Trait: angina pectoris

Experimental Factor Ontology (EFO) Information
Identifier EFO_0003913
Description
  • The symptom of paroxysmal pain consequent to MYOCARDIAL ISCHEMIA usually of distinctive character, location and radiation. It is thought to be provoked by a transient stressful situation during which the oxygen requirements of the MYOCARDIUM exceed that supplied by the CORONARY CIRCULATION.
Trait category
Other trait
Synonyms 4 synonyms
  • Angor Pectoris
  • Stenocardia
  • Stenocardias
  • stable angina
Mapped term(s) 7 mapped terms
  • ICD10:I20
  • ICD9:413
  • MSH:D000787
  • MSH:D060050
  • NCIt:C66914
  • SNOMEDCT:194828000
  • SNOMEDCT:233819005

Associated Polygenic Score(s)

Polygenic Score (PGS) ID PGS Name PGS Publication (PGP) ID Reported Trait Mapped Trait(s) (Ontology) Number of Variants PGS Scoring File (FTP Link)
PGS000703 HC132 PGP000128 Sinnott-Armstrong N et al. Nat Genet (2021) Angina angina pectoris 183,692 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000703/ScoringFiles/PGS000703.txt.gz - Check Terms/Licenses

PGS Performance Metrics

Disclaimer: The performance metrics are displayed as reported by the source studies. It is important to note that metrics are not necessarily comparable with each other. For example, metrics depend on the sample characteristics (described by the PGS Catalog Sample Set [PSS] ID), phenotyping, and statistical modelling. Please refer to the source publication for additional guidance on performance.

PGS Performance Metric ID
(PPM ID)
Evaluated Score PGS Sample Set ID
(PSS ID)
Performance Source Trait PGS Effect Sizes
(per SD change)
PGS Classification Metrics Other Metrics Covariates Included in the Model PGS Performance: Other Relevant Information
PPM001595 PGS000703
(HC132)
PSS000794 PGP000128 Sinnott-Armstrong N et al. (2021) Reported Trait: Angina AUROC: 0.59262 Age, sex, PCs(1-10)

Evaluated Samples

PGS Sample Set ID
(PSS ID)
Phenotype Definitions and Methods Participant Follow-up Time Sample Numbers Age of Study Participants Sample Ancestry Additional Ancestry Description Cohort(s) Additional Sample/Cohort Information
PSS000794 87,413 individuals European UKB