Polygenic Scores (PGS)

Filter PGS by Participant Ancestry
Individuals included in:
G - Source of Variant Associations (GWAS)
D - Score Development/Training
E - PGS Evaluation
List of ancestries includes:
Display options:
Ancestry legend
Multi-ancestry (including European)
Multi-ancestry (excluding European)
African
East Asian
South Asian
Additional Asian Ancestries
European
Greater Middle Eastern
Hispanic or Latin American
Additional Diverse Ancestries
Not Reported
Polygenic Score ID & Name PGS Publication ID (PGP) Reported Trait Mapped Trait(s) (Ontology) Number of Variants Ancestry distribution
GWAS
Dev
Eval
 Scoring File (FTP Link)
PGS000326
(GRS-JIA-RFN-20)
 PGP000052 |
Cánovas R et al. Ann Rheum Dis (2020)
 Rheumatoid-factor-negative Polyarthritis (Juvenile Idiophatic Arthritis) rheumatoid factor-negative juvenile idiopathic arthritis 12
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000326/ScoringFiles/PGS000326.txt.gz
PGS000350
(GRS12_POAG)
 PGP000115 |
Fan BJ et al. JAMA Ophthalmol (2019)
 Primary open-angle glaucoma open-angle glaucoma 12
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000350/ScoringFiles/PGS000350.txt.gz
PGS000381
(PRSWEB_PHECODE153.2_UKBB-SAIGE-HRC-X153.2_PT_MGI_20200608)
 PGP000118 |
Fritsche LG et al. Am J Hum Genet (2020)
 Colon cancer colon carcinoma 12
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000381/ScoringFiles/PGS000381.txt.gz
PGS000429
(PRSWEB_PHECODE172.1_UKBB-SAIGE-HRC-X172.1_P_5e-08_MGI_20200608)
 PGP000118 |
Fritsche LG et al. Am J Hum Genet (2020)
 Melanomas of skin (diagnosis or history) melanoma 12
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000429/ScoringFiles/PGS000429.txt.gz
PGS000551
(PRSWEB_PHECODE184.11_Phelan-IEOC_PT_UKB_20200608)
 PGP000118 |
Fritsche LG et al. Am J Hum Genet (2020)
 Malignant neoplasm of ovary ovarian neoplasm 12
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000551/ScoringFiles/PGS000551.txt.gz
PGS000563
(PRSWEB_PHECODE184.11_Phelan-SIOC_PT_UKB_20200608)
 PGP000118 |
Fritsche LG et al. Am J Hum Genet (2020)
 Malignant neoplasm of ovary ovarian neoplasm 12
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000563/ScoringFiles/PGS000563.txt.gz
PGS000605
(PRSWEB_PHECODE189.11_GWAS-Catalog-r2019-05-03-X189.11_P_5e-08_UKB_20200608)
 PGP000118 |
Fritsche LG et al. Am J Hum Genet (2020)
 Malignant neoplasm of kidney, except pelvis kidney cancer 12
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000605/ScoringFiles/PGS000605.txt.gz
PGS000606
(PRSWEB_PHECODE189.11_GWAS-Catalog-r2019-05-03-X189.11_PT_UKB_20200608)
 PGP000118 |
Fritsche LG et al. Am J Hum Genet (2020)
 Malignant neoplasm of kidney, except pelvis kidney cancer 12
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000606/ScoringFiles/PGS000606.txt.gz
PGS000621
(PRSWEB_PHECODE191.11_GWAS-Catalog-r2019-05-03-X191.11_P_5e-08_MGI_20200608)
 PGP000118 |
Fritsche LG et al. Am J Hum Genet (2020)
 Brain cancer brain cancer 12
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000621/ScoringFiles/PGS000621.txt.gz
PGS000622
(PRSWEB_PHECODE191.11_GWAS-Catalog-r2019-05-03-X191.11_P_5e-08_UKB_20200608)
 PGP000118 |
Fritsche LG et al. Am J Hum Genet (2020)
 Brain cancer brain cancer 12
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000622/ScoringFiles/PGS000622.txt.gz
PGS000641
(PRSWEB_PHECODE202.2_GWAS-Catalog-r2019-05-03-X202.2_P_5e-08_UKB_20200608)
 PGP000118 |
Fritsche LG et al. Am J Hum Genet (2020)
 Non-Hodgkin's lymphoma non-Hodgkin lymphoma 12
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000641/ScoringFiles/PGS000641.txt.gz
PGS000726
(PGS12_CIR)
 PGP000136 |
Emdin CA et al. Gastroenterology (2020)
 Cirrhosis cirrhosis of liver 12
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000726/ScoringFiles/PGS000726.txt.gz
PGS000797
(CC_Thyroid_IV)
 PGP000186 |
Kachuri L et al. Nat Commun (2020)
 Thyroid cancer thyroid gland carcinoma 12
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000797/ScoringFiles/PGS000797.txt.gz
PGS000922
(GBE_HC170)
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Sarcoidosis sarcoidosis 12
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000922/ScoringFiles/PGS000922.txt.gz
PGS001354
(PRS12_TC)
 PGP000251 |
Song N et al. Cancer Epidemiol Biomarkers Prev (2021)
 Thyroid cancer thyroid gland carcinoma 12
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001354/ScoringFiles/PGS001354.txt.gz
PGS001774
(PRS12_PD)
 PGP000254 |
Chairta PP et al. Genes (Basel) (2021)
 Parkinson's disease Parkinson disease 12
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001774/ScoringFiles/PGS001774.txt.gz
PGS002273
(GRS12_COVID)
 PGP000302 |
Horowitz JE et al. Nat Genet (2022)
 COVID-19 infection COVID-19 12
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002273/ScoringFiles/PGS002273.txt.gz
PGS002291
(PRS12_NPC)
 PGP000320 |
He YQ et al. Nat Commun (2022)
 Nasopharyngeal carcinoma nasopharyngeal neoplasm 12
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002291/ScoringFiles/PGS002291.txt.gz
PGS002585
(repro_ChildLess.P+T.5e-08)
 PGP000332 |
Weissbrod O et al. Nat Genet (2022)
 Childless reproductive behavior trait 12
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002585/ScoringFiles/PGS002585.txt.gz
PGS003594
(R_GC-ML-DG_body_trans_ancestry_meta_analysis)
 PGP000464 |
Liu N et al. Nat Genet (2023)
 Right granule cell and molecular layer of the dentate gyrus body volume dentate gyrus volume 12
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003594/ScoringFiles/PGS003594.txt.gz
PGS004241
(PRS12_bladder)
 PGP000542 |
Kim ES et al. NPJ Precis Oncol (2023)
 Bladder cancer urinary bladder carcinoma 12
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004241/ScoringFiles/PGS004241.txt.gz
PGS004245
(PRS12_kidney)
 PGP000542 |
Kim ES et al. NPJ Precis Oncol (2023)
 Kidney cancer renal cell carcinoma 12
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004245/ScoringFiles/PGS004245.txt.gz
PGS004598
(PRS12_HF)
 PGP000576 |
Peng H et al. Nutrients (2023)
 Heart failure heart failure 12
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004598/ScoringFiles/PGS004598.txt.gz
PGS004700
(HLA-GRS)
 PGP000603 |
Loginovic P et al. Nat Commun (2024)
 Multiple sclerosis multiple sclerosis 12
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004700/ScoringFiles/PGS004700.txt.gz
PGS004922
(wGRS_AFR)
 PGP000655 |
El-Boraie A et al. Clin Pharmacol Ther (2021)
 Nicotine metabolite ratio nicotine metabolite ratio 12
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004922/ScoringFiles/PGS004922.txt.gz
PGS005161
(PRS-GC)
 PGP000711 |
Zhu M et al. PLoS Med (2025)
 Stomach cancer gastric cancer 12
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005161/ScoringFiles/PGS005161.txt.gz
PGS005210
(Thyroid_PRS)
 PGP000729 |
Gibson TM et al. Nat Med (2024)
 Thyroid cancer thyroid gland carcinoma 12
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005210/ScoringFiles/PGS005210.txt.gz
PGS005319
(HF_PRS)
 PGP000766 |
Türkmen D et al. Pharmacogenomics J (2024)
 Heart failure heart failure 12
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005319/ScoringFiles/PGS005319.txt.gz
PGS018856
(TPMI_279_Lassosum2)
 PGP000835 |
Chen HH et al. Nature (2025)
 Disorders involving the immune mechanism Immunodeficiency 12
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018856/ScoringFiles/PGS018856.txt.gz
PGS019011
(TPMI_362_Lassosum2)
 PGP000835 |
Chen HH et al. Nature (2025)
 Other retinal disorders retinal disorder 12
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019011/ScoringFiles/PGS019011.txt.gz
PGS019954
(PRS12_GC)
 PGP000844 |
Xu HM et al. JAMA Netw Open (2024)
 Gastric Cancer gastric cancer 12
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019954/ScoringFiles/PGS019954.txt.gz
PGS000461
(PRSWEB_PHECODE172.22_GWAS-Catalog-r2019-05-03-X172.22_P_5e-08_MGI_20200608)
 PGP000118 |
Fritsche LG et al. Am J Hum Genet (2020)
 Squamous cell carcinoma squamous cell carcinoma 13
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000461/ScoringFiles/PGS000461.txt.gz
PGS000462
(PRSWEB_PHECODE172.22_GWAS-Catalog-r2019-05-03-X172.22_P_5e-08_UKB_20200608)
 PGP000118 |
Fritsche LG et al. Am J Hum Genet (2020)
 Squamous cell carcinoma squamous cell carcinoma 13
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000462/ScoringFiles/PGS000462.txt.gz
PGS000610
(PRSWEB_PHECODE189.2_GWAS-Catalog-r2019-05-03-X189.2_P_5e-08_MGI_20200608)
 PGP000118 |
Fritsche LG et al. Am J Hum Genet (2020)
 Bladder cancer urinary bladder carcinoma 13
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000610/ScoringFiles/PGS000610.txt.gz
PGS000611
(PRSWEB_PHECODE189.2_GWAS-Catalog-r2019-05-03-X189.2_P_5e-08_UKB_20200608)
 PGP000118 |
Fritsche LG et al. Am J Hum Genet (2020)
 Bladder cancer urinary bladder carcinoma 13
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000611/ScoringFiles/PGS000611.txt.gz
PGS000612
(PRSWEB_PHECODE189.2_GWAS-Catalog-r2019-05-03-X189.2_PT_MGI_20200608)
 PGP000118 |
Fritsche LG et al. Am J Hum Genet (2020)
 Bladder cancer urinary bladder carcinoma 13
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000612/ScoringFiles/PGS000612.txt.gz
PGS000897
(GLGC_2021_SAS_LDL_PRS_weights_PT)
 PGP000230 |
Graham SE et al. Nature (2021)
 LDL cholesterol low density lipoprotein cholesterol measurement 13
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000897/ScoringFiles/PGS000897.txt.gz
PGS002925
(ExPRSweb_FPG_FGovertime-corrected_PT_MGI_20211120)
 PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
 Fasting plasma glucose blood glucose amount 13
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002925/ScoringFiles/PGS002925.txt.gz
PGS002926
(ExPRSweb_FPG_FGovertime-corrected_PLINK_MGI_20211120)
 PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
 Fasting plasma glucose blood glucose amount 13
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002926/ScoringFiles/PGS002926.txt.gz
PGS003040
(ExPRSweb_PUFAs_MAGNETIC-otPUFA_PT_UKB_20211120)
 PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
 Polyunsatturated fatty acids polyunsaturated fatty acid measurement 13
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003040/ScoringFiles/PGS003040.txt.gz
PGS003041
(ExPRSweb_PUFAs_MAGNETIC-otPUFA_PLINK_UKB_20211120)
 PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
 Polyunsatturated fatty acids polyunsaturated fatty acid measurement 13
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003041/ScoringFiles/PGS003041.txt.gz
PGS003736
(PRS13_BlC)
 PGP000470 |
Xin J et al. EBioMedicine (2023)
 Bladder cancer urinary bladder cancer 13
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003736/ScoringFiles/PGS003736.txt.gz
PGS004108
(pt_clump.auto.GCST005838.Stroke)
 PGP000517 |
Monti R et al. Am J Hum Genet (2024)
 Stroke stroke disorder 13
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004108/ScoringFiles/PGS004108.txt.gz
PGS004222
(GRS13_gout)
 PGP000522 |
Wu Q et al. J Psychosom Res (2023)
 Gout gout 13
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004222/ScoringFiles/PGS004222.txt.gz
PGS012550
(PRS13_IPF)
 PGP000793 |
Tang L et al. Environ Res (2023)
 Idiopathic pulmonary fibrosis idiopathic pulmonary fibrosis 13
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS012550/ScoringFiles/PGS012550.txt.gz
PGS012582
(PRS13_cholelithiasis)
 PGP000816 |
Mi N et al. Prev Med (2024)
 Cholelithiasis cholelithiasis 13
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS012582/ScoringFiles/PGS012582.txt.gz
PGS019066
(TPMI_379_Lassosum2)
 PGP000835 |
Chen HH et al. Nature (2025)
 Other disorders of eye eye disorder 13
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019066/ScoringFiles/PGS019066.txt.gz
PGS000081
(CC_Oral)
 PGP000050 |
Graff RE et al. Nat Commun (2021)
 Oral cavity and pharyngeal cancers oral cavity cancer,
pharynx cancer		 14
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000081/ScoringFiles/PGS000081.txt.gz
PGS000151
(SC_GRS)
 PGP000074 |
Xin J et al. Gene (2018)
 Colorectal cancer colorectal cancer 14
-
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000151/ScoringFiles/PGS000151.txt.gz
PGS000353
(PRSWEB_PHECODE10001_UKBB-SAIGE-HRC-X10001_P_5e-08_MGI_20200608)
 PGP000118 |
Fritsche LG et al. Am J Hum Genet (2020)
 Any cancer cancer 14
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000353/ScoringFiles/PGS000353.txt.gz
Showing 201 to 250 of 6982 rows