Trait: platelet crit

Experimental Factor Ontology (EFO) Information
Identifier EFO_0007985
Description
  • The proportion of blood volume that is occupied by platelets, expressed as a percentage.
Trait category
Hematological measurement
Synonyms 4 synonyms
  • PCT
  • plateletcrit (PCT)
  • platelet crit (PCT)
  • plateletcrit
Mapped term(s) CMO:0001349

Associated Polygenic Score(s)

Polygenic Score (PGS) ID PGS Name PGS Publication (PGP) ID Reported Trait Number of Variants PGS Scoring File (FTP Link)
PGS000107 pct PGP000051
Xu Y et al. bioRxiv (2020)
Plateletcrit 726 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000107/ScoringFiles/PGS000107.txt.gz

PGS Performance Metrics

Disclaimer: The performance metrics are displayed as reported by the source studies. It is important to note that metrics are not necessarily comparable with each other. For example, metrics depend on the sample characteristics (described by the PGS Catalog Sample Set [PSS] ID), phenotyping, and statistical modelling. Please refer to the source publication for additional guidance on performance.

PGS Performance Metric ID
(PPM ID)
Evaluated Score PGS Sample Set ID
(PSS ID)
Performance Source Trait PGS Effect Sizes
(per SD change)
PGS Classification Metrics Other Metrics Covariates Included in PGS Model PGS Performance: Other Relevant Information
PPM000246 PGS000107 (pct) PSS000172 PGP000051
Xu Y et al. (2020)
Reported Trait: Plateletcrit Pearson correlation coefficent (r): 0.4584 age, sex, 10 PCs of ancestry, lifestyle factors (diet, smoking, alcohol consumption), technical covariates (the time between venepuncture and full blood cell analysis, seasonal effects, centre of sample collection, time dependent drift of equipment, systematic differences in equipment) UKB Testing Set - these samples were held out from Score Development (regression training) but overlap with the samples used for variant selection (GWAS)
PPM000247 PGS000107 (pct) PSS000146 PGP000051
Xu Y et al. (2020)
Reported Trait: Plateletcrit Pearson correlation coefficent (r): 0.4375 age, sex, 10 PCs of ancestry, lifestyle factors (diet, smoking, alcohol consumption), technical covariates (the time between venepuncture and full blood cell analysis, seasonal effects, centre of sample collection, time dependent drift of equipment, systematic differences in equipment)

Evaluated Samples

PGS Sample Set ID
(PSS ID)
Detailed Phenotype Description Participant Follow-up Time Sample Numbers Age of Study Participants Sample Ancestry Additional Ancestry Description Cohort(s) Additional Sample/Cohort Information
PSS000172 78,161 individuals,
46.0 % Male samples
Mean = 57.2 years
Range = [39.66, 72.91] years
European UKB
PSS000146 37,306 individuals,
49.0 % Male samples
Mean = 43.82 years
Range = [18.0, 76.4] years
European INTERVAL