Trait: blood protein amount

Trait Information
Identifier OBA_VT0005416
Description The amount of a protein when measured in blood. [AUTO: patterns/patterns/entity_attribute_location]
Trait category
Other measurement
Synonym blood protein amount
Child trait(s) 3 child traits

Associated Polygenic Score(s)

Filter PGS by Participant Ancestry
Individuals included in:
G - Source of Variant Associations (GWAS)
D - Score Development/Training
E - PGS Evaluation
List of ancestries includes:
Display options:
Ancestry legend
Multi-ancestry (including European)
Multi-ancestry (excluding European)
African
East Asian
South Asian
Additional Asian Ancestries
European
Greater Middle Eastern
Hispanic or Latin American
Additional Diverse Ancestries
Not Reported
Note: This table shows all PGS for "blood protein amount" and any child terms of this trait in the EFO hierarchy by default.
Polygenic Score ID & Name PGS Publication ID (PGP) Reported Trait Mapped Trait(s) (Ontology) Number of Variants Ancestry distribution
GWAS
Dev
Eval
Scoring File (FTP Link)
PGS000217
(ADM)
PGP000089 |
Folkersen L et al. Nat Metab (2020)
Adrenomedullin (ADM) serum levels blood protein amount 552,254
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000217/ScoringFiles/PGS000217.txt.gz
PGS000218
(AGRP)
PGP000089 |
Folkersen L et al. Nat Metab (2020)
Agouti-related protein (AGRP) serum levels blood protein amount 552,121
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000218/ScoringFiles/PGS000218.txt.gz
PGS000219
(CA-125)
PGP000089 |
Folkersen L et al. Nat Metab (2020)
Ovarian cancer-related tumor marker CA 125 (CA-125) serum levels blood protein amount 553,819
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000219/ScoringFiles/PGS000219.txt.gz
PGS000220
(CCL20)
PGP000089 |
Folkersen L et al. Nat Metab (2020)
C-C motif chemokine 20 (CCL20) serum levels blood protein amount 551,989
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000220/ScoringFiles/PGS000220.txt.gz
PGS000221
(CCL3)
PGP000089 |
Folkersen L et al. Nat Metab (2020)
C-C motif chemokine 3 (CCL3) serum levels blood protein amount 552,347
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000221/ScoringFiles/PGS000221.txt.gz
PGS000222
(CCL4)
PGP000089 |
Folkersen L et al. Nat Metab (2020)
C-C motif chemokine 4 (CCL4) serum levels blood protein amount 552,214
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000222/ScoringFiles/PGS000222.txt.gz
PGS000223
(CD40)
PGP000089 |
Folkersen L et al. Nat Metab (2020)
Tumor necrosis factor receptor superfamily member 5 (CD40) serum levels blood protein amount 552,187
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000223/ScoringFiles/PGS000223.txt.gz
PGS000224
(CHI3L1)
PGP000089 |
Folkersen L et al. Nat Metab (2020)
Chitinase-3-like protein 1 (CHI3L1) serum levels blood protein amount 552,106
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000224/ScoringFiles/PGS000224.txt.gz
PGS000225
(CSF-1)
PGP000089 |
Folkersen L et al. Nat Metab (2020)
Macrophage colony-stimulating factor 1 (CSF-1) serum levels blood protein amount 552,163
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000225/ScoringFiles/PGS000225.txt.gz
PGS000226
(CSTB)
PGP000089 |
Folkersen L et al. Nat Metab (2020)
Cystatin-B (CSTB) serum levels blood protein amount 552,195
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000226/ScoringFiles/PGS000226.txt.gz
PGS000227
(CTSD)
PGP000089 |
Folkersen L et al. Nat Metab (2020)
Cathepsin D (CTSD) serum levels blood protein amount 552,134
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000227/ScoringFiles/PGS000227.txt.gz
PGS000228
(CTSL1)
PGP000089 |
Folkersen L et al. Nat Metab (2020)
Cathepsin L1 (CTSL1) serum levels blood protein amount 552,084
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000228/ScoringFiles/PGS000228.txt.gz
PGS000229
(CX3CL1)
PGP000089 |
Folkersen L et al. Nat Metab (2020)
Fractalkine (CX3CL1) serum levels blood protein amount 552,274
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000229/ScoringFiles/PGS000229.txt.gz
PGS000230
(CXCL1)
PGP000089 |
Folkersen L et al. Nat Metab (2020)
C-X-C motif chemokine 1 (CXCL1) serum levels blood protein amount 552,234
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000230/ScoringFiles/PGS000230.txt.gz
PGS000231
(CXCL16)
PGP000089 |
Folkersen L et al. Nat Metab (2020)
C-X-C motif chemokine 16 (CXCL16) serum levels blood protein amount 552,241
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000231/ScoringFiles/PGS000231.txt.gz
PGS000232
(CXCL6)
PGP000089 |
Folkersen L et al. Nat Metab (2020)
C-X-C motif chemokine 6 (CXCL6) serum levels blood protein amount 552,061
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000232/ScoringFiles/PGS000232.txt.gz
PGS000233
(Dkk-1)
PGP000089 |
Folkersen L et al. Nat Metab (2020)
Dickkopf-related protein 1 (Dkk-1) serum levels blood protein amount 552,067
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000233/ScoringFiles/PGS000233.txt.gz
PGS000234
(ECP)
PGP000089 |
Folkersen L et al. Nat Metab (2020)
Eosinophil cationic protein (ECP) serum levels blood protein amount 553,046
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000234/ScoringFiles/PGS000234.txt.gz
PGS000235
(EGF)
PGP000089 |
Folkersen L et al. Nat Metab (2020)
Epidermal growth factor (EGF) serum levels blood protein amount 553,163
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000235/ScoringFiles/PGS000235.txt.gz
PGS000236
(ESM-1)
PGP000089 |
Folkersen L et al. Nat Metab (2020)
Endothelial cell-specific molecule 1 (ESM-1) serum levels blood protein amount 553,240
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000236/ScoringFiles/PGS000236.txt.gz
PGS000237
(FABP4)
PGP000089 |
Folkersen L et al. Nat Metab (2020)
Fatty acid-binding protein, adipocyte (FABP4) serum levels blood protein amount 552,343
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000237/ScoringFiles/PGS000237.txt.gz
PGS000238
(FAS)
PGP000089 |
Folkersen L et al. Nat Metab (2020)
Tumor necrosis factor receptor superfamily member 6 (FAS) serum levels blood protein amount 552,335
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000238/ScoringFiles/PGS000238.txt.gz
PGS000239
(FGF-23)
PGP000089 |
Folkersen L et al. Nat Metab (2020)
Fibroblast growth factor 23 (FGF-23) serum levels blood protein amount 552,100
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000239/ScoringFiles/PGS000239.txt.gz
PGS000240
(FS)
PGP000089 |
Folkersen L et al. Nat Metab (2020)
Follistatin (FS) serum levels blood protein amount 552,138
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000240/ScoringFiles/PGS000240.txt.gz
PGS000241
(GAL)
PGP000089 |
Folkersen L et al. Nat Metab (2020)
Galanin peptides (GAL) serum levels blood protein amount 553,548
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000241/ScoringFiles/PGS000241.txt.gz
PGS000242
(Gal-3)
PGP000089 |
Folkersen L et al. Nat Metab (2020)
Galectin-3 (Gal-3) serum levels blood protein amount 552,282
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000242/ScoringFiles/PGS000242.txt.gz
PGS000243
(GDF-15)
PGP000089 |
Folkersen L et al. Nat Metab (2020)
Growth/differentiation factor 15 (GDF-15) serum levels blood protein amount 552,228
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000243/ScoringFiles/PGS000243.txt.gz
PGS000244
(GH)
PGP000089 |
Folkersen L et al. Nat Metab (2020)
Growth hormone (GH) serum levels blood protein amount 552,236
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000244/ScoringFiles/PGS000244.txt.gz
PGS000245
(HB-EGF)
PGP000089 |
Folkersen L et al. Nat Metab (2020)
Proheparin-binding EGF-like growth factor (HB-EGF) serum levels blood protein amount 552,108
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000245/ScoringFiles/PGS000245.txt.gz
PGS000246
(HGF)
PGP000089 |
Folkersen L et al. Nat Metab (2020)
Hepatocyte growth factor (HGF) serum levels blood protein amount 552,104
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000246/ScoringFiles/PGS000246.txt.gz
PGS000247
(hK11)
PGP000089 |
Folkersen L et al. Nat Metab (2020)
Kallikrein-11 (hK11) serum levels blood protein amount 553,239
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000247/ScoringFiles/PGS000247.txt.gz
PGS000248
(HSP_27)
PGP000089 |
Folkersen L et al. Nat Metab (2020)
Heat shock 27 kDa protein (HSP_27) serum levels blood protein amount 552,212
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000248/ScoringFiles/PGS000248.txt.gz
PGS000249
(IL-18)
PGP000089 |
Folkersen L et al. Nat Metab (2020)
Interleukin-18 (IL-18) serum levels blood protein amount 552,186
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000249/ScoringFiles/PGS000249.txt.gz
PGS000250
(IL-1ra)
PGP000089 |
Folkersen L et al. Nat Metab (2020)
Interleukin-1 receptor antagonist protein (IL-1ra) serum levels blood protein amount 551,917
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000250/ScoringFiles/PGS000250.txt.gz
PGS000251
(IL-27)
PGP000089 |
Folkersen L et al. Nat Metab (2020)
Interleukin-27 (IL-27) serum levels blood protein amount 552,026
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000251/ScoringFiles/PGS000251.txt.gz
PGS000252
(IL-6)
PGP000089 |
Folkersen L et al. Nat Metab (2020)
Interleukin-6 (IL-6) serum levels blood protein amount 552,426
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000252/ScoringFiles/PGS000252.txt.gz
PGS000253
(IL-6RA)
PGP000089 |
Folkersen L et al. Nat Metab (2020)
Interleukin-6 receptor subunit alpha (IL-6RA) serum levels blood protein amount 552,132
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000253/ScoringFiles/PGS000253.txt.gz
PGS000254
(IL-8)
PGP000089 |
Folkersen L et al. Nat Metab (2020)
Interleukin-8 (IL-8) serum levels blood protein amount 551,990
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000254/ScoringFiles/PGS000254.txt.gz
PGS000255
(IL16)
PGP000089 |
Folkersen L et al. Nat Metab (2020)
Pro-interleukin-16 (IL16) serum levels blood protein amount 551,884
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000255/ScoringFiles/PGS000255.txt.gz
PGS000256
(ITGB1BP2)
PGP000089 |
Folkersen L et al. Nat Metab (2020)
Melusin (ITGB1BP2) serum levels blood protein amount 552,423
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000256/ScoringFiles/PGS000256.txt.gz
PGS000257
(KIM-1)
PGP000089 |
Folkersen L et al. Nat Metab (2020)
Kidney injury molecule 1 (KIM-1) serum levels blood protein amount 552,062
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000257/ScoringFiles/PGS000257.txt.gz
PGS000258
(KLK6)
PGP000089 |
Folkersen L et al. Nat Metab (2020)
Kallikrein-6 (KLK6) serum levels blood protein amount 552,053
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000258/ScoringFiles/PGS000258.txt.gz
PGS000259
(LEP)
PGP000089 |
Folkersen L et al. Nat Metab (2020)
Leptin (LEP) serum levels blood protein amount 552,110
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000259/ScoringFiles/PGS000259.txt.gz
PGS000260
(LOX-1)
PGP000089 |
Folkersen L et al. Nat Metab (2020)
Lectin-like oxidized LDL receptor 1 (LOX-1) serum levels blood protein amount 552,045
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000260/ScoringFiles/PGS000260.txt.gz
PGS000261
(mAmP)
PGP000089 |
Folkersen L et al. Nat Metab (2020)
Membrane-bound aminopeptidase P (mAmP) serum levels blood protein amount 553,070
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000261/ScoringFiles/PGS000261.txt.gz
PGS000262
(MB)
PGP000089 |
Folkersen L et al. Nat Metab (2020)
Myoglobin (MB) serum levels blood protein amount 552,171
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000262/ScoringFiles/PGS000262.txt.gz
PGS000263
(MCP-1)
PGP000089 |
Folkersen L et al. Nat Metab (2020)
Monocyte chemotactic protein 1 (MCP-1) serum levels blood protein amount 552,000
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000263/ScoringFiles/PGS000263.txt.gz
PGS000264
(MMP-1)
PGP000089 |
Folkersen L et al. Nat Metab (2020)
Matrix metalloproteinase-1 (MMP-1) serum levels blood protein amount 552,116
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000264/ScoringFiles/PGS000264.txt.gz
PGS000265
(MMP-10)
PGP000089 |
Folkersen L et al. Nat Metab (2020)
Matrix metalloproteinase-10 (MMP-10) serum levels blood protein amount 552,072
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000265/ScoringFiles/PGS000265.txt.gz
PGS000266
(MMP-12)
PGP000089 |
Folkersen L et al. Nat Metab (2020)
Matrix metalloproteinase-12 (MMP-12) serum levels blood protein amount 552,021
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000266/ScoringFiles/PGS000266.txt.gz
PGS000267
(MMP-3)
PGP000089 |
Folkersen L et al. Nat Metab (2020)
Matrix metalloproteinase-3 (MMP-3) serum levels blood protein amount 552,328
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000267/ScoringFiles/PGS000267.txt.gz
PGS000268
(MMP-7)
PGP000089 |
Folkersen L et al. Nat Metab (2020)
Matrix metalloproteinase-7 (MMP-7) serum levels blood protein amount 552,052
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000268/ScoringFiles/PGS000268.txt.gz
PGS000269
(MPO)
PGP000089 |
Folkersen L et al. Nat Metab (2020)
Myeloperoxidase (MPO) serum levels blood protein amount 552,278
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000269/ScoringFiles/PGS000269.txt.gz
PGS000270
(NT-pro_BNP)
PGP000089 |
Folkersen L et al. Nat Metab (2020)
N-terminal prohormone brain natriuretic peptide (NT-pro_BNP) serum levels blood protein amount 554,137
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000270/ScoringFiles/PGS000270.txt.gz
PGS000271
(OPG)
PGP000089 |
Folkersen L et al. Nat Metab (2020)
Osteoprotegerin (OPG) serum levels blood protein amount 552,205
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000271/ScoringFiles/PGS000271.txt.gz
PGS000272
(PAPPA)
PGP000089 |
Folkersen L et al. Nat Metab (2020)
Pappalysin-1 (PAPPA) serum levels blood protein amount 552,298
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000272/ScoringFiles/PGS000272.txt.gz
PGS000273
(PAR-1)
PGP000089 |
Folkersen L et al. Nat Metab (2020)
Proteinase-activated receptor 1 (PAR-1) serum levels blood protein amount 552,202
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000273/ScoringFiles/PGS000273.txt.gz
PGS000274
(PDGF_subunit_B)
PGP000089 |
Folkersen L et al. Nat Metab (2020)
Platelet-derived growth factor subunit B (PDGF_subunit_B) serum levels blood protein amount 552,265
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000274/ScoringFiles/PGS000274.txt.gz
PGS000275
(PECAM-1)
PGP000089 |
Folkersen L et al. Nat Metab (2020)
Platelet endothelial cell adhesion molecule (PECAM-1) serum levels blood protein amount 552,010
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000275/ScoringFiles/PGS000275.txt.gz
PGS000276
(PlGF)
PGP000089 |
Folkersen L et al. Nat Metab (2020)
Placenta growth factor (PlGF) serum levels blood protein amount 552,275
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000276/ScoringFiles/PGS000276.txt.gz
PGS000277
(PSGL-1)
PGP000089 |
Folkersen L et al. Nat Metab (2020)
P-selectin glycoprotein ligand 1 (PSGL-1) serum levels blood protein amount 552,165
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000277/ScoringFiles/PGS000277.txt.gz
PGS000278
(PTX3)
PGP000089 |
Folkersen L et al. Nat Metab (2020)
Pentraxin-related protein PTX3 (PTX3) serum levels blood protein amount 552,474
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000278/ScoringFiles/PGS000278.txt.gz
PGS000279
(RAGE)
PGP000089 |
Folkersen L et al. Nat Metab (2020)
Receptor for advanced glycosylation end products (RAGE) serum levels blood protein amount 552,298
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000279/ScoringFiles/PGS000279.txt.gz
PGS000280
(REN)
PGP000089 |
Folkersen L et al. Nat Metab (2020)
Renin (REN) serum levels blood protein amount 552,078
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000280/ScoringFiles/PGS000280.txt.gz
PGS000281
(RETN)
PGP000089 |
Folkersen L et al. Nat Metab (2020)
Resistin (RETN) serum levels blood protein amount 552,002
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000281/ScoringFiles/PGS000281.txt.gz
PGS000282
(SCF)
PGP000089 |
Folkersen L et al. Nat Metab (2020)
Stem cell factor (SCF) serum levels blood protein amount 552,420
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000282/ScoringFiles/PGS000282.txt.gz
PGS000283
(SPON1)
PGP000089 |
Folkersen L et al. Nat Metab (2020)
Spondin-1 (SPON1) serum levels blood protein amount 552,703
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000283/ScoringFiles/PGS000283.txt.gz
PGS000284
(ST2)
PGP000089 |
Folkersen L et al. Nat Metab (2020)
ST2 protein (ST2) serum levels blood protein amount 552,006
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000284/ScoringFiles/PGS000284.txt.gz
PGS000285
(TF)
PGP000089 |
Folkersen L et al. Nat Metab (2020)
Tissue factor (TF) serum levels blood protein amount 552,228
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000285/ScoringFiles/PGS000285.txt.gz
PGS000286
(TM)
PGP000089 |
Folkersen L et al. Nat Metab (2020)
Thrombomodulin (TM) serum levels blood protein amount 552,241
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000286/ScoringFiles/PGS000286.txt.gz
PGS000287
(TNF-R1)
PGP000089 |
Folkersen L et al. Nat Metab (2020)
Tumor necrosis factor receptor 1 (TNF-R1) serum levels blood protein amount 552,317
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000287/ScoringFiles/PGS000287.txt.gz
PGS000288
(TNF-R2)
PGP000089 |
Folkersen L et al. Nat Metab (2020)
Tumor necrosis factor receptor 2 (TNF-R2) serum levels blood protein amount 552,185
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000288/ScoringFiles/PGS000288.txt.gz
PGS000289
(TNFSF14)
PGP000089 |
Folkersen L et al. Nat Metab (2020)
Tumor necrosis factor ligand superfamily member 14 (TNFSF14) serum levels blood protein amount 552,048
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000289/ScoringFiles/PGS000289.txt.gz
PGS000290
(TRAIL)
PGP000089 |
Folkersen L et al. Nat Metab (2020)
TNF-related apoptosis-inducing ligand (TRAIL) serum levels blood protein amount 552,279
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000290/ScoringFiles/PGS000290.txt.gz
PGS000291
(TRAIL-R2)
PGP000089 |
Folkersen L et al. Nat Metab (2020)
TNF-related apoptosis-inducing ligand receptor 2 (TRAIL-R2) serum levels blood protein amount 552,198
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000291/ScoringFiles/PGS000291.txt.gz
PGS000292
(TRANCE)
PGP000089 |
Folkersen L et al. Nat Metab (2020)
TNF-related activation-induced cytokine (TRANCE) serum levels blood protein amount 552,090
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000292/ScoringFiles/PGS000292.txt.gz
PGS000293
(U-PAR)
PGP000089 |
Folkersen L et al. Nat Metab (2020)
Urokinase plasminogen activator surface receptor (U-PAR) serum levels blood protein amount 552,048
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000293/ScoringFiles/PGS000293.txt.gz
PGS000294
(VEGF-A)
PGP000089 |
Folkersen L et al. Nat Metab (2020)
Vascular endothelial growth factor A (VEGF-A) serum levels blood protein amount 552,070
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000294/ScoringFiles/PGS000294.txt.gz
PGS000295
(VEGF-D)
PGP000089 |
Folkersen L et al. Nat Metab (2020)
Vascular endothelial growth factor D (VEGF-D) serum levels blood protein amount 551,905
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000295/ScoringFiles/PGS000295.txt.gz
PGS000668
(snpnet.Alanine_aminotransferase)
PGP000128 |
Sinnott-Armstrong N et al. Nat Genet (2021)
Alanine aminotransferase [U/L] serum alanine aminotransferase amount 12,076
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000668/ScoringFiles/PGS000668.txt.gz - Check Terms/Licenses
PGS000669
(snpnet.Albumin)
PGP000128 |
Sinnott-Armstrong N et al. Nat Genet (2021)
Albumin [g/L] serum albumin amount 11,912
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000669/ScoringFiles/PGS000669.txt.gz - Check Terms/Licenses
PGS000691
(snpnet.Non_albumin_protein)
PGP000128 |
Sinnott-Armstrong N et al. Nat Genet (2021)
Non-albumin protein [g/L] level of serum globulin type protein 18,670
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000691/ScoringFiles/PGS000691.txt.gz - Check Terms/Licenses
PGS000816
(GRS150_ALT)
PGP000201 |
Pazoki R et al. Nat Commun (2021)
Alanine transaminase serum alanine aminotransferase amount 150
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000816/ScoringFiles/PGS000816.txt.gz
PGS001081
(GBE_INI23027)
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
JC VP1 antigen for Human Polyomavirus JCV blood protein amount 9
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001081/ScoringFiles/PGS001081.txt.gz
PGS001082
(GBE_INI23028)
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
MC VP1 antigen for Merkel Cell Polyomavirus blood protein amount 143
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001082/ScoringFiles/PGS001082.txt.gz
PGS001407
(GBE_INI23022)
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
HTLV-1 gag antigen for Human T-Lymphotropic Virus 1 blood protein amount 66
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001407/ScoringFiles/PGS001407.txt.gz
PGS001886
(portability-PLR_albumin)
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Albumin serum albumin amount 60,423
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001886/ScoringFiles/PGS001886.txt.gz
PGS001940
(portability-PLR_log_ALT)
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Alanine aminotransferase serum alanine aminotransferase amount 51,849
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001940/ScoringFiles/PGS001940.txt.gz
PGS002099
(portability-ldpred2_albumin)
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Albumin serum albumin amount 816,264
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002099/ScoringFiles/PGS002099.txt.gz
PGS002158
(portability-ldpred2_log_ALT)
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Alanine aminotransferase serum alanine aminotransferase amount 774,274
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002158/ScoringFiles/PGS002158.txt.gz
PGS002732
(GRS_77)
PGP000341 |
Vujkovic M et al. Nat Genet (2022)
Chronic elevation of alanine aminotransferase serum alanine aminotransferase amount 77
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002732/ScoringFiles/PGS002732.txt.gz
PGS003342
(CVGRS_ALT)
PGP000405 |
Kim YJ et al. Nat Commun (2022)
Alanine aminotransferase level serum alanine aminotransferase amount 51
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003342/ScoringFiles/PGS003342.txt.gz
PGS003351
(ALLGRS_ALT)
PGP000405 |
Kim YJ et al. Nat Commun (2022)
Alanine aminotransferase level serum alanine aminotransferase amount 57
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003351/ScoringFiles/PGS003351.txt.gz
PGS003522
(cont-decay-log_ALT)
PGP000457 |
Ding Y et al. bioRxiv (2022)
|Pre
Alanine aminotransferase serum alanine aminotransferase amount 979,739
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003522/ScoringFiles/PGS003522.txt.gz
PGS004328
(X30600.score)
PGP000561 |
Jung H et al. Commun Biol (2024)
Albumin serum albumin amount 1,059,939
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004328/ScoringFiles/PGS004328.txt.gz
PGS004329
(X30620.score)
PGP000561 |
Jung H et al. Commun Biol (2024)
Alanine aminotransferase (U/L) serum alanine aminotransferase amount 1,059,939
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004329/ScoringFiles/PGS004329.txt.gz
PGS004707
(Albumin_PRSmix_eur)
PGP000604 |
Truong B et al. Cell Genom (2024)
Albumin serum albumin amount 589,303
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004707/ScoringFiles/PGS004707.txt.gz
PGS004708
(Albumin_PRSmix_sas)
PGP000604 |
Truong B et al. Cell Genom (2024)
Albumin serum albumin amount 2,071,924
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004708/ScoringFiles/PGS004708.txt.gz
PGS004709
(Albumin_PRSmixPlus_eur)
PGP000604 |
Truong B et al. Cell Genom (2024)
Albumin serum albumin amount 2,659,200
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004709/ScoringFiles/PGS004709.txt.gz
PGS004710
(Albumin_PRSmixPlus_sas)
PGP000604 |
Truong B et al. Cell Genom (2024)
Albumin serum albumin amount 2,071,924
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004710/ScoringFiles/PGS004710.txt.gz
PGS004715
(ALT_PRSmix_eur)
PGP000604 |
Truong B et al. Cell Genom (2024)
Alanine aminotransferase serum alanine aminotransferase amount 559,731
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004715/ScoringFiles/PGS004715.txt.gz
PGS004716
(ALT_PRSmix_sas)
PGP000604 |
Truong B et al. Cell Genom (2024)
Alanine aminotransferase serum alanine aminotransferase amount 2,283,693
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004716/ScoringFiles/PGS004716.txt.gz
PGS004717
(ALT_PRSmixPlus_eur)
PGP000604 |
Truong B et al. Cell Genom (2024)
Alanine aminotransferase serum alanine aminotransferase amount 1,051,633
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004717/ScoringFiles/PGS004717.txt.gz
PGS004718
(ALT_PRSmixPlus_sas)
PGP000604 |
Truong B et al. Cell Genom (2024)
Alanine aminotransferase serum alanine aminotransferase amount 2,283,693
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004718/ScoringFiles/PGS004718.txt.gz

Performance Metrics

Disclaimer: The performance metrics are displayed as reported by the source studies. It is important to note that metrics are not necessarily comparable with each other. For example, metrics depend on the sample characteristics (described by the PGS Catalog Sample Set [PSS] ID), phenotyping, and statistical modelling. Please refer to the source publication for additional guidance on performance.

PGS Performance
Metric ID (PPM)
Evaluated Score PGS Sample Set ID
(PSS)
Performance Source Trait PGS Effect Sizes
(per SD change)
Classification Metrics Other Metrics Covariates Included in the Model PGS Performance:
Other Relevant Information
PPM000689 PGS000217
(ADM)
PSS000364|
European Ancestry|
4,678 individuals
PGP000089 |
Folkersen L et al. Nat Metab (2020)
Reported Trait: Adrenomedullin (ADM) serum levels : 0.07313
R² difference (PGS+covariates vs. covariates only): 0.01413
age + sex + 10 genetic PCs The main manuscript further reports scores divided into genome-wide significant loci (major loci) and remaining polygenic loci, but this performance metric just reports the sum of both.
PPM000674 PGS000218
(AGRP)
PSS000364|
European Ancestry|
4,678 individuals
PGP000089 |
Folkersen L et al. Nat Metab (2020)
Reported Trait: Agouti-related protein (AGRP) serum levels : 0.0215
R² difference (PGS+covariates vs. covariates only): 0.0075
age + sex + 10 genetic PCs The main manuscript further reports scores divided into genome-wide significant loci (major loci) and remaining polygenic loci, but this performance metric just reports the sum of both.
PPM000687 PGS000219
(CA-125)
PSS000364|
European Ancestry|
4,678 individuals
PGP000089 |
Folkersen L et al. Nat Metab (2020)
Reported Trait: Ovarian cancer-related tumor marker CA 125 (CA-125) serum levels R² difference (PGS+covariates vs. covariates only): 0.01315
: 0.02315
age + sex + 10 genetic PCs The main manuscript further reports scores divided into genome-wide significant loci (major loci) and remaining polygenic loci, but this performance metric just reports the sum of both.
PPM000685 PGS000220
(CCL20)
PSS000364|
European Ancestry|
4,678 individuals
PGP000089 |
Folkersen L et al. Nat Metab (2020)
Reported Trait: C-C motif chemokine 20 (CCL20) serum levels R² difference (PGS+covariates vs. covariates only): 0.01158
: 0.02158
age + sex + 10 genetic PCs The main manuscript further reports scores divided into genome-wide significant loci (major loci) and remaining polygenic loci, but this performance metric just reports the sum of both.
PPM000726 PGS000221
(CCL3)
PSS000364|
European Ancestry|
4,678 individuals
PGP000089 |
Folkersen L et al. Nat Metab (2020)
Reported Trait: C-C motif chemokine 3 (CCL3) serum levels : 0.10469
R² difference (PGS+covariates vs. covariates only): 0.05869
age + sex + 10 genetic PCs The main manuscript further reports scores divided into genome-wide significant loci (major loci) and remaining polygenic loci, but this performance metric just reports the sum of both.
PPM000736 PGS000222
(CCL4)
PSS000364|
European Ancestry|
4,678 individuals
PGP000089 |
Folkersen L et al. Nat Metab (2020)
Reported Trait: C-C motif chemokine 4 (CCL4) serum levels : 0.13833
R² difference (PGS+covariates vs. covariates only): 0.11033
age + sex + 10 genetic PCs The main manuscript further reports scores divided into genome-wide significant loci (major loci) and remaining polygenic loci, but this performance metric just reports the sum of both.
PPM000717 PGS000223
(CD40)
PSS000364|
European Ancestry|
4,678 individuals
PGP000089 |
Folkersen L et al. Nat Metab (2020)
Reported Trait: Tumor necrosis factor receptor superfamily member 5 (CD40) serum levels : 0.04728
R² difference (PGS+covariates vs. covariates only): 0.04528
age + sex + 10 genetic PCs The main manuscript further reports scores divided into genome-wide significant loci (major loci) and remaining polygenic loci, but this performance metric just reports the sum of both.
PPM000729 PGS000224
(CHI3L1)
PSS000364|
European Ancestry|
4,678 individuals
PGP000089 |
Folkersen L et al. Nat Metab (2020)
Reported Trait: Chitinase-3-like protein 1 (CHI3L1) serum levels : 0.15424
R² difference (PGS+covariates vs. covariates only): 0.07924
age + sex + 10 genetic PCs The main manuscript further reports scores divided into genome-wide significant loci (major loci) and remaining polygenic loci, but this performance metric just reports the sum of both.
PPM000669 PGS000225
(CSF-1)
PSS000364|
European Ancestry|
4,678 individuals
PGP000089 |
Folkersen L et al. Nat Metab (2020)
Reported Trait: Macrophage colony-stimulating factor 1 (CSF-1) serum levels : 0.01849
R² difference (PGS+covariates vs. covariates only): 0.00549
age + sex + 10 genetic PCs The main manuscript further reports scores divided into genome-wide significant loci (major loci) and remaining polygenic loci, but this performance metric just reports the sum of both.
PPM000734 PGS000226
(CSTB)
PSS000364|
European Ancestry|
4,678 individuals
PGP000089 |
Folkersen L et al. Nat Metab (2020)
Reported Trait: Cystatin-B (CSTB) serum levels : 0.14472
R² difference (PGS+covariates vs. covariates only): 0.10072
age + sex + 10 genetic PCs The main manuscript further reports scores divided into genome-wide significant loci (major loci) and remaining polygenic loci, but this performance metric just reports the sum of both.
PPM000695 PGS000227
(CTSD)
PSS000364|
European Ancestry|
4,678 individuals
PGP000089 |
Folkersen L et al. Nat Metab (2020)
Reported Trait: Cathepsin D (CTSD) serum levels : 0.09886
R² difference (PGS+covariates vs. covariates only): 0.01786
age + sex + 10 genetic PCs The main manuscript further reports scores divided into genome-wide significant loci (major loci) and remaining polygenic loci, but this performance metric just reports the sum of both.
PPM000712 PGS000228
(CTSL1)
PSS000364|
European Ancestry|
4,678 individuals
PGP000089 |
Folkersen L et al. Nat Metab (2020)
Reported Trait: Cathepsin L1 (CTSL1) serum levels : 0.09752
R² difference (PGS+covariates vs. covariates only): 0.03852
age + sex + 10 genetic PCs The main manuscript further reports scores divided into genome-wide significant loci (major loci) and remaining polygenic loci, but this performance metric just reports the sum of both.
PPM000703 PGS000229
(CX3CL1)
PSS000364|
European Ancestry|
4,678 individuals
PGP000089 |
Folkersen L et al. Nat Metab (2020)
Reported Trait: Fractalkine (CX3CL1) serum levels : 0.03603
R² difference (PGS+covariates vs. covariates only): 0.02403
age + sex + 10 genetic PCs The main manuscript further reports scores divided into genome-wide significant loci (major loci) and remaining polygenic loci, but this performance metric just reports the sum of both.
PPM000730 PGS000230
(CXCL1)
PSS000364|
European Ancestry|
4,678 individuals
PGP000089 |
Folkersen L et al. Nat Metab (2020)
Reported Trait: C-X-C motif chemokine 1 (CXCL1) serum levels : 0.08781
R² difference (PGS+covariates vs. covariates only): 0.07981
age + sex + 10 genetic PCs The main manuscript further reports scores divided into genome-wide significant loci (major loci) and remaining polygenic loci, but this performance metric just reports the sum of both.
PPM000691 PGS000231
(CXCL16)
PSS000364|
European Ancestry|
4,678 individuals
PGP000089 |
Folkersen L et al. Nat Metab (2020)
Reported Trait: C-X-C motif chemokine 16 (CXCL16) serum levels : 0.01734
R² difference (PGS+covariates vs. covariates only): 0.01434
age + sex + 10 genetic PCs The main manuscript further reports scores divided into genome-wide significant loci (major loci) and remaining polygenic loci, but this performance metric just reports the sum of both.
PPM000740 PGS000232
(CXCL6)
PSS000364|
European Ancestry|
4,678 individuals
PGP000089 |
Folkersen L et al. Nat Metab (2020)
Reported Trait: C-X-C motif chemokine 6 (CXCL6) serum levels R² difference (PGS+covariates vs. covariates only): 0.1496
: 0.1536
age + sex + 10 genetic PCs The main manuscript further reports scores divided into genome-wide significant loci (major loci) and remaining polygenic loci, but this performance metric just reports the sum of both.
PPM000698 PGS000233
(Dkk-1)
PSS000364|
European Ancestry|
4,678 individuals
PGP000089 |
Folkersen L et al. Nat Metab (2020)
Reported Trait: Dickkopf-related protein 1 (Dkk-1) serum levels : 0.02226
R² difference (PGS+covariates vs. covariates only): 0.01926
age + sex + 10 genetic PCs The main manuscript further reports scores divided into genome-wide significant loci (major loci) and remaining polygenic loci, but this performance metric just reports the sum of both.
PPM000697 PGS000234
(ECP)
PSS000364|
European Ancestry|
4,678 individuals
PGP000089 |
Folkersen L et al. Nat Metab (2020)
Reported Trait: Eosinophil cationic protein (ECP) serum levels : 0.023
R² difference (PGS+covariates vs. covariates only): 0.019
age + sex + 10 genetic PCs The main manuscript further reports scores divided into genome-wide significant loci (major loci) and remaining polygenic loci, but this performance metric just reports the sum of both.
PPM000680 PGS000235
(EGF)
PSS000364|
European Ancestry|
4,678 individuals
PGP000089 |
Folkersen L et al. Nat Metab (2020)
Reported Trait: Epidermal growth factor (EGF) serum levels : 0.01262
R² difference (PGS+covariates vs. covariates only): 0.00962
age + sex + 10 genetic PCs The main manuscript further reports scores divided into genome-wide significant loci (major loci) and remaining polygenic loci, but this performance metric just reports the sum of both.
PPM000679 PGS000236
(ESM-1)
PSS000364|
European Ancestry|
4,678 individuals
PGP000089 |
Folkersen L et al. Nat Metab (2020)
Reported Trait: Endothelial cell-specific molecule 1 (ESM-1) serum levels : 0.03924
R² difference (PGS+covariates vs. covariates only): 0.00924
age + sex + 10 genetic PCs The main manuscript further reports scores divided into genome-wide significant loci (major loci) and remaining polygenic loci, but this performance metric just reports the sum of both.
PPM000677 PGS000237
(FABP4)
PSS000364|
European Ancestry|
4,678 individuals
PGP000089 |
Folkersen L et al. Nat Metab (2020)
Reported Trait: Fatty acid-binding protein, adipocyte (FABP4) serum levels : 0.14804
R² difference (PGS+covariates vs. covariates only): 0.00804
age + sex + 10 genetic PCs The main manuscript further reports scores divided into genome-wide significant loci (major loci) and remaining polygenic loci, but this performance metric just reports the sum of both.
PPM000704 PGS000238
(FAS)
PSS000364|
European Ancestry|
4,678 individuals
PGP000089 |
Folkersen L et al. Nat Metab (2020)
Reported Trait: Tumor necrosis factor receptor superfamily member 6 (FAS) serum levels : 0.08826
R² difference (PGS+covariates vs. covariates only): 0.02626
age + sex + 10 genetic PCs The main manuscript further reports scores divided into genome-wide significant loci (major loci) and remaining polygenic loci, but this performance metric just reports the sum of both.
PPM000692 PGS000239
(FGF-23)
PSS000364|
European Ancestry|
4,678 individuals
PGP000089 |
Folkersen L et al. Nat Metab (2020)
Reported Trait: Fibroblast growth factor 23 (FGF-23) serum levels : 0.01903
R² difference (PGS+covariates vs. covariates only): 0.01503
age + sex + 10 genetic PCs The main manuscript further reports scores divided into genome-wide significant loci (major loci) and remaining polygenic loci, but this performance metric just reports the sum of both.
PPM000684 PGS000240
(FS)
PSS000364|
European Ancestry|
4,678 individuals
PGP000089 |
Folkersen L et al. Nat Metab (2020)
Reported Trait: Follistatin (FS) serum levels R² difference (PGS+covariates vs. covariates only): 0.01152
: 0.05152
age + sex + 10 genetic PCs The main manuscript further reports scores divided into genome-wide significant loci (major loci) and remaining polygenic loci, but this performance metric just reports the sum of both.
PPM000707 PGS000241
(GAL)
PSS000364|
European Ancestry|
4,678 individuals
PGP000089 |
Folkersen L et al. Nat Metab (2020)
Reported Trait: Galanin peptides (GAL) serum levels : 0.07696
R² difference (PGS+covariates vs. covariates only): 0.02796
age + sex + 10 genetic PCs The main manuscript further reports scores divided into genome-wide significant loci (major loci) and remaining polygenic loci, but this performance metric just reports the sum of both.
PPM000721 PGS000242
(Gal-3)
PSS000364|
European Ancestry|
4,678 individuals
PGP000089 |
Folkersen L et al. Nat Metab (2020)
Reported Trait: Galectin-3 (Gal-3) serum levels : 0.11502
R² difference (PGS+covariates vs. covariates only): 0.05002
age + sex + 10 genetic PCs The main manuscript further reports scores divided into genome-wide significant loci (major loci) and remaining polygenic loci, but this performance metric just reports the sum of both.
PPM000718 PGS000243
(GDF-15)
PSS000364|
European Ancestry|
4,678 individuals
PGP000089 |
Folkersen L et al. Nat Metab (2020)
Reported Trait: Growth/differentiation factor 15 (GDF-15) serum levels R² difference (PGS+covariates vs. covariates only): 0.04577
: 0.19577
age + sex + 10 genetic PCs The main manuscript further reports scores divided into genome-wide significant loci (major loci) and remaining polygenic loci, but this performance metric just reports the sum of both.
PPM000665 PGS000244
(GH)
PSS000364|
European Ancestry|
4,678 individuals
PGP000089 |
Folkersen L et al. Nat Metab (2020)
Reported Trait: Growth hormone (GH) serum levels R² difference (PGS+covariates vs. covariates only): 0.00246
: 0.32546
age + sex + 10 genetic PCs The main manuscript further reports scores divided into genome-wide significant loci (major loci) and remaining polygenic loci, but this performance metric just reports the sum of both.
PPM000670 PGS000245
(HB-EGF)
PSS000364|
European Ancestry|
4,678 individuals
PGP000089 |
Folkersen L et al. Nat Metab (2020)
Reported Trait: Proheparin-binding EGF-like growth factor (HB-EGF) serum levels R² difference (PGS+covariates vs. covariates only): 0.00607
: 0.00807
age + sex + 10 genetic PCs The main manuscript further reports scores divided into genome-wide significant loci (major loci) and remaining polygenic loci, but this performance metric just reports the sum of both.
PPM000686 PGS000246
(HGF)
PSS000364|
European Ancestry|
4,678 individuals
PGP000089 |
Folkersen L et al. Nat Metab (2020)
Reported Trait: Hepatocyte growth factor (HGF) serum levels : 0.0741
R² difference (PGS+covariates vs. covariates only): 0.0131
age + sex + 10 genetic PCs The main manuscript further reports scores divided into genome-wide significant loci (major loci) and remaining polygenic loci, but this performance metric just reports the sum of both.
PPM000693 PGS000247
(hK11)
PSS000364|
European Ancestry|
4,678 individuals
PGP000089 |
Folkersen L et al. Nat Metab (2020)
Reported Trait: Kallikrein-11 (hK11) serum levels : 0.03621
R² difference (PGS+covariates vs. covariates only): 0.01721
age + sex + 10 genetic PCs The main manuscript further reports scores divided into genome-wide significant loci (major loci) and remaining polygenic loci, but this performance metric just reports the sum of both.
PPM000735 PGS000248
(HSP_27)
PSS000364|
European Ancestry|
4,678 individuals
PGP000089 |
Folkersen L et al. Nat Metab (2020)
Reported Trait: Heat shock 27 kDa protein (HSP_27) serum levels : 0.10996
R² difference (PGS+covariates vs. covariates only): 0.10196
age + sex + 10 genetic PCs The main manuscript further reports scores divided into genome-wide significant loci (major loci) and remaining polygenic loci, but this performance metric just reports the sum of both.
PPM000711 PGS000249
(IL-18)
PSS000364|
European Ancestry|
4,678 individuals
PGP000089 |
Folkersen L et al. Nat Metab (2020)
Reported Trait: Interleukin-18 (IL-18) serum levels : 0.08863
R² difference (PGS+covariates vs. covariates only): 0.03763
age + sex + 10 genetic PCs The main manuscript further reports scores divided into genome-wide significant loci (major loci) and remaining polygenic loci, but this performance metric just reports the sum of both.
PPM000714 PGS000250
(IL-1ra)
PSS000364|
European Ancestry|
4,678 individuals
PGP000089 |
Folkersen L et al. Nat Metab (2020)
Reported Trait: Interleukin-1 receptor antagonist protein (IL-1ra) serum levels : 0.05359
R² difference (PGS+covariates vs. covariates only): 0.03959
age + sex + 10 genetic PCs The main manuscript further reports scores divided into genome-wide significant loci (major loci) and remaining polygenic loci, but this performance metric just reports the sum of both.
PPM000733 PGS000251
(IL-27)
PSS000364|
European Ancestry|
4,678 individuals
PGP000089 |
Folkersen L et al. Nat Metab (2020)
Reported Trait: Interleukin-27 (IL-27) serum levels : 0.11711
R² difference (PGS+covariates vs. covariates only): 0.09911
age + sex + 10 genetic PCs The main manuscript further reports scores divided into genome-wide significant loci (major loci) and remaining polygenic loci, but this performance metric just reports the sum of both.
PPM000675 PGS000252
(IL-6)
PSS000364|
European Ancestry|
4,678 individuals
PGP000089 |
Folkersen L et al. Nat Metab (2020)
Reported Trait: Interleukin-6 (IL-6) serum levels : 0.01995
R² difference (PGS+covariates vs. covariates only): 0.00795
age + sex + 10 genetic PCs The main manuscript further reports scores divided into genome-wide significant loci (major loci) and remaining polygenic loci, but this performance metric just reports the sum of both.
PPM000742 PGS000253
(IL-6RA)
PSS000364|
European Ancestry|
4,678 individuals
PGP000089 |
Folkersen L et al. Nat Metab (2020)
Reported Trait: Interleukin-6 receptor subunit alpha (IL-6RA) serum levels : 0.31718
R² difference (PGS+covariates vs. covariates only): 0.28118
age + sex + 10 genetic PCs The main manuscript further reports scores divided into genome-wide significant loci (major loci) and remaining polygenic loci, but this performance metric just reports the sum of both.
PPM000666 PGS000254
(IL-8)
PSS000364|
European Ancestry|
4,678 individuals
PGP000089 |
Folkersen L et al. Nat Metab (2020)
Reported Trait: Interleukin-8 (IL-8) serum levels : 0.03298
R² difference (PGS+covariates vs. covariates only): 0.00298
age + sex + 10 genetic PCs The main manuscript further reports scores divided into genome-wide significant loci (major loci) and remaining polygenic loci, but this performance metric just reports the sum of both.
PPM000737 PGS000255
(IL16)
PSS000364|
European Ancestry|
4,678 individuals
PGP000089 |
Folkersen L et al. Nat Metab (2020)
Reported Trait: Pro-interleukin-16 (IL16) serum levels : 0.1446
R² difference (PGS+covariates vs. covariates only): 0.1136
age + sex + 10 genetic PCs The main manuscript further reports scores divided into genome-wide significant loci (major loci) and remaining polygenic loci, but this performance metric just reports the sum of both.
PPM000667 PGS000256
(ITGB1BP2)
PSS000364|
European Ancestry|
4,678 individuals
PGP000089 |
Folkersen L et al. Nat Metab (2020)
Reported Trait: Melusin (ITGB1BP2) serum levels : 0.00624
R² difference (PGS+covariates vs. covariates only): 0.00324
age + sex + 10 genetic PCs The main manuscript further reports scores divided into genome-wide significant loci (major loci) and remaining polygenic loci, but this performance metric just reports the sum of both.
PPM000739 PGS000257
(KIM-1)
PSS000364|
European Ancestry|
4,678 individuals
PGP000089 |
Folkersen L et al. Nat Metab (2020)
Reported Trait: Kidney injury molecule 1 (KIM-1) serum levels : 0.22579
R² difference (PGS+covariates vs. covariates only): 0.13579
age + sex + 10 genetic PCs The main manuscript further reports scores divided into genome-wide significant loci (major loci) and remaining polygenic loci, but this performance metric just reports the sum of both.
PPM000696 PGS000258
(KLK6)
PSS000364|
European Ancestry|
4,678 individuals
PGP000089 |
Folkersen L et al. Nat Metab (2020)
Reported Trait: Kallikrein-6 (KLK6) serum levels : 0.03607
R² difference (PGS+covariates vs. covariates only): 0.01807
age + sex + 10 genetic PCs The main manuscript further reports scores divided into genome-wide significant loci (major loci) and remaining polygenic loci, but this performance metric just reports the sum of both.
PPM000672 PGS000259
(LEP)
PSS000364|
European Ancestry|
4,678 individuals
PGP000089 |
Folkersen L et al. Nat Metab (2020)
Reported Trait: Leptin (LEP) serum levels : 0.32983
R² difference (PGS+covariates vs. covariates only): 0.00683
age + sex + 10 genetic PCs The main manuscript further reports scores divided into genome-wide significant loci (major loci) and remaining polygenic loci, but this performance metric just reports the sum of both.
PPM000681 PGS000260
(LOX-1)
PSS000364|
European Ancestry|
4,678 individuals
PGP000089 |
Folkersen L et al. Nat Metab (2020)
Reported Trait: Lectin-like oxidized LDL receptor 1 (LOX-1) serum levels : 0.01745
R² difference (PGS+covariates vs. covariates only): 0.01045
age + sex + 10 genetic PCs The main manuscript further reports scores divided into genome-wide significant loci (major loci) and remaining polygenic loci, but this performance metric just reports the sum of both.
PPM000694 PGS000261
(mAmP)
PSS000364|
European Ancestry|
4,678 individuals
PGP000089 |
Folkersen L et al. Nat Metab (2020)
Reported Trait: Membrane-bound aminopeptidase P (mAmP) serum levels : 0.02085
R² difference (PGS+covariates vs. covariates only): 0.01785
age + sex + 10 genetic PCs The main manuscript further reports scores divided into genome-wide significant loci (major loci) and remaining polygenic loci, but this performance metric just reports the sum of both.
PPM000683 PGS000262
(MB)
PSS000364|
European Ancestry|
4,678 individuals
PGP000089 |
Folkersen L et al. Nat Metab (2020)
Reported Trait: Myoglobin (MB) serum levels : 0.14211
R² difference (PGS+covariates vs. covariates only): 0.01111
age + sex + 10 genetic PCs The main manuscript further reports scores divided into genome-wide significant loci (major loci) and remaining polygenic loci, but this performance metric just reports the sum of both.
PPM000702 PGS000263
(MCP-1)
PSS000364|
European Ancestry|
4,678 individuals
PGP000089 |
Folkersen L et al. Nat Metab (2020)
Reported Trait: Monocyte chemotactic protein 1 (MCP-1) serum levels : 0.04833
R² difference (PGS+covariates vs. covariates only): 0.02333
age + sex + 10 genetic PCs The main manuscript further reports scores divided into genome-wide significant loci (major loci) and remaining polygenic loci, but this performance metric just reports the sum of both.
PPM000738 PGS000264
(MMP-1)
PSS000364|
European Ancestry|
4,678 individuals
PGP000089 |
Folkersen L et al. Nat Metab (2020)
Reported Trait: Matrix metalloproteinase-1 (MMP-1) serum levels : 0.2112
R² difference (PGS+covariates vs. covariates only): 0.1192
age + sex + 10 genetic PCs The main manuscript further reports scores divided into genome-wide significant loci (major loci) and remaining polygenic loci, but this performance metric just reports the sum of both.
PPM000722 PGS000265
(MMP-10)
PSS000364|
European Ancestry|
4,678 individuals
PGP000089 |
Folkersen L et al. Nat Metab (2020)
Reported Trait: Matrix metalloproteinase-10 (MMP-10) serum levels : 0.0618
R² difference (PGS+covariates vs. covariates only): 0.0518
age + sex + 10 genetic PCs The main manuscript further reports scores divided into genome-wide significant loci (major loci) and remaining polygenic loci, but this performance metric just reports the sum of both.
PPM000731 PGS000266
(MMP-12)
PSS000364|
European Ancestry|
4,678 individuals
PGP000089 |
Folkersen L et al. Nat Metab (2020)
Reported Trait: Matrix metalloproteinase-12 (MMP-12) serum levels : 0.08867
R² difference (PGS+covariates vs. covariates only): 0.08867
age + sex + 10 genetic PCs The main manuscript further reports scores divided into genome-wide significant loci (major loci) and remaining polygenic loci, but this performance metric just reports the sum of both.
PPM000728 PGS000267
(MMP-3)
PSS000364|
European Ancestry|
4,678 individuals
PGP000089 |
Folkersen L et al. Nat Metab (2020)
Reported Trait: Matrix metalloproteinase-3 (MMP-3) serum levels : 0.40253
R² difference (PGS+covariates vs. covariates only): 0.06753
age + sex + 10 genetic PCs The main manuscript further reports scores divided into genome-wide significant loci (major loci) and remaining polygenic loci, but this performance metric just reports the sum of both.
PPM000701 PGS000268
(MMP-7)
PSS000364|
European Ancestry|
4,678 individuals
PGP000089 |
Folkersen L et al. Nat Metab (2020)
Reported Trait: Matrix metalloproteinase-7 (MMP-7) serum levels : 0.0571
R² difference (PGS+covariates vs. covariates only): 0.0221
age + sex + 10 genetic PCs The main manuscript further reports scores divided into genome-wide significant loci (major loci) and remaining polygenic loci, but this performance metric just reports the sum of both.
PPM000719 PGS000269
(MPO)
PSS000364|
European Ancestry|
4,678 individuals
PGP000089 |
Folkersen L et al. Nat Metab (2020)
Reported Trait: Myeloperoxidase (MPO) serum levels R² difference (PGS+covariates vs. covariates only): 0.04865
: 0.05565
age + sex + 10 genetic PCs The main manuscript further reports scores divided into genome-wide significant loci (major loci) and remaining polygenic loci, but this performance metric just reports the sum of both.
PPM000664 PGS000270
(NT-pro_BNP)
PSS000364|
European Ancestry|
4,678 individuals
PGP000089 |
Folkersen L et al. Nat Metab (2020)
Reported Trait: N-terminal prohormone brain natriuretic peptide (NT-pro_BNP) serum levels R² difference (PGS+covariates vs. covariates only): 0.00108
: 0.07108
age + sex + 10 genetic PCs The main manuscript further reports scores divided into genome-wide significant loci (major loci) and remaining polygenic loci, but this performance metric just reports the sum of both.
PPM000699 PGS000271
(OPG)
PSS000364|
European Ancestry|
4,678 individuals
PGP000089 |
Folkersen L et al. Nat Metab (2020)
Reported Trait: Osteoprotegerin (OPG) serum levels : 0.09428
R² difference (PGS+covariates vs. covariates only): 0.02128
age + sex + 10 genetic PCs The main manuscript further reports scores divided into genome-wide significant loci (major loci) and remaining polygenic loci, but this performance metric just reports the sum of both.
PPM000720 PGS000272
(PAPPA)
PSS000364|
European Ancestry|
4,678 individuals
PGP000089 |
Folkersen L et al. Nat Metab (2020)
Reported Trait: Pappalysin-1 (PAPPA) serum levels : 0.14698
R² difference (PGS+covariates vs. covariates only): 0.04998
age + sex + 10 genetic PCs The main manuscript further reports scores divided into genome-wide significant loci (major loci) and remaining polygenic loci, but this performance metric just reports the sum of both.
PPM000678 PGS000273
(PAR-1)
PSS000364|
European Ancestry|
4,678 individuals
PGP000089 |
Folkersen L et al. Nat Metab (2020)
Reported Trait: Proteinase-activated receptor 1 (PAR-1) serum levels : 0.01206
R² difference (PGS+covariates vs. covariates only): 0.00906
age + sex + 10 genetic PCs The main manuscript further reports scores divided into genome-wide significant loci (major loci) and remaining polygenic loci, but this performance metric just reports the sum of both.
PPM000668 PGS000274
(PDGF_subunit_B)
PSS000364|
European Ancestry|
4,678 individuals
PGP000089 |
Folkersen L et al. Nat Metab (2020)
Reported Trait: Platelet-derived growth factor subunit B (PDGF_subunit_B) serum levels : 0.00734
R² difference (PGS+covariates vs. covariates only): 0.00434
age + sex + 10 genetic PCs The main manuscript further reports scores divided into genome-wide significant loci (major loci) and remaining polygenic loci, but this performance metric just reports the sum of both.
PPM000725 PGS000275
(PECAM-1)
PSS000364|
European Ancestry|
4,678 individuals
PGP000089 |
Folkersen L et al. Nat Metab (2020)
Reported Trait: Platelet endothelial cell adhesion molecule (PECAM-1) serum levels : 0.07059
R² difference (PGS+covariates vs. covariates only): 0.05759
age + sex + 10 genetic PCs The main manuscript further reports scores divided into genome-wide significant loci (major loci) and remaining polygenic loci, but this performance metric just reports the sum of both.
PPM000671 PGS000276
(PlGF)
PSS000364|
European Ancestry|
4,678 individuals
PGP000089 |
Folkersen L et al. Nat Metab (2020)
Reported Trait: Placenta growth factor (PlGF) serum levels : 0.09579
R² difference (PGS+covariates vs. covariates only): 0.00679
age + sex + 10 genetic PCs The main manuscript further reports scores divided into genome-wide significant loci (major loci) and remaining polygenic loci, but this performance metric just reports the sum of both.
PPM000682 PGS000277
(PSGL-1)
PSS000364|
European Ancestry|
4,678 individuals
PGP000089 |
Folkersen L et al. Nat Metab (2020)
Reported Trait: P-selectin glycoprotein ligand 1 (PSGL-1) serum levels : 0.01086
R² difference (PGS+covariates vs. covariates only): 0.01086
age + sex + 10 genetic PCs The main manuscript further reports scores divided into genome-wide significant loci (major loci) and remaining polygenic loci, but this performance metric just reports the sum of both.
PPM000708 PGS000278
(PTX3)
PSS000364|
European Ancestry|
4,678 individuals
PGP000089 |
Folkersen L et al. Nat Metab (2020)
Reported Trait: Pentraxin-related protein PTX3 (PTX3) serum levels : 0.03012
R² difference (PGS+covariates vs. covariates only): 0.02812
age + sex + 10 genetic PCs The main manuscript further reports scores divided into genome-wide significant loci (major loci) and remaining polygenic loci, but this performance metric just reports the sum of both.
PPM000705 PGS000279
(RAGE)
PSS000364|
European Ancestry|
4,678 individuals
PGP000089 |
Folkersen L et al. Nat Metab (2020)
Reported Trait: Receptor for advanced glycosylation end products (RAGE) serum levels : 0.04312
R² difference (PGS+covariates vs. covariates only): 0.02712
age + sex + 10 genetic PCs The main manuscript further reports scores divided into genome-wide significant loci (major loci) and remaining polygenic loci, but this performance metric just reports the sum of both.
PPM000673 PGS000280
(REN)
PSS000364|
European Ancestry|
4,678 individuals
PGP000089 |
Folkersen L et al. Nat Metab (2020)
Reported Trait: Renin (REN) serum levels : 0.08537
R² difference (PGS+covariates vs. covariates only): 0.00737
age + sex + 10 genetic PCs The main manuscript further reports scores divided into genome-wide significant loci (major loci) and remaining polygenic loci, but this performance metric just reports the sum of both.
PPM000709 PGS000281
(RETN)
PSS000364|
European Ancestry|
4,678 individuals
PGP000089 |
Folkersen L et al. Nat Metab (2020)
Reported Trait: Resistin (RETN) serum levels : 0.04427
R² difference (PGS+covariates vs. covariates only): 0.03327
age + sex + 10 genetic PCs The main manuscript further reports scores divided into genome-wide significant loci (major loci) and remaining polygenic loci, but this performance metric just reports the sum of both.
PPM000723 PGS000282
(SCF)
PSS000364|
European Ancestry|
4,678 individuals
PGP000089 |
Folkersen L et al. Nat Metab (2020)
Reported Trait: Stem cell factor (SCF) serum levels : 0.05956
R² difference (PGS+covariates vs. covariates only): 0.05256
age + sex + 10 genetic PCs The main manuscript further reports scores divided into genome-wide significant loci (major loci) and remaining polygenic loci, but this performance metric just reports the sum of both.
PPM000706 PGS000283
(SPON1)
PSS000364|
European Ancestry|
4,678 individuals
PGP000089 |
Folkersen L et al. Nat Metab (2020)
Reported Trait: Spondin-1 (SPON1) serum levels : 0.06873
R² difference (PGS+covariates vs. covariates only): 0.02773
age + sex + 10 genetic PCs The main manuscript further reports scores divided into genome-wide significant loci (major loci) and remaining polygenic loci, but this performance metric just reports the sum of both.
PPM000741 PGS000284
(ST2)
PSS000364|
European Ancestry|
4,678 individuals
PGP000089 |
Folkersen L et al. Nat Metab (2020)
Reported Trait: ST2 protein (ST2) serum levels : 0.32939
R² difference (PGS+covariates vs. covariates only): 0.19039
age + sex + 10 genetic PCs The main manuscript further reports scores divided into genome-wide significant loci (major loci) and remaining polygenic loci, but this performance metric just reports the sum of both.
PPM000727 PGS000285
(TF)
PSS000364|
European Ancestry|
4,678 individuals
PGP000089 |
Folkersen L et al. Nat Metab (2020)
Reported Trait: Tissue factor (TF) serum levels : 0.10251
R² difference (PGS+covariates vs. covariates only): 0.06551
age + sex + 10 genetic PCs The main manuscript further reports scores divided into genome-wide significant loci (major loci) and remaining polygenic loci, but this performance metric just reports the sum of both.
PPM000710 PGS000286
(TM)
PSS000364|
European Ancestry|
4,678 individuals
PGP000089 |
Folkersen L et al. Nat Metab (2020)
Reported Trait: Thrombomodulin (TM) serum levels : 0.08819
R² difference (PGS+covariates vs. covariates only): 0.03619
age + sex + 10 genetic PCs The main manuscript further reports scores divided into genome-wide significant loci (major loci) and remaining polygenic loci, but this performance metric just reports the sum of both.
PPM000676 PGS000287
(TNF-R1)
PSS000364|
European Ancestry|
4,678 individuals
PGP000089 |
Folkersen L et al. Nat Metab (2020)
Reported Trait: Tumor necrosis factor receptor 1 (TNF-R1) serum levels : 0.06801
R² difference (PGS+covariates vs. covariates only): 0.00801
age + sex + 10 genetic PCs The main manuscript further reports scores divided into genome-wide significant loci (major loci) and remaining polygenic loci, but this performance metric just reports the sum of both.
PPM000688 PGS000288
(TNF-R2)
PSS000364|
European Ancestry|
4,678 individuals
PGP000089 |
Folkersen L et al. Nat Metab (2020)
Reported Trait: Tumor necrosis factor receptor 2 (TNF-R2) serum levels : 0.05136
R² difference (PGS+covariates vs. covariates only): 0.01336
age + sex + 10 genetic PCs The main manuscript further reports scores divided into genome-wide significant loci (major loci) and remaining polygenic loci, but this performance metric just reports the sum of both.
PPM000713 PGS000289
(TNFSF14)
PSS000364|
European Ancestry|
4,678 individuals
PGP000089 |
Folkersen L et al. Nat Metab (2020)
Reported Trait: Tumor necrosis factor ligand superfamily member 14 (TNFSF14) serum levels : 0.04311
R² difference (PGS+covariates vs. covariates only): 0.03911
age + sex + 10 genetic PCs The main manuscript further reports scores divided into genome-wide significant loci (major loci) and remaining polygenic loci, but this performance metric just reports the sum of both.
PPM000724 PGS000290
(TRAIL)
PSS000364|
European Ancestry|
4,678 individuals
PGP000089 |
Folkersen L et al. Nat Metab (2020)
Reported Trait: TNF-related apoptosis-inducing ligand (TRAIL) serum levels : 0.11259
R² difference (PGS+covariates vs. covariates only): 0.05259
age + sex + 10 genetic PCs The main manuscript further reports scores divided into genome-wide significant loci (major loci) and remaining polygenic loci, but this performance metric just reports the sum of both.
PPM000716 PGS000291
(TRAIL-R2)
PSS000364|
European Ancestry|
4,678 individuals
PGP000089 |
Folkersen L et al. Nat Metab (2020)
Reported Trait: TNF-related apoptosis-inducing ligand receptor 2 (TRAIL-R2) serum levels R² difference (PGS+covariates vs. covariates only): 0.04464
: 0.05164
age + sex + 10 genetic PCs The main manuscript further reports scores divided into genome-wide significant loci (major loci) and remaining polygenic loci, but this performance metric just reports the sum of both.
PPM000715 PGS000292
(TRANCE)
PSS000364|
European Ancestry|
4,678 individuals
PGP000089 |
Folkersen L et al. Nat Metab (2020)
Reported Trait: TNF-related activation-induced cytokine (TRANCE) serum levels : 0.0487
R² difference (PGS+covariates vs. covariates only): 0.0427
age + sex + 10 genetic PCs The main manuscript further reports scores divided into genome-wide significant loci (major loci) and remaining polygenic loci, but this performance metric just reports the sum of both.
PPM000690 PGS000293
(U-PAR)
PSS000364|
European Ancestry|
4,678 individuals
PGP000089 |
Folkersen L et al. Nat Metab (2020)
Reported Trait: Urokinase plasminogen activator surface receptor (U-PAR) serum levels : 0.03628
R² difference (PGS+covariates vs. covariates only): 0.01428
age + sex + 10 genetic PCs The main manuscript further reports scores divided into genome-wide significant loci (major loci) and remaining polygenic loci, but this performance metric just reports the sum of both.
PPM000732 PGS000294
(VEGF-A)
PSS000364|
European Ancestry|
4,678 individuals
PGP000089 |
Folkersen L et al. Nat Metab (2020)
Reported Trait: Vascular endothelial growth factor A (VEGF-A) serum levels : 0.10967
R² difference (PGS+covariates vs. covariates only): 0.08967
age + sex + 10 genetic PCs The main manuscript further reports scores divided into genome-wide significant loci (major loci) and remaining polygenic loci, but this performance metric just reports the sum of both.
PPM000700 PGS000295
(VEGF-D)
PSS000364|
European Ancestry|
4,678 individuals
PGP000089 |
Folkersen L et al. Nat Metab (2020)
Reported Trait: Vascular endothelial growth factor D (VEGF-D) serum levels : 0.0429
R² difference (PGS+covariates vs. covariates only): 0.0219
age + sex + 10 genetic PCs The main manuscript further reports scores divided into genome-wide significant loci (major loci) and remaining polygenic loci, but this performance metric just reports the sum of both.
PPM001466 PGS000668
(snpnet.Alanine_aminotransferase)
PSS000624|
European Ancestry|
23,569 individuals
PGP000128 |
Sinnott-Armstrong N et al. Nat Genet (2021)
Reported Trait: Alanine aminotransferase [U/L] : 0.2041
Spearman's ρ: 0.22
Age, sex, PCs(1-40)
PPM001501 PGS000668
(snpnet.Alanine_aminotransferase)
PSS000625|
South Asian Ancestry|
7,325 individuals
PGP000128 |
Sinnott-Armstrong N et al. Nat Genet (2021)
Reported Trait: Alanine aminotransferase [U/L] : 0.18304
Spearman's ρ: 0.198
Age, sex, PCs(1-40)
PPM001536 PGS000668
(snpnet.Alanine_aminotransferase)
PSS000626|
European Ancestry|
63,766 individuals
PGP000128 |
Sinnott-Armstrong N et al. Nat Genet (2021)
Reported Trait: Alanine aminotransferase [U/L] : 0.19165
Spearman's ρ: 0.244
Age, sex, PCs(1-40)
PPM001396 PGS000668
(snpnet.Alanine_aminotransferase)
PSS000622|
African Ancestry|
6,017 individuals
PGP000128 |
Sinnott-Armstrong N et al. Nat Genet (2021)
Reported Trait: Alanine aminotransferase [U/L] : 0.17646
Spearman's ρ: 0.092
Age, sex, PCs(1-40)
PPM001431 PGS000668
(snpnet.Alanine_aminotransferase)
PSS000623|
East Asian Ancestry|
1,081 individuals
PGP000128 |
Sinnott-Armstrong N et al. Nat Genet (2021)
Reported Trait: Alanine aminotransferase [U/L] : 0.1561
Spearman's ρ: 0.145
Age, sex, PCs(1-40)
PPM007267 PGS000668
(snpnet.Alanine_aminotransferase)
PSS007078|
European Ancestry|
23,758 individuals
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
|Ext.
Reported Trait: Alanine aminotransferase : 0.07978 [0.07332, 0.08623]
Incremental R2 (full-covars): 0.00218
PGS R2 (no covariates): 0.03 [0.02583, 0.03418]
age, sex, UKB array type, Genotype PCs
PPM007265 PGS000668
(snpnet.Alanine_aminotransferase)
PSS007076|
African Ancestry|
6,099 individuals
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
|Ext.
Reported Trait: Alanine aminotransferase : 0.0977 [0.084, 0.11141]
Incremental R2 (full-covars): 0.00077
PGS R2 (no covariates): 0.00447 [0.00124, 0.00771]
age, sex, UKB array type, Genotype PCs
PPM007266 PGS000668
(snpnet.Alanine_aminotransferase)
PSS007077|
East Asian Ancestry|
1,615 individuals
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
|Ext.
Reported Trait: Alanine aminotransferase : 0.08994 [0.06408, 0.11581]
Incremental R2 (full-covars): 0.00177
PGS R2 (no covariates): 0.02382 [0.00954, 0.03809]
age, sex, UKB array type, Genotype PCs
PPM007268 PGS000668
(snpnet.Alanine_aminotransferase)
PSS007079|
South Asian Ancestry|
7,414 individuals
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
|Ext.
Reported Trait: Alanine aminotransferase : 0.08504 [0.07323, 0.09685]
Incremental R2 (full-covars): 0.00213
PGS R2 (no covariates): 0.02862 [0.02135, 0.0359]
age, sex, UKB array type, Genotype PCs
PPM007269 PGS000668
(snpnet.Alanine_aminotransferase)
PSS007080|
European Ancestry|
64,440 individuals
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
|Ext.
Reported Trait: Alanine aminotransferase : 0.06901 [0.06532, 0.0727]
Incremental R2 (full-covars): 0.00284
PGS R2 (no covariates): 0.03994 [0.03705, 0.04284]
age, sex, UKB array type, Genotype PCs
PPM001397 PGS000669
(snpnet.Albumin)
PSS000627|
African Ancestry|
5,573 individuals
PGP000128 |
Sinnott-Armstrong N et al. Nat Genet (2021)
Reported Trait: Albumin [g/L] : 0.10081
Spearman's ρ: 0.121
Age, sex, PCs(1-40)
PPM001432 PGS000669
(snpnet.Albumin)
PSS000628|
East Asian Ancestry|
984 individuals
PGP000128 |
Sinnott-Armstrong N et al. Nat Genet (2021)
Reported Trait: Albumin [g/L] : 0.08916
Spearman's ρ: 0.198
Age, sex, PCs(1-40)
PPM001467 PGS000669
(snpnet.Albumin)
PSS000629|
European Ancestry|
21,516 individuals
PGP000128 |
Sinnott-Armstrong N et al. Nat Genet (2021)
Reported Trait: Albumin [g/L] : 0.13257
Spearman's ρ: 0.25
Age, sex, PCs(1-40)
PPM001502 PGS000669
(snpnet.Albumin)
PSS000630|
South Asian Ancestry|
6,687 individuals
PGP000128 |
Sinnott-Armstrong N et al. Nat Genet (2021)
Reported Trait: Albumin [g/L] : 0.15158
Spearman's ρ: 0.216
Age, sex, PCs(1-40)
PPM001537 PGS000669
(snpnet.Albumin)
PSS000631|
European Ancestry|
58,196 individuals
PGP000128 |
Sinnott-Armstrong N et al. Nat Genet (2021)
Reported Trait: Albumin [g/L] : 0.13054
Spearman's ρ: 0.262
Age, sex, PCs(1-40)
PPM007271 PGS000669
(snpnet.Albumin)
PSS007067|
East Asian Ancestry|
1,472 individuals
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
|Ext.
Reported Trait: Albumin : 0.02049 [0.0072, 0.03378]
Incremental R2 (full-covars): 0.00193
PGS R2 (no covariates): 0.05108 [0.03075, 0.0714]
age, sex, UKB array type, Genotype PCs
PPM007274 PGS000669
(snpnet.Albumin)
PSS007070|
European Ancestry|
59,097 individuals
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
|Ext.
Reported Trait: Albumin : 0.03793 [0.0351, 0.04076]
Incremental R2 (full-covars): 0.00267
PGS R2 (no covariates): 0.06779 [0.06413, 0.07145]
age, sex, UKB array type, Genotype PCs
PPM007270 PGS000669
(snpnet.Albumin)
PSS007066|
African Ancestry|
5,658 individuals
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
|Ext.
Reported Trait: Albumin : 0.07255 [0.06041, 0.08469]
Incremental R2 (full-covars): 0.00087
PGS R2 (no covariates): 0.01339 [0.00784, 0.01894]
age, sex, UKB array type, Genotype PCs
PPM007272 PGS000669
(snpnet.Albumin)
PSS007068|
European Ancestry|
21,759 individuals
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
|Ext.
Reported Trait: Albumin : 0.04362 [0.03866, 0.04859]
Incremental R2 (full-covars): 0.00252
PGS R2 (no covariates): 0.0618 [0.05601, 0.06759]
age, sex, UKB array type, Genotype PCs
PPM007273 PGS000669
(snpnet.Albumin)
PSS007069|
South Asian Ancestry|
6,786 individuals
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
|Ext.
Reported Trait: Albumin : 0.0904 [0.07829, 0.10251]
Incremental R2 (full-covars): 0.00198
PGS R2 (no covariates): 0.04739 [0.03821, 0.05657]
age, sex, UKB array type, Genotype PCs
PPM001419 PGS000691
(snpnet.Non_albumin_protein)
PSS000729|
African Ancestry|
5,573 individuals
PGP000128 |
Sinnott-Armstrong N et al. Nat Genet (2021)
Reported Trait: Non-albumin protein [g/L] : 0.07146
Spearman's ρ: 0.16
Age, sex, PCs(1-40)
PPM001454 PGS000691
(snpnet.Non_albumin_protein)
PSS000730|
East Asian Ancestry|
984 individuals
PGP000128 |
Sinnott-Armstrong N et al. Nat Genet (2021)
Reported Trait: Non-albumin protein [g/L] : 0.0886
Spearman's ρ: 0.216
Age, sex, PCs(1-40)
PPM001489 PGS000691
(snpnet.Non_albumin_protein)
PSS000731|
European Ancestry|
21,516 individuals
PGP000128 |
Sinnott-Armstrong N et al. Nat Genet (2021)
Reported Trait: Non-albumin protein [g/L] : 0.12839
Spearman's ρ: 0.31
Age, sex, PCs(1-40)
PPM001524 PGS000691
(snpnet.Non_albumin_protein)
PSS000732|
South Asian Ancestry|
6,687 individuals
PGP000128 |
Sinnott-Armstrong N et al. Nat Genet (2021)
Reported Trait: Non-albumin protein [g/L] : 0.15158
Spearman's ρ: 0.292
Age, sex, PCs(1-40)
PPM001559 PGS000691
(snpnet.Non_albumin_protein)
PSS000733|
European Ancestry|
58,196 individuals
PGP000128 |
Sinnott-Armstrong N et al. Nat Genet (2021)
Reported Trait: Non-albumin protein [g/L] : 0.12321
Spearman's ρ: 0.311
Age, sex, PCs(1-40)
PPM007380 PGS000691
(snpnet.Non_albumin_protein)
PSS006916|
African Ancestry|
5,573 individuals
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
|Ext.
Reported Trait: Non-albumin protein : 0.02946 [0.02136, 0.03756]
Incremental R2 (full-covars): 0.02412
PGS R2 (no covariates): 0.02397 [0.01663, 0.03132]
age, sex, UKB array type, Genotype PCs
PPM007381 PGS000691
(snpnet.Non_albumin_protein)
PSS006917|
East Asian Ancestry|
1,436 individuals
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
|Ext.
Reported Trait: Non-albumin protein : 0.09152 [0.06547, 0.11756]
Incremental R2 (full-covars): 0.05716
PGS R2 (no covariates): 0.06672 [0.04387, 0.08956]
age, sex, UKB array type, Genotype PCs
PPM007382 PGS000691
(snpnet.Non_albumin_protein)
PSS006918|
European Ancestry|
21,514 individuals
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
|Ext.
Reported Trait: Non-albumin protein : 0.09985 [0.09278, 0.10691]
Incremental R2 (full-covars): 0.09891
PGS R2 (no covariates): 0.09939 [0.09234, 0.10644]
age, sex, UKB array type, Genotype PCs
PPM007383 PGS000691
(snpnet.Non_albumin_protein)
PSS006919|
South Asian Ancestry|
6,643 individuals
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
|Ext.
Reported Trait: Non-albumin protein : 0.09351 [0.08124, 0.10578]
Incremental R2 (full-covars): 0.08375
PGS R2 (no covariates): 0.08889 [0.07686, 0.10091]
age, sex, UKB array type, Genotype PCs
PPM007384 PGS000691
(snpnet.Non_albumin_protein)
PSS006920|
European Ancestry|
58,191 individuals
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
|Ext.
Reported Trait: Non-albumin protein : 0.10006 [0.09577, 0.10436]
Incremental R2 (full-covars): 0.10006
PGS R2 (no covariates): 0.10018 [0.09588, 0.10448]
age, sex, UKB array type, Genotype PCs
PPM002176 PGS000816
(GRS150_ALT)
PSS001062|
European Ancestry|
3,620 individuals
PGP000201 |
Pazoki R et al. Nat Commun (2021)
Reported Trait: Serum alanine transaminase level OR: 1.72 [1.36, 2.07]
PPM002173 PGS000816
(GRS150_ALT)
PSS001060|
European Ancestry|
331 individuals
PGP000201 |
Pazoki R et al. Nat Commun (2021)
Reported Trait: Serum alanine transaminase level β: 3.09 [2.02, 4.17] Unit of measurement = U/L in alanine transaminase
PPM008163 PGS001081
(GBE_INI23027)
PSS005026|
African Ancestry|
119 individuals
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Reported Trait: JC VP1 antigen for Human Polyomavirus JCV : 0.12869 [0.11349, 0.14388]
Incremental R2 (full-covars): 0.01063
PGS R2 (no covariates): 0.01501 [0.00914, 0.02087]
age, sex, UKB array type, Genotype PCs
PPM008164 PGS001081
(GBE_INI23027)
PSS005027|
East Asian Ancestry|
41 individuals
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Reported Trait: JC VP1 antigen for Human Polyomavirus JCV : 0.29085 [0.2546, 0.32709]
Incremental R2 (full-covars): 0.00221
PGS R2 (no covariates): 0.02124 [0.00772, 0.03476]
age, sex, UKB array type, Genotype PCs
PPM008165 PGS001081
(GBE_INI23027)
PSS005028|
European Ancestry|
471 individuals
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Reported Trait: JC VP1 antigen for Human Polyomavirus JCV : 0.06173 [0.05594, 0.06752]
Incremental R2 (full-covars): 0.03591
PGS R2 (no covariates): 0.03303 [0.02867, 0.0374]
age, sex, UKB array type, Genotype PCs
PPM008166 PGS001081
(GBE_INI23027)
PSS005029|
South Asian Ancestry|
164 individuals
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Reported Trait: JC VP1 antigen for Human Polyomavirus JCV : 0.13865 [0.12444, 0.15285]
Incremental R2 (full-covars): 0.02165
PGS R2 (no covariates): 0.02983 [0.02241, 0.03725]
age, sex, UKB array type, Genotype PCs
PPM008167 PGS001081
(GBE_INI23027)
PSS005030|
European Ancestry|
1,275 individuals
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Reported Trait: JC VP1 antigen for Human Polyomavirus JCV : 0.03787 [0.03505, 0.0407]
Incremental R2 (full-covars): 0.03172
PGS R2 (no covariates): 0.03585 [0.0331, 0.03861]
age, sex, UKB array type, Genotype PCs
PPM008168 PGS001082
(GBE_INI23028)
PSS005031|
African Ancestry|
119 individuals
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Reported Trait: MC VP1 antigen for Merkel Cell Polyomavirus : 0.10713 [0.09292, 0.12133]
Incremental R2 (full-covars): -0.0241
PGS R2 (no covariates): 0.00153 [-0.00037, 0.00343]
age, sex, UKB array type, Genotype PCs
PPM008169 PGS001082
(GBE_INI23028)
PSS005032|
East Asian Ancestry|
41 individuals
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Reported Trait: MC VP1 antigen for Merkel Cell Polyomavirus : 0.39043 [0.35434, 0.42653]
Incremental R2 (full-covars): -0.00937
PGS R2 (no covariates): 0.00795 [-0.00043, 0.01633]
age, sex, UKB array type, Genotype PCs
PPM008170 PGS001082
(GBE_INI23028)
PSS005033|
European Ancestry|
471 individuals
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Reported Trait: MC VP1 antigen for Merkel Cell Polyomavirus : 0.09403 [0.08713, 0.10093]
Incremental R2 (full-covars): 0.06025
PGS R2 (no covariates): 0.08198 [0.07546, 0.08851]
age, sex, UKB array type, Genotype PCs
PPM008171 PGS001082
(GBE_INI23028)
PSS005034|
South Asian Ancestry|
164 individuals
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Reported Trait: MC VP1 antigen for Merkel Cell Polyomavirus : 0.08623 [0.07435, 0.09811]
Incremental R2 (full-covars): 0.01085
PGS R2 (no covariates): 0.00773 [0.00387, 0.0116]
age, sex, UKB array type, Genotype PCs
PPM008172 PGS001082
(GBE_INI23028)
PSS005035|
European Ancestry|
1,275 individuals
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Reported Trait: MC VP1 antigen for Merkel Cell Polyomavirus : 0.05319 [0.04989, 0.05648]
Incremental R2 (full-covars): 0.04747
PGS R2 (no covariates): 0.04937 [0.04618, 0.05256]
age, sex, UKB array type, Genotype PCs
PPM005345 PGS001407
(GBE_INI23022)
PSS005021|
African Ancestry|
119 individuals
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Reported Trait: HTLV-1 gag antigen for Human T-Lymphotropic Virus 1 : 0.18173 [0.16477, 0.19868]
Incremental R2 (full-covars): 0.00586
PGS R2 (no covariates): 0.02091 [0.01403, 0.02779]
age, sex, UKB array type, Genotype PCs
PPM005346 PGS001407
(GBE_INI23022)
PSS005022|
East Asian Ancestry|
41 individuals
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Reported Trait: HTLV-1 gag antigen for Human T-Lymphotropic Virus 1 : 0.22757 [0.19265, 0.26249]
Incremental R2 (full-covars): 0.01155
PGS R2 (no covariates): 0.00849 [-0.00017, 0.01714]
age, sex, UKB array type, Genotype PCs
PPM005347 PGS001407
(GBE_INI23022)
PSS005023|
European Ancestry|
471 individuals
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Reported Trait: HTLV-1 gag antigen for Human T-Lymphotropic Virus 1 : 0.08759 [0.08088, 0.0943]
Incremental R2 (full-covars): 0.02612
PGS R2 (no covariates): 0.03168 [0.0274, 0.03596]
age, sex, UKB array type, Genotype PCs
PPM005348 PGS001407
(GBE_INI23022)
PSS005024|
South Asian Ancestry|
164 individuals
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Reported Trait: HTLV-1 gag antigen for Human T-Lymphotropic Virus 1 Incremental R2 (full-covars): 0.0038
: 0.22286 [0.20661, 0.2391]
PGS R2 (no covariates): 0.01447 [0.00922, 0.01972]
age, sex, UKB array type, Genotype PCs
PPM005349 PGS001407
(GBE_INI23022)
PSS005025|
European Ancestry|
1,275 individuals
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Reported Trait: HTLV-1 gag antigen for Human T-Lymphotropic Virus 1 : 0.03666 [0.03387, 0.03944]
Incremental R2 (full-covars): 0.01644
PGS R2 (no covariates): 0.01753 [0.01557, 0.0195]
age, sex, UKB array type, Genotype PCs
PPM009972 PGS001886
(portability-PLR_albumin)
PSS009382|
European Ancestry|
17,457 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Albumin Partial Correlation (partial-r): 0.2949 [0.2813, 0.3084] sex, age, birth date, deprivation index, 16 PCs
PPM009973 PGS001886
(portability-PLR_albumin)
PSS009156|
European Ancestry|
3,593 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Albumin Partial Correlation (partial-r): 0.2758 [0.2452, 0.3058] sex, age, birth date, deprivation index, 16 PCs
PPM009974 PGS001886
(portability-PLR_albumin)
PSS008710|
European Ancestry|
5,803 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Albumin Partial Correlation (partial-r): 0.2722 [0.2482, 0.2959] sex, age, birth date, deprivation index, 16 PCs
PPM009975 PGS001886
(portability-PLR_albumin)
PSS008484|
Greater Middle Eastern Ancestry|
1,036 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Albumin Partial Correlation (partial-r): 0.2704 [0.2124, 0.3264] sex, age, birth date, deprivation index, 16 PCs
PPM009976 PGS001886
(portability-PLR_albumin)
PSS008262|
South Asian Ancestry|
5,478 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Albumin Partial Correlation (partial-r): 0.2714 [0.2467, 0.2958] sex, age, birth date, deprivation index, 16 PCs
PPM009977 PGS001886
(portability-PLR_albumin)
PSS008040|
East Asian Ancestry|
1,560 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Albumin Partial Correlation (partial-r): 0.226 [0.178, 0.2729] sex, age, birth date, deprivation index, 16 PCs
PPM009978 PGS001886
(portability-PLR_albumin)
PSS007826|
African Ancestry|
2,159 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Albumin Partial Correlation (partial-r): 0.1475 [0.1058, 0.1887] sex, age, birth date, deprivation index, 16 PCs
PPM009979 PGS001886
(portability-PLR_albumin)
PSS008930|
African Ancestry|
3,401 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Albumin Partial Correlation (partial-r): 0.1407 [0.1075, 0.1736] sex, age, birth date, deprivation index, 16 PCs
PPM010396 PGS001940
(portability-PLR_log_ALT)
PSS009201|
European Ancestry|
3,950 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Alanine aminotransferase Partial Correlation (partial-r): 0.2328 [0.203, 0.2622] sex, age, birth date, deprivation index, 16 PCs
PPM010397 PGS001940
(portability-PLR_log_ALT)
PSS008755|
European Ancestry|
6,321 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Alanine aminotransferase Partial Correlation (partial-r): 0.2248 [0.2012, 0.2481] sex, age, birth date, deprivation index, 16 PCs
PPM010399 PGS001940
(portability-PLR_log_ALT)
PSS008307|
South Asian Ancestry|
5,992 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Alanine aminotransferase Partial Correlation (partial-r): 0.2205 [0.1963, 0.2445] sex, age, birth date, deprivation index, 16 PCs
PPM010400 PGS001940
(portability-PLR_log_ALT)
PSS008084|
East Asian Ancestry|
1,716 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Alanine aminotransferase Partial Correlation (partial-r): 0.1841 [0.1377, 0.2297] sex, age, birth date, deprivation index, 16 PCs
PPM010401 PGS001940
(portability-PLR_log_ALT)
PSS007871|
African Ancestry|
2,345 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Alanine aminotransferase Partial Correlation (partial-r): 0.1008 [0.0604, 0.1409] sex, age, birth date, deprivation index, 16 PCs
PPM010402 PGS001940
(portability-PLR_log_ALT)
PSS008975|
African Ancestry|
3,656 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Alanine aminotransferase Partial Correlation (partial-r): 0.1054 [0.0731, 0.1374] sex, age, birth date, deprivation index, 16 PCs
PPM010395 PGS001940
(portability-PLR_log_ALT)
PSS009427|
European Ancestry|
18,995 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Alanine aminotransferase Partial Correlation (partial-r): 0.2633 [0.25, 0.2765] sex, age, birth date, deprivation index, 16 PCs
PPM010398 PGS001940
(portability-PLR_log_ALT)
PSS008529|
Greater Middle Eastern Ancestry|
1,123 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Alanine aminotransferase Partial Correlation (partial-r): 0.1871 [0.1295, 0.2435] sex, age, birth date, deprivation index, 16 PCs
PPM011648 PGS002099
(portability-ldpred2_albumin)
PSS009382|
European Ancestry|
17,457 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Albumin Partial Correlation (partial-r): 0.289 [0.2754, 0.3026] sex, age, birth date, deprivation index, 16 PCs
PPM011649 PGS002099
(portability-ldpred2_albumin)
PSS009156|
European Ancestry|
3,593 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Albumin Partial Correlation (partial-r): 0.2771 [0.2465, 0.3071] sex, age, birth date, deprivation index, 16 PCs
PPM011650 PGS002099
(portability-ldpred2_albumin)
PSS008710|
European Ancestry|
5,803 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Albumin Partial Correlation (partial-r): 0.2717 [0.2476, 0.2954] sex, age, birth date, deprivation index, 16 PCs
PPM011651 PGS002099
(portability-ldpred2_albumin)
PSS008484|
Greater Middle Eastern Ancestry|
1,036 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Albumin Partial Correlation (partial-r): 0.2567 [0.1983, 0.3132] sex, age, birth date, deprivation index, 16 PCs
PPM011652 PGS002099
(portability-ldpred2_albumin)
PSS008262|
South Asian Ancestry|
5,478 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Albumin Partial Correlation (partial-r): 0.265 [0.2402, 0.2895] sex, age, birth date, deprivation index, 16 PCs
PPM011653 PGS002099
(portability-ldpred2_albumin)
PSS008040|
East Asian Ancestry|
1,560 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Albumin Partial Correlation (partial-r): 0.2305 [0.1827, 0.2773] sex, age, birth date, deprivation index, 16 PCs
PPM011654 PGS002099
(portability-ldpred2_albumin)
PSS007826|
African Ancestry|
2,159 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Albumin Partial Correlation (partial-r): 0.1481 [0.1063, 0.1893] sex, age, birth date, deprivation index, 16 PCs
PPM011655 PGS002099
(portability-ldpred2_albumin)
PSS008930|
African Ancestry|
3,401 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Albumin Partial Correlation (partial-r): 0.1569 [0.1238, 0.1896] sex, age, birth date, deprivation index, 16 PCs
PPM012112 PGS002158
(portability-ldpred2_log_ALT)
PSS009201|
European Ancestry|
3,950 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Alanine aminotransferase Partial Correlation (partial-r): 0.2355 [0.2058, 0.2648] sex, age, birth date, deprivation index, 16 PCs
PPM012111 PGS002158
(portability-ldpred2_log_ALT)
PSS009427|
European Ancestry|
18,995 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Alanine aminotransferase Partial Correlation (partial-r): 0.2622 [0.2489, 0.2754] sex, age, birth date, deprivation index, 16 PCs
PPM012113 PGS002158
(portability-ldpred2_log_ALT)
PSS008755|
European Ancestry|
6,321 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Alanine aminotransferase Partial Correlation (partial-r): 0.2258 [0.2022, 0.2491] sex, age, birth date, deprivation index, 16 PCs
PPM012114 PGS002158
(portability-ldpred2_log_ALT)
PSS008529|
Greater Middle Eastern Ancestry|
1,123 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Alanine aminotransferase Partial Correlation (partial-r): 0.1997 [0.1423, 0.2557] sex, age, birth date, deprivation index, 16 PCs
PPM012115 PGS002158
(portability-ldpred2_log_ALT)
PSS008307|
South Asian Ancestry|
5,992 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Alanine aminotransferase Partial Correlation (partial-r): 0.2086 [0.1842, 0.2328] sex, age, birth date, deprivation index, 16 PCs
PPM012116 PGS002158
(portability-ldpred2_log_ALT)
PSS008084|
East Asian Ancestry|
1,716 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Alanine aminotransferase Partial Correlation (partial-r): 0.194 [0.1478, 0.2394] sex, age, birth date, deprivation index, 16 PCs
PPM012117 PGS002158
(portability-ldpred2_log_ALT)
PSS007871|
African Ancestry|
2,345 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Alanine aminotransferase Partial Correlation (partial-r): 0.1063 [0.0659, 0.1463] sex, age, birth date, deprivation index, 16 PCs
PPM012118 PGS002158
(portability-ldpred2_log_ALT)
PSS008975|
African Ancestry|
3,656 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Alanine aminotransferase Partial Correlation (partial-r): 0.088 [0.0557, 0.1202] sex, age, birth date, deprivation index, 16 PCs
PPM014820 PGS002732
(GRS_77)
PSS009901|
Multi-ancestry (including European)|
45,007 individuals
PGP000341 |
Vujkovic M et al. Nat Genet (2022)
Reported Trait: Non-alcoholic fatty liver disease Risk difference: 0.604 [0.418, 0.79] age, gender, 3-5 ancestry PCs
PPM022311 PGS002732
(GRS_77)
PSS011911|
Multi-ancestry (including European)|
48,603 individuals
PGP000701 |
Loesch DP et al. Nat Commun (2025)
|Ext.
Reported Trait: non-alcoholic fattly liver disease OR: 1.31 [1.21, 1.41] age, age^2, sex, UKB centre, array, genetic PCS 1-20
PPM022322 PGS002732
(GRS_77)
PSS011912|
European Ancestry|
45,356 individuals
PGP000701 |
Loesch DP et al. Nat Commun (2025)
|Ext.
Reported Trait: non-alcoholic fattly liver disease OR: 1.31 [1.21, 1.42] age, age^2, sex, UKB centre, array, genetic PCS 1-20
PPM016181 PGS003342
(CVGRS_ALT)
PSS010055|
East Asian Ancestry|
22,608 individuals
PGP000405 |
Kim YJ et al. Nat Commun (2022)
Reported Trait: Alanine aminotransferase level β: 0.1213
PPM016198 PGS003342
(CVGRS_ALT)
PSS010055|
East Asian Ancestry|
22,608 individuals
PGP000405 |
Kim YJ et al. Nat Commun (2022)
Reported Trait: Type 2 diabetes OR: 1.04754
PPM016190 PGS003351
(ALLGRS_ALT)
PSS010055|
East Asian Ancestry|
22,608 individuals
PGP000405 |
Kim YJ et al. Nat Commun (2022)
Reported Trait: Alanine aminotransferase level β: 0.16161
PPM017450 PGS003522
(cont-decay-log_ALT)
PSS010885|
European Ancestry|
19,106 individuals
PGP000457 |
Ding Y et al. bioRxiv (2022)
|Pre
Reported Trait: Alanine aminotransferase partial-R2: 0.07 sex, age, deprivation index, PC1-16
PPM017534 PGS003522
(cont-decay-log_ALT)
PSS010801|
European Ancestry|
3,939 individuals
PGP000457 |
Ding Y et al. bioRxiv (2022)
|Pre
Reported Trait: Alanine aminotransferase partial-R2: 0.05 sex, age, deprivation index, PC1-16
PPM017702 PGS003522
(cont-decay-log_ALT)
PSS010549|
Greater Middle Eastern Ancestry|
1,094 individuals
PGP000457 |
Ding Y et al. bioRxiv (2022)
|Pre
Reported Trait: Alanine aminotransferase partial-R2: 0.04 sex, age, deprivation index, PC1-16
PPM017786 PGS003522
(cont-decay-log_ALT)
PSS010213|
European Ancestry|
2,238 individuals
PGP000457 |
Ding Y et al. bioRxiv (2022)
|Pre
Reported Trait: Alanine aminotransferase partial-R2: 0.07 sex, age, deprivation index, PC1-16
PPM017870 PGS003522
(cont-decay-log_ALT)
PSS010465|
South Asian Ancestry|
5,938 individuals
PGP000457 |
Ding Y et al. bioRxiv (2022)
|Pre
Reported Trait: Alanine aminotransferase partial-R2: 0.04 sex, age, deprivation index, PC1-16
PPM017954 PGS003522
(cont-decay-log_ALT)
PSS010381|
East Asian Ancestry|
1,705 individuals
PGP000457 |
Ding Y et al. bioRxiv (2022)
|Pre
Reported Trait: Alanine aminotransferase partial-R2: 0.03 sex, age, deprivation index, PC1-16
PPM018038 PGS003522
(cont-decay-log_ALT)
PSS010297|
African Ancestry|
2,333 individuals
PGP000457 |
Ding Y et al. bioRxiv (2022)
|Pre
Reported Trait: Alanine aminotransferase partial-R2: 0.01 sex, age, deprivation index, PC1-16
PPM018122 PGS003522
(cont-decay-log_ALT)
PSS010717|
African Ancestry|
3,627 individuals
PGP000457 |
Ding Y et al. bioRxiv (2022)
|Pre
Reported Trait: Alanine aminotransferase partial-R2: 0.01 sex, age, deprivation index, PC1-16
PPM017618 PGS003522
(cont-decay-log_ALT)
PSS010633|
European Ancestry|
6,169 individuals
PGP000457 |
Ding Y et al. bioRxiv (2022)
|Pre
Reported Trait: Alanine aminotransferase partial-R2: 0.05 sex, age, deprivation index, PC1-16
PPM020443 PGS004328
(X30600.score)
PSS011364|
European Ancestry|
56,192 individuals
PGP000561 |
Jung H et al. Commun Biol (2024)
Reported Trait: Albumin PGS R2 (no covariates): 0.18905
PPM020444 PGS004329
(X30620.score)
PSS011364|
European Ancestry|
56,192 individuals
PGP000561 |
Jung H et al. Commun Biol (2024)
Reported Trait: Alanine aminotransferase (U/L) PGS R2 (no covariates): 0.17221
PPM020932 PGS004707
(Albumin_PRSmix_eur)
PSS011480|
European Ancestry|
4,879 individuals
PGP000604 |
Truong B et al. Cell Genom (2024)
Reported Trait: Albumin Incremental R2 (Full model versus model with only covariates): 0.029 [0.019, 0.038] age, sex, PC1, PC2, PC3, PC4, PC5, PC6, PC7, PC8, PC9, PC10 Incremental R2 (Full model versus model with only covariates)
PPM020933 PGS004708
(Albumin_PRSmix_sas)
PSS011460|
South Asian Ancestry|
6,864 individuals
PGP000604 |
Truong B et al. Cell Genom (2024)
Reported Trait: Albumin Incremental R2 (Full model versus model with only covariates): 0.029 [0.021, 0.037] age, sex, PC1, PC2, PC3, PC4, PC5, PC6, PC7, PC8, PC9, PC10 Incremental R2 (Full model versus model with only covariates)
PPM020934 PGS004709
(Albumin_PRSmixPlus_eur)
PSS011480|
European Ancestry|
4,879 individuals
PGP000604 |
Truong B et al. Cell Genom (2024)
Reported Trait: Albumin Incremental R2 (Full model versus model with only covariates): 0.042 [0.031, 0.053] age, sex, PC1, PC2, PC3, PC4, PC5, PC6, PC7, PC8, PC9, PC10 Incremental R2 (Full model versus model with only covariates)
PPM020935 PGS004710
(Albumin_PRSmixPlus_sas)
PSS011460|
South Asian Ancestry|
6,864 individuals
PGP000604 |
Truong B et al. Cell Genom (2024)
Reported Trait: Albumin Incremental R2 (Full model versus model with only covariates): 0.033 [0.025, 0.041] age, sex, PC1, PC2, PC3, PC4, PC5, PC6, PC7, PC8, PC9, PC10 Incremental R2 (Full model versus model with only covariates)
PPM020940 PGS004715
(ALT_PRSmix_eur)
PSS011457|
European Ancestry|
5,247 individuals
PGP000604 |
Truong B et al. Cell Genom (2024)
Reported Trait: Alanine aminotransferase Incremental R2 (Full model versus model with only covariates): 0.013 [0.007, 0.019] age, sex, PC1, PC2, PC3, PC4, PC5, PC6, PC7, PC8, PC9, PC10 Incremental R2 (Full model versus model with only covariates)
PPM020941 PGS004716
(ALT_PRSmix_sas)
PSS011458|
South Asian Ancestry|
6,794 individuals
PGP000604 |
Truong B et al. Cell Genom (2024)
Reported Trait: Alanine aminotransferase Incremental R2 (Full model versus model with only covariates): 0.03 [0.022, 0.038] age, sex, PC1, PC2, PC3, PC4, PC5, PC6, PC7, PC8, PC9, PC10 Incremental R2 (Full model versus model with only covariates)
PPM020942 PGS004717
(ALT_PRSmixPlus_eur)
PSS011457|
European Ancestry|
5,247 individuals
PGP000604 |
Truong B et al. Cell Genom (2024)
Reported Trait: Alanine aminotransferase Incremental R2 (Full model versus model with only covariates): 0.041 [0.03, 0.052] age, sex, PC1, PC2, PC3, PC4, PC5, PC6, PC7, PC8, PC9, PC10 Incremental R2 (Full model versus model with only covariates)
PPM020943 PGS004718
(ALT_PRSmixPlus_sas)
PSS011458|
South Asian Ancestry|
6,794 individuals
PGP000604 |
Truong B et al. Cell Genom (2024)
Reported Trait: Alanine aminotransferase Incremental R2 (Full model versus model with only covariates): 0.031 [0.023, 0.039] age, sex, PC1, PC2, PC3, PC4, PC5, PC6, PC7, PC8, PC9, PC10 Incremental R2 (Full model versus model with only covariates)

Evaluated Samples

PGS Sample Set ID
(PSS)
Phenotype Definitions and Methods Participant Follow-up Time Sample Numbers Age of Study Participants Sample Ancestry Additional Ancestry Description Cohort(s) Additional Sample/Cohort Information
PSS009156 3,593 individuals European Poland (NE Europe) UKB
PSS009201 3,950 individuals European Poland (NE Europe) UKB
PSS000729 5,573 individuals African unspecified UKB
PSS000730 984 individuals East Asian UKB
PSS000731 21,516 individuals European Non-British White UKB
PSS000732 6,687 individuals South Asian UKB
PSS000733 58,196 individuals European
(British)
UKB
PSS010717 3,627 individuals,
46.0 % Male samples
Mean = 51.9 years
Sd = 8.1 years
African unspecified Nigerian UKB
PSS008710 5,803 individuals European Italy (South Europe) UKB
PSS005028 471 individuals European non-white British ancestry UKB
PSS010213 2,238 individuals,
45.0 % Male samples
Mean = 58.1 years
Sd = 7.1 years
European Ashkenazi UKB
PSS011911 ICD10: E11 for T2D, N18 for CKD, first occurence of I20-125 for CAD. BMI: baseline body mass index Median = 14.8 years 48,603 individuals,
46.0 % Male samples
Mean = 56.8 years
Sd = 8.2 years
European, East Asian, South Asian, Hispanic or Latin American, African unspecified UKB
PSS011912 ICD10: E11 for T2D, N18 for CKD, first occurence of I20-125 for CAD, K76.0 for NAFLD. BMI: baseline body mass index Median = 14.8 years 45,356 individuals,
46.0 % Male samples
Mean = 57.1 years
Sd = 8.1 years
European UKB
PSS009901
[
  • 2,829 cases
  • , 41,391 controls
]
European U.S. BioVU, CAP, EPOS PIVENS, FLINT, NASH
PSS009901
[
  • 444 cases
  • , 343 controls
]
Hispanic or Latin American U.S. NR LQTS, NASH
PSS008755 6,321 individuals European Italy (South Europe) UKB
PSS008262 5,478 individuals South Asian India (South Asia) UKB
PSS011457 5,247 individuals European AllofUs
PSS011458 6,794 individuals South Asian G&H
PSS010055 22,608 individuals East Asian KBA, KoGES
PSS011460 6,864 individuals South Asian G&H
PSS010801 3,939 individuals,
38.0 % Male samples
Mean = 54.4 years
Sd = 7.5 years
European Polish UKB
PSS010297 2,333 individuals,
37.0 % Male samples
Mean = 52.5 years
Sd = 8.1 years
African American or Afro-Caribbean Caribbean UKB
PSS011480 4,879 individuals European AllofUs
PSS008307 5,992 individuals South Asian India (South Asia) UKB
PSS006916 5,573 individuals African unspecified UKB
PSS006917 1,436 individuals East Asian UKB
PSS006918 21,514 individuals European non-white British ancestry UKB
PSS006919 6,643 individuals South Asian UKB
PSS006920 58,191 individuals European white British ancestry UKB Testing cohort (heldout set)
PSS007826 2,159 individuals African American or Afro-Caribbean Carribean UKB
PSS009382 17,457 individuals European UK (+ Ireland) UKB
PSS010885 19,106 individuals,
46.0 % Male samples
Mean = 56.9 years
Sd = 7.9 years
European white British UKB
PSS010381 1,705 individuals,
33.0 % Male samples
Mean = 52.4 years
Sd = 7.8 years
East Asian Chinese UKB
PSS007871 2,345 individuals African American or Afro-Caribbean Carribean UKB
PSS009427 18,995 individuals European UK (+ Ireland) UKB
PSS008930 3,401 individuals African unspecified Nigeria (West Africa) UKB
PSS010465 5,938 individuals,
54.0 % Male samples
Mean = 53.3 years
Sd = 8.4 years
South Asian Indian UKB
PSS008975 3,656 individuals African unspecified Nigeria (West Africa) UKB
PSS011364 56,192 individuals European UKB
PSS007066 5,658 individuals African unspecified UKB
PSS007067 1,472 individuals East Asian UKB
PSS008484 1,036 individuals Greater Middle Eastern (Middle Eastern, North African or Persian) Iran (Middle East) UKB
PSS007068 21,759 individuals European non-white British ancestry UKB
PSS000364 4,678 individuals European
(Swedish)
MDC
PSS005023 471 individuals European non-white British ancestry UKB
PSS005024 164 individuals South Asian UKB
PSS005025 1,275 individuals European white British ancestry UKB Testing cohort (heldout set)
PSS007070 59,097 individuals European white British ancestry UKB Testing cohort (heldout set)
PSS007069 6,786 individuals South Asian UKB
PSS005021 119 individuals African unspecified UKB
PSS005022 41 individuals East Asian UKB
PSS005026 119 individuals African unspecified UKB
PSS005027 41 individuals East Asian UKB
PSS007076 6,099 individuals African unspecified UKB
PSS007077 1,615 individuals East Asian UKB
PSS007078 23,758 individuals European non-white British ancestry UKB
PSS007079 7,414 individuals South Asian UKB
PSS007080 64,440 individuals European white British ancestry UKB Testing cohort (heldout set)
PSS001062 Serum concentrations of alanine transaminase (ALT), alkaline phosphatase (ALP), and gamma-glutamyl transferase (GGT) were measured from stored blood samples using the enzymatic rate analytical method on a Beckman Coulter AU5800. The manufacturer’s analytic range for ALT was 3–500 U/L, for ALP, 5–1500 U/L, and it was 5–1200 U/L for GGT. 3,620 individuals European NFBC
PSS005029 164 individuals South Asian UKB
PSS005030 1,275 individuals European white British ancestry UKB Testing cohort (heldout set)
PSS005031 119 individuals African unspecified UKB
PSS005032 41 individuals East Asian UKB
PSS005033 471 individuals European non-white British ancestry UKB
PSS005034 164 individuals South Asian UKB
PSS005035 1,275 individuals European white British ancestry UKB Testing cohort (heldout set)
PSS008529 1,123 individuals Greater Middle Eastern (Middle Eastern, North African or Persian) Iran (Middle East) UKB
PSS010549 1,094 individuals,
60.0 % Male samples
Mean = 51.9 years
Sd = 7.9 years
Greater Middle Eastern (Middle Eastern, North African or Persian) Iranian UKB
PSS008040 1,560 individuals East Asian China (East Asia) UKB
PSS001060 Serum concentrations of alanine transaminase (ALT) and alkaline phosphatase (ALP), were measured from stored blood samples using the enzymatic rate analytical method on a Beckman Coulter AU5800. The manufacturer’s analytic range for ALT was 3–500 U/L, for ALP, 5–1500 U/L, and it was 5–1200 U/L for GGT. 331 individuals European Airwave
PSS000622 6,017 individuals African unspecified UKB
PSS000623 1,081 individuals East Asian UKB
PSS000624 23,569 individuals European Non-British White UKB
PSS000625 7,325 individuals South Asian UKB
PSS000626 63,766 individuals European
(British)
UKB
PSS000627 5,573 individuals African unspecified UKB
PSS000628 984 individuals East Asian UKB
PSS000629 21,516 individuals European Non-British White UKB
PSS000630 6,687 individuals South Asian UKB
PSS000631 58,196 individuals European
(British)
UKB
PSS008084 1,716 individuals East Asian China (East Asia) UKB
PSS010633 6,169 individuals,
45.0 % Male samples
Mean = 54.5 years
Sd = 8.4 years
European Italian UKB