Trait: Cholecystitis

Trait Information
Identifier HP_0001082
Description The presence of inflammatory changes in the gallbladder. [HPO: probinson]
Trait category
Other trait
Synonyms Gallbladder inflammation
Mapped term(s) 4 mapped terms
  • ICD10:K81
  • MSH:D002764
  • SNOMEDCT_US:76581006
  • UMLS:C0008325

Associated Polygenic Score(s)

Polygenic Score (PGS) ID PGS Name PGS Publication (PGP) ID Reported Trait Mapped Trait(s) (Ontology) Number of Variants PGS Scoring File (FTP Link)
PGS000707 HC225 PGP000128 Sinnott-Armstrong N et al. Nat Genet (2021) Cholecystitis Cholecystitis 183,329 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000707/ScoringFiles/PGS000707.txt.gz - Check Terms/Licenses

PGS Performance Metrics

Disclaimer: The performance metrics are displayed as reported by the source studies. It is important to note that metrics are not necessarily comparable with each other. For example, metrics depend on the sample characteristics (described by the PGS Catalog Sample Set [PSS] ID), phenotyping, and statistical modelling. Please refer to the source publication for additional guidance on performance.

PGS Performance Metric ID
(PPM ID)
Evaluated Score PGS Sample Set ID
(PSS ID)
Performance Source Trait PGS Effect Sizes
(per SD change)
PGS Classification Metrics Other Metrics Covariates Included in the Model PGS Performance: Other Relevant Information
PPM001599 PGS000707
(HC225)
PSS000799 PGP000128 Sinnott-Armstrong N et al. (2021) Reported Trait: Cholecystitis AUROC: 0.6038 Age, sex, PCs(1-10)

Evaluated Samples

PGS Sample Set ID
(PSS ID)
Phenotype Definitions and Methods Participant Follow-up Time Sample Numbers Age of Study Participants Sample Ancestry Additional Ancestry Description Cohort(s) Additional Sample/Cohort Information
PSS000799 87,413 individuals European UKB