Polygenic Scores (PGS)

Filter PGS by Participant Ancestry
Individuals included in:
G - Source of Variant Associations (GWAS)
D - Score Development/Training
E - PGS Evaluation
List of ancestries includes:
Display options:
Ancestry legend
Multi-ancestry (including European)
Multi-ancestry (excluding European)
African
East Asian
South Asian
Additional Asian Ancestries
European
Greater Middle Eastern
Hispanic or Latin American
Additional Diverse Ancestries
Not Reported
Polygenic Score ID & Name PGS Publication ID (PGP) Reported Trait Mapped Trait(s) (Ontology) Number of Variants Ancestry distribution
GWAS
Dev
Eval
 Scoring File (FTP Link)
PGS018708
(TPMI_246_LDpred2)
 PGP000835 |
Chen HH et al. Nature (2025)
 Other disorders of thyroid thyroid gland disorder 939,875
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018708/ScoringFiles/PGS018708.txt.gz
PGS018709
(TPMI_246_MegaPRS)
 PGP000835 |
Chen HH et al. Nature (2025)
 Other disorders of thyroid thyroid gland disorder 23,611
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018709/ScoringFiles/PGS018709.txt.gz
PGS018710
(TPMI_246_PRS-CS)
 PGP000835 |
Chen HH et al. Nature (2025)
 Other disorders of thyroid thyroid gland disorder 983,821
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018710/ScoringFiles/PGS018710.txt.gz
PGS018711
(TPMI_246_SBayesR)
 PGP000835 |
Chen HH et al. Nature (2025)
 Other disorders of thyroid thyroid gland disorder 967,487
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018711/ScoringFiles/PGS018711.txt.gz
PGS018712
(TPMI_246.2_Lassosum2)
 PGP000835 |
Chen HH et al. Nature (2025)
 Thyroid cyst dermoid cyst 287
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018712/ScoringFiles/PGS018712.txt.gz
PGS018713
(TPMI_246.2_LDpred2)
 PGP000835 |
Chen HH et al. Nature (2025)
 Thyroid cyst dermoid cyst 237,092
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018713/ScoringFiles/PGS018713.txt.gz
PGS018714
(TPMI_246.2_MegaPRS)
 PGP000835 |
Chen HH et al. Nature (2025)
 Thyroid cyst dermoid cyst 552,969
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018714/ScoringFiles/PGS018714.txt.gz
PGS018715
(TPMI_246.2_PRS-CS)
 PGP000835 |
Chen HH et al. Nature (2025)
 Thyroid cyst dermoid cyst 983,778
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018715/ScoringFiles/PGS018715.txt.gz
PGS018716
(TPMI_246.2_SBayesR)
 PGP000835 |
Chen HH et al. Nature (2025)
 Thyroid cyst dermoid cyst 1,016,561
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018716/ScoringFiles/PGS018716.txt.gz
PGS018717
(TPMI_250_Lassosum2)
 PGP000835 |
Chen HH et al. Nature (2025)
 Diabetes mellitus diabetes mellitus 47,432
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018717/ScoringFiles/PGS018717.txt.gz
PGS018718
(TPMI_250_LDpred2)
 PGP000835 |
Chen HH et al. Nature (2025)
 Diabetes mellitus diabetes mellitus 939,825
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018718/ScoringFiles/PGS018718.txt.gz
PGS018719
(TPMI_250_MegaPRS)
 PGP000835 |
Chen HH et al. Nature (2025)
 Diabetes mellitus diabetes mellitus 309,556
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018719/ScoringFiles/PGS018719.txt.gz
PGS018720
(TPMI_250_PRS-CS)
 PGP000835 |
Chen HH et al. Nature (2025)
 Diabetes mellitus diabetes mellitus 983,776
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018720/ScoringFiles/PGS018720.txt.gz
PGS018721
(TPMI_250_PRSmix+)
 PGP000835 |
Chen HH et al. Nature (2025)
 Diabetes mellitus diabetes mellitus 1,071,472
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018721/ScoringFiles/PGS018721.txt.gz
PGS018722
(TPMI_250_SBayesR)
 PGP000835 |
Chen HH et al. Nature (2025)
 Diabetes mellitus diabetes mellitus 802,669
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018722/ScoringFiles/PGS018722.txt.gz
PGS018723
(TPMI_250.2_Lassosum2)
 PGP000835 |
Chen HH et al. Nature (2025)
 Type 2 diabetes (T2D) type 2 diabetes mellitus 49,618
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018723/ScoringFiles/PGS018723.txt.gz
PGS018724
(TPMI_250.2_LDpred2)
 PGP000835 |
Chen HH et al. Nature (2025)
 Type 2 diabetes (T2D) type 2 diabetes mellitus 939,826
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018724/ScoringFiles/PGS018724.txt.gz
PGS018725
(TPMI_250.2_MegaPRS)
 PGP000835 |
Chen HH et al. Nature (2025)
 Type 2 diabetes (T2D) type 2 diabetes mellitus 687,652
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018725/ScoringFiles/PGS018725.txt.gz
PGS018726
(TPMI_250.2_PRS-CS)
 PGP000835 |
Chen HH et al. Nature (2025)
 Type 2 diabetes (T2D) type 2 diabetes mellitus 983,778
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018726/ScoringFiles/PGS018726.txt.gz
PGS018727
(TPMI_250.2_PRSmix+)
 PGP000835 |
Chen HH et al. Nature (2025)
 Type 2 diabetes (T2D) type 2 diabetes mellitus 1,071,475
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018727/ScoringFiles/PGS018727.txt.gz
PGS018728
(TPMI_250.2_SBayesR)
 PGP000835 |
Chen HH et al. Nature (2025)
 Type 2 diabetes (T2D) type 2 diabetes mellitus 883,373
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018728/ScoringFiles/PGS018728.txt.gz
PGS018729
(TPMI_250.4_Lassosum2)
 PGP000835 |
Chen HH et al. Nature (2025)
 Abnormal glucose Abnormal blood glucose concentration 32
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018729/ScoringFiles/PGS018729.txt.gz
PGS018730
(TPMI_250.4_LDpred2)
 PGP000835 |
Chen HH et al. Nature (2025)
 Abnormal glucose Abnormal blood glucose concentration 939,853
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018730/ScoringFiles/PGS018730.txt.gz
PGS018731
(TPMI_250.4_MegaPRS)
 PGP000835 |
Chen HH et al. Nature (2025)
 Abnormal glucose Abnormal blood glucose concentration 27,487
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018731/ScoringFiles/PGS018731.txt.gz
PGS018732
(TPMI_250.4_PRS-CS)
 PGP000835 |
Chen HH et al. Nature (2025)
 Abnormal glucose Abnormal blood glucose concentration 983,796
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018732/ScoringFiles/PGS018732.txt.gz
PGS018733
(TPMI_250.4_SBayesR)
 PGP000835 |
Chen HH et al. Nature (2025)
 Abnormal glucose Abnormal blood glucose concentration 968,581
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018733/ScoringFiles/PGS018733.txt.gz
PGS018734
(TPMI_250.6_Lassosum2)
 PGP000835 |
Chen HH et al. Nature (2025)
 Polyneuropathy in diabetes diabetic neuropathy 669
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018734/ScoringFiles/PGS018734.txt.gz
PGS018735
(TPMI_250.6_LDpred2)
 PGP000835 |
Chen HH et al. Nature (2025)
 Polyneuropathy in diabetes diabetic neuropathy 939,815
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018735/ScoringFiles/PGS018735.txt.gz
PGS018736
(TPMI_250.6_MegaPRS)
 PGP000835 |
Chen HH et al. Nature (2025)
 Polyneuropathy in diabetes diabetic neuropathy 54,980
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018736/ScoringFiles/PGS018736.txt.gz
PGS018737
(TPMI_250.6_PRS-CS)
 PGP000835 |
Chen HH et al. Nature (2025)
 Polyneuropathy in diabetes diabetic neuropathy 983,767
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018737/ScoringFiles/PGS018737.txt.gz
PGS018738
(TPMI_250.6_PRSmix+)
 PGP000835 |
Chen HH et al. Nature (2025)
 Polyneuropathy in diabetes diabetic neuropathy 1,071,477
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018738/ScoringFiles/PGS018738.txt.gz
PGS018739
(TPMI_250.6_SBayesR)
 PGP000835 |
Chen HH et al. Nature (2025)
 Polyneuropathy in diabetes diabetic neuropathy 996,392
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018739/ScoringFiles/PGS018739.txt.gz
PGS018740
(TPMI_250.7_Lassosum2)
 PGP000835 |
Chen HH et al. Nature (2025)
 Diabetic retinopathy diabetic retinopathy 96
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018740/ScoringFiles/PGS018740.txt.gz
PGS018741
(TPMI_250.7_LDpred2)
 PGP000835 |
Chen HH et al. Nature (2025)
 Diabetic retinopathy diabetic retinopathy 939,811
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018741/ScoringFiles/PGS018741.txt.gz
PGS018742
(TPMI_250.7_MegaPRS)
 PGP000835 |
Chen HH et al. Nature (2025)
 Diabetic retinopathy diabetic retinopathy 80,280
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018742/ScoringFiles/PGS018742.txt.gz
PGS018743
(TPMI_250.7_PRS-CS)
 PGP000835 |
Chen HH et al. Nature (2025)
 Diabetic retinopathy diabetic retinopathy 983,771
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018743/ScoringFiles/PGS018743.txt.gz
PGS018744
(TPMI_250.7_PRSmix+)
 PGP000835 |
Chen HH et al. Nature (2025)
 Diabetic retinopathy diabetic retinopathy 1,071,355
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018744/ScoringFiles/PGS018744.txt.gz
PGS018745
(TPMI_250.7_SBayesR)
 PGP000835 |
Chen HH et al. Nature (2025)
 Diabetic retinopathy diabetic retinopathy 1,014,773
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018745/ScoringFiles/PGS018745.txt.gz
PGS018746
(TPMI_250.21_Lassosum2)
 PGP000835 |
Chen HH et al. Nature (2025)
 Type 2 diabetes with ketoacidosis type 2 diabetes mellitus 9,978
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018746/ScoringFiles/PGS018746.txt.gz
PGS018747
(TPMI_250.21_LDpred2)
 PGP000835 |
Chen HH et al. Nature (2025)
 Type 2 diabetes with ketoacidosis type 2 diabetes mellitus 939,820
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018747/ScoringFiles/PGS018747.txt.gz
PGS018748
(TPMI_250.21_MegaPRS)
 PGP000835 |
Chen HH et al. Nature (2025)
 Type 2 diabetes with ketoacidosis type 2 diabetes mellitus 126,575
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018748/ScoringFiles/PGS018748.txt.gz
PGS018749
(TPMI_250.21_PRS-CS)
 PGP000835 |
Chen HH et al. Nature (2025)
 Type 2 diabetes with ketoacidosis type 2 diabetes mellitus 983,771
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018749/ScoringFiles/PGS018749.txt.gz
PGS018750
(TPMI_250.21_PRSmix+)
 PGP000835 |
Chen HH et al. Nature (2025)
 Type 2 diabetes with ketoacidosis type 2 diabetes mellitus 1,071,473
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018750/ScoringFiles/PGS018750.txt.gz
PGS018751
(TPMI_250.21_SBayesR)
 PGP000835 |
Chen HH et al. Nature (2025)
 Type 2 diabetes with ketoacidosis type 2 diabetes mellitus 577,953
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018751/ScoringFiles/PGS018751.txt.gz
PGS018752
(TPMI_250.22_Lassosum2)
 PGP000835 |
Chen HH et al. Nature (2025)
 Type 2 diabetes with renal manifestations type 2 diabetes mellitus 37,218
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018752/ScoringFiles/PGS018752.txt.gz
PGS018753
(TPMI_250.22_LDpred2)
 PGP000835 |
Chen HH et al. Nature (2025)
 Type 2 diabetes with renal manifestations type 2 diabetes mellitus 939,818
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018753/ScoringFiles/PGS018753.txt.gz
PGS018754
(TPMI_250.22_MegaPRS)
 PGP000835 |
Chen HH et al. Nature (2025)
 Type 2 diabetes with renal manifestations type 2 diabetes mellitus 153,238
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018754/ScoringFiles/PGS018754.txt.gz
PGS018755
(TPMI_250.22_PRS-CS)
 PGP000835 |
Chen HH et al. Nature (2025)
 Type 2 diabetes with renal manifestations type 2 diabetes mellitus 983,777
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018755/ScoringFiles/PGS018755.txt.gz
PGS018756
(TPMI_250.22_PRSmix+)
 PGP000835 |
Chen HH et al. Nature (2025)
 Type 2 diabetes with renal manifestations type 2 diabetes mellitus 1,071,472
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018756/ScoringFiles/PGS018756.txt.gz
PGS018757
(TPMI_250.22_SBayesR)
 PGP000835 |
Chen HH et al. Nature (2025)
 Type 2 diabetes with renal manifestations type 2 diabetes mellitus 979,168
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018757/ScoringFiles/PGS018757.txt.gz
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