| Predicted Trait | |
| Reported Trait | Acute rejection after kidney transplantation |
| Mapped Trait(s) | renal transplant outcome measurement (EFO_0005199) |
| Score Construction | |
| PGS Name | PRS1308_AR |
| Development Method | |
| Name | clumping |
| Parameters | r2 < 0.2, P-values 1×10−3 |
| Variants | |
| Original Genome Build | NR |
| Number of Variants | 1,308 |
| Effect Weight Type | beta |
| PGS Source | |
| PGS Catalog Publication (PGP) ID | PGP000845 |
| Citation (link to publication) | Cao R et al. PLoS One (2024) |
| Ancestry Distribution | |
| Source of Variant Associations (GWAS) | European: 100% 1,568 individuals (100%) |
| PGS Evaluation | European: 100% 1 Sample Sets |
| Study Identifiers | Sample Numbers | Sample Ancestry | Cohort(s) |
|---|---|---|---|
| — | 1,568 individuals, 53.0 % Male samples |
European | DeKAF Genomics |
|
PGS Performance Metric ID (PPM) |
PGS Sample Set ID (PSS) |
Performance Source | Trait |
PGS Effect Sizes (per SD change) |
Classification Metrics | Other Metrics | Covariates Included in the Model |
PGS Performance: Other Relevant Information |
|---|---|---|---|---|---|---|---|---|
| PPM038150 | PSS013842| European Ancestry| 704 individuals |
PGP000845 | Cao R et al. PLoS One (2024) |
Reported Trait: Acute rejection after kidney transplantation | HR: 1.54 [1.07, 2.22] | — | — | — | — |
|
PGS Sample Set ID (PSS) |
Phenotype Definitions and Methods | Participant Follow-up Time | Sample Numbers | Age of Study Participants | Sample Ancestry | Additional Ancestry Description | Cohort(s) | Additional Sample/Cohort Information |
|---|---|---|---|---|---|---|---|---|
| PSS013842 | — | — | 704 individuals, 53.0 % Male samples |
— | European | — | GEN-03 | — |