Trait: mean platelet volume

Experimental Factor Ontology (EFO) Information
Identifier EFO_0004584
Description A measurement of mean platelet volume is a machine-calculated measurement of the average size of platelets found in blood
Trait category
Hematological measurement
Mapped terms 2 mapped terms
  • MeSH:D063847
  • MedDRA:10050539

Associated Polygenic Score(s)

Filter PGS by Participant Ancestry
Individuals included in:
G - Source of Variant Associations (GWAS)
D - Score Development/Training
E - PGS Evaluation
List of ancestries includes:
Display options:
Ancestry legend
Multi-ancestry (including European)
Multi-ancestry (excluding European)
African
East Asian
South Asian
Additional Asian Ancestries
European
Greater Middle Eastern
Hispanic or Latin American
Additional Diverse Ancestries
Not Reported
Polygenic Score ID & Name PGS Publication ID (PGP) Reported Trait Mapped Trait(s) (Ontology) Number of Variants Ancestry distribution
GWAS
Dev
Eval
Scoring File (FTP Link)
PGS000104
(mpv)
PGP000051 |
Xu Y et al. Cell Genom (2022)
Mean platelet volume mean platelet volume 25,745
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000104/ScoringFiles/PGS000104.txt.gz
PGS000179
(mpv)
PGP000078 |
Vuckovic D et al. Cell (2020)
Mean platelet volume mean platelet volume 654
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000179/ScoringFiles/PGS000179.txt.gz
PGS001200
(GBE_INI30100)
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Mean platelet volume mean platelet volume 24,114
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001200/ScoringFiles/PGS001200.txt.gz
PGS001971
(portability-PLR_log_platelet_volume)
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Mean platelet (thrombocyte) volume mean platelet volume 65,450
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001971/ScoringFiles/PGS001971.txt.gz
PGS002189
(portability-ldpred2_log_platelet_volume)
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Mean platelet (thrombocyte) volume mean platelet volume 462,934
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002189/ScoringFiles/PGS002189.txt.gz
PGS002340
(blood_MEAN_PLATELET_VOL.BOLT-LMM)
PGP000332 |
Weissbrod O et al. Nat Genet (2022)
Mean platelet volume mean platelet volume 1,109,311
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002340/ScoringFiles/PGS002340.txt.gz
PGS002412
(blood_MEAN_PLATELET_VOL.P+T.0.0001)
PGP000332 |
Weissbrod O et al. Nat Genet (2022)
Mean platelet volume mean platelet volume 36,285
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002412/ScoringFiles/PGS002412.txt.gz
PGS002461
(blood_MEAN_PLATELET_VOL.P+T.0.001)
PGP000332 |
Weissbrod O et al. Nat Genet (2022)
Mean platelet volume mean platelet volume 65,237
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002461/ScoringFiles/PGS002461.txt.gz
PGS002510
(blood_MEAN_PLATELET_VOL.P+T.0.01)
PGP000332 |
Weissbrod O et al. Nat Genet (2022)
Mean platelet volume mean platelet volume 183,887
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002510/ScoringFiles/PGS002510.txt.gz
PGS002559
(blood_MEAN_PLATELET_VOL.P+T.1e-06)
PGP000332 |
Weissbrod O et al. Nat Genet (2022)
Mean platelet volume mean platelet volume 19,124
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002559/ScoringFiles/PGS002559.txt.gz
PGS002608
(blood_MEAN_PLATELET_VOL.P+T.5e-08)
PGP000332 |
Weissbrod O et al. Nat Genet (2022)
Mean platelet volume mean platelet volume 14,380
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002608/ScoringFiles/PGS002608.txt.gz
PGS002657
(blood_MEAN_PLATELET_VOL.PolyFun-pred)
PGP000332 |
Weissbrod O et al. Nat Genet (2022)
Mean platelet volume mean platelet volume 354,280
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002657/ScoringFiles/PGS002657.txt.gz
PGS002706
(blood_MEAN_PLATELET_VOL.SBayesR)
PGP000332 |
Weissbrod O et al. Nat Genet (2022)
Mean platelet volume mean platelet volume 973,986
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002706/ScoringFiles/PGS002706.txt.gz
PGS003548
(cont-decay-log_platelet_volume)
PGP000457 |
Ding Y et al. bioRxiv (2022)
|Pre
Mean platelet (thrombocyte) volume mean platelet volume 979,739
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003548/ScoringFiles/PGS003548.txt.gz
PGS003934
(INI30100)
PGP000502 |
Tanigawa Y et al. AJHG (2023)
Mean platelet (thrombocyte) volume mean platelet volume 31,032
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003934/ScoringFiles/PGS003934.txt.gz
PGS004354
(X30100.score)
PGP000561 |
Jung H et al. Commun Biol (2024)
Mean platelet (thrombocyte) volume mean platelet volume 1,059,939
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004354/ScoringFiles/PGS004354.txt.gz

Performance Metrics

Disclaimer: The performance metrics are displayed as reported by the source studies. It is important to note that metrics are not necessarily comparable with each other. For example, metrics depend on the sample characteristics (described by the PGS Catalog Sample Set [PSS] ID), phenotyping, and statistical modelling. Please refer to the source publication for additional guidance on performance.

PGS Performance
Metric ID (PPM)
Evaluated Score PGS Sample Set ID
(PSS)
Performance Source Trait PGS Effect Sizes
(per SD change)
Classification Metrics Other Metrics Covariates Included in the Model PGS Performance:
Other Relevant Information
PPM000240 PGS000104
(mpv)
PSS000169|
European Ancestry|
78,320 individuals
PGP000051 |
Xu Y et al. Cell Genom (2022)
Reported Trait: Mean platelet volume Pearson correlation coefficent (r): 0.61214 age, sex, 10 PCs of ancestry, lifestyle factors (diet, smoking, alcohol consumption), technical covariates (the time between venepuncture and full blood cell analysis, seasonal effects, centre of sample collection, time dependent drift of equipment, systematic differences in equipment) UKB Testing Set - these samples were held out from Score Development (regression training) but overlap with the samples used for variant selection (GWAS)
PPM000241 PGS000104
(mpv)
PSS000143|
European Ancestry|
37,224 individuals
PGP000051 |
Xu Y et al. Cell Genom (2022)
Reported Trait: Mean platelet volume Pearson correlation coefficent (r): 0.60875 age, sex, 10 PCs of ancestry, lifestyle factors (diet, smoking, alcohol consumption), technical covariates (the time between venepuncture and full blood cell analysis, seasonal effects, centre of sample collection, time dependent drift of equipment, systematic differences in equipment)
PPM000555 PGS000179
(mpv)
PSS000290|
European Ancestry|
2,314 individuals
PGP000078 |
Vuckovic D et al. Cell (2020)
Reported Trait: Mean platelet volume : 0.19379 sex, age, 10 genetic PCs
PPM000535 PGS000179
(mpv)
PSS000291|
European Ancestry|
39,260 individuals
PGP000078 |
Vuckovic D et al. Cell (2020)
Reported Trait: Mean platelet volume : 0.27306 sex, age, 10 genetic PCs
PPM001776 PGS000179
(mpv)
PSS000911|
Greater Middle Eastern Ancestry|
13,989 individuals
PGP000147 |
Thareja G et al. Nat Commun (2021)
|Ext.
Reported Trait: Mean platelet volume Pearson correlation coefficent (r): 0.51
PPM008619 PGS001200
(GBE_INI30100)
PSS006956|
African Ancestry|
6,139 individuals
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Reported Trait: Mean platelet volume : 0.11523 [0.10064, 0.12983]
Incremental R2 (full-covars): 0.10713
PGS R2 (no covariates): 0.10764 [0.09341, 0.12187]
age, sex, UKB array type, Genotype PCs
PPM008620 PGS001200
(GBE_INI30100)
PSS006957|
East Asian Ancestry|
1,655 individuals
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Reported Trait: Mean platelet volume : 0.22982 [0.19483, 0.26481]
Incremental R2 (full-covars): 0.1912
PGS R2 (no covariates): 0.20572 [0.17158, 0.23986]
age, sex, UKB array type, Genotype PCs
PPM008621 PGS001200
(GBE_INI30100)
PSS006958|
European Ancestry|
24,175 individuals
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Reported Trait: Mean platelet volume : 0.36048 [0.35094, 0.37001]
Incremental R2 (full-covars): 0.35332
PGS R2 (no covariates): 0.3577 [0.34816, 0.36724]
age, sex, UKB array type, Genotype PCs
PPM008622 PGS001200
(GBE_INI30100)
PSS006959|
South Asian Ancestry|
7,520 individuals
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Reported Trait: Mean platelet volume : 0.26489 [0.24813, 0.28164]
Incremental R2 (full-covars): 0.25606
PGS R2 (no covariates): 0.25974 [0.24303, 0.27644]
age, sex, UKB array type, Genotype PCs
PPM008623 PGS001200
(GBE_INI30100)
PSS006960|
European Ancestry|
65,636 individuals
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Reported Trait: Mean platelet volume : 0.36177 [0.35598, 0.36757]
Incremental R2 (full-covars): 0.35994
PGS R2 (no covariates): 0.36024 [0.35444, 0.36603]
age, sex, UKB array type, Genotype PCs
PPM010643 PGS001971
(portability-PLR_log_platelet_volume)
PSS009461|
European Ancestry|
19,423 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Mean platelet (thrombocyte) volume Partial Correlation (partial-r): 0.6032 [0.5942, 0.6121] sex, age, birth date, deprivation index, 16 PCs
PPM010644 PGS001971
(portability-PLR_log_platelet_volume)
PSS009235|
European Ancestry|
4,002 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Mean platelet (thrombocyte) volume Partial Correlation (partial-r): 0.6067 [0.5867, 0.626] sex, age, birth date, deprivation index, 16 PCs
PPM010645 PGS001971
(portability-PLR_log_platelet_volume)
PSS008789|
European Ancestry|
6,437 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Mean platelet (thrombocyte) volume Partial Correlation (partial-r): 0.5713 [0.5546, 0.5875] sex, age, birth date, deprivation index, 16 PCs
PPM010646 PGS001971
(portability-PLR_log_platelet_volume)
PSS008563|
Greater Middle Eastern Ancestry|
1,153 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Mean platelet (thrombocyte) volume Partial Correlation (partial-r): 0.5283 [0.485, 0.5691] sex, age, birth date, deprivation index, 16 PCs
PPM010647 PGS001971
(portability-PLR_log_platelet_volume)
PSS008341|
South Asian Ancestry|
6,078 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Mean platelet (thrombocyte) volume Partial Correlation (partial-r): 0.5282 [0.5098, 0.5461] sex, age, birth date, deprivation index, 16 PCs
PPM010648 PGS001971
(portability-PLR_log_platelet_volume)
PSS008118|
East Asian Ancestry|
1,762 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Mean platelet (thrombocyte) volume Partial Correlation (partial-r): 0.4452 [0.4067, 0.4821] sex, age, birth date, deprivation index, 16 PCs
PPM010649 PGS001971
(portability-PLR_log_platelet_volume)
PSS007905|
African Ancestry|
2,343 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Mean platelet (thrombocyte) volume Partial Correlation (partial-r): 0.3353 [0.2987, 0.3709] sex, age, birth date, deprivation index, 16 PCs
PPM010650 PGS001971
(portability-PLR_log_platelet_volume)
PSS009009|
African Ancestry|
3,711 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Mean platelet (thrombocyte) volume Partial Correlation (partial-r): 0.3125 [0.2831, 0.3414] sex, age, birth date, deprivation index, 16 PCs
PPM012359 PGS002189
(portability-ldpred2_log_platelet_volume)
PSS009461|
European Ancestry|
19,423 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Mean platelet (thrombocyte) volume Partial Correlation (partial-r): 0.5923 [0.5831, 0.6013] sex, age, birth date, deprivation index, 16 PCs
PPM012360 PGS002189
(portability-ldpred2_log_platelet_volume)
PSS009235|
European Ancestry|
4,002 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Mean platelet (thrombocyte) volume Partial Correlation (partial-r): 0.5914 [0.5709, 0.6113] sex, age, birth date, deprivation index, 16 PCs
PPM012361 PGS002189
(portability-ldpred2_log_platelet_volume)
PSS008789|
European Ancestry|
6,437 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Mean platelet (thrombocyte) volume Partial Correlation (partial-r): 0.5603 [0.5433, 0.5769] sex, age, birth date, deprivation index, 16 PCs
PPM012362 PGS002189
(portability-ldpred2_log_platelet_volume)
PSS008563|
Greater Middle Eastern Ancestry|
1,153 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Mean platelet (thrombocyte) volume Partial Correlation (partial-r): 0.5196 [0.4758, 0.5609] sex, age, birth date, deprivation index, 16 PCs
PPM012363 PGS002189
(portability-ldpred2_log_platelet_volume)
PSS008341|
South Asian Ancestry|
6,078 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Mean platelet (thrombocyte) volume Partial Correlation (partial-r): 0.5166 [0.4979, 0.5348] sex, age, birth date, deprivation index, 16 PCs
PPM012364 PGS002189
(portability-ldpred2_log_platelet_volume)
PSS008118|
East Asian Ancestry|
1,762 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Mean platelet (thrombocyte) volume Partial Correlation (partial-r): 0.444 [0.4054, 0.4809] sex, age, birth date, deprivation index, 16 PCs
PPM012365 PGS002189
(portability-ldpred2_log_platelet_volume)
PSS007905|
African Ancestry|
2,343 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Mean platelet (thrombocyte) volume Partial Correlation (partial-r): 0.3231 [0.2862, 0.3591] sex, age, birth date, deprivation index, 16 PCs
PPM012366 PGS002189
(portability-ldpred2_log_platelet_volume)
PSS009009|
African Ancestry|
3,711 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Mean platelet (thrombocyte) volume Partial Correlation (partial-r): 0.2907 [0.2609, 0.3199] sex, age, birth date, deprivation index, 16 PCs
PPM013105 PGS002340
(blood_MEAN_PLATELET_VOL.BOLT-LMM)
PSS009803|
African Ancestry|
6,153 individuals
PGP000332 |
Weissbrod O et al. Nat Genet (2022)
Reported Trait: Mean Platelet Volume Incremental R2 (full model vs. covariates alone): 0.1049 age, sex, age*sex, assessment center, genotyping array, 10 PCs
PPM013154 PGS002340
(blood_MEAN_PLATELET_VOL.BOLT-LMM)
PSS009804|
East Asian Ancestry|
892 individuals
PGP000332 |
Weissbrod O et al. Nat Genet (2022)
Reported Trait: Mean Platelet Volume Incremental R2 (full model vs. covariates alone): 0.1872 age, sex, age*sex, assessment center, genotyping array, 10 PCs
PPM013203 PGS002340
(blood_MEAN_PLATELET_VOL.BOLT-LMM)
PSS009805|
European Ancestry|
42,078 individuals
PGP000332 |
Weissbrod O et al. Nat Genet (2022)
Reported Trait: Mean Platelet Volume Incremental R2 (full model vs. covariates alone): 0.3575 age, sex, age*sex, assessment center, genotyping array, 10 PCs
PPM013252 PGS002340
(blood_MEAN_PLATELET_VOL.BOLT-LMM)
PSS009806|
South Asian Ancestry|
7,770 individuals
PGP000332 |
Weissbrod O et al. Nat Genet (2022)
Reported Trait: Mean Platelet Volume Incremental R2 (full model vs. covariates alone): 0.259 age, sex, age*sex, assessment center, genotyping array, 10 PCs
PPM013393 PGS002412
(blood_MEAN_PLATELET_VOL.P+T.0.0001)
PSS009803|
African Ancestry|
6,153 individuals
PGP000332 |
Weissbrod O et al. Nat Genet (2022)
Reported Trait: Mean Platelet Volume Incremental R2 (full model vs. covariates alone): 0.0202 age, sex, age*sex, assessment center, genotyping array, 10 PCs
PPM013442 PGS002412
(blood_MEAN_PLATELET_VOL.P+T.0.0001)
PSS009804|
East Asian Ancestry|
892 individuals
PGP000332 |
Weissbrod O et al. Nat Genet (2022)
Reported Trait: Mean Platelet Volume Incremental R2 (full model vs. covariates alone): 0.1256 age, sex, age*sex, assessment center, genotyping array, 10 PCs
PPM013491 PGS002412
(blood_MEAN_PLATELET_VOL.P+T.0.0001)
PSS009805|
European Ancestry|
42,078 individuals
PGP000332 |
Weissbrod O et al. Nat Genet (2022)
Reported Trait: Mean Platelet Volume Incremental R2 (full model vs. covariates alone): 0.2484 age, sex, age*sex, assessment center, genotyping array, 10 PCs
PPM013540 PGS002412
(blood_MEAN_PLATELET_VOL.P+T.0.0001)
PSS009806|
South Asian Ancestry|
7,770 individuals
PGP000332 |
Weissbrod O et al. Nat Genet (2022)
Reported Trait: Mean Platelet Volume Incremental R2 (full model vs. covariates alone): 0.1677 age, sex, age*sex, assessment center, genotyping array, 10 PCs
PPM013638 PGS002461
(blood_MEAN_PLATELET_VOL.P+T.0.001)
PSS009804|
East Asian Ancestry|
892 individuals
PGP000332 |
Weissbrod O et al. Nat Genet (2022)
Reported Trait: Mean Platelet Volume Incremental R2 (full model vs. covariates alone): 0.1171 age, sex, age*sex, assessment center, genotyping array, 10 PCs
PPM013687 PGS002461
(blood_MEAN_PLATELET_VOL.P+T.0.001)
PSS009805|
European Ancestry|
42,078 individuals
PGP000332 |
Weissbrod O et al. Nat Genet (2022)
Reported Trait: Mean Platelet Volume Incremental R2 (full model vs. covariates alone): 0.2478 age, sex, age*sex, assessment center, genotyping array, 10 PCs
PPM013736 PGS002461
(blood_MEAN_PLATELET_VOL.P+T.0.001)
PSS009806|
South Asian Ancestry|
7,770 individuals
PGP000332 |
Weissbrod O et al. Nat Genet (2022)
Reported Trait: Mean Platelet Volume Incremental R2 (full model vs. covariates alone): 0.1579 age, sex, age*sex, assessment center, genotyping array, 10 PCs
PPM013589 PGS002461
(blood_MEAN_PLATELET_VOL.P+T.0.001)
PSS009803|
African Ancestry|
6,153 individuals
PGP000332 |
Weissbrod O et al. Nat Genet (2022)
Reported Trait: Mean Platelet Volume Incremental R2 (full model vs. covariates alone): 0.0039 age, sex, age*sex, assessment center, genotyping array, 10 PCs
PPM013785 PGS002510
(blood_MEAN_PLATELET_VOL.P+T.0.01)
PSS009803|
African Ancestry|
6,153 individuals
PGP000332 |
Weissbrod O et al. Nat Genet (2022)
Reported Trait: Mean Platelet Volume Incremental R2 (full model vs. covariates alone): 0.0014 age, sex, age*sex, assessment center, genotyping array, 10 PCs
PPM013834 PGS002510
(blood_MEAN_PLATELET_VOL.P+T.0.01)
PSS009804|
East Asian Ancestry|
892 individuals
PGP000332 |
Weissbrod O et al. Nat Genet (2022)
Reported Trait: Mean Platelet Volume Incremental R2 (full model vs. covariates alone): 0.0417 age, sex, age*sex, assessment center, genotyping array, 10 PCs
PPM013883 PGS002510
(blood_MEAN_PLATELET_VOL.P+T.0.01)
PSS009805|
European Ancestry|
42,078 individuals
PGP000332 |
Weissbrod O et al. Nat Genet (2022)
Reported Trait: Mean Platelet Volume Incremental R2 (full model vs. covariates alone): 0.1998 age, sex, age*sex, assessment center, genotyping array, 10 PCs
PPM013932 PGS002510
(blood_MEAN_PLATELET_VOL.P+T.0.01)
PSS009806|
South Asian Ancestry|
7,770 individuals
PGP000332 |
Weissbrod O et al. Nat Genet (2022)
Reported Trait: Mean Platelet Volume Incremental R2 (full model vs. covariates alone): 0.0686 age, sex, age*sex, assessment center, genotyping array, 10 PCs
PPM013981 PGS002559
(blood_MEAN_PLATELET_VOL.P+T.1e-06)
PSS009803|
African Ancestry|
6,153 individuals
PGP000332 |
Weissbrod O et al. Nat Genet (2022)
Reported Trait: Mean Platelet Volume Incremental R2 (full model vs. covariates alone): 0.0539 age, sex, age*sex, assessment center, genotyping array, 10 PCs
PPM014030 PGS002559
(blood_MEAN_PLATELET_VOL.P+T.1e-06)
PSS009804|
East Asian Ancestry|
892 individuals
PGP000332 |
Weissbrod O et al. Nat Genet (2022)
Reported Trait: Mean Platelet Volume Incremental R2 (full model vs. covariates alone): 0.114 age, sex, age*sex, assessment center, genotyping array, 10 PCs
PPM014079 PGS002559
(blood_MEAN_PLATELET_VOL.P+T.1e-06)
PSS009805|
European Ancestry|
42,078 individuals
PGP000332 |
Weissbrod O et al. Nat Genet (2022)
Reported Trait: Mean Platelet Volume Incremental R2 (full model vs. covariates alone): 0.2375 age, sex, age*sex, assessment center, genotyping array, 10 PCs
PPM014128 PGS002559
(blood_MEAN_PLATELET_VOL.P+T.1e-06)
PSS009806|
South Asian Ancestry|
7,770 individuals
PGP000332 |
Weissbrod O et al. Nat Genet (2022)
Reported Trait: Mean Platelet Volume Incremental R2 (full model vs. covariates alone): 0.1648 age, sex, age*sex, assessment center, genotyping array, 10 PCs
PPM014177 PGS002608
(blood_MEAN_PLATELET_VOL.P+T.5e-08)
PSS009803|
African Ancestry|
6,153 individuals
PGP000332 |
Weissbrod O et al. Nat Genet (2022)
Reported Trait: Mean Platelet Volume Incremental R2 (full model vs. covariates alone): 0.0528 age, sex, age*sex, assessment center, genotyping array, 10 PCs
PPM014226 PGS002608
(blood_MEAN_PLATELET_VOL.P+T.5e-08)
PSS009804|
East Asian Ancestry|
892 individuals
PGP000332 |
Weissbrod O et al. Nat Genet (2022)
Reported Trait: Mean Platelet Volume Incremental R2 (full model vs. covariates alone): 0.1077 age, sex, age*sex, assessment center, genotyping array, 10 PCs
PPM014275 PGS002608
(blood_MEAN_PLATELET_VOL.P+T.5e-08)
PSS009805|
European Ancestry|
42,078 individuals
PGP000332 |
Weissbrod O et al. Nat Genet (2022)
Reported Trait: Mean Platelet Volume Incremental R2 (full model vs. covariates alone): 0.2311 age, sex, age*sex, assessment center, genotyping array, 10 PCs
PPM014324 PGS002608
(blood_MEAN_PLATELET_VOL.P+T.5e-08)
PSS009806|
South Asian Ancestry|
7,770 individuals
PGP000332 |
Weissbrod O et al. Nat Genet (2022)
Reported Trait: Mean Platelet Volume Incremental R2 (full model vs. covariates alone): 0.1619 age, sex, age*sex, assessment center, genotyping array, 10 PCs
PPM014373 PGS002657
(blood_MEAN_PLATELET_VOL.PolyFun-pred)
PSS009803|
African Ancestry|
6,153 individuals
PGP000332 |
Weissbrod O et al. Nat Genet (2022)
Reported Trait: Mean Platelet Volume Incremental R2 (full model when combined with BOLT-LMM vs. covariates alone): 0.1611 age, sex, age*sex, assessment center, genotyping array, 10 PCs See blood_MEAN_PLATELET_VOL.mixweights file at http://data.broadinstitute.org/alkesgroup/polypred_results for combination weights
PPM014422 PGS002657
(blood_MEAN_PLATELET_VOL.PolyFun-pred)
PSS009804|
East Asian Ancestry|
892 individuals
PGP000332 |
Weissbrod O et al. Nat Genet (2022)
Reported Trait: Mean Platelet Volume Incremental R2 (full model when combined with BOLT-LMM vs. covariates alone): 0.2269 age, sex, age*sex, assessment center, genotyping array, 10 PCs See blood_MEAN_PLATELET_VOL.mixweights file at http://data.broadinstitute.org/alkesgroup/polypred_results for combination weights
PPM014471 PGS002657
(blood_MEAN_PLATELET_VOL.PolyFun-pred)
PSS009805|
European Ancestry|
42,078 individuals
PGP000332 |
Weissbrod O et al. Nat Genet (2022)
Reported Trait: Mean Platelet Volume Incremental R2 (full model when combined with BOLT-LMM vs. covariates alone): 0.3972 age, sex, age*sex, assessment center, genotyping array, 10 PCs See blood_MEAN_PLATELET_VOL.mixweights file at http://data.broadinstitute.org/alkesgroup/polypred_results for combination weights
PPM014520 PGS002657
(blood_MEAN_PLATELET_VOL.PolyFun-pred)
PSS009806|
South Asian Ancestry|
7,770 individuals
PGP000332 |
Weissbrod O et al. Nat Genet (2022)
Reported Trait: Mean Platelet Volume Incremental R2 (full model when combined with BOLT-LMM vs. covariates alone): 0.2957 age, sex, age*sex, assessment center, genotyping array, 10 PCs See blood_MEAN_PLATELET_VOL.mixweights file at http://data.broadinstitute.org/alkesgroup/polypred_results for combination weights
PPM014569 PGS002706
(blood_MEAN_PLATELET_VOL.SBayesR)
PSS009803|
African Ancestry|
6,153 individuals
PGP000332 |
Weissbrod O et al. Nat Genet (2022)
Reported Trait: Mean Platelet Volume Incremental R2 (full model vs. covariates alone): 0.1127 age, sex, age*sex, assessment center, genotyping array, 10 PCs
PPM014618 PGS002706
(blood_MEAN_PLATELET_VOL.SBayesR)
PSS009804|
East Asian Ancestry|
892 individuals
PGP000332 |
Weissbrod O et al. Nat Genet (2022)
Reported Trait: Mean Platelet Volume Incremental R2 (full model vs. covariates alone): 0.1723 age, sex, age*sex, assessment center, genotyping array, 10 PCs
PPM014667 PGS002706
(blood_MEAN_PLATELET_VOL.SBayesR)
PSS009805|
European Ancestry|
42,078 individuals
PGP000332 |
Weissbrod O et al. Nat Genet (2022)
Reported Trait: Mean Platelet Volume Incremental R2 (full model vs. covariates alone): 0.3475 age, sex, age*sex, assessment center, genotyping array, 10 PCs
PPM014716 PGS002706
(blood_MEAN_PLATELET_VOL.SBayesR)
PSS009806|
South Asian Ancestry|
7,770 individuals
PGP000332 |
Weissbrod O et al. Nat Genet (2022)
Reported Trait: Mean Platelet Volume Incremental R2 (full model vs. covariates alone): 0.2571 age, sex, age*sex, assessment center, genotyping array, 10 PCs
PPM017560 PGS003548
(cont-decay-log_platelet_volume)
PSS010829|
European Ancestry|
3,991 individuals
PGP000457 |
Ding Y et al. bioRxiv (2022)
|Pre
Reported Trait: Mean platelet (thrombocyte) volume partial-R2: 0.35 sex, age, deprivation index, PC1-16
PPM017644 PGS003548
(cont-decay-log_platelet_volume)
PSS010661|
European Ancestry|
6,278 individuals
PGP000457 |
Ding Y et al. bioRxiv (2022)
|Pre
Reported Trait: Mean platelet (thrombocyte) volume partial-R2: 0.31 sex, age, deprivation index, PC1-16
PPM017812 PGS003548
(cont-decay-log_platelet_volume)
PSS010241|
European Ancestry|
2,264 individuals
PGP000457 |
Ding Y et al. bioRxiv (2022)
|Pre
Reported Trait: Mean platelet (thrombocyte) volume partial-R2: 0.28 sex, age, deprivation index, PC1-16
PPM017896 PGS003548
(cont-decay-log_platelet_volume)
PSS010493|
South Asian Ancestry|
6,026 individuals
PGP000457 |
Ding Y et al. bioRxiv (2022)
|Pre
Reported Trait: Mean platelet (thrombocyte) volume partial-R2: 0.26 sex, age, deprivation index, PC1-16
PPM017980 PGS003548
(cont-decay-log_platelet_volume)
PSS010409|
East Asian Ancestry|
1,750 individuals
PGP000457 |
Ding Y et al. bioRxiv (2022)
|Pre
Reported Trait: Mean platelet (thrombocyte) volume partial-R2: 0.19 sex, age, deprivation index, PC1-16
PPM018064 PGS003548
(cont-decay-log_platelet_volume)
PSS010325|
African Ancestry|
2,330 individuals
PGP000457 |
Ding Y et al. bioRxiv (2022)
|Pre
Reported Trait: Mean platelet (thrombocyte) volume partial-R2: 0.1 sex, age, deprivation index, PC1-16
PPM018148 PGS003548
(cont-decay-log_platelet_volume)
PSS010745|
African Ancestry|
3,682 individuals
PGP000457 |
Ding Y et al. bioRxiv (2022)
|Pre
Reported Trait: Mean platelet (thrombocyte) volume partial-R2: 0.09 sex, age, deprivation index, PC1-16
PPM017476 PGS003548
(cont-decay-log_platelet_volume)
PSS010913|
European Ancestry|
19,418 individuals
PGP000457 |
Ding Y et al. bioRxiv (2022)
|Pre
Reported Trait: Mean platelet (thrombocyte) volume partial-R2: 0.34 sex, age, deprivation index, PC1-16
PPM017728 PGS003548
(cont-decay-log_platelet_volume)
PSS010577|
Greater Middle Eastern Ancestry|
1,123 individuals
PGP000457 |
Ding Y et al. bioRxiv (2022)
|Pre
Reported Trait: Mean platelet (thrombocyte) volume partial-R2: 0.26 sex, age, deprivation index, PC1-16
PPM018989 PGS003934
(INI30100)
PSS011144|
European Ancestry|
65,930 individuals
PGP000502 |
Tanigawa Y et al. AJHG (2023)
Reported Trait: Mean platelet (thrombocyte) volume : 0.36086 [0.35507, 0.36664]
PGS R2 (no covariates): 0.35829 [0.35251, 0.36408]
Incremental R2 (full-covars): 0.35783
age, sex, age^2, age*sex, Townsend deprivation index, genotype PCs (PC1-PC18)
PPM018990 PGS003934
(INI30100)
PSS011109|
European Ancestry|
2,813 individuals
PGP000502 |
Tanigawa Y et al. AJHG (2023)
Reported Trait: Mean platelet (thrombocyte) volume : 0.36427 [0.33635, 0.3922]
PGS R2 (no covariates): 0.35942 [0.33147, 0.38737]
Incremental R2 (full-covars): 0.35587
age, sex, age^2, age*sex, Townsend deprivation index, genotype PCs (PC1-PC18)
PPM018991 PGS003934
(INI30100)
PSS011113|
South Asian Ancestry|
1,433 individuals
PGP000502 |
Tanigawa Y et al. AJHG (2023)
Reported Trait: Mean platelet (thrombocyte) volume : 0.2322 [0.19468, 0.26972]
PGS R2 (no covariates): 0.23172 [0.19421, 0.26922]
Incremental R2 (full-covars): 0.22951
age, sex, age^2, age*sex, Townsend deprivation index, genotype PCs (PC1-PC18)
PPM018993 PGS003934
(INI30100)
PSS011166|
Multi-ancestry (excluding European)|
7,746 individuals
PGP000502 |
Tanigawa Y et al. AJHG (2023)
Reported Trait: Mean platelet (thrombocyte) volume : 0.30944 [0.29261, 0.32626]
PGS R2 (no covariates): 0.31539 [0.29855, 0.33222]
Incremental R2 (full-covars): 0.2903
age, sex, age^2, age*sex, Townsend deprivation index, genotype PCs (PC1-PC18)
PPM018992 PGS003934
(INI30100)
PSS011155|
African Ancestry|
1,157 individuals
PGP000502 |
Tanigawa Y et al. AJHG (2023)
Reported Trait: Mean platelet (thrombocyte) volume : 0.10997 [0.07685, 0.1431]
PGS R2 (no covariates): 0.10936 [0.0763, 0.14241]
Incremental R2 (full-covars): 0.10916
age, sex, age^2, age*sex, Townsend deprivation index, genotype PCs (PC1-PC18)
PPM020469 PGS004354
(X30100.score)
PSS011364|
European Ancestry|
56,192 individuals
PGP000561 |
Jung H et al. Commun Biol (2024)
Reported Trait: Mean platelet (thrombocyte) volume PGS R2 (no covariates): 0.39954

Evaluated Samples

PGS Sample Set ID
(PSS)
Phenotype Definitions and Methods Participant Follow-up Time Sample Numbers Age of Study Participants Sample Ancestry Additional Ancestry Description Cohort(s) Additional Sample/Cohort Information
PSS010913 19,418 individuals,
46.0 % Male samples
Mean = 56.9 years
Sd = 7.9 years
European white British UKB
PSS011144 65,930 individuals European
(white British ancestry)
UKB
PSS010661 6,278 individuals,
45.0 % Male samples
Mean = 54.5 years
Sd = 8.4 years
European Italian UKB
PSS010409 1,750 individuals,
33.0 % Male samples
Mean = 52.5 years
Sd = 7.8 years
East Asian Chinese UKB
PSS011155 1,157 individuals African unspecified UKB
PSS008789 6,437 individuals European Italy (South Europe) UKB
PSS011166 7,746 individuals East Asian, Other admixed ancestry East Asian, Other admixed ancestry UKB
PSS007905 2,343 individuals African American or Afro-Caribbean Carribean UKB
PSS000290 2,314 individuals European
(French Canadian)
CARTaGENE
PSS000291 39,260 individuals European INTERVAL
PSS008563 1,153 individuals Greater Middle Eastern (Middle Eastern, North African or Persian) Iran (Middle East) UKB
PSS000911 13,989 individuals Greater Middle Eastern (Middle Eastern, North African or Persian)
(Qatari)
QBB
PSS009461 19,423 individuals European UK (+ Ireland) UKB
PSS010829 3,991 individuals,
38.0 % Male samples
Mean = 54.3 years
Sd = 7.5 years
European Polish UKB
PSS010577 1,123 individuals,
59.0 % Male samples
Mean = 52.0 years
Sd = 8.0 years
Greater Middle Eastern (Middle Eastern, North African or Persian) Iranian UKB
PSS010325 2,330 individuals,
37.0 % Male samples
Mean = 52.4 years
Sd = 8.0 years
African American or Afro-Caribbean Caribbean UKB
PSS009803 6,153 individuals African unspecified UKB
PSS009804 892 individuals East Asian UKB
PSS009805 42,078 individuals European Non-British European UKB
PSS009806 7,770 individuals South Asian UKB
PSS000143 37,224 individuals,
50.0 % Male samples
Mean = 43.8 years
Range = [18.0, 75.7] years
European INTERVAL
PSS009235 4,002 individuals European Poland (NE Europe) UKB
PSS008341 6,078 individuals South Asian India (South Asia) UKB
PSS010745 3,682 individuals,
47.0 % Male samples
Mean = 51.9 years
Sd = 8.1 years
African unspecified Nigerian UKB
PSS011364 56,192 individuals European UKB
PSS010493 6,026 individuals,
55.0 % Male samples
Mean = 53.3 years
Sd = 8.4 years
South Asian Indian UKB
PSS011109 2,813 individuals European
(non-white British ancestry)
UKB
PSS010241 2,264 individuals,
45.0 % Male samples
Mean = 58.0 years
Sd = 7.1 years
European Ashkenazi UKB
PSS000169 78,320 individuals,
46.0 % Male samples
Mean = 57.26 years
Range = [38.87, 70.99] years
European UKB
PSS011113 1,433 individuals South Asian UKB
PSS009009 3,711 individuals African unspecified Nigeria (West Africa) UKB
PSS006956 6,139 individuals African unspecified UKB
PSS006957 1,655 individuals East Asian UKB
PSS006958 24,175 individuals European non-white British ancestry UKB
PSS006959 7,520 individuals South Asian UKB
PSS006960 65,636 individuals European white British ancestry UKB Testing cohort (heldout set)
PSS008118 1,762 individuals East Asian China (East Asia) UKB