Experimental Factor Ontology (EFO) Information | |
Identifier | EFO_1000802 |
Description | FIBROSIS of the hepatic parenchyma due to chronic excess ALCOHOL DRINKING. | Trait category |
Cancer
Digestive system disorder
|
Synonyms |
15 synonyms
|
Mapped term(s) |
15 mapped terms
|
Polygenic Score (PGS) ID | PGS Name | PGS Publication (PGP) ID | Reported Trait | Mapped Trait(s) (Ontology) | Number of Variants | PGS Scoring File (FTP Link) |
---|---|---|---|---|---|---|
PGS000704 | HC171 | PGP000128 Sinnott-Armstrong N et al. Nat Genet (2021) | Alcoholic cirrhosis | alcoholic liver cirrhosis | 183,271 | http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000704/ScoringFiles/PGS000704.txt.gz |
PGS Performance Metric ID (PPM ID) |
Evaluated Score |
PGS Sample Set ID (PSS ID) |
Performance Source | Trait |
PGS Effect Sizes (per SD change) |
PGS Classification Metrics | Other Metrics | Covariates Included in the Model | PGS Performance: Other Relevant Information |
---|---|---|---|---|---|---|---|---|---|
PPM001596 | PGS000704 (HC171) |
PSS000792 | PGP000128 Sinnott-Armstrong N et al. (2021) | Reported Trait: Alcoholic cirrhosis | — | AUROC: 0.55471 | — | Age, sex, PCs(1-10) | — |
PPM001607 | PGS000704 (HC171) |
PSS000793 | PGP000128 Sinnott-Armstrong N et al. (2021) | Reported Trait: Alcoholic cirrhosis | HR: 1.18 [1.11, 1.27] | C-index: 0.711 | — | Age as time scale, sex, batch, PCs(1-10) | — |
PGS Sample Set ID (PSS ID) |
Phenotype Definitions and Methods | Participant Follow-up Time | Sample Numbers | Age of Study Participants | Sample Ancestry | Additional Ancestry Description | Cohort(s) | Additional Sample/Cohort Information |
---|---|---|---|---|---|---|---|---|
PSS000792 | — | — | 87,413 individuals | — | European | — | UKB | — |
PSS000793 | ICD-10 K70 | — | [
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— | European (Finnish) |
— | FinnGen | — |