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Polygenic Scores (PGS)
Polygenic Scores (PGS)
Filter PGS by Participant Ancestry
Individuals included in:
Any Stage [G, D, E]
All Stages combined [G + D + E]
Development [G, D]
- GWAS [G]
- Score development [D]
PGS Evaluation [E]
G
- Source of Variant Associations (
G
WAS)
D
- Score
D
evelopment/Training
E
- PGS
E
valuation
List of ancestries includes:
--
African
East Asian
South Asian
Additional Asian Ancestries
European
Greater Middle Eastern
Hispanic or Latin American
Additional Diverse Ancestries
Not Reported
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Multi-ancestry data
Ancestry legend
Multi-ancestry (including European)
Multi-ancestry (excluding European)
African
East Asian
South Asian
Additional Asian Ancestries
European
Greater Middle Eastern
Hispanic or Latin American
Additional Diverse Ancestries
Not Reported
Polygenic Score ID & Name
PGS Publication ID
(PGP)
Reported Trait
Mapped Trait(s)
(Ontology)
Number of Variants
Ancestry distribution
GWAS
Dev
Eval
Scoring File
(FTP Link)
PGS019719
(TPMI_729.1_MegaPRS)
PGP000835
|
Chen HH
et al.
Nature (2025)
Rheumatism unspecified and fibrositis
rheumatic disorder
14,417
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019719/ScoringFiles/PGS019719.txt.gz
PGS019720
(TPMI_729.1_PRS-CS)
PGP000835
|
Chen HH
et al.
Nature (2025)
Rheumatism unspecified and fibrositis
rheumatic disorder
983,795
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019720/ScoringFiles/PGS019720.txt.gz
PGS019721
(TPMI_729.1_SBayesR)
PGP000835
|
Chen HH
et al.
Nature (2025)
Rheumatism unspecified and fibrositis
rheumatic disorder
992,683
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019721/ScoringFiles/PGS019721.txt.gz
PGS019722
(TPMI_743_Lassosum2)
PGP000835
|
Chen HH
et al.
Nature (2025)
Osteoporosis osteopenia and pathological fracture
osteoporosis
,
bone fracture
69,652
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019722/ScoringFiles/PGS019722.txt.gz
PGS019723
(TPMI_743_LDpred2)
PGP000835
|
Chen HH
et al.
Nature (2025)
Osteoporosis osteopenia and pathological fracture
osteoporosis
,
bone fracture
365,313
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019723/ScoringFiles/PGS019723.txt.gz
PGS019724
(TPMI_743_MegaPRS)
PGP000835
|
Chen HH
et al.
Nature (2025)
Osteoporosis osteopenia and pathological fracture
osteoporosis
,
bone fracture
16,942
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019724/ScoringFiles/PGS019724.txt.gz
PGS019725
(TPMI_743_PRS-CS)
PGP000835
|
Chen HH
et al.
Nature (2025)
Osteoporosis osteopenia and pathological fracture
osteoporosis
,
bone fracture
983,829
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019725/ScoringFiles/PGS019725.txt.gz
PGS019726
(TPMI_743_SBayesR)
PGP000835
|
Chen HH
et al.
Nature (2025)
Osteoporosis osteopenia and pathological fracture
osteoporosis
,
bone fracture
957,929
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019726/ScoringFiles/PGS019726.txt.gz
PGS019727
(TPMI_743.11_Lassosum2)
PGP000835
|
Chen HH
et al.
Nature (2025)
Osteoporosis NOS
osteoporosis
419
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019727/ScoringFiles/PGS019727.txt.gz
PGS019728
(TPMI_743.11_LDpred2)
PGP000835
|
Chen HH
et al.
Nature (2025)
Osteoporosis NOS
osteoporosis
317,022
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019728/ScoringFiles/PGS019728.txt.gz
PGS019729
(TPMI_743.11_MegaPRS)
PGP000835
|
Chen HH
et al.
Nature (2025)
Osteoporosis NOS
osteoporosis
27,110
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019729/ScoringFiles/PGS019729.txt.gz
PGS019730
(TPMI_743.11_PRS-CS)
PGP000835
|
Chen HH
et al.
Nature (2025)
Osteoporosis NOS
osteoporosis
983,826
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019730/ScoringFiles/PGS019730.txt.gz
PGS019731
(TPMI_743.11_SBayesR)
PGP000835
|
Chen HH
et al.
Nature (2025)
Osteoporosis NOS
osteoporosis
989,191
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019731/ScoringFiles/PGS019731.txt.gz
PGS019732
(TPMI_764_Lassosum2)
PGP000835
|
Chen HH
et al.
Nature (2025)
Sciatica
Sciatica
1,817
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019732/ScoringFiles/PGS019732.txt.gz
PGS019733
(TPMI_764_LDpred2)
PGP000835
|
Chen HH
et al.
Nature (2025)
Sciatica
Sciatica
939,890
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019733/ScoringFiles/PGS019733.txt.gz
PGS019734
(TPMI_764_MegaPRS)
PGP000835
|
Chen HH
et al.
Nature (2025)
Sciatica
Sciatica
541,283
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019734/ScoringFiles/PGS019734.txt.gz
PGS019735
(TPMI_764_PRS-CS)
PGP000835
|
Chen HH
et al.
Nature (2025)
Sciatica
Sciatica
983,826
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019735/ScoringFiles/PGS019735.txt.gz
PGS019736
(TPMI_764_SBayesR)
PGP000835
|
Chen HH
et al.
Nature (2025)
Sciatica
Sciatica
982,896
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019736/ScoringFiles/PGS019736.txt.gz
PGS019737
(TPMI_772_Lassosum2)
PGP000835
|
Chen HH
et al.
Nature (2025)
Symptoms of the muscles
muscular disease
56,926
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019737/ScoringFiles/PGS019737.txt.gz
PGS019738
(TPMI_772_LDpred2)
PGP000835
|
Chen HH
et al.
Nature (2025)
Symptoms of the muscles
muscular disease
939,897
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019738/ScoringFiles/PGS019738.txt.gz
PGS019739
(TPMI_772_MegaPRS)
PGP000835
|
Chen HH
et al.
Nature (2025)
Symptoms of the muscles
muscular disease
22,400
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019739/ScoringFiles/PGS019739.txt.gz
PGS019740
(TPMI_772_PRS-CS)
PGP000835
|
Chen HH
et al.
Nature (2025)
Symptoms of the muscles
muscular disease
983,830
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019740/ScoringFiles/PGS019740.txt.gz
PGS019741
(TPMI_772_SBayesR)
PGP000835
|
Chen HH
et al.
Nature (2025)
Symptoms of the muscles
muscular disease
981,590
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019741/ScoringFiles/PGS019741.txt.gz
PGS019742
(TPMI_773_Lassosum2)
PGP000835
|
Chen HH
et al.
Nature (2025)
Pain in limb
Limb pain
10,074
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019742/ScoringFiles/PGS019742.txt.gz
PGS019743
(TPMI_773_LDpred2)
PGP000835
|
Chen HH
et al.
Nature (2025)
Pain in limb
Limb pain
939,894
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019743/ScoringFiles/PGS019743.txt.gz
PGS019744
(TPMI_773_MegaPRS)
PGP000835
|
Chen HH
et al.
Nature (2025)
Pain in limb
Limb pain
492,963
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019744/ScoringFiles/PGS019744.txt.gz
PGS019745
(TPMI_773_PRS-CS)
PGP000835
|
Chen HH
et al.
Nature (2025)
Pain in limb
Limb pain
983,825
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019745/ScoringFiles/PGS019745.txt.gz
PGS019746
(TPMI_773_SBayesR)
PGP000835
|
Chen HH
et al.
Nature (2025)
Pain in limb
Limb pain
1,002,185
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019746/ScoringFiles/PGS019746.txt.gz
PGS019747
(TPMI_783_Lassosum2)
PGP000835
|
Chen HH
et al.
Nature (2025)
Fever of unknown origin
fever of unknown origin
44
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019747/ScoringFiles/PGS019747.txt.gz
PGS019748
(TPMI_783_LDpred2)
PGP000835
|
Chen HH
et al.
Nature (2025)
Fever of unknown origin
fever of unknown origin
151,556
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019748/ScoringFiles/PGS019748.txt.gz
PGS019749
(TPMI_783_MegaPRS)
PGP000835
|
Chen HH
et al.
Nature (2025)
Fever of unknown origin
fever of unknown origin
556,003
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019749/ScoringFiles/PGS019749.txt.gz
PGS019750
(TPMI_783_PRS-CS)
PGP000835
|
Chen HH
et al.
Nature (2025)
Fever of unknown origin
fever of unknown origin
983,825
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019750/ScoringFiles/PGS019750.txt.gz
PGS019751
(TPMI_783_SBayesR)
PGP000835
|
Chen HH
et al.
Nature (2025)
Fever of unknown origin
fever of unknown origin
986,365
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019751/ScoringFiles/PGS019751.txt.gz
PGS019752
(TPMI_790_Lassosum2)
PGP000835
|
Chen HH
et al.
Nature (2025)
Nonspecific findings on examination of blood
abnormal result of function studies
223,270
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019752/ScoringFiles/PGS019752.txt.gz
PGS019753
(TPMI_790_LDpred2)
PGP000835
|
Chen HH
et al.
Nature (2025)
Nonspecific findings on examination of blood
abnormal result of function studies
939,891
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019753/ScoringFiles/PGS019753.txt.gz
PGS019754
(TPMI_790_MegaPRS)
PGP000835
|
Chen HH
et al.
Nature (2025)
Nonspecific findings on examination of blood
abnormal result of function studies
18,474
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019754/ScoringFiles/PGS019754.txt.gz
PGS019755
(TPMI_790_PRS-CS)
PGP000835
|
Chen HH
et al.
Nature (2025)
Nonspecific findings on examination of blood
abnormal result of function studies
983,826
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019755/ScoringFiles/PGS019755.txt.gz
PGS019756
(TPMI_790_SBayesR)
PGP000835
|
Chen HH
et al.
Nature (2025)
Nonspecific findings on examination of blood
abnormal result of function studies
959,344
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019756/ScoringFiles/PGS019756.txt.gz
PGS019757
(TPMI_790.6_Lassosum2)
PGP000835
|
Chen HH
et al.
Nature (2025)
Other abnormal blood chemistry
Abnormal circulating sodium concentration
4
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019757/ScoringFiles/PGS019757.txt.gz
PGS019758
(TPMI_790.6_LDpred2)
PGP000835
|
Chen HH
et al.
Nature (2025)
Other abnormal blood chemistry
Abnormal circulating sodium concentration
292,919
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019758/ScoringFiles/PGS019758.txt.gz
PGS019759
(TPMI_790.6_MegaPRS)
PGP000835
|
Chen HH
et al.
Nature (2025)
Other abnormal blood chemistry
Abnormal circulating sodium concentration
18,692
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019759/ScoringFiles/PGS019759.txt.gz
PGS019760
(TPMI_790.6_PRS-CS)
PGP000835
|
Chen HH
et al.
Nature (2025)
Other abnormal blood chemistry
Abnormal circulating sodium concentration
983,825
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019760/ScoringFiles/PGS019760.txt.gz
PGS019761
(TPMI_790.6_PRSmix+)
PGP000835
|
Chen HH
et al.
Nature (2025)
Other abnormal blood chemistry
Abnormal circulating sodium concentration
1,071,461
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019761/ScoringFiles/PGS019761.txt.gz
PGS019762
(TPMI_790.6_SBayesR)
PGP000835
|
Chen HH
et al.
Nature (2025)
Other abnormal blood chemistry
Abnormal circulating sodium concentration
903,627
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019762/ScoringFiles/PGS019762.txt.gz
PGS019763
(TPMI_795_Lassosum2)
PGP000835
|
Chen HH
et al.
Nature (2025)
Other and nonspecific abnormal cytological histological and immunological findings
cytological, histological or immunological finding
78
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019763/ScoringFiles/PGS019763.txt.gz
PGS019764
(TPMI_795_LDpred2)
PGP000835
|
Chen HH
et al.
Nature (2025)
Other and nonspecific abnormal cytological histological and immunological findings
cytological, histological or immunological finding
176,416
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019764/ScoringFiles/PGS019764.txt.gz
PGS019765
(TPMI_795_MegaPRS)
PGP000835
|
Chen HH
et al.
Nature (2025)
Other and nonspecific abnormal cytological histological and immunological findings
cytological, histological or immunological finding
22,807
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019765/ScoringFiles/PGS019765.txt.gz
PGS019766
(TPMI_795_PRS-CS)
PGP000835
|
Chen HH
et al.
Nature (2025)
Other and nonspecific abnormal cytological histological and immunological findings
cytological, histological or immunological finding
983,791
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019766/ScoringFiles/PGS019766.txt.gz
PGS019767
(TPMI_795_SBayesR)
PGP000835
|
Chen HH
et al.
Nature (2025)
Other and nonspecific abnormal cytological histological and immunological findings
cytological, histological or immunological finding
972,527
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019767/ScoringFiles/PGS019767.txt.gz
PGS019768
(TPMI_795.8_Lassosum2)
PGP000835
|
Chen HH
et al.
Nature (2025)
Abnormal tumor markers
cancer biomarker measurement
141
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019768/ScoringFiles/PGS019768.txt.gz
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