Trait: self-reported trait

Experimental Factor Ontology (EFO) Information
Identifier EFO_0009799
Description
  • Characteristics of an individual that are reported by the individual, usually to medical staff, including via questionnaires, rather than observed or measured directly by medical staff.
Trait category
Other trait
Child trait(s) 3 child traits

Associated Polygenic Score(s)

Note: This table shows all PGS for "self-reported trait" and any child terms of this trait in the EFO hierarchy by default.
Polygenic Score (PGS) ID PGS Name PGS Publication (PGP) ID Reported Trait Mapped Trait(s) (Ontology) Number of Variants PGS Scoring File (FTP Link)
PGS000140 GPpsy PGP000068 Cai N et al. Nat Genet (2020) Broad Depression (seen a General Practitioner for nerves, anxiety, tension or depression) seeing a general practitioner for nerves, anxiety, tension or depression, self-reported
depressive disorder
24,665 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000140/ScoringFiles/PGS000140.txt.gz
PGS000141 Psypsy PGP000068 Cai N et al. Nat Genet (2020) Seen a psychiatrist for nerves, anxiety, tension or depression seeing a psychiatrist for nerves, anxiety, tension or depression, self-reported
depressive disorder
22,728 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000141/ScoringFiles/PGS000141.txt.gz
PGS000142 DepAll PGP000068 Cai N et al. Nat Genet (2020) Probable Depression (low mood or anhedonia, and seen a GP or psychiatrist for nerves, anxiety, tension or depression) seeing a general practitioner for nerves, anxiety, tension or depression, self-reported
seeing a psychiatrist for nerves, anxiety, tension or depression, self-reported
depressive disorder
21,908 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000142/ScoringFiles/PGS000142.txt.gz
PGS000143 GPNoDep PGP000068 Cai N et al. Nat Genet (2020) Seen a General Practitioner for nerves, anxiety, tension or depression (without report of low mood or anhedonia) seeing a general practitioner for nerves, anxiety, tension or depression, self-reported 21,042 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000143/ScoringFiles/PGS000143.txt.gz
PGS000144 SelfRepDep PGP000068 Cai N et al. Nat Genet (2020) Self-reported depression or depression symptoms self-reported trait
depressive symptom measurement
21,828 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000144/ScoringFiles/PGS000144.txt.gz
PGS000716 PGS295_elbs PGP000132 Richardson TG et al. BMJ (2020) Early life body size comparative body size at age 10, self-reported
body mass index
295 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000716/ScoringFiles/PGS000716.txt.gz

PGS Performance Metrics

Disclaimer: The performance metrics are displayed as reported by the source studies. It is important to note that metrics are not necessarily comparable with each other. For example, metrics depend on the sample characteristics (described by the PGS Catalog Sample Set [PSS] ID), phenotyping, and statistical modelling. Please refer to the source publication for additional guidance on performance.

PGS Performance Metric ID
(PPM ID)
Evaluated Score PGS Sample Set ID
(PSS ID)
Performance Source Trait PGS Effect Sizes
(per SD change)
PGS Classification Metrics Other Metrics Covariates Included in the Model PGS Performance: Other Relevant Information
PPM001708 PGS000716
(PGS295_elbs)
PSS000883 PGP000140 Brandkvist M et al. (2020) Ext. Reported Trait: Obesity in individuals aged 30-69.9 AUROC: 0.569 [0.564, 0.574] Due to a lack of information in the HUNT dataset, only 277 of the 295 common variants used to build the childhood score by Richardson et al were included.
PPM001709 PGS000716
(PGS295_elbs)
PSS000876 PGP000140 Brandkvist M et al. (2020) Ext. Reported Trait: Overweight in individuals aged 12-15.9 AUROC: 0.656 [0.626, 0.686] Due to a lack of information in the HUNT dataset, only 277 of the 295 common variants used to build the childhood score by Richardson et al were included.
PPM001710 PGS000716
(PGS295_elbs)
PSS000878 PGP000140 Brandkvist M et al. (2020) Ext. Reported Trait: Overweight in individuals aged 16-17.9 AUROC: 0.623 [0.589, 0.657] Due to a lack of information in the HUNT dataset, only 277 of the 295 common variants used to build the childhood score by Richardson et al were included.
PPM001711 PGS000716
(PGS295_elbs)
PSS000880 PGP000140 Brandkvist M et al. (2020) Ext. Reported Trait: Overweight in individuals aged 18-23.9 AUROC: 0.601 [0.589, 0.612] Due to a lack of information in the HUNT dataset, only 277 of the 295 common variants used to build the childhood score by Richardson et al were included.
PPM001712 PGS000716
(PGS295_elbs)
PSS000882 PGP000140 Brandkvist M et al. (2020) Ext. Reported Trait: Overweight in individuals aged 14-29.9 AUROC: 0.591 [0.582, 0.6] Due to a lack of information in the HUNT dataset, only 277 of the 295 common variants used to build the childhood score by Richardson et al were included.
PPM001713 PGS000716
(PGS295_elbs)
PSS000884 PGP000140 Brandkvist M et al. (2020) Ext. Reported Trait: Overweight in individuals aged 30-69.9 AUROC: 0.568 [0.563, 0.573] Due to a lack of information in the HUNT dataset, only 277 of the 295 common variants used to build the childhood score by Richardson et al were included.
PPM000435 PGS000143
(GPNoDep)
PSS000250 PGP000068 Cai N et al. (2020) Reported Trait: Major Depressive Disorder status AUROC: 0.53441 : 0.00471 Cohort
PPM001707 PGS000716
(PGS295_elbs)
PSS000879 PGP000140 Brandkvist M et al. (2020) Ext. Reported Trait: Obesity in individuals aged 18-23.9 AUROC: 0.618 [0.594, 0.641] Due to a lack of information in the HUNT dataset, only 277 of the 295 common variants used to build the childhood score by Richardson et al were included.
PPM000433 PGS000141
(Psypsy)
PSS000250 PGP000068 Cai N et al. (2020) Reported Trait: Major Depressive Disorder status AUROC: 0.52988 : 0.00438 Cohort
PPM000436 PGS000144
(SelfRepDep)
PSS000250 PGP000068 Cai N et al. (2020) Reported Trait: Major Depressive Disorder status AUROC: 0.51641 : 0.00117 Cohort
PPM000434 PGS000142
(DepAll)
PSS000250 PGP000068 Cai N et al. (2020) Reported Trait: Major Depressive Disorder status AUROC: 0.5333 : 0.00492 Cohort
PPM000432 PGS000140
(GPpsy)
PSS000250 PGP000068 Cai N et al. (2020) Reported Trait: Major Depressive Disorder status AUROC: 0.53193 : 0.00481 Cohort
PPM001687 PGS000716
(PGS295_elbs)
PSS000879 PGP000140 Brandkvist M et al. (2020) Ext. Reported Trait: Obesity in individuals aged 18-23.9 AUROC: 0.619 [0.596, 0.643] Due to a lack of information in the HUNT dataset, only 289 of the 295 common variants used to build the childhood score by Richardson et al were included. Additionally, 11 of the 289 common variants were proxies. Proxy SNPs were accepted if they had an R^2 ≥0.8 as well as a D’ ≥0.95 using publicly available reference haplotypes of a European British in England and Scotland population from Phase 3 (Version 5) of the 1000 Genomes Project.
PPM001688 PGS000716
(PGS295_elbs)
PSS000881 PGP000140 Brandkvist M et al. (2020) Ext. Reported Trait: Obesity in individuals aged 24-29.9 AUROC: 0.602 [0.585, 0.618] Due to a lack of information in the HUNT dataset, only 289 of the 295 common variants used to build the childhood score by Richardson et al were included. Additionally, 11 of the 289 common variants were proxies. Proxy SNPs were accepted if they had an R^2 ≥0.8 as well as a D’ ≥0.95 using publicly available reference haplotypes of a European British in England and Scotland population from Phase 3 (Version 5) of the 1000 Genomes Project.
PPM001689 PGS000716
(PGS295_elbs)
PSS000883 PGP000140 Brandkvist M et al. (2020) Ext. Reported Trait: Obesity in individuals aged 30-69.9 AUROC: 0.569 [0.564, 0.574] Due to a lack of information in the HUNT dataset, only 289 of the 295 common variants used to build the childhood score by Richardson et al were included. Additionally, 11 of the 289 common variants were proxies. Proxy SNPs were accepted if they had an R^2 ≥0.8 as well as a D’ ≥0.95 using publicly available reference haplotypes of a European British in England and Scotland population from Phase 3 (Version 5) of the 1000 Genomes Project.
PPM001690 PGS000716
(PGS295_elbs)
PSS000876 PGP000140 Brandkvist M et al. (2020) Ext. Reported Trait: Overweight in individuals aged 12-15.9 AUROC: 0.658 [0.628, 0.687] Due to a lack of information in the HUNT dataset, only 289 of the 295 common variants used to build the childhood score by Richardson et al were included. Additionally, 11 of the 289 common variants were proxies. Proxy SNPs were accepted if they had an R^2 ≥0.8 as well as a D’ ≥0.95 using publicly available reference haplotypes of a European British in England and Scotland population from Phase 3 (Version 5) of the 1000 Genomes Project.
PPM001691 PGS000716
(PGS295_elbs)
PSS000878 PGP000140 Brandkvist M et al. (2020) Ext. Reported Trait: Overweight in individuals aged 16-17.9 AUROC: 0.624 [0.589, 0.658] Due to a lack of information in the HUNT dataset, only 289 of the 295 common variants used to build the childhood score by Richardson et al were included. Additionally, 11 of the 289 common variants were proxies. Proxy SNPs were accepted if they had an R^2 ≥0.8 as well as a D’ ≥0.95 using publicly available reference haplotypes of a European British in England and Scotland population from Phase 3 (Version 5) of the 1000 Genomes Project.
PPM001692 PGS000716
(PGS295_elbs)
PSS000880 PGP000140 Brandkvist M et al. (2020) Ext. Reported Trait: Overweight in individuals aged 18-23.9 AUROC: 0.602 [0.59, 0.613] Due to a lack of information in the HUNT dataset, only 289 of the 295 common variants used to build the childhood score by Richardson et al were included. Additionally, 11 of the 289 common variants were proxies. Proxy SNPs were accepted if they had an R^2 ≥0.8 as well as a D’ ≥0.95 using publicly available reference haplotypes of a European British in England and Scotland population from Phase 3 (Version 5) of the 1000 Genomes Project.
PPM001693 PGS000716
(PGS295_elbs)
PSS000882 PGP000140 Brandkvist M et al. (2020) Ext. Reported Trait: Overweight in individuals aged 14-29.9 AUROC: 0.591 [0.582, 0.6] Due to a lack of information in the HUNT dataset, only 289 of the 295 common variants used to build the childhood score by Richardson et al were included. Additionally, 11 of the 289 common variants were proxies. Proxy SNPs were accepted if they had an R^2 ≥0.8 as well as a D’ ≥0.95 using publicly available reference haplotypes of a European British in England and Scotland population from Phase 3 (Version 5) of the 1000 Genomes Project.
PPM001633 PGS000716
(PGS295_elbs)
PSS000849 PGP000132 Richardson TG et al. (2020) Reported Trait: Childhood body mass index AUROC: 0.64
PPM001635 PGS000716
(PGS295_elbs)
PSS000847 PGP000132 Richardson TG et al. (2020) Reported Trait: Adolescent body mass index AUROC: 0.63
PPM001637 PGS000716
(PGS295_elbs)
PSS000848 PGP000132 Richardson TG et al. (2020) Reported Trait: Adult body mass index AUROC: 0.57
PPM001705 PGS000716
(PGS295_elbs)
PSS000875 PGP000140 Brandkvist M et al. (2020) Ext. Reported Trait: Obesity in individuals aged 12-15.9 AUROC: 0.739 [0.667, 0.811] Due to a lack of information in the HUNT dataset, only 277 of the 295 common variants used to build the childhood score by Richardson et al were included.
PPM001706 PGS000716
(PGS295_elbs)
PSS000877 PGP000140 Brandkvist M et al. (2020) Ext. Reported Trait: Obesity in individuals aged 16-17.9 AUROC: 0.66 [0.566, 0.754] Due to a lack of information in the HUNT dataset, only 277 of the 295 common variants used to build the childhood score by Richardson et al were included.
PPM001685 PGS000716
(PGS295_elbs)
PSS000875 PGP000140 Brandkvist M et al. (2020) Ext. Reported Trait: Obesity in individuals aged 12-15.9 AUROC: 0.735 [0.663, 0.806] Due to a lack of information in the HUNT dataset, only 289 of the 295 common variants used to build the childhood score by Richardson et al were included. Additionally, 11 of the 289 common variants were proxies. Proxy SNPs were accepted if they had an R^2 ≥0.8 as well as a D’ ≥0.95 using publicly available reference haplotypes of a European British in England and Scotland population from Phase 3 (Version 5) of the 1000 Genomes Project.
PPM001686 PGS000716
(PGS295_elbs)
PSS000877 PGP000140 Brandkvist M et al. (2020) Ext. Reported Trait: Obesity in individuals aged 16-17.9 AUROC: 0.672 [0.577, 0.766] Due to a lack of information in the HUNT dataset, only 289 of the 295 common variants used to build the childhood score by Richardson et al were included. Additionally, 11 of the 289 common variants were proxies. Proxy SNPs were accepted if they had an R^2 ≥0.8 as well as a D’ ≥0.95 using publicly available reference haplotypes of a European British in England and Scotland population from Phase 3 (Version 5) of the 1000 Genomes Project.
PPM001694 PGS000716
(PGS295_elbs)
PSS000884 PGP000140 Brandkvist M et al. (2020) Ext. Reported Trait: Overweight in individuals aged 30-69.9 AUROC: 0.568 [0.563, 0.573] Due to a lack of information in the HUNT dataset, only 289 of the 295 common variants used to build the childhood score by Richardson et al were included. Additionally, 11 of the 289 common variants were proxies. Proxy SNPs were accepted if they had an R^2 ≥0.8 as well as a D’ ≥0.95 using publicly available reference haplotypes of a European British in England and Scotland population from Phase 3 (Version 5) of the 1000 Genomes Project.

Evaluated Samples

PGS Sample Set ID
(PSS ID)
Phenotype Definitions and Methods Participant Follow-up Time Sample Numbers Age of Study Participants Sample Ancestry Additional Ancestry Description Cohort(s) Additional Sample/Cohort Information
PSS000847 Measurs of BMI were dichotomised to classify individuals higher than th 85th centiles as overweight. 3,997 individuals Mean = 17.8 years European ALSPAC ALSPAC offspring
PSS000848 Measurs of BMI were dichotomised to classify individuals higher than th 85th centiles as overweight. 2,199 individuals,
0.0 % Male samples
Mean = 50.8 years European ALSPAC ALSPAC mothers
PSS000849 Measurs of BMI were dichotomised to classify individuals higher than th 85th centiles as overweight. 5,898 individuals Mean = 9.9 years European ALSPAC ALSPAC offspring
PSS000876 BMI was calculated as weight in kilograms per height in metres squared. Weight was measured to the nearest half kilogram wih participants wearing light cloes and no shoes and height was measured to the nearest centimeter. WHO defines overweight as BMI greater than or equal to 25 and obesity as BMI greater than or equal to 30. BMI strongly related to longitudinal growth. To defiine corresponding cut-offs for obesity and overweight for participants younger than 18 years, BMI z score was calulated using age and sex specific reference from the International Obesity Task Force.
[
  • 344 cases
  • , 2,780 controls
]
European HUNT
PSS000875 BMI was calculated as weight in kilograms per height in metres squared. Weight was measured to the nearest half kilogram wih participants wearing light cloes and no shoes and height was measured to the nearest centimeter. WHO defines overweight as BMI greater than or equal to 25 and obesity as BMI greater than or equal to 30. BMI strongly related to longitudinal growth. To defiine corresponding cut-offs for obesity and overweight for participants younger than 18 years, BMI z score was calulated using age and sex specific reference from the International Obesity Task Force.
[
  • 37 cases
  • , 3,087 controls
]
European HUNT
PSS000878 BMI was calculated as weight in kilograms per height in metres squared. Weight was measured to the nearest half kilogram wih participants wearing light cloes and no shoes and height was measured to the nearest centimeter. WHO defines overweight as BMI greater than or equal to 25 and obesity as BMI greater than or equal to 30. BMI strongly related to longitudinal growth. To defiine corresponding cut-offs for obesity and overweight for participants younger than 18 years, BMI z score was calulated using age and sex specific reference from the International Obesity Task Force.
[
  • 274 cases
  • , 2,622 controls
]
European HUNT
PSS000879 BMI was calculated as weight in kilograms per height in metres squared. Weight was measured to the nearest half kilogram wih participants wearing light cloes and no shoes and height was measured to the nearest centimeter. WHO defines overweight as BMI greater than or equal to 25 and obesity as BMI greater than or equal to 30. BMI strongly related to longitudinal growth.
[
  • 542 cases
  • , 11,637 controls
]
European HUNT
PSS000880 BMI was calculated as weight in kilograms per height in metres squared. Weight was measured to the nearest half kilogram wih participants wearing light cloes and no shoes and height was measured to the nearest centimeter. WHO defines overweight as BMI greater than or equal to 25 and obesity as BMI greater than or equal to 30. BMI strongly related to longitudinal growth.
[
  • 2,898 cases
  • , 9,281 controls
]
European HUNT
PSS000881 BMI was calculated as weight in kilograms per height in metres squared. Weight was measured to the nearest half kilogram wih participants wearing light cloes and no shoes and height was measured to the nearest centimeter. WHO defines overweight as BMI greater than or equal to 25 and obesity as BMI greater than or equal to 30. BMI strongly related to longitudinal growth.
[
  • 1,240 cases
  • , 15,899 controls
]
European HUNT
PSS000882 BMI was calculated as weight in kilograms per height in metres squared. Weight was measured to the nearest half kilogram wih participants wearing light cloes and no shoes and height was measured to the nearest centimeter. WHO defines overweight as BMI greater than or equal to 25 and obesity as BMI greater than or equal to 30. BMI strongly related to longitudinal growth.
[
  • 5,775 cases
  • , 11,364 controls
]
European HUNT
PSS000883 BMI was calculated as weight in kilograms per height in metres squared. Weight was measured to the nearest half kilogram wih participants wearing light cloes and no shoes and height was measured to the nearest centimeter. WHO defines overweight as BMI greater than or equal to 25 and obesity as BMI greater than or equal to 30. BMI strongly related to longitudinal growth.
[
  • 15,112 cases
  • , 47,429 controls
]
European HUNT
PSS000884 BMI was calculated as weight in kilograms per height in metres squared. Weight was measured to the nearest half kilogram wih participants wearing light cloes and no shoes and height was measured to the nearest centimeter. WHO defines overweight as BMI greater than or equal to 25 and obesity as BMI greater than or equal to 30. BMI strongly related to longitudinal growth.
[
  • 43,408 cases
  • , 19,133 controls
]
European HUNT
PSS000877 BMI was calculated as weight in kilograms per height in metres squared. Weight was measured to the nearest half kilogram wih participants wearing light cloes and no shoes and height was measured to the nearest centimeter. WHO defines overweight as BMI greater than or equal to 25 and obesity as BMI greater than or equal to 30. BMI strongly related to longitudinal growth. To defiine corresponding cut-offs for obesity and overweight for participants younger than 18 years, BMI z score was calulated using age and sex specific reference from the International Obesity Task Force.
[
  • 30 cases
  • , 2,866 controls
]
European HUNT
PSS000250
[
  • 14,696 cases
  • , 22,013 controls
]
European 15 cohorts
  • BOMA
  • ,CoLaus
  • ,Edinburgh
  • ,GenPOD
  • ,GenRED
  • ,MARS
  • ,MPIP
  • ,NESDA
  • ,QIMR
  • ,RADIANT
  • ,RS
  • ,SHIP
  • ,STAR*D
  • ,TwinGene
  • ,i2b2
Part of PGC29 (PMID: 29700475)