Trait: angina pectoris

Experimental Factor Ontology (EFO) Information
Identifier EFO_0003913
Description The symptom of paroxysmal pain consequent to MYOCARDIAL ISCHEMIA usually of distinctive character, location and radiation. It is thought to be provoked by a transient stressful situation during which the oxygen requirements of the MYOCARDIUM exceed that supplied by the CORONARY CIRCULATION.
Trait category
Cardiovascular disease
Synonyms 5 synonyms
  • Angor Pectoris
  • Stenocardia
  • Stenocardias
  • angina
  • stable angina
Mapped terms 8 mapped terms
  • ICD10:I20
  • ICD9:413
  • MESH:D000787
  • MESH:D060050
  • MedDRA:10002383
  • NCIt:C66914
  • SNOMEDCT:194828000
  • SNOMEDCT:233819005

Associated Polygenic Score(s)

Filter PGS by Participant Ancestry
Individuals included in:
G - Source of Variant Associations (GWAS)
D - Score Development/Training
E - PGS Evaluation
List of ancestries includes:
Display options:
Ancestry legend
Multi-ancestry (including European)
Multi-ancestry (excluding European)
African
East Asian
South Asian
Additional Asian Ancestries
European
Greater Middle Eastern
Hispanic or Latin American
Additional Diverse Ancestries
Not Reported
Polygenic Score ID & Name PGS Publication ID (PGP) Reported Trait Mapped Trait(s) (Ontology) Number of Variants Ancestry distribution
GWAS
Dev
Eval
 Scoring File (FTP Link)
PGS000703
(HC132)
 PGP000128 |
Sinnott-Armstrong N et al. Nat Genet (2021)
 Angina angina pectoris 183,692
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000703/ScoringFiles/PGS000703.txt.gz - Check Terms/Licenses
PGS001260
(GBE_HC132)
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Angina angina pectoris 2,562
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001260/ScoringFiles/PGS001260.txt.gz
PGS001261
(GBE_HC937)
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Angina pectoris (time-to-event) angina pectoris 2,524
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001261/ScoringFiles/PGS001261.txt.gz
PGS001262
(GBE_BIN_FC2006150)
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Vascular/heart problems diagnosed by doctor Angina angina pectoris 1,852
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001262/ScoringFiles/PGS001262.txt.gz
PGS004457
(disease.I20.score)
 PGP000561 |
Jung H et al. Commun Biol (2024)
 I20 (Angina pectoris) angina pectoris 1,059,939
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004457/ScoringFiles/PGS004457.txt.gz
PGS004527
(meta.I20.score)
 PGP000561 |
Jung H et al. Commun Biol (2024)
 I20 (Angina pectoris) angina pectoris 1,059,939
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004527/ScoringFiles/PGS004527.txt.gz
PGS005047
(Phe_411_3_ldpred_AFRss_afrld)
 PGP000679 |
Gunn S et al. HGG Adv (2024)
 Angina pectoris (PheCode 411.3) angina pectoris 1,286,612
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005047/ScoringFiles/PGS005047.txt.gz
PGS005048
(Phe_411_3_ldpred_EURss_eurld)
 PGP000679 |
Gunn S et al. HGG Adv (2024)
 Angina pectoris (PheCode 411.3) angina pectoris 1,286,612
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005048/ScoringFiles/PGS005048.txt.gz
PGS005049
(Phe_411_3_ldpred_HISss_amrld)
 PGP000679 |
Gunn S et al. HGG Adv (2024)
 Angina pectoris (PheCode 411.3) angina pectoris 1,286,612
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005049/ScoringFiles/PGS005049.txt.gz
PGS005050
(Phe_411_3_ldpred_METAss_afrld)
 PGP000679 |
Gunn S et al. HGG Adv (2024)
 Angina pectoris (PheCode 411.3) angina pectoris 1,286,612
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005050/ScoringFiles/PGS005050.txt.gz
PGS005051
(Phe_411_3_ldpred_METAss_amrld)
 PGP000679 |
Gunn S et al. HGG Adv (2024)
 Angina pectoris (PheCode 411.3) angina pectoris 1,286,612
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005051/ScoringFiles/PGS005051.txt.gz
PGS005052
(Phe_411_3_ldpred_METAss_eurld)
 PGP000679 |
Gunn S et al. HGG Adv (2024)
 Angina pectoris (PheCode 411.3) angina pectoris 1,286,612
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005052/ScoringFiles/PGS005052.txt.gz
PGS005053
(Phe_411_3_prscs_AFRss_afrld)
 PGP000679 |
Gunn S et al. HGG Adv (2024)
 Angina pectoris (PheCode 411.3) angina pectoris 1,273,665
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005053/ScoringFiles/PGS005053.txt.gz
PGS005054
(Phe_411_3_prscs_EURss_eurld)
 PGP000679 |
Gunn S et al. HGG Adv (2024)
 Angina pectoris (PheCode 411.3) angina pectoris 1,273,665
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005054/ScoringFiles/PGS005054.txt.gz
PGS005055
(Phe_411_3_prscs_HISss_amrld)
 PGP000679 |
Gunn S et al. HGG Adv (2024)
 Angina pectoris (PheCode 411.3) angina pectoris 1,273,665
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005055/ScoringFiles/PGS005055.txt.gz
PGS005056
(Phe_411_3_prscs_METAss_afrld)
 PGP000679 |
Gunn S et al. HGG Adv (2024)
 Angina pectoris (PheCode 411.3) angina pectoris 1,273,665
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005056/ScoringFiles/PGS005056.txt.gz
PGS005057
(Phe_411_3_prscs_METAss_amrld)
 PGP000679 |
Gunn S et al. HGG Adv (2024)
 Angina pectoris (PheCode 411.3) angina pectoris 1,273,665
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005057/ScoringFiles/PGS005057.txt.gz
PGS005058
(Phe_411_3_prscs_METAss_eurld)
 PGP000679 |
Gunn S et al. HGG Adv (2024)
 Angina pectoris (PheCode 411.3) angina pectoris 1,273,665
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005058/ScoringFiles/PGS005058.txt.gz
PGS005059
(Phe_411_3_prscsx_METAweight)
 PGP000679 |
Gunn S et al. HGG Adv (2024)
 Angina pectoris (PheCode 411.3) angina pectoris 1,273,891
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005059/ScoringFiles/PGS005059.txt.gz

Performance Metrics

Disclaimer: The performance metrics are displayed as reported by the source studies. It is important to note that metrics are not necessarily comparable with each other. For example, metrics depend on the sample characteristics (described by the PGS Catalog Sample Set [PSS] ID), phenotyping, and statistical modelling. Please refer to the source publication for additional guidance on performance.

PGS Performance
Metric ID (PPM) 		Evaluated Score PGS Sample Set ID
(PSS) 		Performance Source Trait PGS Effect Sizes
(per SD change) 		Classification Metrics Other Metrics Covariates Included in the Model PGS Performance:
Other Relevant Information
PPM001595 PGS000703
(HC132)
 PSS000794|
European Ancestry|
87,413 individuals
 PGP000128 |
Sinnott-Armstrong N et al. Nat Genet (2021)
 Reported Trait: Angina — AUROC: 0.59262 — Age, sex, PCs(1-10) —
PPM008805 PGS001260
(GBE_HC132)
 PSS004263|
African Ancestry|
6,497 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: Angina — AUROC: 0.74858 [0.72225, 0.7749] R²: 0.10317
Incremental AUROC (full-covars): 0.00581
PGS R2 (no covariates): 0.0021
PGS AUROC (no covariates): 0.53477 [0.50036, 0.56918]		 age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM008806 PGS001260
(GBE_HC132)
 PSS004264|
East Asian Ancestry|
1,704 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: Angina — AUROC: 0.79053 [0.72587, 0.85519] R²: 0.12393
Incremental AUROC (full-covars): 0.00849
PGS R2 (no covariates): 0.01465
PGS AUROC (no covariates): 0.60534 [0.52229, 0.68839]		 age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM008807 PGS001260
(GBE_HC132)
 PSS004265|
European Ancestry|
24,905 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: Angina — AUROC: 0.74298 [0.72979, 0.75617] R²: 0.1154
Incremental AUROC (full-covars): 0.00783
PGS R2 (no covariates): 0.01185
PGS AUROC (no covariates): 0.58108 [0.56544, 0.59672]		 age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM008808 PGS001260
(GBE_HC132)
 PSS004266|
South Asian Ancestry|
7,831 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: Angina — AUROC: 0.74658 [0.73013, 0.76304] R²: 0.14735
Incremental AUROC (full-covars): 0.00443
PGS R2 (no covariates): 0.00579
PGS AUROC (no covariates): 0.54578 [0.52572, 0.56585]		 age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM008809 PGS001260
(GBE_HC132)
 PSS004267|
European Ancestry|
67,425 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: Angina — AUROC: 0.74167 [0.73419, 0.74914] R²: 0.11464
Incremental AUROC (full-covars): 0.01108
PGS R2 (no covariates): 0.01112
PGS AUROC (no covariates): 0.57435 [0.565, 0.58369]		 age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM008810 PGS001261
(GBE_HC937)
 PSS004716|
African Ancestry|
6,497 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: TTE angina pectoris — AUROC: 0.74888 [0.72237, 0.77539] R²: 0.10279
Incremental AUROC (full-covars): 0.00677
PGS R2 (no covariates): 0.00325
PGS AUROC (no covariates): 0.54251 [0.50735, 0.57767]		 age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM008811 PGS001261
(GBE_HC937)
 PSS004717|
East Asian Ancestry|
1,704 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: TTE angina pectoris — AUROC: 0.79649 [0.73626, 0.85672] R²: 0.13398
Incremental AUROC (full-covars): 0.00843
PGS R2 (no covariates): 0.01725
PGS AUROC (no covariates): 0.61522 [0.5356, 0.69485]		 age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM008812 PGS001261
(GBE_HC937)
 PSS004718|
European Ancestry|
24,905 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: TTE angina pectoris — AUROC: 0.74852 [0.73543, 0.76161] R²: 0.12116
Incremental AUROC (full-covars): 0.00796
PGS R2 (no covariates): 0.01228
PGS AUROC (no covariates): 0.58233 [0.56671, 0.59794]		 age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM008813 PGS001261
(GBE_HC937)
 PSS004719|
South Asian Ancestry|
7,831 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: TTE angina pectoris — AUROC: 0.74714 [0.73072, 0.76355] R²: 0.14768
Incremental AUROC (full-covars): 0.00461
PGS R2 (no covariates): 0.00594
PGS AUROC (no covariates): 0.54707 [0.52705, 0.56709]		 age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM008814 PGS001261
(GBE_HC937)
 PSS004720|
European Ancestry|
67,425 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: TTE angina pectoris — AUROC: 0.742 [0.73458, 0.74942] R²: 0.11586
Incremental AUROC (full-covars): 0.01139
PGS R2 (no covariates): 0.01162
PGS AUROC (no covariates): 0.57494 [0.56568, 0.5842]		 age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM008815 PGS001262
(GBE_BIN_FC2006150)
 PSS003854|
African Ancestry|
3,985 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: Vascular/heart problems diagnosed by doctor Angina — AUROC: 0.82431 [0.7951, 0.85352] R²: 0.18928
Incremental AUROC (full-covars): 0.00472
PGS R2 (no covariates): 0.00244
PGS AUROC (no covariates): 0.54151 [0.4965, 0.58652]		 age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM008816 PGS001262
(GBE_BIN_FC2006150)
 PSS003855|
East Asian Ancestry|
1,317 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: Vascular/heart problems diagnosed by doctor Angina — AUROC: 0.81573 [0.71999, 0.91148] R²: 0.18878
Incremental AUROC (full-covars): 0.01113
PGS R2 (no covariates): 0.00409
PGS AUROC (no covariates): 0.54123 [0.41196, 0.67049]		 age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM008817 PGS001262
(GBE_BIN_FC2006150)
 PSS003856|
European Ancestry|
18,868 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: Vascular/heart problems diagnosed by doctor Angina — AUROC: 0.78043 [0.76461, 0.79624] R²: 0.14388
Incremental AUROC (full-covars): 0.00599
PGS R2 (no covariates): 0.01288
PGS AUROC (no covariates): 0.58632 [0.56598, 0.60667]		 age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM008818 PGS001262
(GBE_BIN_FC2006150)
 PSS003857|
South Asian Ancestry|
5,473 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: Vascular/heart problems diagnosed by doctor Angina — AUROC: 0.8083 [0.78794, 0.82865] R²: 0.2132
Incremental AUROC (full-covars): 0.00447
PGS R2 (no covariates): 0.00511
PGS AUROC (no covariates): 0.54847 [0.52094, 0.57599]		 age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM008819 PGS001262
(GBE_BIN_FC2006150)
 PSS003858|
European Ancestry|
49,472 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: Vascular/heart problems diagnosed by doctor Angina — AUROC: 0.80729 [0.79886, 0.81571] R²: 0.17468
Incremental AUROC (full-covars): 0.0098
PGS R2 (no covariates): 0.01304
PGS AUROC (no covariates): 0.58683 [0.57429, 0.59937]		 age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM020572 PGS004457
(disease.I20.score)
 PSS011364|
European Ancestry|
56,192 individuals
 PGP000561 |
Jung H et al. Commun Biol (2024)
 Reported Trait: I20 (Angina pectoris) OR: 1.30968 — — — —
PPM020642 PGS004527
(meta.I20.score)
 PSS011364|
European Ancestry|
56,192 individuals
 PGP000561 |
Jung H et al. Commun Biol (2024)
 Reported Trait: I20 (Angina pectoris) OR: 1.42944 — — — —
PPM021920 PGS005047
(Phe_411_3_ldpred_AFRss_afrld)
 PSS011809|
Hispanic or Latin American Ancestry|
8,114 individuals
 PGP000679 |
Gunn S et al. HGG Adv (2024)
 Reported Trait: Angina pectoris OR: 0.986 [0.85, 1.15] C-index: 0.79766 — age, sex, 20 PCs —
PPM021926 PGS005047
(Phe_411_3_ldpred_AFRss_afrld)
 PSS011819|
European Ancestry|
30,750 individuals
 PGP000679 |
Gunn S et al. HGG Adv (2024)
 Reported Trait: Angina pectoris OR: 1.061 [1.01, 1.11] C-index: 0.75308 — age, sex, 20 PCs —
PPM021932 PGS005047
(Phe_411_3_ldpred_AFRss_afrld)
 PSS011799|
African Ancestry|
10,445 individuals
 PGP000679 |
Gunn S et al. HGG Adv (2024)
 Reported Trait: Angina pectoris OR: 1.135 [1.02, 1.26] C-index: 0.74686 — age, sex, 20 PCs —
PPM021922 PGS005048
(Phe_411_3_ldpred_EURss_eurld)
 PSS011809|
Hispanic or Latin American Ancestry|
8,114 individuals
 PGP000679 |
Gunn S et al. HGG Adv (2024)
 Reported Trait: Angina pectoris OR: 1.284 [1.06, 1.55] C-index: 0.7976 — age, sex, 20 PCs —
PPM021934 PGS005048
(Phe_411_3_ldpred_EURss_eurld)
 PSS011799|
African Ancestry|
10,445 individuals
 PGP000679 |
Gunn S et al. HGG Adv (2024)
 Reported Trait: Angina pectoris OR: 1.156 [0.98, 1.36] C-index: 0.74595 — age, sex, 20 PCs —
PPM021928 PGS005048
(Phe_411_3_ldpred_EURss_eurld)
 PSS011819|
European Ancestry|
30,750 individuals
 PGP000679 |
Gunn S et al. HGG Adv (2024)
 Reported Trait: Angina pectoris OR: 1.487 [1.41, 1.56] C-index: 0.76688 — age, sex, 20 PCs —
PPM021927 PGS005049
(Phe_411_3_ldpred_HISss_amrld)
 PSS011819|
European Ancestry|
30,750 individuals
 PGP000679 |
Gunn S et al. HGG Adv (2024)
 Reported Trait: Angina pectoris OR: 1.115 [1.07, 1.17] C-index: 0.75404 — age, sex, 20 PCs —
PPM021921 PGS005049
(Phe_411_3_ldpred_HISss_amrld)
 PSS011809|
Hispanic or Latin American Ancestry|
8,114 individuals
 PGP000679 |
Gunn S et al. HGG Adv (2024)
 Reported Trait: Angina pectoris OR: 1.17 [1.04, 1.32] C-index: 0.7981 — age, sex, 20 PCs —
PPM021933 PGS005049
(Phe_411_3_ldpred_HISss_amrld)
 PSS011799|
African Ancestry|
10,445 individuals
 PGP000679 |
Gunn S et al. HGG Adv (2024)
 Reported Trait: Angina pectoris OR: 1.102 [0.99, 1.22] C-index: 0.74684 — age, sex, 20 PCs —
PPM021917 PGS005050
(Phe_411_3_ldpred_METAss_afrld)
 PSS011809|
Hispanic or Latin American Ancestry|
8,114 individuals
 PGP000679 |
Gunn S et al. HGG Adv (2024)
 Reported Trait: Angina pectoris OR: 1.252 [1.11, 1.41] C-index: 0.799 — age, sex, 20 PCs —
PPM021923 PGS005050
(Phe_411_3_ldpred_METAss_afrld)
 PSS011819|
European Ancestry|
30,750 individuals
 PGP000679 |
Gunn S et al. HGG Adv (2024)
 Reported Trait: Angina pectoris OR: 1.445 [1.37, 1.52] C-index: 0.76508 — age, sex, 20 PCs —
PPM021929 PGS005050
(Phe_411_3_ldpred_METAss_afrld)
 PSS011799|
African Ancestry|
10,445 individuals
 PGP000679 |
Gunn S et al. HGG Adv (2024)
 Reported Trait: Angina pectoris OR: 1.276 [1.15, 1.42] C-index: 0.74997 — age, sex, 20 PCs —
PPM021918 PGS005051
(Phe_411_3_ldpred_METAss_amrld)
 PSS011809|
Hispanic or Latin American Ancestry|
8,114 individuals
 PGP000679 |
Gunn S et al. HGG Adv (2024)
 Reported Trait: Angina pectoris OR: 1.256 [1.11, 1.42] C-index: 0.79901 — age, sex, 20 PCs —
PPM021924 PGS005051
(Phe_411_3_ldpred_METAss_amrld)
 PSS011819|
European Ancestry|
30,750 individuals
 PGP000679 |
Gunn S et al. HGG Adv (2024)
 Reported Trait: Angina pectoris OR: 1.455 [1.38, 1.53] C-index: 0.76546 — age, sex, 20 PCs —
PPM021930 PGS005051
(Phe_411_3_ldpred_METAss_amrld)
 PSS011799|
African Ancestry|
10,445 individuals
 PGP000679 |
Gunn S et al. HGG Adv (2024)
 Reported Trait: Angina pectoris OR: 1.254 [1.13, 1.39] C-index: 0.74981 — age, sex, 20 PCs —
PPM021919 PGS005052
(Phe_411_3_ldpred_METAss_eurld)
 PSS011809|
Hispanic or Latin American Ancestry|
8,114 individuals
 PGP000679 |
Gunn S et al. HGG Adv (2024)
 Reported Trait: Angina pectoris OR: 1.212 [1.07, 1.37] C-index: 0.79845 — age, sex, 20 PCs —
PPM021925 PGS005052
(Phe_411_3_ldpred_METAss_eurld)
 PSS011819|
European Ancestry|
30,750 individuals
 PGP000679 |
Gunn S et al. HGG Adv (2024)
 Reported Trait: Angina pectoris OR: 1.491 [1.42, 1.57] C-index: 0.76625 — age, sex, 20 PCs —
PPM021931 PGS005052
(Phe_411_3_ldpred_METAss_eurld)
 PSS011799|
African Ancestry|
10,445 individuals
 PGP000679 |
Gunn S et al. HGG Adv (2024)
 Reported Trait: Angina pectoris OR: 1.187 [1.06, 1.33] C-index: 0.7476 — age, sex, 20 PCs —
PPM021821 PGS005053
(Phe_411_3_prscs_AFRss_afrld)
 PSS011809|
Hispanic or Latin American Ancestry|
8,114 individuals
 PGP000679 |
Gunn S et al. HGG Adv (2024)
 Reported Trait: Angina pectoris OR: 0.967 [0.8, 1.17] C-index: 0.7976 — age, sex, 20 PCs —
PPM021828 PGS005053
(Phe_411_3_prscs_AFRss_afrld)
 PSS011819|
European Ancestry|
30,750 individuals
 PGP000679 |
Gunn S et al. HGG Adv (2024)
 Reported Trait: Angina pectoris OR: 1.041 [0.99, 1.09] C-index: 0.75283 — age, sex, 20 PCs —
PPM021835 PGS005053
(Phe_411_3_prscs_AFRss_afrld)
 PSS011799|
African Ancestry|
10,445 individuals
 PGP000679 |
Gunn S et al. HGG Adv (2024)
 Reported Trait: Angina pectoris OR: 1.141 [1.02, 1.27] C-index: 0.74669 — age, sex, 20 PCs —
PPM021823 PGS005054
(Phe_411_3_prscs_EURss_eurld)
 PSS011809|
Hispanic or Latin American Ancestry|
8,114 individuals
 PGP000679 |
Gunn S et al. HGG Adv (2024)
 Reported Trait: Angina pectoris OR: 1.249 [1.08, 1.45] C-index: 0.79798 — age, sex, 20 PCs —
PPM021830 PGS005054
(Phe_411_3_prscs_EURss_eurld)
 PSS011819|
European Ancestry|
30,750 individuals
 PGP000679 |
Gunn S et al. HGG Adv (2024)
 Reported Trait: Angina pectoris OR: 1.43 [1.36, 1.5] C-index: 0.7656 — age, sex, 20 PCs —
PPM021837 PGS005054
(Phe_411_3_prscs_EURss_eurld)
 PSS011799|
African Ancestry|
10,445 individuals
 PGP000679 |
Gunn S et al. HGG Adv (2024)
 Reported Trait: Angina pectoris OR: 1.117 [0.98, 1.28] C-index: 0.7457 — age, sex, 20 PCs —
PPM021829 PGS005055
(Phe_411_3_prscs_HISss_amrld)
 PSS011819|
European Ancestry|
30,750 individuals
 PGP000679 |
Gunn S et al. HGG Adv (2024)
 Reported Trait: Angina pectoris OR: 1.108 [1.06, 1.16] C-index: 0.75396 — age, sex, 20 PCs —
PPM021836 PGS005055
(Phe_411_3_prscs_HISss_amrld)
 PSS011799|
African Ancestry|
10,445 individuals
 PGP000679 |
Gunn S et al. HGG Adv (2024)
 Reported Trait: Angina pectoris OR: 1.13 [1.0, 1.28] C-index: 0.74724 — age, sex, 20 PCs —
PPM021822 PGS005055
(Phe_411_3_prscs_HISss_amrld)
 PSS011809|
Hispanic or Latin American Ancestry|
8,114 individuals
 PGP000679 |
Gunn S et al. HGG Adv (2024)
 Reported Trait: Angina pectoris OR: 1.222 [1.07, 1.4] C-index: 0.79814 — age, sex, 20 PCs —
PPM021818 PGS005056
(Phe_411_3_prscs_METAss_afrld)
 PSS011809|
Hispanic or Latin American Ancestry|
8,114 individuals
 PGP000679 |
Gunn S et al. HGG Adv (2024)
 Reported Trait: Angina pectoris OR: 1.213 [1.08, 1.36] C-index: 0.79911 — age, sex, 20 PCs —
PPM021825 PGS005056
(Phe_411_3_prscs_METAss_afrld)
 PSS011819|
European Ancestry|
30,750 individuals
 PGP000679 |
Gunn S et al. HGG Adv (2024)
 Reported Trait: Angina pectoris OR: 1.381 [1.32, 1.45] C-index: 0.76261 — age, sex, 20 PCs —
PPM021832 PGS005056
(Phe_411_3_prscs_METAss_afrld)
 PSS011799|
African Ancestry|
10,445 individuals
 PGP000679 |
Gunn S et al. HGG Adv (2024)
 Reported Trait: Angina pectoris OR: 1.233 [1.11, 1.37] C-index: 0.74892 — age, sex, 20 PCs —
PPM021819 PGS005057
(Phe_411_3_prscs_METAss_amrld)
 PSS011809|
Hispanic or Latin American Ancestry|
8,114 individuals
 PGP000679 |
Gunn S et al. HGG Adv (2024)
 Reported Trait: Angina pectoris OR: 1.25 [1.11, 1.41] C-index: 0.7999 — age, sex, 20 PCs —
PPM021826 PGS005057
(Phe_411_3_prscs_METAss_amrld)
 PSS011819|
European Ancestry|
30,750 individuals
 PGP000679 |
Gunn S et al. HGG Adv (2024)
 Reported Trait: Angina pectoris OR: 1.479 [1.41, 1.56] C-index: 0.76637 — age, sex, 20 PCs —
PPM021833 PGS005057
(Phe_411_3_prscs_METAss_amrld)
 PSS011799|
African Ancestry|
10,445 individuals
 PGP000679 |
Gunn S et al. HGG Adv (2024)
 Reported Trait: Angina pectoris OR: 1.251 [1.12, 1.39] C-index: 0.74982 — age, sex, 20 PCs —
PPM021820 PGS005058
(Phe_411_3_prscs_METAss_eurld)
 PSS011809|
Hispanic or Latin American Ancestry|
8,114 individuals
 PGP000679 |
Gunn S et al. HGG Adv (2024)
 Reported Trait: Angina pectoris OR: 1.233 [1.08, 1.4] C-index: 0.79865 — age, sex, 20 PCs —
PPM021827 PGS005058
(Phe_411_3_prscs_METAss_eurld)
 PSS011819|
European Ancestry|
30,750 individuals
 PGP000679 |
Gunn S et al. HGG Adv (2024)
 Reported Trait: Angina pectoris OR: 1.452 [1.38, 1.53] C-index: 0.7656 — age, sex, 20 PCs —
PPM021834 PGS005058
(Phe_411_3_prscs_METAss_eurld)
 PSS011799|
African Ancestry|
10,445 individuals
 PGP000679 |
Gunn S et al. HGG Adv (2024)
 Reported Trait: Angina pectoris OR: 1.215 [1.08, 1.37] C-index: 0.74742 — age, sex, 20 PCs —
PPM021824 PGS005059
(Phe_411_3_prscsx_METAweight)
 PSS011809|
Hispanic or Latin American Ancestry|
8,114 individuals
 PGP000679 |
Gunn S et al. HGG Adv (2024)
 Reported Trait: Angina pectoris OR: 1.198 [1.07, 1.35] C-index: 0.79851 — age, sex, 20 PCs —
PPM021838 PGS005059
(Phe_411_3_prscsx_METAweight)
 PSS011799|
African Ancestry|
10,445 individuals
 PGP000679 |
Gunn S et al. HGG Adv (2024)
 Reported Trait: Angina pectoris OR: 1.179 [1.07, 1.3] C-index: 0.74791 — age, sex, 20 PCs —
PPM021831 PGS005059
(Phe_411_3_prscsx_METAweight)
 PSS011819|
European Ancestry|
30,750 individuals
 PGP000679 |
Gunn S et al. HGG Adv (2024)
 Reported Trait: Angina pectoris OR: 1.412 [1.35, 1.48] C-index: 0.76435 — age, sex, 20 PCs —

Evaluated Samples

PGS Sample Set ID
(PSS) 		Phenotype Definitions and Methods Participant Follow-up Time Sample Numbers Age of Study Participants Sample Ancestry Additional Ancestry Description Cohort(s) Additional Sample/Cohort Information
PSS004716 — —
[
  • 275 cases
  • , 6,222 controls
]
 — African unspecified — UKB —
PSS004717 — —
[
  • 45 cases
  • , 1,659 controls
]
 — East Asian — UKB —
PSS004718 — —
[
  • 1,336 cases
  • , 23,569 controls
]
 — European non-white British ancestry UKB —
PSS004719 — —
[
  • 878 cases
  • , 6,953 controls
]
 — South Asian — UKB —
PSS004720 — —
[
  • 3,997 cases
  • , 63,428 controls
]
 — European white British ancestry UKB Testing cohort (heldout set)
PSS003854 — —
[
  • 161 cases
  • , 3,824 controls
]
 — African unspecified — UKB —
PSS003855 — —
[
  • 21 cases
  • , 1,296 controls
]
 — East Asian — UKB —
PSS003856 — —
[
  • 784 cases
  • , 18,084 controls
]
 — European non-white British ancestry UKB —
PSS003857 — —
[
  • 430 cases
  • , 5,043 controls
]
 — South Asian — UKB —
PSS003858 — —
[
  • 2,098 cases
  • , 47,374 controls
]
 — European white British ancestry UKB Testing cohort (heldout set)
PSS011364 — — 56,192 individuals — European — UKB —
PSS011799 — —
[
  • 505 cases
  • , 9,940 controls
]
 — African American or Afro-Caribbean — AllofUs —
PSS004263 — —
[
  • 281 cases
  • , 6,216 controls
]
 — African unspecified — UKB —
PSS004264 — —
[
  • 41 cases
  • , 1,663 controls
]
 — East Asian — UKB —
PSS004265 — —
[
  • 1,341 cases
  • , 23,564 controls
]
 — European non-white British ancestry UKB —
PSS004266 — —
[
  • 876 cases
  • , 6,955 controls
]
 — South Asian — UKB —
PSS004267 — —
[
  • 3,927 cases
  • , 63,498 controls
]
 — European white British ancestry UKB Testing cohort (heldout set)
PSS011809 — —
[
  • 371 cases
  • , 7,743 controls
]
 — Hispanic or Latin American — AllofUs —
PSS000794 — — 87,413 individuals — European — UKB —
PSS011819 — —
[
  • 2,154 cases
  • , 28,596 controls
]
 — European — AllofUs —