iCOGS-ER-negative-BRCA_PT_UKB_20200608
PPM001180 PGS000495 (PRSWEB_PHECODE174.1_Onco-iCOGS-ER-negative-BRCA_LASSOSUM_MGI_20200608) PSS000549 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Breast cancer [female] OR: 1.297 [1.221, 1.377]
β: 0.26 (0.0307)
AUROC: 0.571 [0.555, 0.588] Nagelkerke's Pseudo-R²: 0.0152
Brier score: 0.138
Odds Ratio (OR, top 1% vs. Rest): 1.87 [1.16, 3.01]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE174.1_Onco-iCOGS-ER-negative-BRCA_LASSOSUM_MGI_20200608
PPM001182 PGS000497 (PRSWEB_PHECODE174.1_Onco-iCOGS-ER-positive-BRCA_P_5e-08_MGI_20200608) PSS000549 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Breast cancer [female] OR: 1.521 [1.43, 1.619]
β: 0.42 (0.0316)
AUROC: 0.614 [0.599, 0.63] Nagelkerke's Pseudo-R²: 0.0383
Brier score: 0.136
Odds Ratio (OR, top 1% vs. Rest): 2.35 [1.51, 3.66]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE174.1_Onco-iCOGS-ER-positive-BRCA_P_5e-08_MGI_20200608
PPM001183 PGS000498 (PRSWEB_PHECODE174.1_Onco-iCOGS-ER-positive-BRCA_P_5e-08_UKB_20200608) PSS000570 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Breast cancer [female] OR: 1.513 [1.474, 1.553]
β: 0.414 (0.0133)
AUROC: 0.613 [0.606, 0.621] Nagelkerke's Pseudo-R²: 0.0311
Brier score: 0.0815
Odds Ratio (OR, top 1% vs. Rest): 2.71 [2.28, 3.23]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE174.1_Onco-iCOGS-ER-positive-BRCA_P_5e-08_UKB_20200608
PPM001184 PGS000499 (PRSWEB_PHECODE174.1_Onco-iCOGS-ER-positive-BRCA_PRS-CS_MGI_20200608) PSS000549 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Breast cancer [female] OR: 1.708 [1.601, 1.822]
β: 0.535 (0.033)
AUROC: 0.643 [0.627, 0.658] Nagelkerke's Pseudo-R²: 0.0603
Brier score: 0.134
Odds Ratio (OR, top 1% vs. Rest): 3.71 [2.52, 5.47]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE174.1_Onco-iCOGS-ER-positive-BRCA_PRS-CS_MGI_20200608
PPM001186 PGS000501 (PRSWEB_PHECODE174.1_Onco-iCOGS-ER-positive-BRCA_PT_MGI_20200608) PSS000549 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Breast cancer [female] OR: 1.564 [1.469, 1.665]
β: 0.447 (0.0318)
AUROC: 0.621 [0.605, 0.638] Nagelkerke's Pseudo-R²: 0.0438
Brier score: 0.136
Odds Ratio (OR, top 1% vs. Rest): 2.7 [1.77, 4.1]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE174.1_Onco-iCOGS-ER-positive-BRCA_PT_MGI_20200608
PPM001187 PGS000502 (PRSWEB_PHECODE174.1_Onco-iCOGS-ER-positive-BRCA_PT_UKB_20200608) PSS000570 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Breast cancer [female] OR: 1.555 [1.514, 1.596]
β: 0.441 (0.0135)
AUROC: 0.621 [0.614, 0.628] Nagelkerke's Pseudo-R²: 0.0347
Brier score: 0.0814
Odds Ratio (OR, top 1% vs. Rest): 3.36 [2.87, 3.95]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE174.1_Onco-iCOGS-ER-positive-BRCA_PT_UKB_20200608
PPM001189 PGS000504 (PRSWEB_PHECODE174.1_Onco-iCOGS-ER-positive-BRCA_LASSOSUM_UKB_20200608) PSS000570 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Breast cancer [female] OR: 1.621 [1.578, 1.665]
β: 0.483 (0.0136)
AUROC: 0.631 [0.624, 0.638] Nagelkerke's Pseudo-R²: 0.0408
Brier score: 0.0811
Odds Ratio (OR, top 1% vs. Rest): 3.86 [3.31, 4.5]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE174.1_Onco-iCOGS-ER-positive-BRCA_LASSOSUM_UKB_20200608
PPM001190 PGS000505 (PRSWEB_PHECODE174.1_Onco-iCOGS-Overall-BRCA_P_5e-08_MGI_20200608) PSS000549 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Breast cancer [female] OR: 1.584 [1.488, 1.686]
β: 0.46 (0.0318)
AUROC: 0.625 [0.609, 0.641] Nagelkerke's Pseudo-R²: 0.0462
Brier score: 0.136
Odds Ratio (OR, top 1% vs. Rest): 3.32 [2.24, 4.93]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE174.1_Onco-iCOGS-Overall-BRCA_P_5e-08_MGI_20200608
PPM001215 PGS000530 (PRSWEB_PHECODE174.1_iCOGS-ER-positive-BRCA_PT_UKB_20200608) PSS000570 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Breast cancer [female] OR: 1.441 [1.404, 1.479]
β: 0.365 (0.0132)
AUROC: 0.6 [0.593, 0.608] Nagelkerke's Pseudo-R²: 0.0245
Brier score: 0.0818
Odds Ratio (OR, top 1% vs. Rest): 2.92 [2.47, 3.46]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE174.1_iCOGS-ER-positive-BRCA_PT_UKB_20200608
PPM001217 PGS000532 (PRSWEB_PHECODE174.1_iCOGS-ER-positive-BRCA_LASSOSUM_UKB_20200608) PSS000570 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Breast cancer [female] OR: 1.49 [1.451, 1.529]
β: 0.399 (0.0134)
AUROC: 0.608 [0.601, 0.615] Nagelkerke's Pseudo-R²: 0.0285
Brier score: 0.0816
Odds Ratio (OR, top 1% vs. Rest): 3.0 [2.54, 3.54]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE174.1_iCOGS-ER-positive-BRCA_LASSOSUM_UKB_20200608
PPM001218 PGS000533 (PRSWEB_PHECODE174.1_iCOGS-Overall-BRCA_P_5e-08_MGI_20200608) PSS000549 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Breast cancer [female] OR: 1.489 [1.401, 1.583]
β: 0.398 (0.0312)
AUROC: 0.607 [0.591, 0.623] Nagelkerke's Pseudo-R²: 0.0354
Brier score: 0.137
Odds Ratio (OR, top 1% vs. Rest): 2.51 [1.63, 3.86]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE174.1_iCOGS-Overall-BRCA_P_5e-08_MGI_20200608
PPM001220 PGS000535 (PRSWEB_PHECODE174.1_iCOGS-Overall-BRCA_PRS-CS_MGI_20200608) PSS000549 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Breast cancer [female] OR: 1.568 [1.473, 1.668]
β: 0.45 (0.0317)
AUROC: 0.622 [0.605, 0.638] Nagelkerke's Pseudo-R²: 0.0443
Brier score: 0.135
Odds Ratio (OR, top 1% vs. Rest): 3.43 [2.32, 5.05]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE174.1_iCOGS-Overall-BRCA_PRS-CS_MGI_20200608
PPM001221 PGS000536 (PRSWEB_PHECODE174.1_iCOGS-Overall-BRCA_PRS-CS_UKB_20200608) PSS000570 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Breast cancer [female] OR: 1.571 [1.53, 1.614]
β: 0.452 (0.0136)
AUROC: 0.623 [0.615, 0.63] Nagelkerke's Pseudo-R²: 0.036
Brier score: 0.0813
Odds Ratio (OR, top 1% vs. Rest): 3.54 [3.02, 4.14]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE174.1_iCOGS-Overall-BRCA_PRS-CS_UKB_20200608
PPM001224 PGS000539 (PRSWEB_PHECODE174.1_iCOGS-Overall-BRCA_LASSOSUM_MGI_20200608) PSS000549 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Breast cancer [female] OR: 1.585 [1.489, 1.687]
β: 0.46 (0.0319)
AUROC: 0.624 [0.607, 0.641] Nagelkerke's Pseudo-R²: 0.0464
Brier score: 0.136
Odds Ratio (OR, top 1% vs. Rest): 2.49 [1.61, 3.84]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE174.1_iCOGS-Overall-BRCA_LASSOSUM_MGI_20200608
PPM001226 PGS000541 (PRSWEB_PHECODE182_GWAS-Catalog-r2019-05-03-X182_P_5e-08_UKB_20200608) PSS000571 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Malignant neoplasm of uterus OR: 1.311 [1.209, 1.422]
β: 0.271 (0.0415)
AUROC: 0.576 [0.553, 0.6] Nagelkerke's Pseudo-R²: 0.0133
Brier score: 0.082
Odds Ratio (OR, top 1% vs. Rest): 2.12 [1.17, 3.84]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE182_GWAS-Catalog-r2019-05-03-X182_P_5e-08_UKB_20200608
PPM001227 PGS000542 (PRSWEB_PHECODE182_GWAS-Catalog-r2019-05-03-X182_PT_UKB_20200608) PSS000571 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Malignant neoplasm of uterus OR: 1.302 [1.2, 1.413]
β: 0.264 (0.0416)
AUROC: 0.572 [0.549, 0.596] Nagelkerke's Pseudo-R²: 0.0126
Brier score: 0.082
Odds Ratio (OR, top 1% vs. Rest): 2.6 [1.5, 4.51]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE182_GWAS-Catalog-r2019-05-03-X182_PT_UKB_20200608
PPM001229 PGS000544 (PRSWEB_PHECODE184.11_GWAS-Catalog-r2019-05-03-X184.11_P_5e-08_UKB_20200608) PSS000572 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Malignant neoplasm of ovary OR: 1.12 [1.021, 1.23]
β: 0.114 (0.0475)
AUROC: 0.532 [0.506, 0.559] Nagelkerke's Pseudo-R²: 0.00239
Brier score: 0.0827
Odds Ratio (OR, top 1% vs. Rest): 0.923 [0.347, 2.45]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE184.11_GWAS-Catalog-r2019-05-03-X184.11_P_5e-08_UKB_20200608
PPM001230 PGS000545 (PRSWEB_PHECODE184.11_GWAS-Catalog-r2019-05-03-X184.11_PT_UKB_20200608) PSS000572 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Malignant neoplasm of ovary OR: 1.12 [1.021, 1.23]
β: 0.114 (0.0475)
AUROC: 0.532 [0.506, 0.559] Nagelkerke's Pseudo-R²: 0.00239
Brier score: 0.0827
Odds Ratio (OR, top 1% vs. Rest): 0.923 [0.347, 2.45]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE184.11_GWAS-Catalog-r2019-05-03-X184.11_PT_UKB_20200608
PPM001232 PGS000547 (PRSWEB_PHECODE184.11_Phelan-EPOC_P_5e-08_UKB_20200608) PSS000572 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Malignant neoplasm of ovary OR: 1.156 [1.051, 1.27]
β: 0.145 (0.0482)
AUROC: 0.544 [0.517, 0.573] Nagelkerke's Pseudo-R²: 0.00379
Brier score: 0.0826
Odds Ratio (OR, top 1% vs. Rest): 0.922 [0.347, 2.45]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE184.11_Phelan-EPOC_P_5e-08_UKB_20200608
PPM001233 PGS000548 (PRSWEB_PHECODE184.11_Phelan-EPOC_LASSOSUM_UKB_20200608) PSS000572 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Malignant neoplasm of ovary OR: 1.132 [1.03, 1.244]
β: 0.124 (0.0483)
AUROC: 0.538 [0.512, 0.565] Nagelkerke's Pseudo-R²: 0.00277
Brier score: 0.0826
Odds Ratio (OR, top 1% vs. Rest): 1.13 [0.463, 2.77]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE184.11_Phelan-EPOC_LASSOSUM_UKB_20200608
PPM001235 PGS000550 (PRSWEB_PHECODE184.11_Phelan-IEOC_PRS-CS_UKB_20200608) PSS000572 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Malignant neoplasm of ovary OR: 1.286 [1.169, 1.414]
β: 0.251 (0.0485)
AUROC: 0.568 [0.542, 0.595] Nagelkerke's Pseudo-R²: 0.0113
Brier score: 0.0823
Odds Ratio (OR, top 1% vs. Rest): 1.76 [0.838, 3.7]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE184.11_Phelan-IEOC_PRS-CS_UKB_20200608
PPM001236 PGS000551 (PRSWEB_PHECODE184.11_Phelan-IEOC_PT_UKB_20200608) PSS000572 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Malignant neoplasm of ovary OR: 1.234 [1.125, 1.354]
β: 0.21 (0.0473)
AUROC: 0.558 [0.53, 0.586] Nagelkerke's Pseudo-R²: 0.00819
Brier score: 0.0824
Odds Ratio (OR, top 1% vs. Rest): 1.55 [0.71, 3.38]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE184.11_Phelan-IEOC_PT_UKB_20200608
PPM001238 PGS000553 (PRSWEB_PHECODE184.11_Phelan-LSASBOC_P_5e-08_UKB_20200608) PSS000572 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Malignant neoplasm of ovary OR: 1.188 [1.079, 1.308]
β: 0.172 (0.0491)
AUROC: 0.556 [0.53, 0.584] Nagelkerke's Pseudo-R²: 0.00531
Brier score: 0.0825
Odds Ratio (OR, top 1% vs. Rest): 1.76 [0.839, 3.69]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE184.11_Phelan-LSASBOC_P_5e-08_UKB_20200608
PPM001239 PGS000554 (PRSWEB_PHECODE184.11_Phelan-LSASBOC_PRS-CS_UKB_20200608) PSS000572 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Malignant neoplasm of ovary OR: 1.11 [1.009, 1.221]
β: 0.104 (0.0486)
AUROC: 0.522 [0.491, 0.548] Nagelkerke's Pseudo-R²: 0.00193
Brier score: 0.0827
Odds Ratio (OR, top 1% vs. Rest): 3.92 [2.27, 6.79]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE184.11_Phelan-LSASBOC_PRS-CS_UKB_20200608
PPM001241 PGS000556 (PRSWEB_PHECODE184.11_Phelan-LSASBOC_LASSOSUM_UKB_20200608) PSS000572 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Malignant neoplasm of ovary OR: 1.122 [1.022, 1.233]
β: 0.116 (0.0478)
AUROC: 0.516 [0.489, 0.544] Nagelkerke's Pseudo-R²: 0.00242
Brier score: 0.0826
Odds Ratio (OR, top 1% vs. Rest): 2.4 [1.24, 4.62]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE184.11_Phelan-LSASBOC_LASSOSUM_UKB_20200608
PPM001242 PGS000557 (PRSWEB_PHECODE184.11_Phelan-OCCC_PRS-CS_UKB_20200608) PSS000572 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Malignant neoplasm of ovary OR: 1.149 [1.045, 1.262]
β: 0.139 (0.048)
AUROC: 0.534 [0.508, 0.562] Nagelkerke's Pseudo-R²: 0.00348
Brier score: 0.0826
Odds Ratio (OR, top 1% vs. Rest): 1.55 [0.71, 3.38]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE184.11_Phelan-OCCC_PRS-CS_UKB_20200608
PPM001244 PGS000559 (PRSWEB_PHECODE184.11_Phelan-SIOC_P_5e-08_MGI_20200608) PSS000550 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Malignant neoplasm of ovary OR: 1.183 [1.015, 1.378]
β: 0.168 (0.078)
AUROC: 0.554 [0.509, 0.597] Nagelkerke's Pseudo-R²: 0.00516
Brier score: 0.0827
Odds Ratio (OR, top 1% vs. Rest): 0.784 [0.142, 4.32]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE184.11_Phelan-SIOC_P_5e-08_MGI_20200608
PPM001245 PGS000560 (PRSWEB_PHECODE184.11_Phelan-SIOC_P_5e-08_UKB_20200608) PSS000572 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Malignant neoplasm of ovary OR: 1.233 [1.125, 1.352]
β: 0.21 (0.047)
AUROC: 0.552 [0.523, 0.581] Nagelkerke's Pseudo-R²: 0.00819
Brier score: 0.0824
Odds Ratio (OR, top 1% vs. Rest): 1.76 [0.839, 3.69]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE184.11_Phelan-SIOC_P_5e-08_UKB_20200608
PPM001247 PGS000562 (PRSWEB_PHECODE184.11_Phelan-SIOC_PRS-CS_UKB_20200608) PSS000572 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Malignant neoplasm of ovary OR: 1.209 [1.099, 1.329]
β: 0.19 (0.0484)
AUROC: 0.552 [0.526, 0.58] Nagelkerke's Pseudo-R²: 0.00646
Brier score: 0.0825
Odds Ratio (OR, top 1% vs. Rest): 1.55 [0.708, 3.38]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE184.11_Phelan-SIOC_PRS-CS_UKB_20200608
PPM001248 PGS000563 (PRSWEB_PHECODE184.11_Phelan-SIOC_PT_UKB_20200608) PSS000572 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Malignant neoplasm of ovary OR: 1.192 [1.086, 1.308]
β: 0.175 (0.0476)
AUROC: 0.547 [0.52, 0.574] Brier score: 0.0826
Nagelkerke's Pseudo-R²: 0.00564
Odds Ratio (OR, top 1% vs. Rest): 0.511 [0.142, 1.84]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE184.11_Phelan-SIOC_PT_UKB_20200608
PPM001250 PGS000565 (PRSWEB_PHECODE185_20001-1044_P_5e-08_MGI_20200608) PSS000552 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Cancer of prostate OR: 1.434 [1.336, 1.54]
β: 0.361 (0.0363)
AUROC: 0.596 [0.579, 0.615] Nagelkerke's Pseudo-R²: 0.0271
Brier score: 0.151
Odds Ratio (OR, top 1% vs. Rest): 2.39 [1.41, 4.03]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE185_20001-1044_P_5e-08_MGI_20200608
PPM001251 PGS000566 (PRSWEB_PHECODE185_20001-1044_PRS-CS_MGI_20200608) PSS000552 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Cancer of prostate OR: 1.393 [1.3, 1.493]
β: 0.332 (0.0352)
AUROC: 0.591 [0.573, 0.609] Nagelkerke's Pseudo-R²: 0.0245
Brier score: 0.152
Odds Ratio (OR, top 1% vs. Rest): 2.85 [1.76, 4.62]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE185_20001-1044_PRS-CS_MGI_20200608
PPM001252 PGS000567 (PRSWEB_PHECODE185_20001-1044_PT_MGI_20200608) PSS000552 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Cancer of prostate OR: 1.505 [1.404, 1.613]
β: 0.409 (0.0354)
AUROC: 0.608 [0.59, 0.628] Nagelkerke's Pseudo-R²: 0.0379
Brier score: 0.15
Odds Ratio (OR, top 1% vs. Rest): 3.17 [1.98, 5.06]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE185_20001-1044_PT_MGI_20200608
PPM001253 PGS000568 (PRSWEB_PHECODE185_20001-1044_LASSOSUM_MGI_20200608) PSS000552 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Cancer of prostate OR: 1.426 [1.332, 1.527]
β: 0.355 (0.035)
AUROC: 0.595 [0.577, 0.614] Nagelkerke's Pseudo-R²: 0.0281
Brier score: 0.151
Odds Ratio (OR, top 1% vs. Rest): 1.53 [0.88, 2.66]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE185_20001-1044_LASSOSUM_MGI_20200608
PPM001254 PGS000569 (PRSWEB_PHECODE185_C3-PROSTATE_P_5e-08_MGI_20200608) PSS000552 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Cancer of prostate OR: 1.643 [1.531, 1.763]
β: 0.496 (0.036)
AUROC: 0.63 [0.613, 0.648] Nagelkerke's Pseudo-R²: 0.0543
Brier score: 0.148
Odds Ratio (OR, top 1% vs. Rest): 2.86 [1.79, 4.57]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE185_C3-PROSTATE_P_5e-08_MGI_20200608
PPM001256 PGS000571 (PRSWEB_PHECODE185_C3-PROSTATE_PT_MGI_20200608) PSS000552 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Cancer of prostate OR: 1.67 [1.555, 1.793]
β: 0.513 (0.0363)
AUROC: 0.634 [0.617, 0.653] Nagelkerke's Pseudo-R²: 0.0583
Brier score: 0.148
Odds Ratio (OR, top 1% vs. Rest): 2.96 [1.85, 4.74]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE185_C3-PROSTATE_PT_MGI_20200608
PPM001263 PGS000578 (PRSWEB_PHECODE185_GWAS-Catalog-r2019-05-03-X185_P_5e-08_UKB_20200608) PSS000573 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Cancer of prostate OR: 1.746 [1.681, 1.813]
β: 0.557 (0.0192)
AUROC: 0.653 [0.642, 0.662] Nagelkerke's Pseudo-R²: 0.0565
Brier score: 0.0813
Odds Ratio (OR, top 1% vs. Rest): 4.31 [3.48, 5.33]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE185_GWAS-Catalog-r2019-05-03-X185_P_5e-08_UKB_20200608
PPM001265 PGS000580 (PRSWEB_PHECODE185_GWAS-Catalog-r2019-05-03-X185_PT_UKB_20200608) PSS000573 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Cancer of prostate OR: 1.748 [1.684, 1.815]
β: 0.559 (0.0192)
AUROC: 0.653 [0.643, 0.663] Nagelkerke's Pseudo-R²: 0.0568
Brier score: 0.0813
Odds Ratio (OR, top 1% vs. Rest): 4.34 [3.51, 5.37]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE185_GWAS-Catalog-r2019-05-03-X185_PT_UKB_20200608
PPM001266 PGS000581 (PRSWEB_PHECODE185_Pca-PRACTICAL_P_5e-08_MGI_20200608) PSS000552 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Cancer of prostate OR: 1.79 [1.665, 1.925]
β: 0.582 (0.0371)
AUROC: 0.651 [0.634, 0.669] Nagelkerke's Pseudo-R²: 0.071
Brier score: 0.146
Odds Ratio (OR, top 1% vs. Rest): 4.44 [2.87, 6.87]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE185_Pca-PRACTICAL_P_5e-08_MGI_20200608
PPM001268 PGS000583 (PRSWEB_PHECODE185_Pca-PRACTICAL_PRS-CS_MGI_20200608) PSS000552 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Cancer of prostate OR: 1.929 [1.79, 2.078]
β: 0.657 (0.038)
AUROC: 0.668 [0.651, 0.687] Nagelkerke's Pseudo-R²: 0.0874
Brier score: 0.145
Odds Ratio (OR, top 1% vs. Rest): 3.61 [2.28, 5.72]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE185_Pca-PRACTICAL_PRS-CS_MGI_20200608
PPM001269 PGS000584 (PRSWEB_PHECODE185_Pca-PRACTICAL_PRS-CS_UKB_20200608) PSS000573 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Cancer of prostate OR: 2.173 [2.087, 2.263]
β: 0.776 (0.0206)
AUROC: 0.705 [0.695, 0.715] Nagelkerke's Pseudo-R²: 0.1
Brier score: 0.0791
Odds Ratio (OR, top 1% vs. Rest): 5.58 [4.58, 6.78]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE185_Pca-PRACTICAL_PRS-CS_UKB_20200608
PPM001271 PGS000586 (PRSWEB_PHECODE185_Pca-PRACTICAL_PT_UKB_20200608) PSS000573 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Cancer of prostate OR: 2.018 [1.94, 2.1]
β: 0.702 (0.0203)
AUROC: 0.687 [0.678, 0.698] Nagelkerke's Pseudo-R²: 0.0837
Brier score: 0.0799
Odds Ratio (OR, top 1% vs. Rest): 5.88 [4.84, 7.13]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE185_Pca-PRACTICAL_PT_UKB_20200608
PPM001272 PGS000587 (PRSWEB_PHECODE185_Pca-PRACTICAL_LASSOSUM_MGI_20200608) PSS000552 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Cancer of prostate OR: 1.906 [1.771, 2.051]
β: 0.645 (0.0375)
AUROC: 0.665 [0.647, 0.684] Nagelkerke's Pseudo-R²: 0.0861
Brier score: 0.145
Odds Ratio (OR, top 1% vs. Rest): 4.92 [3.21, 7.55]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE185_Pca-PRACTICAL_LASSOSUM_MGI_20200608
PPM001274 PGS000589 (PRSWEB_PHECODE185_UKBB-SAIGE-HRC-X185_P_5e-08_MGI_20200608) PSS000552 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Cancer of prostate OR: 1.63 [1.52, 1.748]
β: 0.489 (0.0356)
AUROC: 0.63 [0.612, 0.648] Nagelkerke's Pseudo-R²: 0.0532
Brier score: 0.148
Odds Ratio (OR, top 1% vs. Rest): 3.14 [1.99, 4.96]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE185_UKBB-SAIGE-HRC-X185_P_5e-08_MGI_20200608
PPM001275 PGS000590 (PRSWEB_PHECODE185_UKBB-SAIGE-HRC-X185_PRS-CS_MGI_20200608) PSS000552 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Cancer of prostate OR: 1.516 [1.415, 1.624]
β: 0.416 (0.0353)
AUROC: 0.614 [0.595, 0.633] Nagelkerke's Pseudo-R²: 0.0395
Brier score: 0.15
Odds Ratio (OR, top 1% vs. Rest): 2.32 [1.42, 3.78]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE185_UKBB-SAIGE-HRC-X185_PRS-CS_MGI_20200608
PPM001277 PGS000592 (PRSWEB_PHECODE185_UKBB-SAIGE-HRC-X185_LASSOSUM_MGI_20200608) PSS000552 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Cancer of prostate OR: 1.537 [1.433, 1.648]
β: 0.43 (0.0357)
AUROC: 0.616 [0.598, 0.635] Nagelkerke's Pseudo-R²: 0.0408
Brier score: 0.15
Odds Ratio (OR, top 1% vs. Rest): 2.55 [1.55, 4.2]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE185_UKBB-SAIGE-HRC-X185_LASSOSUM_MGI_20200608
PPM001278 PGS000593 (PRSWEB_PHECODE187_C3-MALE-GENITAL_P_5e-08_MGI_20200608) PSS000554 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Cancer of other male genital organs OR: 1.193 [1.002, 1.419]
β: 0.176 (0.0887)
AUROC: 0.551 [0.5, 0.6] Nagelkerke's Pseudo-R²: 0.00553
Brier score: 0.0831
Odds Ratio (OR, top 1% vs. Rest): 1.01 [0.177, 5.76]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE187_C3-MALE-GENITAL_P_5e-08_MGI_20200608
PPM001280 PGS000595 (PRSWEB_PHECODE187.2_20001-1045_P_5e-08_MGI_20200608) PSS000553 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Malignant neoplasm of testis OR: 1.713 [1.33, 2.206]
β: 0.538 (0.129)
AUROC: 0.658 [0.594, 0.719] Nagelkerke's Pseudo-R²: 0.0543
Brier score: 0.0838
Odds Ratio (OR, top 1% vs. Rest): 2.64 [0.535, 13.0]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE187.2_20001-1045_P_5e-08_MGI_20200608
PPM001281 PGS000596 (PRSWEB_PHECODE187.2_20001-1045_PT_MGI_20200608) PSS000553 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Malignant neoplasm of testis OR: 1.68 [1.28, 2.206]
β: 0.519 (0.139)
AUROC: 0.649 [0.586, 0.714] Nagelkerke's Pseudo-R²: 0.0475
Brier score: 0.0841
Odds Ratio (OR, top 1% vs. Rest): 3.49 [0.816, 14.9]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE187.2_20001-1045_PT_MGI_20200608
PPM001283 PGS000598 (PRSWEB_PHECODE187.2_C3-TESTIS_P_5e-08_MGI_20200608) PSS000553 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Malignant neoplasm of testis OR: 1.639 [1.263, 2.126]
β: 0.494 (0.133)
AUROC: 0.648 [0.581, 0.712] Nagelkerke's Pseudo-R²: 0.0447
Brier score: 0.0841
Odds Ratio (OR, top 1% vs. Rest): 3.85 [0.942, 15.7]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE187.2_C3-TESTIS_P_5e-08_MGI_20200608
PPM001284 PGS000599 (PRSWEB_PHECODE187.2_C3-TESTIS_PT_MGI_20200608) PSS000553 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Malignant neoplasm of testis OR: 1.628 [1.281, 2.069]
β: 0.487 (0.122)
AUROC: 0.637 [0.568, 0.703] Nagelkerke's Pseudo-R²: 0.0473
Brier score: 0.0844
Odds Ratio (OR, top 1% vs. Rest): 4.35 [1.08, 17.5]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE187.2_C3-TESTIS_PT_MGI_20200608
PPM001286 PGS000601 (PRSWEB_PHECODE187.2_GWAS-Catalog-r2019-05-03-X187.2_P_5e-08_MGI_20200608) PSS000553 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Malignant neoplasm of testis OR: 1.438 [1.132, 1.827]
β: 0.363 (0.122)
AUROC: 0.598 [0.526, 0.672] Nagelkerke's Pseudo-R²: 0.0258
Brier score: 0.085
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE187.2_GWAS-Catalog-r2019-05-03-X187.2_P_5e-08_MGI_20200608
PPM001287 PGS000602 (PRSWEB_PHECODE187.2_GWAS-Catalog-r2019-05-03-X187.2_P_5e-08_UKB_20200608) PSS000574 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Malignant neoplasm of testis OR: 2.055 [1.692, 2.496]
β: 0.72 (0.0993)
AUROC: 0.698 [0.656, 0.74] Nagelkerke's Pseudo-R²: 0.0839
Brier score: 0.0795
Odds Ratio (OR, top 1% vs. Rest): 4.6 [1.75, 12.1]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE187.2_GWAS-Catalog-r2019-05-03-X187.2_P_5e-08_UKB_20200608
PPM001289 PGS000604 (PRSWEB_PHECODE187.2_GWAS-Catalog-r2019-05-03-X187.2_PT_UKB_20200608) PSS000574 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Malignant neoplasm of testis OR: 2.106 [1.729, 2.565]
β: 0.745 (0.101)
AUROC: 0.703 [0.659, 0.745] Brier score: 0.0793
Nagelkerke's Pseudo-R²: 0.0882
Odds Ratio (OR, top 1% vs. Rest): 4.6 [1.75, 12.1]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE187.2_GWAS-Catalog-r2019-05-03-X187.2_PT_UKB_20200608
PPM001290 PGS000605 (PRSWEB_PHECODE189.11_GWAS-Catalog-r2019-05-03-X189.11_P_5e-08_UKB_20200608) PSS000575 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Malignant neoplasm of kidney, except pelvis OR: 1.154 [1.062, 1.254]
β: 0.143 (0.0426)
AUROC: 0.517 [0.492, 0.54] Nagelkerke's Pseudo-R²: 0.00398
Brier score: 0.0825
Odds Ratio (OR, top 1% vs. Rest): 2.17 [1.13, 4.14]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE189.11_GWAS-Catalog-r2019-05-03-X189.11_P_5e-08_UKB_20200608
PPM001291 PGS000606 (PRSWEB_PHECODE189.11_GWAS-Catalog-r2019-05-03-X189.11_PT_UKB_20200608) PSS000575 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Malignant neoplasm of kidney, except pelvis OR: 1.154 [1.062, 1.254]
β: 0.143 (0.0426)
AUROC: 0.517 [0.492, 0.54] Nagelkerke's Pseudo-R²: 0.00398
Brier score: 0.0825
Odds Ratio (OR, top 1% vs. Rest): 2.17 [1.13, 4.14]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE189.11_GWAS-Catalog-r2019-05-03-X189.11_PT_UKB_20200608
PPM001293 PGS000608 (PRSWEB_PHECODE189.2_C3-BLADDER_PRS-CS_MGI_20200608) PSS000555 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Cancer of bladder OR: 1.084 [1.006, 1.167]
β: 0.0803 (0.0377)
AUROC: 0.521 [0.499, 0.541] Nagelkerke's Pseudo-R²: 0.00124
Brier score: 0.0922
Odds Ratio (OR, top 1% vs. Rest): 1.53 [0.832, 2.83]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE189.2_C3-BLADDER_PRS-CS_MGI_20200608
PPM001295 PGS000610 (PRSWEB_PHECODE189.2_GWAS-Catalog-r2019-05-03-X189.2_P_5e-08_MGI_20200608) PSS000555 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Cancer of bladder OR: 1.292 [1.201, 1.391]
β: 0.256 (0.0375)
AUROC: 0.572 [0.55, 0.594] Nagelkerke's Pseudo-R²: 0.013
Brier score: 0.0917
Odds Ratio (OR, top 1% vs. Rest): 1.47 [0.779, 2.77]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE189.2_GWAS-Catalog-r2019-05-03-X189.2_P_5e-08_MGI_20200608
PPM001298 PGS000613 (PRSWEB_PHECODE189.2_GWAS-Catalog-r2019-05-03-X189.2_PT_UKB_20200608) PSS000576 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Cancer of bladder OR: 1.301 [1.227, 1.379]
β: 0.263 (0.0299)
AUROC: 0.571 [0.555, 0.588] Nagelkerke's Pseudo-R²: 0.0125
Brier score: 0.0821
Odds Ratio (OR, top 1% vs. Rest): 2.91 [1.99, 4.24]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE189.2_GWAS-Catalog-r2019-05-03-X189.2_PT_UKB_20200608
PPM001299 PGS000614 (PRSWEB_PHECODE189.2_UKBB-SAIGE-HRC-X189.2_PRS-CS_MGI_20200608) PSS000555 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Cancer of bladder OR: 1.087 [1.01, 1.171]
β: 0.0836 (0.0377)
AUROC: 0.525 [0.503, 0.547] Nagelkerke's Pseudo-R²: 0.00135
Brier score: 0.0922
Odds Ratio (OR, top 1% vs. Rest): 0.675 [0.28, 1.62]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE189.2_UKBB-SAIGE-HRC-X189.2_PRS-CS_MGI_20200608
PPM001301 PGS000616 (PRSWEB_PHECODE189.2_UKBB-SAIGE-HRC-X189.2_LASSOSUM_MGI_20200608) PSS000555 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Cancer of bladder OR: 1.138 [1.057, 1.225]
β: 0.129 (0.0376)
AUROC: 0.538 [0.517, 0.557] Nagelkerke's Pseudo-R²: 0.00345
Brier score: 0.0921
Odds Ratio (OR, top 1% vs. Rest): 0.983 [0.459, 2.11]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE189.2_UKBB-SAIGE-HRC-X189.2_LASSOSUM_MGI_20200608
PPM001302 PGS000617 (PRSWEB_PHECODE190_20001-1030_PRS-CS_MGI_20200608) PSS000556 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Cancer of eye OR: 1.339 [1.033, 1.736]
β: 0.292 (0.132)
AUROC: 0.586 [0.508, 0.658] Nagelkerke's Pseudo-R²: 0.0152
Brier score: 0.0831
Odds Ratio (OR, top 1% vs. Rest): 4.74 [1.2, 18.7]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE190_20001-1030_PRS-CS_MGI_20200608
PPM001303 PGS000618 (PRSWEB_PHECODE191.1_GWAS-Catalog-r2019-05-03-X191.1_P_5e-08_UKB_20200608) PSS000578 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Cancer of brain and nervous system OR: 1.569 [1.399, 1.759]
β: 0.45 (0.0585)
AUROC: 0.623 [0.592, 0.656] Nagelkerke's Pseudo-R²: 0.0401
Brier score: 0.0812
Odds Ratio (OR, top 1% vs. Rest): 3.64 [1.76, 7.53]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE191.1_GWAS-Catalog-r2019-05-03-X191.1_P_5e-08_UKB_20200608
PPM001305 PGS000620 (PRSWEB_PHECODE191.11_C71_LASSOSUM_MGI_20200608) PSS000557 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Cancer of brain OR: 1.195 [1.045, 1.367]
β: 0.179 (0.0686)
AUROC: 0.546 [0.504, 0.587] Nagelkerke's Pseudo-R²: 0.00561
Brier score: 0.0824
Odds Ratio (OR, top 1% vs. Rest): 1.42 [0.453, 4.47]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE191.11_C71_LASSOSUM_MGI_20200608
PPM001306 PGS000621 (PRSWEB_PHECODE191.11_GWAS-Catalog-r2019-05-03-X191.11_P_5e-08_MGI_20200608) PSS000557 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Cancer of brain OR: 1.159 [1.015, 1.324]
β: 0.148 (0.068)
AUROC: 0.54 [0.503, 0.579] Nagelkerke's Pseudo-R²: 0.00394
Brier score: 0.0825
Odds Ratio (OR, top 1% vs. Rest): 1.02 [0.271, 3.86]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE191.11_GWAS-Catalog-r2019-05-03-X191.11_P_5e-08_MGI_20200608
PPM001308 PGS000623 (PRSWEB_PHECODE191.11_GWAS-Catalog-r2019-05-03-X191.11_PT_MGI_20200608) PSS000557 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Cancer of brain OR: 1.153 [1.01, 1.316]
β: 0.142 (0.0676)
AUROC: 0.538 [0.501, 0.577] Nagelkerke's Pseudo-R²: 0.00369
Brier score: 0.0825
Odds Ratio (OR, top 1% vs. Rest): 0.602 [0.113, 3.22]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE191.11_GWAS-Catalog-r2019-05-03-X191.11_PT_MGI_20200608
PPM001309 PGS000624 (PRSWEB_PHECODE191.11_GWAS-Catalog-r2019-05-03-X191.11_PT_UKB_20200608) PSS000577 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Cancer of brain OR: 1.515 [1.344, 1.708]
β: 0.415 (0.0611)
AUROC: 0.606 [0.568, 0.642] Nagelkerke's Pseudo-R²: 0.0326
Brier score: 0.0813
Odds Ratio (OR, top 1% vs. Rest): 4.15 [2.04, 8.41]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE191.11_GWAS-Catalog-r2019-05-03-X191.11_PT_UKB_20200608
PPM001311 PGS000626 (PRSWEB_PHECODE193_20001-1065_PT_MGI_20200608) PSS000558 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Thyroid cancer OR: 1.161 [1.048, 1.285]
β: 0.149 (0.052)
AUROC: 0.529 [0.496, 0.559] Nagelkerke's Pseudo-R²: 0.0041
Brier score: 0.0826
Odds Ratio (OR, top 1% vs. Rest): 2.44 [1.18, 5.02]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE193_20001-1065_PT_MGI_20200608
PPM001312 PGS000627 (PRSWEB_PHECODE193_C3-THYROID-GLAND_PT_MGI_20200608) PSS000558 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Thyroid cancer OR: 1.27 [1.148, 1.405]
β: 0.239 (0.0515)
AUROC: 0.56 [0.53, 0.59] Nagelkerke's Pseudo-R²: 0.0107
Brier score: 0.0824
Odds Ratio (OR, top 1% vs. Rest): 2.42 [1.17, 4.98]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE193_C3-THYROID-GLAND_PT_MGI_20200608
PPM001313 PGS000628 (PRSWEB_PHECODE193_C3-THYROID-GLAND_LASSOSUM_MGI_20200608) PSS000558 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Thyroid cancer OR: 1.276 [1.155, 1.41]
β: 0.244 (0.0509)
AUROC: 0.565 [0.535, 0.595] Nagelkerke's Pseudo-R²: 0.0114
Brier score: 0.0823
Odds Ratio (OR, top 1% vs. Rest): 1.91 [0.861, 4.22]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE193_C3-THYROID-GLAND_LASSOSUM_MGI_20200608
PPM001315 PGS000630 (PRSWEB_PHECODE193_GWAS-Catalog-r2019-05-03-X193_P_5e-08_MGI_20200608) PSS000558 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Thyroid cancer OR: 1.598 [1.439, 1.775]
β: 0.469 (0.0536)
AUROC: 0.626 [0.597, 0.655] Nagelkerke's Pseudo-R²: 0.0393
Brier score: 0.0811
Odds Ratio (OR, top 1% vs. Rest): 3.53 [1.87, 6.66]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE193_GWAS-Catalog-r2019-05-03-X193_P_5e-08_MGI_20200608
PPM001316 PGS000631 (PRSWEB_PHECODE193_GWAS-Catalog-r2019-05-03-X193_P_5e-08_UKB_20200608) PSS000579 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Thyroid cancer OR: 1.651 [1.41, 1.934]
β: 0.501 (0.0806)
AUROC: 0.636 [0.589, 0.682] Nagelkerke's Pseudo-R²: 0.0478
Brier score: 0.0803
Odds Ratio (OR, top 1% vs. Rest): 4.4 [1.81, 10.7]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE193_GWAS-Catalog-r2019-05-03-X193_P_5e-08_UKB_20200608
PPM001318 PGS000633 (PRSWEB_PHECODE193_GWAS-Catalog-r2019-05-03-X193_PT_UKB_20200608) PSS000579 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Thyroid cancer OR: 1.609 [1.38, 1.876]
β: 0.476 (0.0783)
AUROC: 0.628 [0.582, 0.675] Nagelkerke's Pseudo-R²: 0.0447
Brier score: 0.0804
Odds Ratio (OR, top 1% vs. Rest): 4.41 [1.81, 10.7]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE193_GWAS-Catalog-r2019-05-03-X193_PT_UKB_20200608
PPM001319 PGS000634 (PRSWEB_PHECODE193_UKBB-SAIGE-HRC-X193_PRS-CS_MGI_20200608) PSS000558 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Thyroid cancer OR: 1.119 [1.008, 1.241]
β: 0.112 (0.053)
AUROC: 0.535 [0.504, 0.567] Nagelkerke's Pseudo-R²: 0.00228
Brier score: 0.0827
Odds Ratio (OR, top 1% vs. Rest): 1.39 [0.562, 3.45]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE193_UKBB-SAIGE-HRC-X193_PRS-CS_MGI_20200608
PPM001321 PGS000636 (PRSWEB_PHECODE193_UKBB-SAIGE-HRC-X193_LASSOSUM_MGI_20200608) PSS000558 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Thyroid cancer OR: 1.385 [1.254, 1.529]
β: 0.325 (0.0507)
AUROC: 0.578 [0.548, 0.607] Nagelkerke's Pseudo-R²: 0.0205
Brier score: 0.0819
Odds Ratio (OR, top 1% vs. Rest): 3.21 [1.67, 6.15]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE193_UKBB-SAIGE-HRC-X193_LASSOSUM_MGI_20200608
PPM001322 PGS000637 (PRSWEB_PHECODE201_20001-1052_PRS-CS_MGI_20200608) PSS000559 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Hodgkin's disease OR: 1.3 [1.023, 1.651]
β: 0.262 (0.122)
AUROC: 0.574 [0.501, 0.642] Nagelkerke's Pseudo-R²: 0.013
Brier score: 0.0826
Odds Ratio (OR, top 1% vs. Rest): 1.67 [0.264, 10.5]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE201_20001-1052_PRS-CS_MGI_20200608
PPM001324 PGS000639 (PRSWEB_PHECODE201_GWAS-Catalog-r2019-05-03-X201_PT_MGI_20200608) PSS000559 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Hodgkin's disease OR: 1.476 [1.154, 1.889]
β: 0.39 (0.126)
AUROC: 0.62 [0.559, 0.688] Nagelkerke's Pseudo-R²: 0.0276
Brier score: 0.0821
Odds Ratio (OR, top 1% vs. Rest): 2.64 [0.572, 12.2]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE201_GWAS-Catalog-r2019-05-03-X201_PT_MGI_20200608
PPM001325 PGS000640 (PRSWEB_PHECODE201_UKBB-SAIGE-HRC-X201_LASSOSUM_MGI_20200608) PSS000559 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Hodgkin's disease OR: 1.292 [1.011, 1.651]
β: 0.256 (0.125)
AUROC: 0.569 [0.501, 0.634] Nagelkerke's Pseudo-R²: 0.0109
Brier score: 0.0828
Odds Ratio (OR, top 1% vs. Rest): 1.64 [0.261, 10.3]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE201_UKBB-SAIGE-HRC-X201_LASSOSUM_MGI_20200608
PPM001326 PGS000641 (PRSWEB_PHECODE202.2_GWAS-Catalog-r2019-05-03-X202.2_P_5e-08_UKB_20200608) PSS000580 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Non-Hodgkins lymphoma OR: 1.211 [1.133, 1.294]
β: 0.191 (0.034)
AUROC: 0.541 [0.521, 0.561] Nagelkerke's Pseudo-R²: 0.00682
Brier score: 0.0821
Odds Ratio (OR, top 1% vs. Rest): 2.05 [1.24, 3.4]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE202.2_GWAS-Catalog-r2019-05-03-X202.2_P_5e-08_UKB_20200608
PPM001328 PGS000643 (PRSWEB_PHECODE202.21_C-FOLLICULAR-LYMPHOMA_PRS-CS_MGI_20200608) PSS000560 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Nodular lymphoma OR: 1.133 [1.005, 1.277]
β: 0.125 (0.061)
AUROC: 0.532 [0.497, 0.568] Nagelkerke's Pseudo-R²: 0.00282
Brier score: 0.0825
Odds Ratio (OR, top 1% vs. Rest): 2.49 [1.1, 5.65]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE202.21_C-FOLLICULAR-LYMPHOMA_PRS-CS_MGI_20200608
PPM001329 PGS000644 (PRSWEB_PHECODE202.21_C-FOLLICULAR-LYMPHOMA_LASSOSUM_MGI_20200608) PSS000560 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Nodular lymphoma OR: 1.149 [1.021, 1.294]
β: 0.139 (0.0606)
AUROC: 0.538 [0.504, 0.573] Nagelkerke's Pseudo-R²: 0.00349
Brier score: 0.0825
Odds Ratio (OR, top 1% vs. Rest): 1.48 [0.538, 4.05]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE202.21_C-FOLLICULAR-LYMPHOMA_LASSOSUM_MGI_20200608
PPM001331 PGS000646 (PRSWEB_PHECODE204.12_GWAS-Catalog-r2019-05-03-X204.12_P_5e-08_MGI_20200608) PSS000561 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Lymphoid leukemia, chronic OR: 2.104 [1.628, 2.718]
β: 0.744 (0.131)
AUROC: 0.696 [0.628, 0.765] Nagelkerke's Pseudo-R²: 0.0973
Brier score: 0.0779
Odds Ratio (OR, top 1% vs. Rest): 11.3 [3.76, 33.9]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE204.12_GWAS-Catalog-r2019-05-03-X204.12_P_5e-08_MGI_20200608
PPM001332 PGS000647 (PRSWEB_PHECODE204.12_GWAS-Catalog-r2019-05-03-X204.12_P_5e-08_UKB_20200608) PSS000581 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Lymphoid leukemia, chronic OR: 1.874 [1.639, 2.144]
β: 0.628 (0.0685)
AUROC: 0.675 [0.64, 0.707] Nagelkerke's Pseudo-R²: 0.0689
Brier score: 0.0795
Odds Ratio (OR, top 1% vs. Rest): 4.11 [1.97, 8.6]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE204.12_GWAS-Catalog-r2019-05-03-X204.12_P_5e-08_UKB_20200608
PPM001334 PGS000649 (PRSWEB_PHECODE204.12_GWAS-Catalog-r2019-05-03-X204.12_PT_UKB_20200608) PSS000581 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Lymphoid leukemia, chronic OR: 1.85 [1.619, 2.114]
β: 0.615 (0.0681)
AUROC: 0.672 [0.637, 0.703] Nagelkerke's Pseudo-R²: 0.0665
Brier score: 0.0796
Odds Ratio (OR, top 1% vs. Rest): 2.52 [1.04, 6.08]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE204.12_GWAS-Catalog-r2019-05-03-X204.12_PT_UKB_20200608
PPM001335 PGS000650 (PRSWEB_PHECODE204.12_UKBB-SAIGE-HRC-X204.12_PT_MGI_20200608) PSS000561 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Lymphoid leukemia, chronic OR: 1.368 [1.097, 1.705]
β: 0.313 (0.113)
AUROC: 0.577 [0.511, 0.645] Nagelkerke's Pseudo-R²: 0.0205
Brier score: 0.0822
Odds Ratio (OR, top 1% vs. Rest): 2.0 [0.308, 13.0]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE204.12_UKBB-SAIGE-HRC-X204.12_PT_MGI_20200608
PPM001337 PGS000652 (PRSWEB_PHECODE204.4_C90_PT_MGI_20200608) PSS000563 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Multiple myeloma OR: 1.24 [1.005, 1.529]
β: 0.215 (0.107)
AUROC: 0.547 [0.479, 0.613] Nagelkerke's Pseudo-R²: 0.00945
Brier score: 0.0823
Odds Ratio (OR, top 1% vs. Rest): 2.6 [0.593, 11.4]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE204.4_C90_PT_MGI_20200608
PPM001338 PGS000653 (PRSWEB_PHECODE204.4_GWAS-Catalog-r2019-05-03-X204.4_P_5e-08_UKB_20200608) PSS000582 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Multiple myeloma OR: 1.327 [1.165, 1.511]
β: 0.283 (0.0663)
AUROC: 0.577 [0.537, 0.617] Nagelkerke's Pseudo-R²: 0.0145
Brier score: 0.0818
Odds Ratio (OR, top 1% vs. Rest): 2.2 [0.855, 5.66]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE204.4_GWAS-Catalog-r2019-05-03-X204.4_P_5e-08_UKB_20200608
PPM001191 PGS000506 (PRSWEB_PHECODE174.1_Onco-iCOGS-Overall-BRCA_P_5e-08_UKB_20200608) PSS000570 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Breast cancer [female] OR: 1.567 [1.526, 1.609]
β: 0.449 (0.0134)
AUROC: 0.622 [0.615, 0.63] Nagelkerke's Pseudo-R²: 0.0361
Brier score: 0.0813
Odds Ratio (OR, top 1% vs. Rest): 3.69 [3.16, 4.31]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE174.1_Onco-iCOGS-Overall-BRCA_P_5e-08_UKB_20200608
PPM001193 PGS000508 (PRSWEB_PHECODE174.1_Onco-iCOGS-Overall-BRCA_PRS-CS_UKB_20200608) PSS000570 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Breast cancer [female] OR: 1.756 [1.709, 1.804]
β: 0.563 (0.0138)
AUROC: 0.652 [0.645, 0.658] Nagelkerke's Pseudo-R²: 0.0548
Brier score: 0.0805
Odds Ratio (OR, top 1% vs. Rest): 4.38 [3.79, 5.07]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE174.1_Onco-iCOGS-Overall-BRCA_PRS-CS_UKB_20200608
PPM001194 PGS000509 (PRSWEB_PHECODE174.1_Onco-iCOGS-Overall-BRCA_PT_MGI_20200608) PSS000549 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Breast cancer [female] OR: 1.643 [1.542, 1.75]
β: 0.496 (0.0323)
AUROC: 0.635 [0.618, 0.651] Nagelkerke's Pseudo-R²: 0.0532
Brier score: 0.135
Odds Ratio (OR, top 1% vs. Rest): 2.84 [1.88, 4.28]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE174.1_Onco-iCOGS-Overall-BRCA_PT_MGI_20200608
PPM001196 PGS000511 (PRSWEB_PHECODE174.1_Onco-iCOGS-Overall-BRCA_LASSOSUM_MGI_20200608) PSS000549 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Breast cancer [female] OR: 1.7 [1.594, 1.813]
β: 0.53 (0.0328)
AUROC: 0.641 [0.625, 0.656] Nagelkerke's Pseudo-R²: 0.0592
Brier score: 0.134
Odds Ratio (OR, top 1% vs. Rest): 2.48 [1.63, 3.77]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE174.1_Onco-iCOGS-Overall-BRCA_LASSOSUM_MGI_20200608
PPM001197 PGS000512 (PRSWEB_PHECODE174.1_Onco-iCOGS-Overall-BRCA_LASSOSUM_UKB_20200608) PSS000570 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Breast cancer [female] OR: 1.699 [1.654, 1.746]
β: 0.53 (0.0138)
AUROC: 0.643 [0.637, 0.65] Nagelkerke's Pseudo-R²: 0.0487
Brier score: 0.0807
Odds Ratio (OR, top 1% vs. Rest): 4.02 [3.46, 4.67]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE174.1_Onco-iCOGS-Overall-BRCA_LASSOSUM_UKB_20200608
PPM001199 PGS000514 (PRSWEB_PHECODE174.1_UKBB-SAIGE-HRC-X174.1_PRS-CS_MGI_20200608) PSS000549 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Breast cancer [female] OR: 1.391 [1.309, 1.478]
β: 0.33 (0.031)
AUROC: 0.59 [0.573, 0.607] Nagelkerke's Pseudo-R²: 0.0248
Brier score: 0.137
Odds Ratio (OR, top 1% vs. Rest): 1.79 [1.12, 2.86]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE174.1_UKBB-SAIGE-HRC-X174.1_PRS-CS_MGI_20200608
PPM001259 PGS000574 (PRSWEB_PHECODE185_C61_PRS-CS_MGI_20200608) PSS000552 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Cancer of prostate OR: 1.506 [1.406, 1.614]
β: 0.41 (0.0352)
AUROC: 0.612 [0.593, 0.63] Nagelkerke's Pseudo-R²: 0.039
Brier score: 0.15
Odds Ratio (OR, top 1% vs. Rest): 2.09 [1.24, 3.52]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE185_C61_PRS-CS_MGI_20200608
PPM001200 PGS000515 (PRSWEB_PHECODE174.1_UKBB-SAIGE-HRC-X174.1_PT_MGI_20200608) PSS000549 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Breast cancer [female] OR: 1.453 [1.367, 1.544]
β: 0.374 (0.0311)
AUROC: 0.605 [0.588, 0.621] Nagelkerke's Pseudo-R²: 0.0307
Brier score: 0.137
Odds Ratio (OR, top 1% vs. Rest): 2.09 [1.31, 3.32]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE174.1_UKBB-SAIGE-HRC-X174.1_PT_MGI_20200608
PPM001202 PGS000517 (PRSWEB_PHECODE174.1_iCOGS-ER-negative-BRCA_P_5e-08_MGI_20200608) PSS000549 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Breast cancer [female] OR: 1.229 [1.157, 1.305]
β: 0.206 (0.0306)
AUROC: 0.55 [0.533, 0.566] Nagelkerke's Pseudo-R²: 0.0097
Brier score: 0.139
Odds Ratio (OR, top 1% vs. Rest): 1.88 [1.17, 3.03]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE174.1_iCOGS-ER-negative-BRCA_P_5e-08_MGI_20200608
PPM001203 PGS000518 (PRSWEB_PHECODE174.1_iCOGS-ER-negative-BRCA_P_5e-08_UKB_20200608) PSS000570 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Breast cancer [female] OR: 1.18 [1.15, 1.21]
β: 0.165 (0.0131)
AUROC: 0.542 [0.534, 0.55] Nagelkerke's Pseudo-R²: 0.00504
Brier score: 0.0826
Odds Ratio (OR, top 1% vs. Rest): 1.49 [1.2, 1.86]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE174.1_iCOGS-ER-negative-BRCA_P_5e-08_UKB_20200608
PPM001051 PGS000366 (PRSWEB_PHECODE150_UKBB-SAIGE-HRC-X150_PRS-CS_MGI_20200608) PSS000537 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Cancer of esophagus OR: 1.24 [1.067, 1.441]
β: 0.215 (0.0766)
AUROC: 0.564 [0.522, 0.605] Nagelkerke's Pseudo-R²: 0.00839
Brier score: 0.0825
Odds Ratio (OR, top 1% vs. Rest): 1.28 [0.332, 4.95]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE150_UKBB-SAIGE-HRC-X150_PRS-CS_MGI_20200608
PPM001115 PGS000430 (PRSWEB_PHECODE172.1_UKBB-SAIGE-HRC-X172.1_PRS-CS_MGI_20200608) PSS000543 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Melanomas of skin, dx or hx OR: 1.219 [1.151, 1.292]
β: 0.198 (0.0296)
AUROC: 0.555 [0.54, 0.573] Nagelkerke's Pseudo-R²: 0.00721
Brier score: 0.0965
Odds Ratio (OR, top 1% vs. Rest): 1.64 [1.01, 2.66]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE172.1_UKBB-SAIGE-HRC-X172.1_PRS-CS_MGI_20200608
PPM001185 PGS000500 (PRSWEB_PHECODE174.1_Onco-iCOGS-ER-positive-BRCA_PRS-CS_UKB_20200608) PSS000570 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Breast cancer [female] OR: 1.674 [1.63, 1.719]
β: 0.515 (0.0137)
AUROC: 0.64 [0.634, 0.647] Nagelkerke's Pseudo-R²: 0.0463
Brier score: 0.0809
Odds Ratio (OR, top 1% vs. Rest): 3.64 [3.12, 4.25]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE174.1_Onco-iCOGS-ER-positive-BRCA_PRS-CS_UKB_20200608
PPM001255 PGS000570 (PRSWEB_PHECODE185_C3-PROSTATE_PRS-CS_MGI_20200608) PSS000552 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Cancer of prostate OR: 1.572 [1.465, 1.687]
β: 0.452 (0.0359)
AUROC: 0.622 [0.604, 0.639] Nagelkerke's Pseudo-R²: 0.0453
Brier score: 0.149
Odds Ratio (OR, top 1% vs. Rest): 2.66 [1.63, 4.34]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE185_C3-PROSTATE_PRS-CS_MGI_20200608
PPM001327 PGS000642 (PRSWEB_PHECODE202.2_GWAS-Catalog-r2019-05-03-X202.2_PT_UKB_20200608) PSS000580 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Non-Hodgkins lymphoma OR: 1.239 [1.16, 1.324]
β: 0.214 (0.0337)
AUROC: 0.547 [0.527, 0.566] Nagelkerke's Pseudo-R²: 0.0087
Brier score: 0.082
Odds Ratio (OR, top 1% vs. Rest): 2.05 [1.24, 3.4]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE202.2_GWAS-Catalog-r2019-05-03-X202.2_PT_UKB_20200608
PPM001059 PGS000374 (PRSWEB_PHECODE153_UKBB-SAIGE-HRC-X153_PT_MGI_20200608) PSS000540 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Colorectal cancer OR: 1.091 [1.004, 1.185]
β: 0.0872 (0.0423)
AUROC: 0.517 [0.493, 0.541] Nagelkerke's Pseudo-R²: 0.00134
Brier score: 0.083
Odds Ratio (OR, top 1% vs. Rest): 1.88 [0.99, 3.55]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE153_UKBB-SAIGE-HRC-X153_PT_MGI_20200608
PPM001069 PGS000384 (PRSWEB_PHECODE153.3_C3-RECTUM_PRS-CS_MGI_20200608) PSS000539 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Malignant neoplasm of rectum, rectosigmoid junction, and anus OR: 1.122 [1.001, 1.257]
β: 0.115 (0.058)
AUROC: 0.531 [0.495, 0.563] Nagelkerke's Pseudo-R²: 0.00251
Brier score: 0.0829
Odds Ratio (OR, top 1% vs. Rest): 1.02 [0.334, 3.14]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE153.3_C3-RECTUM_PRS-CS_MGI_20200608
PPM001094 PGS000409 (PRSWEB_PHECODE172.1_20001-1059_PRS-CS_MGI_20200608) PSS000543 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Melanomas of skin, dx or hx OR: 1.192 [1.126, 1.263]
β: 0.176 (0.0292)
AUROC: 0.547 [0.531, 0.563] Nagelkerke's Pseudo-R²: 0.0061
Brier score: 0.0966
Odds Ratio (OR, top 1% vs. Rest): 1.94 [1.25, 3.02]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE172.1_20001-1059_PRS-CS_MGI_20200608
PPM001097 PGS000412 (PRSWEB_PHECODE172.1_C3-MELANOMA-SKIN_P_5e-08_MGI_20200608) PSS000543 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Melanomas of skin, dx or hx OR: 1.414 [1.338, 1.495]
β: 0.347 (0.0282)
AUROC: 0.585 [0.569, 0.6] Nagelkerke's Pseudo-R²: 0.0236
Brier score: 0.0955
Odds Ratio (OR, top 1% vs. Rest): 3.26 [2.26, 4.7]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE172.1_C3-MELANOMA-SKIN_P_5e-08_MGI_20200608
PPM001129 PGS000444 (PRSWEB_PHECODE172.2_UKBB-SAIGE-HRC-X172.2_LASSOSUM_MGI_20200608) PSS000546 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Other non-epithelial cancer of skin OR: 1.399 [1.341, 1.46]
β: 0.336 (0.0216)
AUROC: 0.59 [0.578, 0.601] Nagelkerke's Pseudo-R²: 0.025
Brier score: 0.136
Odds Ratio (OR, top 1% vs. Rest): 3.5 [2.63, 4.65]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE172.2_UKBB-SAIGE-HRC-X172.2_LASSOSUM_MGI_20200608
PPM001165 PGS000480 (PRSWEB_PHECODE174.1_C50_P_5e-08_MGI_20200608) PSS000549 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Breast cancer [female] OR: 1.33 [1.253, 1.412]
β: 0.285 (0.0304)
AUROC: 0.576 [0.559, 0.593] Nagelkerke's Pseudo-R²: 0.0186
Brier score: 0.138
Odds Ratio (OR, top 1% vs. Rest): 1.91 [1.2, 3.03]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE174.1_C50_P_5e-08_MGI_20200608
PPM001223 PGS000538 (PRSWEB_PHECODE174.1_iCOGS-Overall-BRCA_PT_UKB_20200608) PSS000570 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Breast cancer [female] OR: 1.448 [1.411, 1.486]
β: 0.37 (0.0132)
AUROC: 0.602 [0.594, 0.609] Nagelkerke's Pseudo-R²: 0.025
Brier score: 0.0818
Odds Ratio (OR, top 1% vs. Rest): 2.78 [2.34, 3.3]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE174.1_iCOGS-Overall-BRCA_PT_UKB_20200608
PPM001262 PGS000577 (PRSWEB_PHECODE185_GWAS-Catalog-r2019-05-03-X185_P_5e-08_MGI_20200608) PSS000552 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Cancer of prostate OR: 1.756 [1.634, 1.886]
β: 0.563 (0.0366)
AUROC: 0.646 [0.627, 0.665] Nagelkerke's Pseudo-R²: 0.0678
Brier score: 0.147
Odds Ratio (OR, top 1% vs. Rest): 3.57 [2.29, 5.57]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE185_GWAS-Catalog-r2019-05-03-X185_P_5e-08_MGI_20200608
PPM001296 PGS000611 (PRSWEB_PHECODE189.2_GWAS-Catalog-r2019-05-03-X189.2_P_5e-08_UKB_20200608) PSS000576 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Cancer of bladder OR: 1.284 [1.211, 1.361]
β: 0.25 (0.0298)
AUROC: 0.567 [0.551, 0.584] Nagelkerke's Pseudo-R²: 0.0114
Brier score: 0.0821
Odds Ratio (OR, top 1% vs. Rest): 2.66 [1.79, 3.93]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE189.2_GWAS-Catalog-r2019-05-03-X189.2_P_5e-08_UKB_20200608

Evaluated Samples

PGS Sample Set ID
(PSS ID)
Phenotype Definitions and Methods Participant Follow-up Time Sample Numbers Age of Study Participants Sample Ancestry Additional Ancestry Description Cohort(s) Additional Sample/Cohort Information
PSS000554 PheCode:187; ICD9CM:186.0, 186.9, 187.1, 187.2, 187.3, 187.4, 187.5, 187.6, 187.7, 187.8, 187.9, 233.5, 233.6, 236.4, 236.5, 236.6, V10.45, V10.47, V10.48, V10.49; ICD10CM:C60, C60.0, C60.1, C60.2, C60.8, C60.9, C62, C62.0, C62.00, C62.01, C62.02, C62.1, C62.10, C62.11, C62.12, C62.9, C62.90, C62.91, C62.92, C63, C63.0, C63.00, C63.01, C63.02, C63.1, C63.10, C63.11, C63.12, C63.2, C63.7, C63.8, C63.9, D07.4, D07.6, D07.60, D07.61, D07.69, D40, D40.0, D40.1, D40.10, D40.11, D40.12, D40.8, D40.9
[
  • 137 cases
  • , 1,353 controls
]
European MGI
PSS000555 PheCode:189.2; ICD9CM:188.0, 188.1, 188.2, 188.3, 188.4, 188.5, 188.6, 188.7, 188.8, 188.9, 233.7, 236.7, 239.4, V10.51; ICD10CM:C67, C67.0, C67.1, C67.2, C67.3, C67.4, C67.5, C67.6, C67.7, C67.8, C67.9, D09.0, D41.4, D49.4
[
  • 789 cases
  • , 6,833 controls
]
European MGI
PSS000556 PheCode:190; ICD9CM:190.0, 190.1, 190.2, 190.3, 190.4, 190.5, 190.6, 190.7, 190.8, 190.9, 234.0, V10.84; ICD10CM:C69, C69.0, C69.00, C69.01, C69.02, C69.1, C69.10, C69.11, C69.12, C69.2, C69.20, C69.21, C69.22, C69.3, C69.30, C69.31, C69.32, C69.4, C69.40, C69.41, C69.42, C69.5, C69.50, C69.51, C69.52, C69.6, C69.60, C69.61, C69.62, C69.8, C69.80, C69.81, C69.82, C69.9, C69.90, C69.91, C69.92, D09.2, D09.20, D09.21, D09.22
[
  • 62 cases
  • , 610 controls
]
European MGI
PSS000557 PheCode:191.11; ICD9CM:191.0, 191.1, 191.2, 191.3, 191.4, 191.5, 191.6, 191.7, 191.8, 191.9, V10.85; ICD10CM:C71, C71.0, C71.1, C71.2, C71.3, C71.4, C71.5, C71.6, C71.7, C71.8, C71.9
[
  • 233 cases
  • , 2,330 controls
]
European MGI
PSS000558 PheCode:193; ICD9CM:193, V10.87; ICD10CM:C73
[
  • 389 cases
  • , 3,881 controls
]
European MGI
PSS000559 PheCode:201; ICD9CM:201.00, 201.01, 201.02, 201.03, 201.04, 201.05, 201.06, 201.07, 201.08, 201.10, 201.11, 201.12, 201.13, 201.14, 201.15, 201.16, 201.17, 201.18, 201.20, 201.21, 201.22, 201.23, 201.24, 201.25, 201.26, 201.27, 201.28, 201.40, 201.41, 201.42, 201.43, 201.44, 201.45, 201.46, 201.47, 201.48, 201.50, 201.51, 201.52, 201.53, 201.54, 201.55, 201.56, 201.57, 201.58, 201.60, 201.61, 201.62, 201.63, 201.64, 201.65, 201.66, 201.67, 201.68, 201.70, 201.71, 201.72, 201.73, 201.74, 201.75, 201.76, 201.77, 201.78, 201.90, 201.91, 201.92, 201.93, 201.94, 201.95, 201.96, 201.97, 201.98, V10.72; ICD10CM:C81, C81.0, C81.00, C81.01, C81.02, C81.03, C81.04, C81.05, C81.06, C81.07, C81.08, C81.09, C81.1, C81.10, C81.11, C81.12, C81.13, C81.14, C81.15, C81.16, C81.17, C81.18, C81.19, C81.2, C81.20, C81.21, C81.22, C81.23, C81.24, C81.25, C81.26, C81.27, C81.28, C81.29, C81.3, C81.30, C81.31, C81.32, C81.33, C81.34, C81.35, C81.36, C81.37, C81.38, C81.39, C81.4, C81.40, C81.41, C81.42, C81.43, C81.44, C81.45, C81.46, C81.47, C81.48, C81.49, C81.7, C81.70, C81.71, C81.72, C81.73, C81.74, C81.75, C81.76, C81.77, C81.78, C81.79, C81.9, C81.90, C81.91, C81.92, C81.93, C81.94, C81.95, C81.96, C81.97, C81.98, C81.99
[
  • 71 cases
  • , 704 controls
]
European MGI
PSS000560 PheCode:202.21; ICD9CM:202.00, 202.01, 202.02, 202.03, 202.04, 202.05, 202.06, 202.07, 202.08; ICD10CM:C82, C82.0, C82.00, C82.01, C82.02, C82.03, C82.04, C82.05, C82.06, C82.07, C82.08, C82.09, C82.1, C82.10, C82.11, C82.12, C82.13, C82.14, C82.15, C82.16, C82.17, C82.18, C82.19, C82.2, C82.20, C82.21, C82.22, C82.23, C82.24, C82.25, C82.26, C82.27, C82.28, C82.29, C82.3, C82.30, C82.31, C82.32, C82.33, C82.34, C82.35, C82.36, C82.37, C82.38, C82.39, C82.4, C82.40, C82.41, C82.42, C82.43, C82.44, C82.45, C82.46, C82.47, C82.48, C82.49, C82.5, C82.50, C82.51, C82.52, C82.53, C82.54, C82.55, C82.56, C82.57, C82.58, C82.59, C82.6, C82.60, C82.61, C82.62, C82.63, C82.64, C82.65, C82.66, C82.67, C82.68, C82.69, C82.8, C82.80, C82.81, C82.82, C82.83, C82.84, C82.85, C82.86, C82.87, C82.88, C82.89, C82.9, C82.90, C82.91, C82.92, C82.93, C82.94, C82.95, C82.96, C82.97, C82.98, C82.99
[
  • 296 cases
  • , 2,960 controls
]
European MGI
PSS000561 PheCode:204.12; ICD9CM:204.10, 204.11, 204.12; ICD10CM:C91.1, C91.10, C91.11, C91.12
[
  • 69 cases
  • , 687 controls
]
European MGI
PSS000562 PheCode:204.1; ICD9CM:204.00, 204.01, 204.02, 204.10, 204.11, 204.12, 204.20, 204.21, 204.22, 204.80, 204.81, 204.82, 204.90, 204.91, 204.92, V10.61; ICD10CM:C91, C91.0, C91.00, C91.01, C91.02, C91.1, C91.10, C91.11, C91.12, C91.3, C91.30, C91.31, C91.32, C91.4, C91.40, C91.41, C91.42, C91.5, C91.50, C91.51, C91.52, C91.6, C91.60, C91.61, C91.62,