PGS Publication: PGP000361

Publication Information (EuropePMC)
Title Your height affects your health: genetic determinants and health-related outcomes in Taiwan.
PubMed ID 35831902(Europe PMC)
doi 10.1186/s12916-022-02450-w
Publication Date July 13, 2022
Journal BMC Med
Author(s) Chiou JS, Cheng CF, Liang WM, Chou CH, Wang CH, Lin WD, Chiu ML, Cheng WC, Lin CW, Lin TH, Liao CC, Huang SM, Tsai CH, Lin YJ, Tsai FJ.
Released in PGS Catalog: Sept. 8, 2022

Associated Polygenic Score(s)

Filter PGS by Participant Ancestry
Individuals included in:
G - Source of Variant Associations (GWAS)
D - Score Development/Training
E - PGS Evaluation
List of ancestries includes:
Display options:
Ancestry legend
Multi-ancestry (including European)
Multi-ancestry (excluding European)
African
East Asian
South Asian
Additional Asian Ancestries
European
Greater Middle Eastern
Hispanic or Latin American
Additional Diverse Ancestries
Not Reported

PGS Developed By This Publication

Polygenic Score ID & Name PGS Publication ID (PGP) Reported Trait Mapped Trait(s) (Ontology) Number of Variants Ancestry distribution
GWAS
Dev
Eval
 Scoring File (FTP Link)
PGS002748
(PRS_251)
 PGP000361 |
Chiou JS et al. BMC Med (2022)
 Height body height 251
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002748/ScoringFiles/PGS002748.txt.gz

Performance Metrics

Disclaimer: The performance metrics are displayed as reported by the source studies. It is important to note that metrics are not necessarily comparable with each other. For example, metrics depend on the sample characteristics (described by the PGS Catalog Sample Set [PSS] ID), phenotyping, and statistical modelling. Please refer to the source publication for additional guidance on performance.

PGS Performance
Metric ID (PPM) 		Evaluated Score PGS Sample Set ID
(PSS) 		Performance Source Trait PGS Effect Sizes
(per SD change) 		Classification Metrics Other Metrics Covariates Included in the Model PGS Performance:
Other Relevant Information
PPM014929 PGS002748
(PRS_251)
 PSS009934|
East Asian Ancestry|
28,909 individuals
 PGP000361 |
Chiou JS et al. BMC Med (2022)
 Reported Trait: Height (male) β: 0.257 — — — —
PPM014930 PGS002748
(PRS_251)
 PSS009934|
East Asian Ancestry|
28,909 individuals
 PGP000361 |
Chiou JS et al. BMC Med (2022)
 Reported Trait: Height (female) β: 0.274 — — — —
PPM014931 PGS002748
(PRS_251)
 PSS009934|
East Asian Ancestry|
28,909 individuals
 PGP000361 |
Chiou JS et al. BMC Med (2022)
 Reported Trait: Body weight β: 1.218 [1.141, 1.296] — — — —
PPM014932 PGS002748
(PRS_251)
 PSS009934|
East Asian Ancestry|
28,909 individuals
 PGP000361 |
Chiou JS et al. BMC Med (2022)
 Reported Trait: Waist circumference β: 0.446 [0.375, 0.517] — — — —
PPM014933 PGS002748
(PRS_251)
 PSS009934|
East Asian Ancestry|
28,909 individuals
 PGP000361 |
Chiou JS et al. BMC Med (2022)
 Reported Trait: Hip circumference β: 0.601 [0.549, 0.652] — — — —
PPM014934 PGS002748
(PRS_251)
 PSS009934|
East Asian Ancestry|
28,909 individuals
 PGP000361 |
Chiou JS et al. BMC Med (2022)
 Reported Trait: Body mass index β: -0.084 [-0.111, -0.056] — — — —
PPM014935 PGS002748
(PRS_251)
 PSS009934|
East Asian Ancestry|
28,909 individuals
 PGP000361 |
Chiou JS et al. BMC Med (2022)
 Reported Trait: Waist‐hip ratio β: -0.001 [-0.001, 0.0] — — — —
PPM014936 PGS002748
(PRS_251)
 PSS009934|
East Asian Ancestry|
28,909 individuals
 PGP000361 |
Chiou JS et al. BMC Med (2022)
 Reported Trait: Body fat β: -0.14 [-0.186, -0.095] — — — —
PPM014937 PGS002748
(PRS_251)
 PSS009934|
East Asian Ancestry|
28,909 individuals
 PGP000361 |
Chiou JS et al. BMC Med (2022)
 Reported Trait: Total cholesterol β: -0.587 [-0.853, -0.321] — — — —
PPM014938 PGS002748
(PRS_251)
 PSS009934|
East Asian Ancestry|
28,909 individuals
 PGP000361 |
Chiou JS et al. BMC Med (2022)
 Reported Trait: Low‐density lipoprotein cholesterol β: -0.629 [-0.867, -0.391] — — — —

Evaluated Samples

PGS Sample Set ID
(PSS) 		Phenotype Definitions and Methods Participant Follow-up Time Sample Numbers Age of Study Participants Sample Ancestry Additional Ancestry Description Cohort(s) Additional Sample/Cohort Information
PSS009934 — — 28,909 individuals,
38.0 % Male samples
 — East Asian
(Han Chinese)		 — TWB —