Trait: fatty acid amount

Trait Information
Identifier OBA_VT0010046
Description The amount of a fatty acid when measured in anatomical entity. [AUTO: patterns/patterns/entity_attribute_location]
Trait category
Lipid or lipoprotein measurement
Synonym anatomical entity fatty acid amount
Child trait(s) 4 child traits

Associated Polygenic Score(s)

Filter PGS by Participant Ancestry
Individuals included in:
G - Source of Variant Associations (GWAS)
D - Score Development/Training
E - PGS Evaluation
List of ancestries includes:
Display options:
Ancestry legend
Multi-ancestry (including European)
Multi-ancestry (excluding European)
African
East Asian
South Asian
Additional Asian Ancestries
European
Greater Middle Eastern
Hispanic or Latin American
Additional Diverse Ancestries
Not Reported
Note: This table shows all PGS for "fatty acid amount" and any child terms of this trait in the EFO hierarchy by default.
Polygenic Score ID & Name PGS Publication ID (PGP) Reported Trait Mapped Trait(s) (Ontology) Number of Variants Ancestry distribution
GWAS
Dev
Eval
 Scoring File (FTP Link)
PGS003039
(ExPRSweb_PUFAs_MAGNETIC-otPUFA_LASSOSUM_UKB_20211120)
 PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
 Polyunsatturated fatty acids polyunsaturated fatty acid measurement 378,933
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003039/ScoringFiles/PGS003039.txt.gz
PGS003040
(ExPRSweb_PUFAs_MAGNETIC-otPUFA_PT_UKB_20211120)
 PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
 Polyunsatturated fatty acids polyunsaturated fatty acid measurement 13
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003040/ScoringFiles/PGS003040.txt.gz
PGS003041
(ExPRSweb_PUFAs_MAGNETIC-otPUFA_PLINK_UKB_20211120)
 PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
 Polyunsatturated fatty acids polyunsaturated fatty acid measurement 13
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003041/ScoringFiles/PGS003041.txt.gz
PGS003042
(ExPRSweb_PUFAs_MAGNETIC-otPUFA_DBSLMM_UKB_20211120)
 PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
 Polyunsatturated fatty acids polyunsaturated fatty acid measurement 272
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003042/ScoringFiles/PGS003042.txt.gz
PGS003043
(ExPRSweb_PUFAs_MAGNETIC-otPUFA_PRSCS_UKB_20211120)
 PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
 Polyunsatturated fatty acids polyunsaturated fatty acid measurement 1,116,151
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003043/ScoringFiles/PGS003043.txt.gz
PGS012565
(DHA_sBayesRC)
 PGP000809 |
Xu H et al. Clin Nutr (2026)
 Docosahexaenoic acid docosahexaenoic acid measurement 13,083,387
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS012565/ScoringFiles/PGS012565.txt.gz
PGS012566
(DHA_pct_sBayesRC)
 PGP000809 |
Xu H et al. Clin Nutr (2026)
 Docosahexaenoic acid to total fatty acids percentage docosahexaenoic acid to total fatty acids percentage 13,083,387
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS012566/ScoringFiles/PGS012566.txt.gz
PGS012567
(Omega_3_sBayesRC)
 PGP000809 |
Xu H et al. Clin Nutr (2026)
 Omega-3 fatty acids omega-3 polyunsaturated fatty acid measurement 13,083,387
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS012567/ScoringFiles/PGS012567.txt.gz
PGS012568
(Omega_3_pct_sBayesRC)
 PGP000809 |
Xu H et al. Clin Nutr (2026)
 Omega-3 fatty acids to total fatty acids percentage fatty acid amount 13,083,387
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS012568/ScoringFiles/PGS012568.txt.gz
PGS012569
(DHA_PplusT)
 PGP000809 |
Xu H et al. Clin Nutr (2026)
 Docosahexaenoic acid docosahexaenoic acid measurement 179
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS012569/ScoringFiles/PGS012569.txt.gz
PGS012570
(DHA_pct_PplusT)
 PGP000809 |
Xu H et al. Clin Nutr (2026)
 Docosahexaenoic acid to total fatty acids percentage docosahexaenoic acid to total fatty acids percentage 110
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS012570/ScoringFiles/PGS012570.txt.gz
PGS012571
(Omega_3_PplusT)
 PGP000809 |
Xu H et al. Clin Nutr (2026)
 Omega-3 fatty acids omega-3 polyunsaturated fatty acid measurement 214
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS012571/ScoringFiles/PGS012571.txt.gz
PGS012572
(Omega_3_pct_PplusT)
 PGP000809 |
Xu H et al. Clin Nutr (2026)
 Omega-3 fatty acids to total fatty acids percentage fatty acid amount 163
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS012572/ScoringFiles/PGS012572.txt.gz

Performance Metrics

Disclaimer: The performance metrics are displayed as reported by the source studies. It is important to note that metrics are not necessarily comparable with each other. For example, metrics depend on the sample characteristics (described by the PGS Catalog Sample Set [PSS] ID), phenotyping, and statistical modelling. Please refer to the source publication for additional guidance on performance.

PGS Performance
Metric ID (PPM) 		Evaluated Score PGS Sample Set ID
(PSS) 		Performance Source Trait PGS Effect Sizes
(per SD change) 		Classification Metrics Other Metrics Covariates Included in the Model PGS Performance:
Other Relevant Information
PPM015928 PGS003039
(ExPRSweb_PUFAs_MAGNETIC-otPUFA_LASSOSUM_UKB_20211120)
 PSS010031|
European Ancestry|
87,079 individuals
 PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
 Reported Trait: Polyunsatturated Fatty Acids β: -0.0238 (0.0247) — R²: 7.08e-06 Sex,birthYear,genotyping.array,PC1,PC2,PC3,PC4 —
PPM015931 PGS003040
(ExPRSweb_PUFAs_MAGNETIC-otPUFA_PT_UKB_20211120)
 PSS010031|
European Ancestry|
87,079 individuals
 PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
 Reported Trait: Polyunsatturated Fatty Acids β: -0.0246 (0.0248) — R²: 8.35e-06 Sex,birthYear,genotyping.array,PC1,PC2,PC3,PC4 —
PPM015929 PGS003041
(ExPRSweb_PUFAs_MAGNETIC-otPUFA_PLINK_UKB_20211120)
 PSS010031|
European Ancestry|
87,079 individuals
 PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
 Reported Trait: Polyunsatturated Fatty Acids β: -0.0127 (0.0247) — R²: 2.06e-06 Sex,birthYear,genotyping.array,PC1,PC2,PC3,PC4 —
PPM015927 PGS003042
(ExPRSweb_PUFAs_MAGNETIC-otPUFA_DBSLMM_UKB_20211120)
 PSS010031|
European Ancestry|
87,079 individuals
 PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
 Reported Trait: Polyunsatturated Fatty Acids β: -0.0204 (0.0248) — R²: 9.79e-06 Sex,birthYear,genotyping.array,PC1,PC2,PC3,PC4 —
PPM015930 PGS003043
(ExPRSweb_PUFAs_MAGNETIC-otPUFA_PRSCS_UKB_20211120)
 PSS010031|
European Ancestry|
87,079 individuals
 PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
 Reported Trait: Polyunsatturated Fatty Acids β: -0.00329 (0.0248) — R²: 2.41e-07 Sex,birthYear,genotyping.array,PC1,PC2,PC3,PC4 —
PPM030712 PGS012565
(DHA_sBayesRC)
 PSS012262|
Multi-ancestry (including European)|
433,446 individuals
 PGP000809 |
Xu H et al. Clin Nutr (2026)
 Reported Trait: Circulating level of docosahexaenoic acid β: 0.24415 — R²: 0.07802 sex, age when attended assessment centre, interaction between sex and age, body mass index (BMI), Townsend index (TSI), smoking status, alcohol drinking status, physical activity, and statin use —
PPM030713 PGS012566
(DHA_pct_sBayesRC)
 PSS012262|
Multi-ancestry (including European)|
433,446 individuals
 PGP000809 |
Xu H et al. Clin Nutr (2026)
 Reported Trait: Circulating level of docosahexaenoic acid totTotal fatty acids percentage β: 0.19824 — R²: 0.05337 sex, age when attended assessment centre, interaction between sex and age, body mass index (BMI), Townsend index (TSI), smoking status, alcohol drinking status, physical activity, and statin use —
PPM030714 PGS012567
(Omega_3_sBayesRC)
 PSS012262|
Multi-ancestry (including European)|
433,446 individuals
 PGP000809 |
Xu H et al. Clin Nutr (2026)
 Reported Trait: Circulating level of omega-3 fatty acids β: 0.30328 — R²: 0.11093 sex, age when attended assessment centre, interaction between sex and age, body mass index (BMI), Townsend index (TSI), smoking status, alcohol drinking status, physical activity, and statin use —
PPM030715 PGS012568
(Omega_3_pct_sBayesRC)
 PSS012262|
Multi-ancestry (including European)|
433,446 individuals
 PGP000809 |
Xu H et al. Clin Nutr (2026)
 Reported Trait: Circulating level of omega-3 fatty acids to total fatty acids percentage β: 0.28245 — R²: 0.10352 sex, age when attended assessment centre, interaction between sex and age, body mass index (BMI), Townsend index (TSI), smoking status, alcohol drinking status, physical activity, and statin use —
PPM030716 PGS012569
(DHA_PplusT)
 PSS012262|
Multi-ancestry (including European)|
433,446 individuals
 PGP000809 |
Xu H et al. Clin Nutr (2026)
 Reported Trait: Circulating level of docosahexaenoic acid β: 0.23465 — R²: 0.05085 sex, age when attended assessment centre, interaction between sex and age, body mass index (BMI), Townsend index (TSI), smoking status, alcohol drinking status, physical activity, and statin use —
PPM030717 PGS012570
(DHA_pct_PplusT)
 PSS012262|
Multi-ancestry (including European)|
433,446 individuals
 PGP000809 |
Xu H et al. Clin Nutr (2026)
 Reported Trait: Circulating level of docosahexaenoic acid totTotal fatty acids percentage β: 0.18474 — R²: 0.03233 sex, age when attended assessment centre, interaction between sex and age, body mass index (BMI), Townsend index (TSI), smoking status, alcohol drinking status, physical activity, and statin use —
PPM030718 PGS012571
(Omega_3_PplusT)
 PSS012262|
Multi-ancestry (including European)|
433,446 individuals
 PGP000809 |
Xu H et al. Clin Nutr (2026)
 Reported Trait: Circulating level of omega-3 fatty acids β: 0.27961 — R²: 0.06678 sex, age when attended assessment centre, interaction between sex and age, body mass index (BMI), Townsend index (TSI), smoking status, alcohol drinking status, physical activity, and statin use —
PPM030719 PGS012572
(Omega_3_pct_PplusT)
 PSS012262|
Multi-ancestry (including European)|
433,446 individuals
 PGP000809 |
Xu H et al. Clin Nutr (2026)
 Reported Trait: Circulating level of omega-3 fatty acids to total fatty acids percentage β: 0.26668 — R²: 0.06499 sex, age when attended assessment centre, interaction between sex and age, body mass index (BMI), Townsend index (TSI), smoking status, alcohol drinking status, physical activity, and statin use —

Evaluated Samples

PGS Sample Set ID
(PSS) 		Phenotype Definitions and Methods Participant Follow-up Time Sample Numbers Age of Study Participants Sample Ancestry Additional Ancestry Description Cohort(s) Additional Sample/Cohort Information
PSS012262 — — 416,315 individuals — European — UKB —
PSS012262 — — 2,571 individuals — East Asian — UKB —
PSS012262 — — 8,237 individuals — Central Asian, South Asian — UKB —
PSS010031 Field ID: 100007; Quantitative — 87,079 individuals — European — UKB —
PSS012262 — — 6,323 individuals — African unspecified — UKB —