Trait: platelet crit

Experimental Factor Ontology (EFO) Information
Identifier EFO_0007985
Description
  • The proportion of blood volume that is occupied by platelets, expressed as a percentage.
Trait category
Hematological measurement
Synonyms 4 synonyms
  • PCT
  • platelet crit (PCT)
  • plateletcrit
  • plateletcrit (PCT)
Mapped term(s) CMO:0001349

Associated Polygenic Score(s)

Filter PGS by Participant Ancestry
Individuals included in:
G - Source of Variant Associations (GWAS)
D - Score Development/Training
E - PGS Evaluation
List of ancestries includes:
Display options:
Ancestry legend
Multi-ancestry (including European)
Multi-ancestry (excluding European)
African
East Asian
South Asian
Additional Asian Ancestries
European
Greater Middle Eastern
Hispanic or Latin American
Additional Diverse Ancestries
Not Reported
Polygenic Score ID & Name PGS Publication ID (PGP) Reported Trait Mapped Trait(s) (Ontology) Number of Variants Ancestry distribution Scoring File (FTP Link)
PGS000107
(pct)
PGP000051 |
Xu Y et al. bioRxiv (2020)
|Pre
Plateletcrit platelet crit 726
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000107/ScoringFiles/PGS000107.txt.gz
PGS000184
(pct)
PGP000078 |
Vuckovic D et al. Cell (2020)
Plateletcrit platelet crit 700
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000184/ScoringFiles/PGS000184.txt.gz

Performance Metrics

Disclaimer: The performance metrics are displayed as reported by the source studies. It is important to note that metrics are not necessarily comparable with each other. For example, metrics depend on the sample characteristics (described by the PGS Catalog Sample Set [PSS] ID), phenotyping, and statistical modelling. Please refer to the source publication for additional guidance on performance.

PGS Performance
Metric ID (PPM)
Evaluated Score PGS Sample Set ID
(PSS)
Performance Source Trait PGS Effect Sizes
(per SD change)
Classification Metrics Other Metrics Covariates Included in the Model PGS Performance:
Other Relevant Information
PPM000246 PGS000107
(pct)
PSS000172|
European Ancestry|
78,161 individuals
PGP000051 |
Xu Y et al. bioRxiv (2020)
|Pre
Reported Trait: Plateletcrit Pearson correlation coefficent (r): 0.4584 age, sex, 10 PCs of ancestry, lifestyle factors (diet, smoking, alcohol consumption), technical covariates (the time between venepuncture and full blood cell analysis, seasonal effects, centre of sample collection, time dependent drift of equipment, systematic differences in equipment) UKB Testing Set - these samples were held out from Score Development (regression training) but overlap with the samples used for variant selection (GWAS)
PPM000247 PGS000107
(pct)
PSS000146|
European Ancestry|
37,306 individuals
PGP000051 |
Xu Y et al. bioRxiv (2020)
|Pre
Reported Trait: Plateletcrit Pearson correlation coefficent (r): 0.4375 age, sex, 10 PCs of ancestry, lifestyle factors (diet, smoking, alcohol consumption), technical covariates (the time between venepuncture and full blood cell analysis, seasonal effects, centre of sample collection, time dependent drift of equipment, systematic differences in equipment)
PPM000538 PGS000184
(pct)
PSS000291|
European Ancestry|
39,260 individuals
PGP000078 |
Vuckovic D et al. Cell (2020)
Reported Trait: Plateletcrit : 0.1555 sex, age, 10 genetic PCs

Evaluated Samples

PGS Sample Set ID
(PSS)
Phenotype Definitions and Methods Participant Follow-up Time Sample Numbers Age of Study Participants Sample Ancestry Additional Ancestry Description Cohort(s) Additional Sample/Cohort Information
PSS000172 78,161 individuals,
46.0 % Male samples
Mean = 57.2 years
Range = [39.66, 72.91] years
European UKB
PSS000146 37,306 individuals,
49.0 % Male samples
Mean = 43.82 years
Range = [18.0, 76.4] years
European INTERVAL
PSS000291 39,260 individuals European INTERVAL