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PGS Catalog
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Polygenic Scores (PGS)
Polygenic Scores (PGS)
Filter PGS by Participant Ancestry
Individuals included in:
Any Stage [G, D, E]
All Stages combined [G + D + E]
Development [G, D]
- GWAS [G]
- Score development [D]
PGS Evaluation [E]
G
- Source of Variant Associations (
G
WAS)
D
- Score
D
evelopment/Training
E
- PGS
E
valuation
List of ancestries includes:
--
African
East Asian
South Asian
Additional Asian Ancestries
European
Greater Middle Eastern
Hispanic or Latin American
Additional Diverse Ancestries
Not Reported
Display options:
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Multi-ancestry data
Ancestry legend
Multi-ancestry (including European)
Multi-ancestry (excluding European)
African
East Asian
South Asian
Additional Asian Ancestries
European
Greater Middle Eastern
Hispanic or Latin American
Additional Diverse Ancestries
Not Reported
Polygenic Score ID & Name
PGS Publication ID
(PGP)
Reported Trait
Mapped Trait(s)
(Ontology)
Number of Variants
Ancestry distribution
GWAS
Dev
Eval
Scoring File
(FTP Link)
PGS018669
(TPMI_242_PRSmix+)
PGP000835
|
Chen HH
et al.
Nature (2025)
Thyrotoxicosis with or without goiter
thyrotoxicosis
1,071,402
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018669/ScoringFiles/PGS018669.txt.gz
PGS018670
(TPMI_242_SBayesR)
PGP000835
|
Chen HH
et al.
Nature (2025)
Thyrotoxicosis with or without goiter
thyrotoxicosis
151,393
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018670/ScoringFiles/PGS018670.txt.gz
PGS018671
(TPMI_242.1_Lassosum2)
PGP000835
|
Chen HH
et al.
Nature (2025)
Graves disease
Graves disease
415
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018671/ScoringFiles/PGS018671.txt.gz
PGS018672
(TPMI_242.1_LDpred2)
PGP000835
|
Chen HH
et al.
Nature (2025)
Graves disease
Graves disease
220,843
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018672/ScoringFiles/PGS018672.txt.gz
PGS018673
(TPMI_242.1_MegaPRS)
PGP000835
|
Chen HH
et al.
Nature (2025)
Graves disease
Graves disease
37,771
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018673/ScoringFiles/PGS018673.txt.gz
PGS018674
(TPMI_242.1_PRS-CS)
PGP000835
|
Chen HH
et al.
Nature (2025)
Graves disease
Graves disease
983,772
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018674/ScoringFiles/PGS018674.txt.gz
PGS018675
(TPMI_242.1_PRSmix+)
PGP000835
|
Chen HH
et al.
Nature (2025)
Graves disease
Graves disease
1,071,402
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018675/ScoringFiles/PGS018675.txt.gz
PGS018676
(TPMI_242.1_SBayesR)
PGP000835
|
Chen HH
et al.
Nature (2025)
Graves disease
Graves disease
975,251
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018676/ScoringFiles/PGS018676.txt.gz
PGS018677
(TPMI_244_Lassosum2)
PGP000835
|
Chen HH
et al.
Nature (2025)
Hypothyroidism
hypothyroidism
217
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018677/ScoringFiles/PGS018677.txt.gz
PGS018678
(TPMI_244_LDpred2)
PGP000835
|
Chen HH
et al.
Nature (2025)
Hypothyroidism
hypothyroidism
939,824
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018678/ScoringFiles/PGS018678.txt.gz
PGS018679
(TPMI_244_MegaPRS)
PGP000835
|
Chen HH
et al.
Nature (2025)
Hypothyroidism
hypothyroidism
24,819
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018679/ScoringFiles/PGS018679.txt.gz
PGS018680
(TPMI_244_PRS-CS)
PGP000835
|
Chen HH
et al.
Nature (2025)
Hypothyroidism
hypothyroidism
983,780
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018680/ScoringFiles/PGS018680.txt.gz
PGS018681
(TPMI_244_PRSmix+)
PGP000835
|
Chen HH
et al.
Nature (2025)
Hypothyroidism
hypothyroidism
1,071,402
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018681/ScoringFiles/PGS018681.txt.gz
PGS018682
(TPMI_244_SBayesR)
PGP000835
|
Chen HH
et al.
Nature (2025)
Hypothyroidism
hypothyroidism
966,339
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018682/ScoringFiles/PGS018682.txt.gz
PGS018683
(TPMI_244.4_Lassosum2)
PGP000835
|
Chen HH
et al.
Nature (2025)
Hypothyroidism NOS
hypothyroidism
493
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018683/ScoringFiles/PGS018683.txt.gz
PGS018684
(TPMI_244.4_LDpred2)
PGP000835
|
Chen HH
et al.
Nature (2025)
Hypothyroidism NOS
hypothyroidism
939,822
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018684/ScoringFiles/PGS018684.txt.gz
PGS018685
(TPMI_244.4_MegaPRS)
PGP000835
|
Chen HH
et al.
Nature (2025)
Hypothyroidism NOS
hypothyroidism
414,367
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018685/ScoringFiles/PGS018685.txt.gz
PGS018686
(TPMI_244.4_PRS-CS)
PGP000835
|
Chen HH
et al.
Nature (2025)
Hypothyroidism NOS
hypothyroidism
983,778
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018686/ScoringFiles/PGS018686.txt.gz
PGS018687
(TPMI_244.4_PRSmix+)
PGP000835
|
Chen HH
et al.
Nature (2025)
Hypothyroidism NOS
hypothyroidism
1,071,403
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018687/ScoringFiles/PGS018687.txt.gz
PGS018688
(TPMI_244.4_SBayesR)
PGP000835
|
Chen HH
et al.
Nature (2025)
Hypothyroidism NOS
hypothyroidism
951,538
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018688/ScoringFiles/PGS018688.txt.gz
PGS018689
(TPMI_245_Lassosum2)
PGP000835
|
Chen HH
et al.
Nature (2025)
Thyroiditis
thyroiditis
2,574
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018689/ScoringFiles/PGS018689.txt.gz
PGS018690
(TPMI_245_LDpred2)
PGP000835
|
Chen HH
et al.
Nature (2025)
Thyroiditis
thyroiditis
939,823
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018690/ScoringFiles/PGS018690.txt.gz
PGS018691
(TPMI_245_MegaPRS)
PGP000835
|
Chen HH
et al.
Nature (2025)
Thyroiditis
thyroiditis
38,746
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018691/ScoringFiles/PGS018691.txt.gz
PGS018692
(TPMI_245_PRS-CS)
PGP000835
|
Chen HH
et al.
Nature (2025)
Thyroiditis
thyroiditis
983,779
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018692/ScoringFiles/PGS018692.txt.gz
PGS018693
(TPMI_245_PRSmix+)
PGP000835
|
Chen HH
et al.
Nature (2025)
Thyroiditis
thyroiditis
1,071,402
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018693/ScoringFiles/PGS018693.txt.gz
PGS018694
(TPMI_245_SBayesR)
PGP000835
|
Chen HH
et al.
Nature (2025)
Thyroiditis
thyroiditis
976,726
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018694/ScoringFiles/PGS018694.txt.gz
PGS018695
(TPMI_245.2_Lassosum2)
PGP000835
|
Chen HH
et al.
Nature (2025)
Chronic thyroiditis
Hashimoto thyroiditis
171
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018695/ScoringFiles/PGS018695.txt.gz
PGS018696
(TPMI_245.2_LDpred2)
PGP000835
|
Chen HH
et al.
Nature (2025)
Chronic thyroiditis
Hashimoto thyroiditis
939,816
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018696/ScoringFiles/PGS018696.txt.gz
PGS018697
(TPMI_245.2_MegaPRS)
PGP000835
|
Chen HH
et al.
Nature (2025)
Chronic thyroiditis
Hashimoto thyroiditis
392,668
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018697/ScoringFiles/PGS018697.txt.gz
PGS018698
(TPMI_245.2_PRS-CS)
PGP000835
|
Chen HH
et al.
Nature (2025)
Chronic thyroiditis
Hashimoto thyroiditis
983,771
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018698/ScoringFiles/PGS018698.txt.gz
PGS018699
(TPMI_245.2_PRSmix+)
PGP000835
|
Chen HH
et al.
Nature (2025)
Chronic thyroiditis
Hashimoto thyroiditis
1,071,404
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018699/ScoringFiles/PGS018699.txt.gz
PGS018700
(TPMI_245.2_SBayesR)
PGP000835
|
Chen HH
et al.
Nature (2025)
Chronic thyroiditis
Hashimoto thyroiditis
979,446
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018700/ScoringFiles/PGS018700.txt.gz
PGS018701
(TPMI_245.21_Lassosum2)
PGP000835
|
Chen HH
et al.
Nature (2025)
Chronic lymphocytic thyroiditis
Hashimoto thyroiditis
190
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018701/ScoringFiles/PGS018701.txt.gz
PGS018702
(TPMI_245.21_LDpred2)
PGP000835
|
Chen HH
et al.
Nature (2025)
Chronic lymphocytic thyroiditis
Hashimoto thyroiditis
318,664
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018702/ScoringFiles/PGS018702.txt.gz
PGS018703
(TPMI_245.21_MegaPRS)
PGP000835
|
Chen HH
et al.
Nature (2025)
Chronic lymphocytic thyroiditis
Hashimoto thyroiditis
394,827
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018703/ScoringFiles/PGS018703.txt.gz
PGS018704
(TPMI_245.21_PRS-CS)
PGP000835
|
Chen HH
et al.
Nature (2025)
Chronic lymphocytic thyroiditis
Hashimoto thyroiditis
983,771
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018704/ScoringFiles/PGS018704.txt.gz
PGS018705
(TPMI_245.21_PRSmix+)
PGP000835
|
Chen HH
et al.
Nature (2025)
Chronic lymphocytic thyroiditis
Hashimoto thyroiditis
1,071,405
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018705/ScoringFiles/PGS018705.txt.gz
PGS018706
(TPMI_245.21_SBayesR)
PGP000835
|
Chen HH
et al.
Nature (2025)
Chronic lymphocytic thyroiditis
Hashimoto thyroiditis
1,005,256
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018706/ScoringFiles/PGS018706.txt.gz
PGS018707
(TPMI_246_Lassosum2)
PGP000835
|
Chen HH
et al.
Nature (2025)
Other disorders of thyroid
thyroid gland disorder
3,470
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018707/ScoringFiles/PGS018707.txt.gz
PGS018708
(TPMI_246_LDpred2)
PGP000835
|
Chen HH
et al.
Nature (2025)
Other disorders of thyroid
thyroid gland disorder
939,875
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018708/ScoringFiles/PGS018708.txt.gz
PGS018709
(TPMI_246_MegaPRS)
PGP000835
|
Chen HH
et al.
Nature (2025)
Other disorders of thyroid
thyroid gland disorder
23,611
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018709/ScoringFiles/PGS018709.txt.gz
PGS018710
(TPMI_246_PRS-CS)
PGP000835
|
Chen HH
et al.
Nature (2025)
Other disorders of thyroid
thyroid gland disorder
983,821
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018710/ScoringFiles/PGS018710.txt.gz
PGS018711
(TPMI_246_SBayesR)
PGP000835
|
Chen HH
et al.
Nature (2025)
Other disorders of thyroid
thyroid gland disorder
967,487
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018711/ScoringFiles/PGS018711.txt.gz
PGS018712
(TPMI_246.2_Lassosum2)
PGP000835
|
Chen HH
et al.
Nature (2025)
Thyroid cyst
dermoid cyst
287
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018712/ScoringFiles/PGS018712.txt.gz
PGS018713
(TPMI_246.2_LDpred2)
PGP000835
|
Chen HH
et al.
Nature (2025)
Thyroid cyst
dermoid cyst
237,092
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018713/ScoringFiles/PGS018713.txt.gz
PGS018714
(TPMI_246.2_MegaPRS)
PGP000835
|
Chen HH
et al.
Nature (2025)
Thyroid cyst
dermoid cyst
552,969
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018714/ScoringFiles/PGS018714.txt.gz
PGS018715
(TPMI_246.2_PRS-CS)
PGP000835
|
Chen HH
et al.
Nature (2025)
Thyroid cyst
dermoid cyst
983,778
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018715/ScoringFiles/PGS018715.txt.gz
PGS018716
(TPMI_246.2_SBayesR)
PGP000835
|
Chen HH
et al.
Nature (2025)
Thyroid cyst
dermoid cyst
1,016,561
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018716/ScoringFiles/PGS018716.txt.gz
PGS018717
(TPMI_250_Lassosum2)
PGP000835
|
Chen HH
et al.
Nature (2025)
Diabetes mellitus
diabetes mellitus
47,432
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018717/ScoringFiles/PGS018717.txt.gz
PGS018718
(TPMI_250_LDpred2)
PGP000835
|
Chen HH
et al.
Nature (2025)
Diabetes mellitus
diabetes mellitus
939,825
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018718/ScoringFiles/PGS018718.txt.gz
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