Polygenic Scores (PGS)

Filter PGS by Participant Ancestry
Individuals included in:
G - Source of Variant Associations (GWAS)
D - Score Development/Training
E - PGS Evaluation
List of ancestries includes:
Display options:
Ancestry legend
Multi-ancestry (including European)
Multi-ancestry (excluding European)
African
East Asian
South Asian
Additional Asian Ancestries
European
Greater Middle Eastern
Hispanic or Latin American
Additional Diverse Ancestries
Not Reported
Polygenic Score ID & Name PGS Publication ID (PGP) Reported Trait Mapped Trait(s) (Ontology) Number of Variants Ancestry distribution
GWAS
Dev
Eval
Scoring File (FTP Link)
PGS018769
(TPMI_250.24_SBayesR)
PGP000835 |
Chen HH et al. Nature (2025)
Type 2 diabetes with neurological manifestations type 2 diabetes mellitus 954,026
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018769/ScoringFiles/PGS018769.txt.gz
PGS018770
(TPMI_250.25_Lassosum2)
PGP000835 |
Chen HH et al. Nature (2025)
Diabetes type 2 with peripheral circulatory disorders type 2 diabetes mellitus 5,553
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018770/ScoringFiles/PGS018770.txt.gz
PGS018771
(TPMI_250.25_LDpred2)
PGP000835 |
Chen HH et al. Nature (2025)
Diabetes type 2 with peripheral circulatory disorders type 2 diabetes mellitus 939,817
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018771/ScoringFiles/PGS018771.txt.gz
PGS018772
(TPMI_250.25_MegaPRS)
PGP000835 |
Chen HH et al. Nature (2025)
Diabetes type 2 with peripheral circulatory disorders type 2 diabetes mellitus 208,439
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018772/ScoringFiles/PGS018772.txt.gz
PGS018773
(TPMI_250.25_PRS-CS)
PGP000835 |
Chen HH et al. Nature (2025)
Diabetes type 2 with peripheral circulatory disorders type 2 diabetes mellitus 983,770
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018773/ScoringFiles/PGS018773.txt.gz
PGS018774
(TPMI_250.25_PRSmix+)
PGP000835 |
Chen HH et al. Nature (2025)
Diabetes type 2 with peripheral circulatory disorders type 2 diabetes mellitus 1,071,475
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018774/ScoringFiles/PGS018774.txt.gz
PGS018775
(TPMI_250.25_SBayesR)
PGP000835 |
Chen HH et al. Nature (2025)
Diabetes type 2 with peripheral circulatory disorders type 2 diabetes mellitus 1,031,761
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018775/ScoringFiles/PGS018775.txt.gz
PGS018776
(TPMI_250.41_Lassosum2)
PGP000835 |
Chen HH et al. Nature (2025)
Impaired fasting glucose Impaired glucose tolerance 785,857
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018776/ScoringFiles/PGS018776.txt.gz
PGS018777
(TPMI_250.41_LDpred2)
PGP000835 |
Chen HH et al. Nature (2025)
Impaired fasting glucose Impaired glucose tolerance 939,845
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018777/ScoringFiles/PGS018777.txt.gz
PGS018778
(TPMI_250.41_MegaPRS)
PGP000835 |
Chen HH et al. Nature (2025)
Impaired fasting glucose Impaired glucose tolerance 37,695
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018778/ScoringFiles/PGS018778.txt.gz
PGS018779
(TPMI_250.41_PRS-CS)
PGP000835 |
Chen HH et al. Nature (2025)
Impaired fasting glucose Impaired glucose tolerance 983,789
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018779/ScoringFiles/PGS018779.txt.gz
PGS018780
(TPMI_250.41_SBayesR)
PGP000835 |
Chen HH et al. Nature (2025)
Impaired fasting glucose Impaired glucose tolerance 969,948
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018780/ScoringFiles/PGS018780.txt.gz
PGS018781
(TPMI_251_Lassosum2)
PGP000835 |
Chen HH et al. Nature (2025)
Other disorders of pancreatic internal secretion metabolic disease 51,658
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018781/ScoringFiles/PGS018781.txt.gz
PGS018782
(TPMI_251_LDpred2)
PGP000835 |
Chen HH et al. Nature (2025)
Other disorders of pancreatic internal secretion metabolic disease 939,892
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018782/ScoringFiles/PGS018782.txt.gz
PGS018783
(TPMI_251_MegaPRS)
PGP000835 |
Chen HH et al. Nature (2025)
Other disorders of pancreatic internal secretion metabolic disease 32,159
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018783/ScoringFiles/PGS018783.txt.gz
PGS018784
(TPMI_251_PRS-CS)
PGP000835 |
Chen HH et al. Nature (2025)
Other disorders of pancreatic internal secretion metabolic disease 983,827
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018784/ScoringFiles/PGS018784.txt.gz
PGS018785
(TPMI_251_SBayesR)
PGP000835 |
Chen HH et al. Nature (2025)
Other disorders of pancreatic internal secretion metabolic disease 902,148
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018785/ScoringFiles/PGS018785.txt.gz
PGS018786
(TPMI_272_Lassosum2)
PGP000835 |
Chen HH et al. Nature (2025)
Disorders of lipoid metabolism metabolic disease 2,898
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018786/ScoringFiles/PGS018786.txt.gz
PGS018787
(TPMI_272_LDpred2)
PGP000835 |
Chen HH et al. Nature (2025)
Disorders of lipoid metabolism metabolic disease 939,823
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018787/ScoringFiles/PGS018787.txt.gz
PGS018788
(TPMI_272_MegaPRS)
PGP000835 |
Chen HH et al. Nature (2025)
Disorders of lipoid metabolism metabolic disease 607,470
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018788/ScoringFiles/PGS018788.txt.gz
PGS018789
(TPMI_272_PRS-CS)
PGP000835 |
Chen HH et al. Nature (2025)
Disorders of lipoid metabolism metabolic disease 983,777
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018789/ScoringFiles/PGS018789.txt.gz
PGS018790
(TPMI_272_SBayesR)
PGP000835 |
Chen HH et al. Nature (2025)
Disorders of lipoid metabolism metabolic disease 50,658
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018790/ScoringFiles/PGS018790.txt.gz
PGS018791
(TPMI_272.1_Lassosum2)
PGP000835 |
Chen HH et al. Nature (2025)
Hyperlipidemia hyperlipidemia 2,990
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018791/ScoringFiles/PGS018791.txt.gz
PGS018792
(TPMI_272.1_LDpred2)
PGP000835 |
Chen HH et al. Nature (2025)
Hyperlipidemia hyperlipidemia 939,817
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018792/ScoringFiles/PGS018792.txt.gz
PGS018793
(TPMI_272.1_MegaPRS)
PGP000835 |
Chen HH et al. Nature (2025)
Hyperlipidemia hyperlipidemia 620,040
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018793/ScoringFiles/PGS018793.txt.gz
PGS018794
(TPMI_272.1_PRS-CS)
PGP000835 |
Chen HH et al. Nature (2025)
Hyperlipidemia hyperlipidemia 983,772
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018794/ScoringFiles/PGS018794.txt.gz
PGS018795
(TPMI_272.1_SBayesR)
PGP000835 |
Chen HH et al. Nature (2025)
Hyperlipidemia hyperlipidemia 64,248
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018795/ScoringFiles/PGS018795.txt.gz
PGS018796
(TPMI_272.9_Lassosum2)
PGP000835 |
Chen HH et al. Nature (2025)
Unspecified disorder of lipoid metabolism inherited lipid metabolism disorder 3,795
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018796/ScoringFiles/PGS018796.txt.gz
PGS018797
(TPMI_272.9_LDpred2)
PGP000835 |
Chen HH et al. Nature (2025)
Unspecified disorder of lipoid metabolism inherited lipid metabolism disorder 939,861
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018797/ScoringFiles/PGS018797.txt.gz
PGS018798
(TPMI_272.9_MegaPRS)
PGP000835 |
Chen HH et al. Nature (2025)
Unspecified disorder of lipoid metabolism inherited lipid metabolism disorder 424,842
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018798/ScoringFiles/PGS018798.txt.gz
PGS018799
(TPMI_272.9_PRS-CS)
PGP000835 |
Chen HH et al. Nature (2025)
Unspecified disorder of lipoid metabolism inherited lipid metabolism disorder 983,798
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018799/ScoringFiles/PGS018799.txt.gz
PGS018800
(TPMI_272.9_SBayesR)
PGP000835 |
Chen HH et al. Nature (2025)
Unspecified disorder of lipoid metabolism inherited lipid metabolism disorder 32,732
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018800/ScoringFiles/PGS018800.txt.gz
PGS018801
(TPMI_272.11_Lassosum2)
PGP000835 |
Chen HH et al. Nature (2025)
Hypercholesterolemia Hypercholesterolemia 63
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018801/ScoringFiles/PGS018801.txt.gz
PGS018802
(TPMI_272.11_LDpred2)
PGP000835 |
Chen HH et al. Nature (2025)
Hypercholesterolemia Hypercholesterolemia 939,847
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018802/ScoringFiles/PGS018802.txt.gz
PGS018803
(TPMI_272.11_MegaPRS)
PGP000835 |
Chen HH et al. Nature (2025)
Hypercholesterolemia Hypercholesterolemia 30,252
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018803/ScoringFiles/PGS018803.txt.gz
PGS018804
(TPMI_272.11_PRS-CS)
PGP000835 |
Chen HH et al. Nature (2025)
Hypercholesterolemia Hypercholesterolemia 983,789
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018804/ScoringFiles/PGS018804.txt.gz
PGS018805
(TPMI_272.11_SBayesR)
PGP000835 |
Chen HH et al. Nature (2025)
Hypercholesterolemia Hypercholesterolemia 97,362
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018805/ScoringFiles/PGS018805.txt.gz
PGS018806
(TPMI_272.12_Lassosum2)
PGP000835 |
Chen HH et al. Nature (2025)
Hyperglyceridemia familial lipoprotein lipase deficiency 26
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018806/ScoringFiles/PGS018806.txt.gz
PGS018807
(TPMI_272.12_LDpred2)
PGP000835 |
Chen HH et al. Nature (2025)
Hyperglyceridemia familial lipoprotein lipase deficiency 939,771
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018807/ScoringFiles/PGS018807.txt.gz
PGS018808
(TPMI_272.12_MegaPRS)
PGP000835 |
Chen HH et al. Nature (2025)
Hyperglyceridemia familial lipoprotein lipase deficiency 509,844
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018808/ScoringFiles/PGS018808.txt.gz
PGS018809
(TPMI_272.12_PRS-CS)
PGP000835 |
Chen HH et al. Nature (2025)
Hyperglyceridemia familial lipoprotein lipase deficiency 983,736
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018809/ScoringFiles/PGS018809.txt.gz
PGS018810
(TPMI_272.12_SBayesR)
PGP000835 |
Chen HH et al. Nature (2025)
Hyperglyceridemia familial lipoprotein lipase deficiency 26,876
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018810/ScoringFiles/PGS018810.txt.gz
PGS018811
(TPMI_272.13_Lassosum2)
PGP000835 |
Chen HH et al. Nature (2025)
Mixed hyperlipidemia hyperlipidemia 594
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018811/ScoringFiles/PGS018811.txt.gz
PGS018812
(TPMI_272.13_LDpred2)
PGP000835 |
Chen HH et al. Nature (2025)
Mixed hyperlipidemia hyperlipidemia 939,841
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018812/ScoringFiles/PGS018812.txt.gz
PGS018813
(TPMI_272.13_MegaPRS)
PGP000835 |
Chen HH et al. Nature (2025)
Mixed hyperlipidemia hyperlipidemia 43,897
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018813/ScoringFiles/PGS018813.txt.gz
PGS018814
(TPMI_272.13_PRS-CS)
PGP000835 |
Chen HH et al. Nature (2025)
Mixed hyperlipidemia hyperlipidemia 983,790
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018814/ScoringFiles/PGS018814.txt.gz
PGS018815
(TPMI_272.13_SBayesR)
PGP000835 |
Chen HH et al. Nature (2025)
Mixed hyperlipidemia hyperlipidemia 62,199
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018815/ScoringFiles/PGS018815.txt.gz
PGS018816
(TPMI_274_Lassosum2)
PGP000835 |
Chen HH et al. Nature (2025)
Gout and other crystal arthropathies chondrocalcinosis 2 7,370
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018816/ScoringFiles/PGS018816.txt.gz
PGS018817
(TPMI_274_LDpred2)
PGP000835 |
Chen HH et al. Nature (2025)
Gout and other crystal arthropathies chondrocalcinosis 2 939,841
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018817/ScoringFiles/PGS018817.txt.gz
PGS018818
(TPMI_274_MegaPRS)
PGP000835 |
Chen HH et al. Nature (2025)
Gout and other crystal arthropathies chondrocalcinosis 2 483,537
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018818/ScoringFiles/PGS018818.txt.gz