Experimental Factor Ontology (EFO) Information | |
Identifier | EFO_0000612 |
Description | Gross necrosis of the myocardium, as a result of interruption of the blood supply to the area, as in coronary thrombosis. [NCIT: C27996] | Trait category |
Cardiovascular disease
|
Synonyms |
28 synonyms
|
Mapped term(s) |
13 mapped terms
|
Polygenic Score (PGS) ID | PGS Name | PGS Publication (PGP) ID | Reported Trait | Mapped Trait(s) (Ontology) | Number of Variants | PGS Scoring File (FTP Link) |
---|---|---|---|---|---|---|
PGS000710 | HC326 | PGP000128 Sinnott-Armstrong N et al. Nat Genet (2021) | Myocardial infarction | myocardial infarction | 183,566 | http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000710/ScoringFiles/PGS000710.txt.gz |
PGS Performance Metric ID (PPM ID) |
Evaluated Score |
PGS Sample Set ID (PSS ID) |
Performance Source | Trait |
PGS Effect Sizes (per SD change) |
PGS Classification Metrics | Other Metrics | Covariates Included in the Model | PGS Performance: Other Relevant Information |
---|---|---|---|---|---|---|---|---|---|
PPM001602 | PGS000710 (HC326) |
PSS000826 | PGP000128 Sinnott-Armstrong N et al. (2021) | Reported Trait: Myocardial infarction | — | AUROC: 0.59348 | — | Age, sex, PCs(1-10) | — |
PPM001606 | PGS000710 (HC326) |
PSS000827 | PGP000128 Sinnott-Armstrong N et al. (2021) | Reported Trait: Myocardial infarction | HR: 1.19 [1.17, 1.22] | C-index: 0.707 | — | Age as time scale, sex, batch, PCs(1-10) | — |
PGS Sample Set ID (PSS ID) |
Phenotype Definitions and Methods | Participant Follow-up Time | Sample Numbers | Age of Study Participants | Sample Ancestry | Additional Ancestry Description | Cohort(s) | Additional Sample/Cohort Information |
---|---|---|---|---|---|---|---|---|
PSS000826 | — | — | 87,413 individuals | — | European | — | UKB | — |
PSS000827 | ICD-10 I21|I22 | — | [
|
— | European (Finnish) |
— | FinnGen | — |