| Experimental Factor Ontology (EFO) Information | |
| Identifier | EFO_0010246 |
| Description |
|
Trait category |
Other trait
|
| Polygenic Score (PGS) ID | PGS Name | PGS Publication (PGP) ID | Reported Trait | Number of Variants | PGS Scoring File (FTP Link) |
|---|---|---|---|---|---|
| PGS000139 | MDDRecur | PGP000068 Cai N et al. Nat Genet (2020) |
Lifetime Major Depressive Disorder (with recurrence) | 21,980 | http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000139/ScoringFiles/PGS000139.txt.gz |
Disclaimer: The performance metrics are displayed as reported by the source studies. It is important to note that metrics are not necessarily comparable with each other. For example, metrics depend on the sample characteristics (described by the PGS Catalog Sample Set [PSS] ID), phenotyping, and statistical modelling. Please refer to the source publication for additional guidance on performance.
|
PGS Performance Metric ID (PPM ID) |
Evaluated Score |
PGS Sample Set ID (PSS ID) |
Performance Source | Trait |
PGS Effect Sizes (per SD change) |
PGS Classification Metrics | Other Metrics | Covariates Included in the Model | PGS Performance: Other Relevant Information |
|---|---|---|---|---|---|---|---|---|---|
| PPM000431 | PGS000139 (MDDRecur) | PSS000250 | PGP000068 Cai N et al. (2020) |
Reported Trait: Major Depressive Disorder status | — | AUROC: 0.5487412 | R²: 0.01097163 | Cohort | — |
|
PGS Sample Set ID (PSS ID) |
Detailed Phenotype Description | Participant Follow-up Time | Sample Numbers | Age of Study Participants | Sample Ancestry | Additional Ancestry Description | Cohort(s) | Additional Sample/Cohort Information |
|---|---|---|---|---|---|---|---|---|
| PSS000250 | — | — | [
|
— | European | — | 15 cohorts
|
Part of PGC29 (PMID: 29700475) |