Polygenic Scores (PGS)

Filter PGS by Participant Ancestry
Individuals included in:
G - Source of Variant Associations (GWAS)
D - Score Development/Training
E - PGS Evaluation
List of ancestries includes:
Display options:
Ancestry legend
Multi-ancestry (including European)
Multi-ancestry (excluding European)
African
East Asian
South Asian
Additional Asian Ancestries
European
Greater Middle Eastern
Hispanic or Latin American
Additional Diverse Ancestries
Not Reported
Polygenic Score ID & Name PGS Publication ID (PGP) Reported Trait Mapped Trait(s) (Ontology) Number of Variants Ancestry distribution
GWAS
Dev
Eval
Scoring File (FTP Link)
PGS019658
(TPMI_714_MegaPRS)
PGP000835 |
Chen HH et al. Nature (2025)
Rheumatoid arthritis and other inflammatory polyarthropathies rheumatoid arthritis 28,836
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019658/ScoringFiles/PGS019658.txt.gz
PGS019659
(TPMI_714_PRS-CS)
PGP000835 |
Chen HH et al. Nature (2025)
Rheumatoid arthritis and other inflammatory polyarthropathies rheumatoid arthritis 983,784
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019659/ScoringFiles/PGS019659.txt.gz
PGS019660
(TPMI_714_SBayesR)
PGP000835 |
Chen HH et al. Nature (2025)
Rheumatoid arthritis and other inflammatory polyarthropathies rheumatoid arthritis 554,495
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019660/ScoringFiles/PGS019660.txt.gz
PGS019661
(TPMI_714.1_Lassosum2)
PGP000835 |
Chen HH et al. Nature (2025)
Rheumatoid arthritis rheumatoid arthritis 2,493
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019661/ScoringFiles/PGS019661.txt.gz
PGS019662
(TPMI_714.1_LDpred2)
PGP000835 |
Chen HH et al. Nature (2025)
Rheumatoid arthritis rheumatoid arthritis 939,827
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019662/ScoringFiles/PGS019662.txt.gz
PGS019663
(TPMI_714.1_MegaPRS)
PGP000835 |
Chen HH et al. Nature (2025)
Rheumatoid arthritis rheumatoid arthritis 33,790
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019663/ScoringFiles/PGS019663.txt.gz
PGS019664
(TPMI_714.1_PRS-CS)
PGP000835 |
Chen HH et al. Nature (2025)
Rheumatoid arthritis rheumatoid arthritis 983,784
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019664/ScoringFiles/PGS019664.txt.gz
PGS019665
(TPMI_714.1_SBayesR)
PGP000835 |
Chen HH et al. Nature (2025)
Rheumatoid arthritis rheumatoid arthritis 913,921
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019665/ScoringFiles/PGS019665.txt.gz
PGS019666
(TPMI_715_Lassosum2)
PGP000835 |
Chen HH et al. Nature (2025)
Other inflammatory spondylopathies inflammatory spondylopathy 27
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019666/ScoringFiles/PGS019666.txt.gz
PGS019667
(TPMI_715_LDpred2)
PGP000835 |
Chen HH et al. Nature (2025)
Other inflammatory spondylopathies inflammatory spondylopathy 939,889
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019667/ScoringFiles/PGS019667.txt.gz
PGS019668
(TPMI_715_MegaPRS)
PGP000835 |
Chen HH et al. Nature (2025)
Other inflammatory spondylopathies inflammatory spondylopathy 294,406
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019668/ScoringFiles/PGS019668.txt.gz
PGS019669
(TPMI_715_PRS-CS)
PGP000835 |
Chen HH et al. Nature (2025)
Other inflammatory spondylopathies inflammatory spondylopathy 983,832
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019669/ScoringFiles/PGS019669.txt.gz
PGS019670
(TPMI_715_SBayesR)
PGP000835 |
Chen HH et al. Nature (2025)
Other inflammatory spondylopathies inflammatory spondylopathy 791,011
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019670/ScoringFiles/PGS019670.txt.gz
PGS019671
(TPMI_715.2_Lassosum2)
PGP000835 |
Chen HH et al. Nature (2025)
Ankylosing spondylitis ankylosing spondylitis 20
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019671/ScoringFiles/PGS019671.txt.gz
PGS019672
(TPMI_715.2_LDpred2)
PGP000835 |
Chen HH et al. Nature (2025)
Ankylosing spondylitis ankylosing spondylitis 939,888
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019672/ScoringFiles/PGS019672.txt.gz
PGS019673
(TPMI_715.2_MegaPRS)
PGP000835 |
Chen HH et al. Nature (2025)
Ankylosing spondylitis ankylosing spondylitis 292,554
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019673/ScoringFiles/PGS019673.txt.gz
PGS019674
(TPMI_715.2_PRS-CS)
PGP000835 |
Chen HH et al. Nature (2025)
Ankylosing spondylitis ankylosing spondylitis 983,830
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019674/ScoringFiles/PGS019674.txt.gz
PGS019675
(TPMI_715.2_PRSmix+)
PGP000835 |
Chen HH et al. Nature (2025)
Ankylosing spondylitis ankylosing spondylitis 1,071,343
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019675/ScoringFiles/PGS019675.txt.gz
PGS019676
(TPMI_715.2_SBayesR)
PGP000835 |
Chen HH et al. Nature (2025)
Ankylosing spondylitis ankylosing spondylitis 940,059
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019676/ScoringFiles/PGS019676.txt.gz
PGS019677
(TPMI_716_Lassosum2)
PGP000835 |
Chen HH et al. Nature (2025)
Other arthropathies arthropathy 22
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019677/ScoringFiles/PGS019677.txt.gz
PGS019678
(TPMI_716_LDpred2)
PGP000835 |
Chen HH et al. Nature (2025)
Other arthropathies arthropathy 939,889
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019678/ScoringFiles/PGS019678.txt.gz
PGS019679
(TPMI_716_MegaPRS)
PGP000835 |
Chen HH et al. Nature (2025)
Other arthropathies arthropathy 11,934
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019679/ScoringFiles/PGS019679.txt.gz
PGS019680
(TPMI_716_PRS-CS)
PGP000835 |
Chen HH et al. Nature (2025)
Other arthropathies arthropathy 983,822
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019680/ScoringFiles/PGS019680.txt.gz
PGS019681
(TPMI_716_SBayesR)
PGP000835 |
Chen HH et al. Nature (2025)
Other arthropathies arthropathy 953,818
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019681/ScoringFiles/PGS019681.txt.gz
PGS019682
(TPMI_716.1_Lassosum2)
PGP000835 |
Chen HH et al. Nature (2025)
Unspecified polyarthropathy or polyarthritis arthropathy 5
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019682/ScoringFiles/PGS019682.txt.gz
PGS019683
(TPMI_716.1_LDpred2)
PGP000835 |
Chen HH et al. Nature (2025)
Unspecified polyarthropathy or polyarthritis arthropathy 939,829
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019683/ScoringFiles/PGS019683.txt.gz
PGS019684
(TPMI_716.1_MegaPRS)
PGP000835 |
Chen HH et al. Nature (2025)
Unspecified polyarthropathy or polyarthritis arthropathy 483,730
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019684/ScoringFiles/PGS019684.txt.gz
PGS019685
(TPMI_716.1_PRS-CS)
PGP000835 |
Chen HH et al. Nature (2025)
Unspecified polyarthropathy or polyarthritis arthropathy 983,781
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019685/ScoringFiles/PGS019685.txt.gz
PGS019686
(TPMI_716.1_SBayesR)
PGP000835 |
Chen HH et al. Nature (2025)
Unspecified polyarthropathy or polyarthritis arthropathy 981,996
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019686/ScoringFiles/PGS019686.txt.gz
PGS019687
(TPMI_716.8_Lassosum2)
PGP000835 |
Chen HH et al. Nature (2025)
Palindromic rheumatism palindromic rheumatism 40
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019687/ScoringFiles/PGS019687.txt.gz
PGS019688
(TPMI_716.8_LDpred2)
PGP000835 |
Chen HH et al. Nature (2025)
Palindromic rheumatism palindromic rheumatism 939,830
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019688/ScoringFiles/PGS019688.txt.gz
PGS019689
(TPMI_716.8_MegaPRS)
PGP000835 |
Chen HH et al. Nature (2025)
Palindromic rheumatism palindromic rheumatism 402,924
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019689/ScoringFiles/PGS019689.txt.gz
PGS019690
(TPMI_716.8_PRS-CS)
PGP000835 |
Chen HH et al. Nature (2025)
Palindromic rheumatism palindromic rheumatism 983,781
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019690/ScoringFiles/PGS019690.txt.gz
PGS019691
(TPMI_716.8_SBayesR)
PGP000835 |
Chen HH et al. Nature (2025)
Palindromic rheumatism palindromic rheumatism 1,000,628
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019691/ScoringFiles/PGS019691.txt.gz
PGS019692
(TPMI_716.9_Lassosum2)
PGP000835 |
Chen HH et al. Nature (2025)
Arthropathy NOS arthropathy 19
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019692/ScoringFiles/PGS019692.txt.gz
PGS019693
(TPMI_716.9_LDpred2)
PGP000835 |
Chen HH et al. Nature (2025)
Arthropathy NOS arthropathy 939,890
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019693/ScoringFiles/PGS019693.txt.gz
PGS019694
(TPMI_716.9_MegaPRS)
PGP000835 |
Chen HH et al. Nature (2025)
Arthropathy NOS arthropathy 485,041
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019694/ScoringFiles/PGS019694.txt.gz
PGS019695
(TPMI_716.9_PRS-CS)
PGP000835 |
Chen HH et al. Nature (2025)
Arthropathy NOS arthropathy 983,823
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019695/ScoringFiles/PGS019695.txt.gz
PGS019696
(TPMI_716.9_SBayesR)
PGP000835 |
Chen HH et al. Nature (2025)
Arthropathy NOS arthropathy 928,818
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019696/ScoringFiles/PGS019696.txt.gz
PGS019697
(TPMI_723_Lassosum2)
PGP000835 |
Chen HH et al. Nature (2025)
Other disorders of cervical region cervical neck region 148,767
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019697/ScoringFiles/PGS019697.txt.gz
PGS019698
(TPMI_723_LDpred2)
PGP000835 |
Chen HH et al. Nature (2025)
Other disorders of cervical region cervical neck region 939,845
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019698/ScoringFiles/PGS019698.txt.gz
PGS019699
(TPMI_723_MegaPRS)
PGP000835 |
Chen HH et al. Nature (2025)
Other disorders of cervical region cervical neck region 523,485
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019699/ScoringFiles/PGS019699.txt.gz
PGS019700
(TPMI_723_PRS-CS)
PGP000835 |
Chen HH et al. Nature (2025)
Other disorders of cervical region cervical neck region 983,788
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019700/ScoringFiles/PGS019700.txt.gz
PGS019701
(TPMI_723_SBayesR)
PGP000835 |
Chen HH et al. Nature (2025)
Other disorders of cervical region cervical neck region 998,101
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019701/ScoringFiles/PGS019701.txt.gz
PGS019702
(TPMI_724_Lassosum2)
PGP000835 |
Chen HH et al. Nature (2025)
Other and unspecified disorders of back Abnormality of the vertebral column 113,785
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019702/ScoringFiles/PGS019702.txt.gz
PGS019703
(TPMI_724_LDpred2)
PGP000835 |
Chen HH et al. Nature (2025)
Other and unspecified disorders of back Abnormality of the vertebral column 939,846
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019703/ScoringFiles/PGS019703.txt.gz
PGS019704
(TPMI_724_MegaPRS)
PGP000835 |
Chen HH et al. Nature (2025)
Other and unspecified disorders of back Abnormality of the vertebral column 22,219
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019704/ScoringFiles/PGS019704.txt.gz
PGS019705
(TPMI_724_PRS-CS)
PGP000835 |
Chen HH et al. Nature (2025)
Other and unspecified disorders of back Abnormality of the vertebral column 983,790
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019705/ScoringFiles/PGS019705.txt.gz
PGS019706
(TPMI_724_SBayesR)
PGP000835 |
Chen HH et al. Nature (2025)
Other and unspecified disorders of back Abnormality of the vertebral column 939,653
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019706/ScoringFiles/PGS019706.txt.gz
PGS019707
(TPMI_728_Lassosum2)
PGP000835 |
Chen HH et al. Nature (2025)
Disorders of muscle ligament and fascia soft tissue disease 461,473
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019707/ScoringFiles/PGS019707.txt.gz