Trait: serum non-albumin protein measurement

Experimental Factor Ontology (EFO) Information
Identifier EFO_0004568
Description
  • The measurement of the non-albumin portion of blood protein (globulin) in serum
Trait category
Other measurement

Associated Polygenic Score(s)

Polygenic Score (PGS) ID PGS Name PGS Publication (PGP) ID Reported Trait Mapped Trait(s) (Ontology) Number of Variants PGS Scoring File (FTP Link)
PGS000691 snpnet.Non_albumin_protein PGP000128 Sinnott-Armstrong N et al. Nat Genet (2021) Non-albumin protein [g/L] serum non-albumin protein measurement 18,670 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000691/ScoringFiles/PGS000691.txt.gz - Check Terms/Licenses

PGS Performance Metrics

Disclaimer: The performance metrics are displayed as reported by the source studies. It is important to note that metrics are not necessarily comparable with each other. For example, metrics depend on the sample characteristics (described by the PGS Catalog Sample Set [PSS] ID), phenotyping, and statistical modelling. Please refer to the source publication for additional guidance on performance.

PGS Performance Metric ID
(PPM ID) 		Evaluated Score PGS Sample Set ID
(PSS ID) 		Performance Source Trait PGS Effect Sizes
(per SD change) 		PGS Classification Metrics Other Metrics Covariates Included in the Model PGS Performance: Other Relevant Information
PPM001559 PGS000691
(snpnet.Non_albumin_protein)
 PSS000733 PGP000128 Sinnott-Armstrong N et al. (2021) Reported Trait: Non-albumin protein [g/L] — — R²: 0.12321
Spearman's ρ: 0.311		 Age, sex, PCs(1-40) —
PPM001524 PGS000691
(snpnet.Non_albumin_protein)
 PSS000732 PGP000128 Sinnott-Armstrong N et al. (2021) Reported Trait: Non-albumin protein [g/L] — — R²: 0.15158
Spearman's ρ: 0.292		 Age, sex, PCs(1-40) —
PPM001489 PGS000691
(snpnet.Non_albumin_protein)
 PSS000731 PGP000128 Sinnott-Armstrong N et al. (2021) Reported Trait: Non-albumin protein [g/L] — — R²: 0.12839
Spearman's ρ: 0.31		 Age, sex, PCs(1-40) —
PPM001454 PGS000691
(snpnet.Non_albumin_protein)
 PSS000730 PGP000128 Sinnott-Armstrong N et al. (2021) Reported Trait: Non-albumin protein [g/L] — — R²: 0.0886
Spearman's ρ: 0.216		 Age, sex, PCs(1-40) —
PPM001419 PGS000691
(snpnet.Non_albumin_protein)
 PSS000729 PGP000128 Sinnott-Armstrong N et al. (2021) Reported Trait: Non-albumin protein [g/L] — — R²: 0.07146
Spearman's ρ: 0.16		 Age, sex, PCs(1-40) —

Evaluated Samples

PGS Sample Set ID
(PSS ID) 		Phenotype Definitions and Methods Participant Follow-up Time Sample Numbers Age of Study Participants Sample Ancestry Additional Ancestry Description Cohort(s) Additional Sample/Cohort Information
PSS000729 — — 5,573 individuals — African unspecified — UKB —
PSS000730 — — 984 individuals — East Asian — UKB —
PSS000731 — — 21,516 individuals — European Non-British White UKB —
PSS000732 — — 6,687 individuals — South Asian — UKB —
PSS000733 — — 58,196 individuals — European
(British)		 — UKB —