Polygenic Scores (PGS)

Filter PGS by Participant Ancestry
Individuals included in:
G - Source of Variant Associations (GWAS)
D - Score Development/Training
E - PGS Evaluation
List of ancestries includes:
Display options:
Ancestry legend
Multi-ancestry (including European)
Multi-ancestry (excluding European)
African
East Asian
South Asian
Additional Asian Ancestries
European
Greater Middle Eastern
Hispanic or Latin American
Additional Diverse Ancestries
Not Reported
Polygenic Score ID & Name PGS Publication ID (PGP) Reported Trait Mapped Trait(s) (Ontology) Number of Variants Ancestry distribution
GWAS
Dev
Eval
Scoring File (FTP Link)
PGS019619
(TPMI_696.41_MegaPRS)
PGP000835 |
Chen HH et al. Nature (2025)
Psoriasis vulgaris psoriasis vulgaris 49,531
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019619/ScoringFiles/PGS019619.txt.gz
PGS019620
(TPMI_696.41_PRS-CS)
PGP000835 |
Chen HH et al. Nature (2025)
Psoriasis vulgaris psoriasis vulgaris 983,756
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019620/ScoringFiles/PGS019620.txt.gz
PGS019621
(TPMI_696.41_PRSmix+)
PGP000835 |
Chen HH et al. Nature (2025)
Psoriasis vulgaris psoriasis vulgaris 1,071,390
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019621/ScoringFiles/PGS019621.txt.gz
PGS019622
(TPMI_696.41_SBayesR)
PGP000835 |
Chen HH et al. Nature (2025)
Psoriasis vulgaris psoriasis vulgaris 59,819
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019622/ScoringFiles/PGS019622.txt.gz
PGS019623
(TPMI_696.42_Lassosum2)
PGP000835 |
Chen HH et al. Nature (2025)
Psoriatic arthropathy psoriatic arthritis 1,224
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019623/ScoringFiles/PGS019623.txt.gz
PGS019624
(TPMI_696.42_LDpred2)
PGP000835 |
Chen HH et al. Nature (2025)
Psoriatic arthropathy psoriatic arthritis 939,799
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019624/ScoringFiles/PGS019624.txt.gz
PGS019625
(TPMI_696.42_MegaPRS)
PGP000835 |
Chen HH et al. Nature (2025)
Psoriatic arthropathy psoriatic arthritis 37,037
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019625/ScoringFiles/PGS019625.txt.gz
PGS019626
(TPMI_696.42_PRS-CS)
PGP000835 |
Chen HH et al. Nature (2025)
Psoriatic arthropathy psoriatic arthritis 983,751
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019626/ScoringFiles/PGS019626.txt.gz
PGS019627
(TPMI_696.42_PRSmix+)
PGP000835 |
Chen HH et al. Nature (2025)
Psoriatic arthropathy psoriatic arthritis 1,071,405
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019627/ScoringFiles/PGS019627.txt.gz
PGS019628
(TPMI_696.42_SBayesR)
PGP000835 |
Chen HH et al. Nature (2025)
Psoriatic arthropathy psoriatic arthritis 996,498
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019628/ScoringFiles/PGS019628.txt.gz
PGS019629
(TPMI_706_Lassosum2)
PGP000835 |
Chen HH et al. Nature (2025)
Diseases of sebaceous glands sebaceous gland disorder 732,290
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019629/ScoringFiles/PGS019629.txt.gz
PGS019630
(TPMI_706_LDpred2)
PGP000835 |
Chen HH et al. Nature (2025)
Diseases of sebaceous glands sebaceous gland disorder 338,113
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019630/ScoringFiles/PGS019630.txt.gz
PGS019631
(TPMI_706_MegaPRS)
PGP000835 |
Chen HH et al. Nature (2025)
Diseases of sebaceous glands sebaceous gland disorder 464,295
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019631/ScoringFiles/PGS019631.txt.gz
PGS019632
(TPMI_706_PRS-CS)
PGP000835 |
Chen HH et al. Nature (2025)
Diseases of sebaceous glands sebaceous gland disorder 983,780
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019632/ScoringFiles/PGS019632.txt.gz
PGS019633
(TPMI_706_SBayesR)
PGP000835 |
Chen HH et al. Nature (2025)
Diseases of sebaceous glands sebaceous gland disorder 959,673
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019633/ScoringFiles/PGS019633.txt.gz
PGS019634
(TPMI_706.1_Lassosum2)
PGP000835 |
Chen HH et al. Nature (2025)
Acne acne 565,294
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019634/ScoringFiles/PGS019634.txt.gz
PGS019635
(TPMI_706.1_LDpred2)
PGP000835 |
Chen HH et al. Nature (2025)
Acne acne 273,955
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019635/ScoringFiles/PGS019635.txt.gz
PGS019636
(TPMI_706.1_MegaPRS)
PGP000835 |
Chen HH et al. Nature (2025)
Acne acne 17,458
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019636/ScoringFiles/PGS019636.txt.gz
PGS019637
(TPMI_706.1_PRS-CS)
PGP000835 |
Chen HH et al. Nature (2025)
Acne acne 983,822
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019637/ScoringFiles/PGS019637.txt.gz
PGS019638
(TPMI_706.1_SBayesR)
PGP000835 |
Chen HH et al. Nature (2025)
Acne acne 961,798
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019638/ScoringFiles/PGS019638.txt.gz
PGS019639
(TPMI_709_Lassosum2)
PGP000835 |
Chen HH et al. Nature (2025)
Diffuse diseases of connective tissue connective tissue disorder 2,287
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019639/ScoringFiles/PGS019639.txt.gz
PGS019640
(TPMI_709_LDpred2)
PGP000835 |
Chen HH et al. Nature (2025)
Diffuse diseases of connective tissue connective tissue disorder 939,811
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019640/ScoringFiles/PGS019640.txt.gz
PGS019641
(TPMI_709_MegaPRS)
PGP000835 |
Chen HH et al. Nature (2025)
Diffuse diseases of connective tissue connective tissue disorder 54,458
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019641/ScoringFiles/PGS019641.txt.gz
PGS019642
(TPMI_709_PRS-CS)
PGP000835 |
Chen HH et al. Nature (2025)
Diffuse diseases of connective tissue connective tissue disorder 983,767
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019642/ScoringFiles/PGS019642.txt.gz
PGS019643
(TPMI_709_PRSmix+)
PGP000835 |
Chen HH et al. Nature (2025)
Diffuse diseases of connective tissue connective tissue disorder 1,071,399
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019643/ScoringFiles/PGS019643.txt.gz
PGS019644
(TPMI_709_SBayesR)
PGP000835 |
Chen HH et al. Nature (2025)
Diffuse diseases of connective tissue connective tissue disorder 127,143
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019644/ScoringFiles/PGS019644.txt.gz
PGS019645
(TPMI_709.2_Lassosum2)
PGP000835 |
Chen HH et al. Nature (2025)
Sicca syndrome Sjogren syndrome 1,224
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019645/ScoringFiles/PGS019645.txt.gz
PGS019646
(TPMI_709.2_LDpred2)
PGP000835 |
Chen HH et al. Nature (2025)
Sicca syndrome Sjogren syndrome 939,810
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019646/ScoringFiles/PGS019646.txt.gz
PGS019647
(TPMI_709.2_MegaPRS)
PGP000835 |
Chen HH et al. Nature (2025)
Sicca syndrome Sjogren syndrome 49,185
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019647/ScoringFiles/PGS019647.txt.gz
PGS019648
(TPMI_709.2_PRS-CS)
PGP000835 |
Chen HH et al. Nature (2025)
Sicca syndrome Sjogren syndrome 983,765
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019648/ScoringFiles/PGS019648.txt.gz
PGS019649
(TPMI_709.2_PRSmix+)
PGP000835 |
Chen HH et al. Nature (2025)
Sicca syndrome Sjogren syndrome 1,071,405
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019649/ScoringFiles/PGS019649.txt.gz
PGS019650
(TPMI_709.2_SBayesR)
PGP000835 |
Chen HH et al. Nature (2025)
Sicca syndrome Sjogren syndrome 202,225
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019650/ScoringFiles/PGS019650.txt.gz
PGS019651
(TPMI_709.7_Lassosum2)
PGP000835 |
Chen HH et al. Nature (2025)
Unspecified diffuse connective tissue disease connective tissue disorder 229
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019651/ScoringFiles/PGS019651.txt.gz
PGS019652
(TPMI_709.7_LDpred2)
PGP000835 |
Chen HH et al. Nature (2025)
Unspecified diffuse connective tissue disease connective tissue disorder 939,877
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019652/ScoringFiles/PGS019652.txt.gz
PGS019653
(TPMI_709.7_MegaPRS)
PGP000835 |
Chen HH et al. Nature (2025)
Unspecified diffuse connective tissue disease connective tissue disorder 26,844
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019653/ScoringFiles/PGS019653.txt.gz
PGS019654
(TPMI_709.7_PRS-CS)
PGP000835 |
Chen HH et al. Nature (2025)
Unspecified diffuse connective tissue disease connective tissue disorder 983,816
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019654/ScoringFiles/PGS019654.txt.gz
PGS019655
(TPMI_709.7_SBayesR)
PGP000835 |
Chen HH et al. Nature (2025)
Unspecified diffuse connective tissue disease connective tissue disorder 978,053
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019655/ScoringFiles/PGS019655.txt.gz
PGS019656
(TPMI_714_Lassosum2)
PGP000835 |
Chen HH et al. Nature (2025)
Rheumatoid arthritis and other inflammatory polyarthropathies rheumatoid arthritis 1,304
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019656/ScoringFiles/PGS019656.txt.gz
PGS019657
(TPMI_714_LDpred2)
PGP000835 |
Chen HH et al. Nature (2025)
Rheumatoid arthritis and other inflammatory polyarthropathies rheumatoid arthritis 939,829
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019657/ScoringFiles/PGS019657.txt.gz
PGS019658
(TPMI_714_MegaPRS)
PGP000835 |
Chen HH et al. Nature (2025)
Rheumatoid arthritis and other inflammatory polyarthropathies rheumatoid arthritis 28,836
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019658/ScoringFiles/PGS019658.txt.gz
PGS019659
(TPMI_714_PRS-CS)
PGP000835 |
Chen HH et al. Nature (2025)
Rheumatoid arthritis and other inflammatory polyarthropathies rheumatoid arthritis 983,784
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019659/ScoringFiles/PGS019659.txt.gz
PGS019660
(TPMI_714_SBayesR)
PGP000835 |
Chen HH et al. Nature (2025)
Rheumatoid arthritis and other inflammatory polyarthropathies rheumatoid arthritis 554,495
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019660/ScoringFiles/PGS019660.txt.gz
PGS019661
(TPMI_714.1_Lassosum2)
PGP000835 |
Chen HH et al. Nature (2025)
Rheumatoid arthritis rheumatoid arthritis 2,493
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019661/ScoringFiles/PGS019661.txt.gz
PGS019662
(TPMI_714.1_LDpred2)
PGP000835 |
Chen HH et al. Nature (2025)
Rheumatoid arthritis rheumatoid arthritis 939,827
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019662/ScoringFiles/PGS019662.txt.gz
PGS019663
(TPMI_714.1_MegaPRS)
PGP000835 |
Chen HH et al. Nature (2025)
Rheumatoid arthritis rheumatoid arthritis 33,790
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019663/ScoringFiles/PGS019663.txt.gz
PGS019664
(TPMI_714.1_PRS-CS)
PGP000835 |
Chen HH et al. Nature (2025)
Rheumatoid arthritis rheumatoid arthritis 983,784
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019664/ScoringFiles/PGS019664.txt.gz
PGS019665
(TPMI_714.1_SBayesR)
PGP000835 |
Chen HH et al. Nature (2025)
Rheumatoid arthritis rheumatoid arthritis 913,921
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019665/ScoringFiles/PGS019665.txt.gz
PGS019666
(TPMI_715_Lassosum2)
PGP000835 |
Chen HH et al. Nature (2025)
Other inflammatory spondylopathies inflammatory spondylopathy 27
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019666/ScoringFiles/PGS019666.txt.gz
PGS019667
(TPMI_715_LDpred2)
PGP000835 |
Chen HH et al. Nature (2025)
Other inflammatory spondylopathies inflammatory spondylopathy 939,889
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019667/ScoringFiles/PGS019667.txt.gz
PGS019668
(TPMI_715_MegaPRS)
PGP000835 |
Chen HH et al. Nature (2025)
Other inflammatory spondylopathies inflammatory spondylopathy 294,406
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019668/ScoringFiles/PGS019668.txt.gz