Polygenic Score (PGS) ID: PGS019955

Predicted Trait
Reported Trait Acute rejection after kidney transplantation
Mapped Trait(s) renal transplant outcome measurement (EFO_0005199)
Released in PGS Catalog: Aug. 26, 2026
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Score Details

Score Construction
PGS Name PRS1308_AR
Development Method
Name clumping
Parameters r2 < 0.2, P-values 1×10−3
Variants
Original Genome Build NR
Number of Variants 1,308
Effect Weight Type beta
PGS Source
PGS Catalog Publication (PGP) ID PGP000845
Citation (link to publication) Cao R et al. PLoS One (2024)
Ancestry Distribution
Source of Variant
Associations (GWAS)
European: 100%
1,568 individuals (100%)
PGS Evaluation
European: 100%
1 Sample Sets

Development Samples

Source of Variant Associations (GWAS)
Study Identifiers Sample Numbers Sample Ancestry Cohort(s)
1,568 individuals,
53.0 % Male samples
European DeKAF Genomics

Performance Metrics

Disclaimer: The performance metrics are displayed as reported by the source studies. It is important to note that metrics are not necessarily comparable with each other. For example, metrics depend on the sample characteristics (described by the PGS Catalog Sample Set [PSS] ID), phenotyping, and statistical modelling. Please refer to the source publication for additional guidance on performance.

PGS Performance
Metric ID (PPM)
PGS Sample Set ID
(PSS)
Performance Source Trait PGS Effect Sizes
(per SD change)
Classification Metrics Other Metrics Covariates Included in the Model PGS Performance:
Other Relevant Information
PPM038150 PSS013842|
European Ancestry|
704 individuals
PGP000845 |
Cao R et al. PLoS One (2024)
Reported Trait: Acute rejection after kidney transplantation HR: 1.54 [1.07, 2.22]

Evaluated Samples

PGS Sample Set ID
(PSS)
Phenotype Definitions and Methods Participant Follow-up Time Sample Numbers Age of Study Participants Sample Ancestry Additional Ancestry Description Cohort(s) Additional Sample/Cohort Information
PSS013842 704 individuals,
53.0 % Male samples
European GEN-03