Polygenic Scores

Polygenic Score (PGS) ID PGS Name Publication ID Reported Trait Mapped Trait(s) (EFO) Number of Variants PGS Download Links
PGS000001 PRS77_BC Mavaddat N et al. J Natl Cancer Inst (2015) Breast Cancer breast carcinoma 77 FTP Link
PGS000002 PRS77_ERpos Mavaddat N et al. J Natl Cancer Inst (2015) ER-positive Breast Cancer estrogen-receptor positive breast cancer 77 FTP Link
PGS000003 PRS77_ERneg Mavaddat N et al. J Natl Cancer Inst (2015) ER-negative Breast Cancer estrogen-receptor negative breast cancer 77 FTP Link
PGS000004 PRS313_BC Mavaddat N et al. Am J Hum Genet (2018) Breast Cancer breast carcinoma 313 FTP Link
PGS000005 PRS313_ERpos Mavaddat N et al. Am J Hum Genet (2018) ER-positive Breast Cancer estrogen-receptor positive breast cancer 313 FTP Link
PGS000006 PRS313_ERneg Mavaddat N et al. Am J Hum Genet (2018) ER-negative Breast Cancer estrogen-receptor negative breast cancer 313 FTP Link
PGS000007 PRS3820_BC Mavaddat N et al. Am J Hum Genet (2018) Breast Cancer breast carcinoma 3,820 FTP Link
PGS000008 PRS3820_ERpos Mavaddat N et al. Am J Hum Genet (2018) ER-positive Breast Cancer estrogen-receptor positive breast cancer 3,820 FTP Link
PGS000009 PRS3820_ERneg Mavaddat N et al. Am J Hum Genet (2018) ER-negative Breast Cancer estrogen-receptor negative breast cancer 3,820 FTP Link
PGS000010 GRS27 Mega JL et al. Lancet (2015) Coronary heart disease coronary heart disease 27 FTP Link
PGS000011 GRS50 Tada H et al. Eur Heart J (2015) Coronary artery disease coronary artery disease 50 FTP Link
PGS000012 GRS49K Abraham G et al. Eur Heart J (2016) Coronary artery disease coronary artery disease 49,310 FTP Link
PGS000013 GPS_CAD Khera AV et al. Nat Genet (2018) Coronary artery disease coronary artery disease 6,630,150 FTP Link
PGS000014 GPS_T2D Khera AV et al. Nat Genet (2018) Type 2 diabetes type II diabetes mellitus 6,917,436 FTP Link
PGS000015 GPS_BC Khera AV et al. Nat Genet (2018) Breast cancer breast carcinoma 5,218 FTP Link
PGS000016 GPS_AF Khera AV et al. Nat Genet (2018) Atrial fibrillation atrial fibrillation 6,730,541 FTP Link
PGS000017 GPS_IBD Khera AV et al. Nat Genet (2018) Inflammatory bowel disease inflammatory bowel disease 6,907,112 FTP Link
PGS000018 metaGRS_CAD Inouye M et al. J Am Coll Cardiol (2018) Coronary artery disease coronary artery disease 1,745,180 FTP Link
PGS000019 GRS_CAD Paquette M et al. J Clin Lipidol (2017) Coronary artery disease coronary artery disease 192 FTP Link
PGS000020 dGRS1000 Läll K et al. Genet Med (2016) Type 2 diabetes type II diabetes mellitus 7,502 FTP Link
PGS000021 GRS1 Oram RA et al. Diabetes Care (2015) Type 1 diabetes type I diabetes mellitus 30 FTP Link
PGS000022 T1D_GRS Perry DJ et al. Sci Rep (2018) Type 1 diabetes type I diabetes mellitus 37 FTP Link
PGS000023 AA_GRS Onengut-Gumuscu S et al. Diabetes Care (2019) Type 1 diabetes type I diabetes mellitus 7 FTP Link
PGS000024 GRS2 Sharp SA et al. Diabetes Care (2019) Type 1 diabetes type I diabetes mellitus 67 FTP Link
PGS000025 GRS Chouraki V et al. J Alzheimers Dis (2016) Alzheimer's Disease Alzheimer's disease 19 FTP Link
PGS000026 PHS Desikan RS et al. PLoS Med (2017) Alzheimer’s Disease Alzheimer's disease 31 FTP Link
PGS000027 GPS_BMI Khera AV et al. Cell (2019) Body Mass Index body mass index 2,100,302 FTP Link
PGS000028 PRS Shieh Y et al. Breast Cancer Res Treat (2016) Breast cancer breast carcinoma 83 FTP Link
PGS000029 PRS_AS Shieh Y et al. Breast Cancer Res Treat (2016) Breast cancer breast carcinoma 76 FTP Link
PGS000030 PrCa Schumacher FR et al. Nat Genet (2018) Prostate cancer prostate carcinoma 147 FTP Link
PGS000031 GRSt Vassy JL et al. Diabetes (2014) Type 2 diabetes type II diabetes mellitus 62 FTP Link
PGS000032 GRSB Vassy JL et al. Diabetes (2014) Type 2 diabetes (based on SNPs involved in β-cell function) type II diabetes mellitus 20 FTP Link
PGS000033 GRSIR Vassy JL et al. Diabetes (2014) Type 2 diabetes (based on SNPs involved in insulin resistance) type II diabetes mellitus 10 FTP Link
PGS000034 GRS_BMI Song M et al. Diabetes (2017) Adult Body Mass Index body mass index 97 FTP Link
PGS000035 PRS_AF Weng LC et al. Circulation (2017) Atrial fibrillation atrial fibrillation 1,168 FTP Link
PGS000036 gePS_T2D Mahajan A et al. Nat Genet (2018) Type 2 diabetes type II diabetes mellitus 171,249 FTP Link
PGS000037 PGS_AST Belsky DW et al. Lancet Respir Med (2013) Asthma asthma 15 FTP Link
PGS000038 PRS90 Rutten-Jacobs LC et al. BMJ (2018) Stroke stroke 90 FTP Link
PGS000039 metaGRS_ischaemicstroke Abraham G et al. bioRxiv (2019) Ischaemic stroke Ischemic stroke 3,225,583 FTP Link
PGS000040 GRS_CeD Abraham G et al. PLoS Genet (2014) Coeliac disease celiac disease 228 FTP Link
PGS000041 GRS-DQ2.5-CeD Abraham G et al. Genome Med (2015) Coeliac disease celiac disease 2,513 FTP Link
PGS000042 GRS-DQ2.5-CeD-imputed Abraham G et al. Genome Med (2015) Coeliac disease celiac disease 3,317 FTP Link
PGS000043 PRS_VTE Klarin D et al. Nat Genet (2019) Venous thromboembolism venous thromboembolism 297 FTP Link
PGS000044 PrCa66 Pashayan N et al. Br J Cancer (2015) Prostate cancer prostate carcinoma 66 FTP Link
PGS000045 BCPRS_Overall Kuchenbaecker KB et al. J Natl Cancer Inst (2017) Breast cancer breast carcinoma 88 FTP Link
PGS000046 BCPRS_ER+ Kuchenbaecker KB et al. J Natl Cancer Inst (2017) Estrogen receptor [ER]-positive breast cancer estrogen-receptor positive breast cancer 87 FTP Link
PGS000047 BCPRS_ER- Kuchenbaecker KB et al. J Natl Cancer Inst (2017) Estrogen receptor [ER]-negative breast cancer estrogen-receptor negative breast cancer 53 FTP Link
PGS000048 OCPRS_Overall Kuchenbaecker KB et al. J Natl Cancer Inst (2017) Ovarian cancer ovarian carcinoma 17 FTP Link
PGS000049 PRS103_PrCa Lecarpentier J et al. J Clin Oncol (2017) Prostate Cancer prostate carcinoma 103 FTP Link
PGS000050 PRS44 Wen W et al. Breast Cancer Res (2016) Breast cancer breast carcinoma 44 FTP Link
PGS000051 PRS67 Zhang X et al. PLoS Med (2018) Breast Cancer breast carcinoma 67 FTP Link
PGS000052 sPRS161 Lakeman IMM et al. J Med Genet (2019) Breast cancer breast carcinoma 161 FTP Link
PGS000053 ALZ21_NIA-LOAD Tosto G et al. Neurology (2017) Alzheimer's disease (late onset) late-onset Alzheimers disease 21 FTP Link
PGS000054 ALZ21_EFIGA Tosto G et al. Neurology (2017) Alzheimer's disease (late onset) late-onset Alzheimers disease 21 FTP Link
PGS000055 PRS_CRC Schmit SL et al. J Natl Cancer Inst (2019) Colorectal cancer colorectal cancer 76 FTP Link
PGS000056 PD_PRS Paul KC et al. JAMA Neurol (2018) Parkinson Disease Parkinson's disease 23 FTP Link
PGS000057 CHD57 Natarajan P et al. Circulation (2017) Coronary heart disease coronary heart disease 57 FTP Link
PGS000058 CAD_GRS_204 Morieri ML et al. Diabetes Care (2018) Coronary artery disease coronary artery disease 204 FTP Link
PGS000059 CHD46 Hajek C et al. Circ Genom Precis Med (2018) Coronary heart disease coronary heart disease 46 FTP Link