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Polygenic Scores (PGS)
Polygenic Scores (PGS)
Filter PGS by Participant Ancestry
Individuals included in:
Any Stage [G, D, E]
All Stages combined [G + D + E]
Development [G, D]
- GWAS [G]
- Score development [D]
PGS Evaluation [E]
G
- Source of Variant Associations (
G
WAS)
D
- Score
D
evelopment/Training
E
- PGS
E
valuation
List of ancestries includes:
--
African
East Asian
South Asian
Additional Asian Ancestries
European
Greater Middle Eastern
Hispanic or Latin American
Additional Diverse Ancestries
Not Reported
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Multi-ancestry data
Ancestry legend
Multi-ancestry (including European)
Multi-ancestry (excluding European)
African
East Asian
South Asian
Additional Asian Ancestries
European
Greater Middle Eastern
Hispanic or Latin American
Additional Diverse Ancestries
Not Reported
Polygenic Score ID & Name
PGS Publication ID
(PGP)
Reported Trait
Mapped Trait(s)
(Ontology)
Number of Variants
Ancestry distribution
GWAS
Dev
Eval
Scoring File
(FTP Link)
PGS018919
(TPMI_291_PRS-CS)
PGP000835
|
Chen HH
et al.
Nature (2025)
Other specified nonpsychotic and or transient mental disorders
mental disorder
983,789
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018919/ScoringFiles/PGS018919.txt.gz
PGS018920
(TPMI_291_SBayesR)
PGP000835
|
Chen HH
et al.
Nature (2025)
Other specified nonpsychotic and or transient mental disorders
mental disorder
333,423
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018920/ScoringFiles/PGS018920.txt.gz
PGS018921
(TPMI_291.4_Lassosum2)
PGP000835
|
Chen HH
et al.
Nature (2025)
Specific nonpsychotic mental disorders due to brain damage
mental disorder
127
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018921/ScoringFiles/PGS018921.txt.gz
PGS018922
(TPMI_291.4_LDpred2)
PGP000835
|
Chen HH
et al.
Nature (2025)
Specific nonpsychotic mental disorders due to brain damage
mental disorder
939,895
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018922/ScoringFiles/PGS018922.txt.gz
PGS018923
(TPMI_291.4_MegaPRS)
PGP000835
|
Chen HH
et al.
Nature (2025)
Specific nonpsychotic mental disorders due to brain damage
mental disorder
19,578
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018923/ScoringFiles/PGS018923.txt.gz
PGS018924
(TPMI_291.4_PRS-CS)
PGP000835
|
Chen HH
et al.
Nature (2025)
Specific nonpsychotic mental disorders due to brain damage
mental disorder
983,829
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018924/ScoringFiles/PGS018924.txt.gz
PGS018925
(TPMI_291.4_SBayesR)
PGP000835
|
Chen HH
et al.
Nature (2025)
Specific nonpsychotic mental disorders due to brain damage
mental disorder
131,160
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018925/ScoringFiles/PGS018925.txt.gz
PGS018926
(TPMI_292_Lassosum2)
PGP000835
|
Chen HH
et al.
Nature (2025)
Neurological disorders
nervous system disorder
4
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018926/ScoringFiles/PGS018926.txt.gz
PGS018927
(TPMI_292_LDpred2)
PGP000835
|
Chen HH
et al.
Nature (2025)
Neurological disorders
nervous system disorder
330,541
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018927/ScoringFiles/PGS018927.txt.gz
PGS018928
(TPMI_292_MegaPRS)
PGP000835
|
Chen HH
et al.
Nature (2025)
Neurological disorders
nervous system disorder
566,907
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018928/ScoringFiles/PGS018928.txt.gz
PGS018929
(TPMI_292_PRS-CS)
PGP000835
|
Chen HH
et al.
Nature (2025)
Neurological disorders
nervous system disorder
983,821
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018929/ScoringFiles/PGS018929.txt.gz
PGS018930
(TPMI_292_SBayesR)
PGP000835
|
Chen HH
et al.
Nature (2025)
Neurological disorders
nervous system disorder
980,061
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018930/ScoringFiles/PGS018930.txt.gz
PGS018931
(TPMI_292.2_Lassosum2)
PGP000835
|
Chen HH
et al.
Nature (2025)
Mild cognitive impairment
Cognitive impairment
37,738
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018931/ScoringFiles/PGS018931.txt.gz
PGS018932
(TPMI_292.2_LDpred2)
PGP000835
|
Chen HH
et al.
Nature (2025)
Mild cognitive impairment
Cognitive impairment
271,015
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018932/ScoringFiles/PGS018932.txt.gz
PGS018933
(TPMI_292.2_MegaPRS)
PGP000835
|
Chen HH
et al.
Nature (2025)
Mild cognitive impairment
Cognitive impairment
477,076
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018933/ScoringFiles/PGS018933.txt.gz
PGS018934
(TPMI_292.2_PRS-CS)
PGP000835
|
Chen HH
et al.
Nature (2025)
Mild cognitive impairment
Cognitive impairment
983,787
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018934/ScoringFiles/PGS018934.txt.gz
PGS018935
(TPMI_292.2_SBayesR)
PGP000835
|
Chen HH
et al.
Nature (2025)
Mild cognitive impairment
Cognitive impairment
1,011,196
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018935/ScoringFiles/PGS018935.txt.gz
PGS018936
(TPMI_296.2_Lassosum2)
PGP000835
|
Chen HH
et al.
Nature (2025)
Depression
depressive disorder
230,322
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018936/ScoringFiles/PGS018936.txt.gz
PGS018937
(TPMI_296.2_LDpred2)
PGP000835
|
Chen HH
et al.
Nature (2025)
Depression
depressive disorder
939,862
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018937/ScoringFiles/PGS018937.txt.gz
PGS018938
(TPMI_296.2_MegaPRS)
PGP000835
|
Chen HH
et al.
Nature (2025)
Depression
depressive disorder
18,793
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018938/ScoringFiles/PGS018938.txt.gz
PGS018939
(TPMI_296.2_PRS-CS)
PGP000835
|
Chen HH
et al.
Nature (2025)
Depression
depressive disorder
983,806
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018939/ScoringFiles/PGS018939.txt.gz
PGS018940
(TPMI_296.2_SBayesR)
PGP000835
|
Chen HH
et al.
Nature (2025)
Depression
depressive disorder
961,120
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018940/ScoringFiles/PGS018940.txt.gz
PGS018941
(TPMI_300.11_Lassosum2)
PGP000835
|
Chen HH
et al.
Nature (2025)
Generalized anxiety disorder
generalized anxiety disorder
729,735
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018941/ScoringFiles/PGS018941.txt.gz
PGS018942
(TPMI_300.11_LDpred2)
PGP000835
|
Chen HH
et al.
Nature (2025)
Generalized anxiety disorder
generalized anxiety disorder
939,863
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018942/ScoringFiles/PGS018942.txt.gz
PGS018943
(TPMI_300.11_MegaPRS)
PGP000835
|
Chen HH
et al.
Nature (2025)
Generalized anxiety disorder
generalized anxiety disorder
21,630
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018943/ScoringFiles/PGS018943.txt.gz
PGS018944
(TPMI_300.11_PRS-CS)
PGP000835
|
Chen HH
et al.
Nature (2025)
Generalized anxiety disorder
generalized anxiety disorder
983,808
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018944/ScoringFiles/PGS018944.txt.gz
PGS018945
(TPMI_300.11_SBayesR)
PGP000835
|
Chen HH
et al.
Nature (2025)
Generalized anxiety disorder
generalized anxiety disorder
975,855
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018945/ScoringFiles/PGS018945.txt.gz
PGS018946
(TPMI_306_Lassosum2)
PGP000835
|
Chen HH
et al.
Nature (2025)
Other mental disorder
mental disorder
393,402
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018946/ScoringFiles/PGS018946.txt.gz
PGS018947
(TPMI_306_LDpred2)
PGP000835
|
Chen HH
et al.
Nature (2025)
Other mental disorder
mental disorder
402,973
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018947/ScoringFiles/PGS018947.txt.gz
PGS018948
(TPMI_306_MegaPRS)
PGP000835
|
Chen HH
et al.
Nature (2025)
Other mental disorder
mental disorder
22,265
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018948/ScoringFiles/PGS018948.txt.gz
PGS018949
(TPMI_306_PRS-CS)
PGP000835
|
Chen HH
et al.
Nature (2025)
Other mental disorder
mental disorder
983,807
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018949/ScoringFiles/PGS018949.txt.gz
PGS018950
(TPMI_306_SBayesR)
PGP000835
|
Chen HH
et al.
Nature (2025)
Other mental disorder
mental disorder
922,093
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018950/ScoringFiles/PGS018950.txt.gz
PGS018951
(TPMI_315_Lassosum2)
PGP000835
|
Chen HH
et al.
Nature (2025)
Develomental delays and disorders
specific developmental disorder
21
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018951/ScoringFiles/PGS018951.txt.gz
PGS018952
(TPMI_315_LDpred2)
PGP000835
|
Chen HH
et al.
Nature (2025)
Develomental delays and disorders
specific developmental disorder
178,694
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018952/ScoringFiles/PGS018952.txt.gz
PGS018953
(TPMI_315_MegaPRS)
PGP000835
|
Chen HH
et al.
Nature (2025)
Develomental delays and disorders
specific developmental disorder
28,656
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018953/ScoringFiles/PGS018953.txt.gz
PGS018954
(TPMI_315_PRS-CS)
PGP000835
|
Chen HH
et al.
Nature (2025)
Develomental delays and disorders
specific developmental disorder
983,831
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018954/ScoringFiles/PGS018954.txt.gz
PGS018955
(TPMI_315_SBayesR)
PGP000835
|
Chen HH
et al.
Nature (2025)
Develomental delays and disorders
specific developmental disorder
1,013,967
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018955/ScoringFiles/PGS018955.txt.gz
PGS018956
(TPMI_317_Lassosum2)
PGP000835
|
Chen HH
et al.
Nature (2025)
Alcohol related disorders
alcohol-related disorders
30
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018956/ScoringFiles/PGS018956.txt.gz
PGS018957
(TPMI_317_LDpred2)
PGP000835
|
Chen HH
et al.
Nature (2025)
Alcohol related disorders
alcohol-related disorders
939,840
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018957/ScoringFiles/PGS018957.txt.gz
PGS018958
(TPMI_317_MegaPRS)
PGP000835
|
Chen HH
et al.
Nature (2025)
Alcohol related disorders
alcohol-related disorders
22,608
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018958/ScoringFiles/PGS018958.txt.gz
PGS018959
(TPMI_317_PRS-CS)
PGP000835
|
Chen HH
et al.
Nature (2025)
Alcohol related disorders
alcohol-related disorders
983,786
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018959/ScoringFiles/PGS018959.txt.gz
PGS018960
(TPMI_317_SBayesR)
PGP000835
|
Chen HH
et al.
Nature (2025)
Alcohol related disorders
alcohol-related disorders
913,261
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018960/ScoringFiles/PGS018960.txt.gz
PGS018961
(TPMI_317.1_Lassosum2)
PGP000835
|
Chen HH
et al.
Nature (2025)
Alcoholism
alcohol dependence
15
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018961/ScoringFiles/PGS018961.txt.gz
PGS018962
(TPMI_317.1_LDpred2)
PGP000835
|
Chen HH
et al.
Nature (2025)
Alcoholism
alcohol dependence
939,838
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018962/ScoringFiles/PGS018962.txt.gz
PGS018963
(TPMI_317.1_MegaPRS)
PGP000835
|
Chen HH
et al.
Nature (2025)
Alcoholism
alcohol dependence
25,361
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018963/ScoringFiles/PGS018963.txt.gz
PGS018964
(TPMI_317.1_PRS-CS)
PGP000835
|
Chen HH
et al.
Nature (2025)
Alcoholism
alcohol dependence
983,785
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018964/ScoringFiles/PGS018964.txt.gz
PGS018965
(TPMI_317.1_SBayesR)
PGP000835
|
Chen HH
et al.
Nature (2025)
Alcoholism
alcohol dependence
1,013,582
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018965/ScoringFiles/PGS018965.txt.gz
PGS018966
(TPMI_327.5_Lassosum2)
PGP000835
|
Chen HH
et al.
Nature (2025)
Parasomnia
Parasomnia
5
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018966/ScoringFiles/PGS018966.txt.gz
PGS018967
(TPMI_327.5_LDpred2)
PGP000835
|
Chen HH
et al.
Nature (2025)
Parasomnia
Parasomnia
939,819
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018967/ScoringFiles/PGS018967.txt.gz
PGS018968
(TPMI_327.5_MegaPRS)
PGP000835
|
Chen HH
et al.
Nature (2025)
Parasomnia
Parasomnia
516,575
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018968/ScoringFiles/PGS018968.txt.gz
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