Predicted Trait | |
Reported Trait | triglycerides |
Mapped Trait(s) | triglyceride measurement (EFO_0004530) |
Score Construction | |
PGS Name | GRS_TG |
Variants | |
Original Genome Build | NR |
Number of Variants | 32 |
Development Method | |
Name | Genome-wide significant SNPs |
Parameters | p < 5e-8 |
PGS Source | |
PGS Catalog Publication (PGP) ID | PGP000045 |
Citation (link to publication) | Johnson L et al. PLoS One (2015) |
Study Identifiers | Sample Numbers | Sample Ancestry |
---|---|---|
GWAS Catalog: GCST000758 EuropePMC: 20686565 |
96,598 individuals | European |
PGS Performance Metric ID (PPM ID) |
PGS Sample Set ID (PSS ID) |
Performance Source | Trait |
PGS Effect Sizes (per SD change) |
PGS Classification Metrics | Other Metrics | Covariates Included in the Model | PGS Performance: Other Relevant Information |
---|---|---|---|---|---|---|---|---|
PPM000165 | PSS000096 | PGP000045 Johnson L et al. PLoS One (2015) |
Reported Trait: Serum triglyceride (TG) levels | β: 0.047 | — | Beta (p-value): 0.526 | age, age^2, sex, GRS_HDL, GRS_LDL, GRS_TC | — |
PPM000166 | PSS000099 | PGP000045 Johnson L et al. PLoS One (2015) |
Reported Trait: Serum triglyceride (TG) levels | β: 0.5 | — | Beta (p-value): 1.09e-10 | age, age^2, sex, GRS_HDL, GRS_LDL, GRS_TC | Association (p-value; unadjusted for covariates) < 0.001 |
PPM000164 | PSS000097 | PGP000045 Johnson L et al. PLoS One (2015) |
Reported Trait: Serum triglyceride (TG) levels | β: 0.337 | — | Beta (p-value): 0.0107 | age, age^2, sex, GRS_HDL, GRS_LDL, GRS_TC | Association (p-value; unadjusted for covariates) < 0.001 |
PPM000163 | PSS000098 | PGP000045 Johnson L et al. PLoS One (2015) |
Reported Trait: Serum triglyceride (TG) levels | β: 0.464 | — | Beta (p-value): 1.71e-11 | age, age^2, sex, GRS_HDL, GRS_LDL, GRS_TC | Association (p-value; unadjusted for covariates) < 0.001 |
PGS Sample Set ID (PSS ID) |
Phenotype Definitions and Methods | Participant Follow-up Time | Sample Numbers | Age of Study Participants | Sample Ancestry | Additional Ancestry Description | Cohort(s) | Additional Sample/Cohort Information |
---|---|---|---|---|---|---|---|---|
PSS000097 | Lipid levels are represented in mg/dL, individuals on any lipid-lowering medication (n = 1,018) were omitted from all analyses. | — | 666 individuals, 50.15 % Male samples |
Mean = 61.5 years | East Asian | — | MESA | MESA Classic Cohort |
PSS000098 | Lipid levels are represented in mg/dL, individuals on any lipid-lowering medication (n = 1,018) were omitted from all analyses. | — | 2,063 individuals, 46.78 % Male samples |
Mean = 62.09 years | European | — | MESA | MESA Classic Cohort |
PSS000099 | Lipid levels are represented in mg/dL, individuals on any lipid-lowering medication (n = 1,018) were omitted from all analyses. | — | 1,256 individuals, 48.89 % Male samples |
Mean = 60.65 years | Hispanic or Latin American | — | MESA | MESA Classic Cohort |
PSS000096 | Lipid levels are represented in mg/dL, individuals on any lipid-lowering medication (n = 1,018) were omitted from all analyses. | — | 1,355 individuals, 46.2 % Male samples |
Mean = 61.68 years | African American or Afro-Caribbean | — | MESA | MESA Classic Cohort |