Polygenic Score (PGS) ID: PGS002217

Predicted Trait
Reported Trait Plays computer games
Mapped Trait(s) lifestyle measurement (EFO_0010724)
Additional Trait Information lifestyle and environment
Released in PGS Catalog: Jan. 10, 2022
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Score Details

Score Construction
PGS Name portability-ldpred2_play_computer
Development Method
Name LDpred2 (bigsnpr)
Parameters LDpred2-auto using HapMap3 variants
Variants
Original Genome Build GRCh37
Number of Variants 938,047
Effect Weight Type beta
PGS Source
PGS Catalog Publication (PGP) ID PGP000263
Citation (link to publication) Privé F et al. Am J Hum Genet (2022)
Ancestry Distribution
Score Development/Training
European: 100%
391,124 individuals (100%)
PGS Evaluation
European: 37.5%
African: 25%
East Asian: 12.5%
Greater Middle Eastern: 12.5%
South Asian: 12.5%
8 Sample Sets

Development Samples

Score Development/Training
Study Identifiers Sample Numbers Sample Ancestry Cohort(s) Phenotype Definitions & Methods Age of Study Participants Participant Follow-up Time Additional Ancestry Description Additional Sample/Cohort Information
— 391,124 individuals European UKB — — — UK (+ Ireland) —

Performance Metrics

Disclaimer: The performance metrics are displayed as reported by the source studies. It is important to note that metrics are not necessarily comparable with each other. For example, metrics depend on the sample characteristics (described by the PGS Catalog Sample Set [PSS] ID), phenotyping, and statistical modelling. Please refer to the source publication for additional guidance on performance.

PGS Performance
Metric ID (PPM) 		PGS Sample Set ID
(PSS) 		Performance Source Trait PGS Effect Sizes
(per SD change) 		Classification Metrics Other Metrics Covariates Included in the Model PGS Performance:
Other Relevant Information
PPM012583 PSS009483|
European Ancestry|
19,980 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Plays computer games — — Partial Correlation (partial-r): 0.1516 [0.138, 0.1651] sex, age, birth date, deprivation index, 16 PCs —
PPM012585 PSS008811|
European Ancestry|
6,626 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Plays computer games — — Partial Correlation (partial-r): 0.1404 [0.1167, 0.1639] sex, age, birth date, deprivation index, 16 PCs —
PPM012586 PSS008585|
Greater Middle Eastern Ancestry|
1,143 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Plays computer games — — Partial Correlation (partial-r): 0.0915 [0.0331, 0.1492] sex, age, birth date, deprivation index, 16 PCs —
PPM012587 PSS008363|
South Asian Ancestry|
6,108 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Plays computer games — — Partial Correlation (partial-r): 0.0871 [0.0621, 0.112] sex, age, birth date, deprivation index, 16 PCs —
PPM012588 PSS008140|
East Asian Ancestry|
1,782 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Plays computer games — — Partial Correlation (partial-r): 0.0686 [0.022, 0.1149] sex, age, birth date, deprivation index, 16 PCs —
PPM012589 PSS007927|
African Ancestry|
2,445 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Plays computer games — — Partial Correlation (partial-r): 0.0742 [0.0345, 0.1137] sex, age, birth date, deprivation index, 16 PCs —
PPM012590 PSS009031|
African Ancestry|
3,818 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Plays computer games — — Partial Correlation (partial-r): 0.0572 [0.0255, 0.0889] sex, age, birth date, deprivation index, 16 PCs —
PPM012584 PSS009257|
European Ancestry|
4,117 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Plays computer games — — Partial Correlation (partial-r): 0.159 [0.129, 0.1887] sex, age, birth date, deprivation index, 16 PCs —

Evaluated Samples

PGS Sample Set ID
(PSS) 		Phenotype Definitions and Methods Participant Follow-up Time Sample Numbers Age of Study Participants Sample Ancestry Additional Ancestry Description Cohort(s) Additional Sample/Cohort Information
PSS009031 — — 3,818 individuals — African unspecified Nigeria (West Africa) UKB —
PSS008585 — — 1,143 individuals — Greater Middle Eastern (Middle Eastern, North African or Persian) Iran (Middle East) UKB —
PSS009257 — — 4,117 individuals — European Poland (NE Europe) UKB —
PSS008811 — — 6,626 individuals — European Italy (South Europe) UKB —
PSS008140 — — 1,782 individuals — East Asian China (East Asia) UKB —
PSS008363 — — 6,108 individuals — South Asian India (South Asia) UKB —
PSS009483 — — 19,980 individuals — European UK (+ Ireland) UKB —
PSS007927 — — 2,445 individuals — African American or Afro-Caribbean Carribean UKB —