Polygenic Scores (PGS)

Filter PGS by Participant Ancestry
Individuals included in:
G - Source of Variant Associations (GWAS)
D - Score Development/Training
E - PGS Evaluation
List of ancestries includes:
Display options:
Ancestry legend
Multi-ancestry (including European)
Multi-ancestry (excluding European)
African
East Asian
South Asian
Additional Asian Ancestries
European
Greater Middle Eastern
Hispanic or Latin American
Additional Diverse Ancestries
Not Reported
Polygenic Score ID & Name PGS Publication ID (PGP) Reported Trait Mapped Trait(s) (Ontology) Number of Variants Ancestry distribution
GWAS
Dev
Eval
 Scoring File (FTP Link)
PGS000924
(GBE_HC702)
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Disorders of porphyrin and bilirubin metabolism (time-to-event) bilirubin metabolism disease,
porphyrin metabolism disease		 5
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000924/ScoringFiles/PGS000924.txt.gz
PGS000943
(GBE_HC1126)
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Cholecystitis (time-to-event) Cholecystitis 5
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000943/ScoringFiles/PGS000943.txt.gz
PGS001011
(GBE_HC534)
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Viral warts (time-to-event) common wart 5
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001011/ScoringFiles/PGS001011.txt.gz
PGS001045
(GBE_BIN_FC6006155)
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Vitamin B9 intake vitamin supplement exposure measurement 5
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001045/ScoringFiles/PGS001045.txt.gz
PGS001065
(GBE_BIN_FC3006144)
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Never eat wheat diet measurement 5
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001065/ScoringFiles/PGS001065.txt.gz
PGS001153
(GBE_BIN_FC18006155)
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Folic acid or folate (Vitamin B9) folic acid level 5
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001153/ScoringFiles/PGS001153.txt.gz
PGS001399
(GBE_INI23002)
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 GE / gI antigen for Varicella Zoster Virus Varicella zoster virus seropositivity 5
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001399/ScoringFiles/PGS001399.txt.gz
PGS001598
(GBE_INI25787)
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Volume of grey matter in Superior Frontal Gyrus (R) neuroimaging measurement,
superior frontal gyrus grey matter volume measurement		 5
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001598/ScoringFiles/PGS001598.txt.gz
PGS002875
(ExPRSweb_CRP_prot-a-670_PT_MGI_20211120)
 PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
 C-reactive protein C-reactive protein measurement 5
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002875/ScoringFiles/PGS002875.txt.gz
PGS002876
(ExPRSweb_CRP_prot-a-670_PLINK_MGI_20211120)
 PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
 C-reactive protein C-reactive protein measurement 5
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002876/ScoringFiles/PGS002876.txt.gz
PGS002885
(ExPRSweb_CRP_prot-a-670_PT_UKB_20211120)
 PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
 C-reactive protein C-reactive protein measurement 5
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002885/ScoringFiles/PGS002885.txt.gz
PGS002886
(ExPRSweb_CRP_prot-a-670_PLINK_UKB_20211120)
 PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
 C-reactive protein C-reactive protein measurement 5
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002886/ScoringFiles/PGS002886.txt.gz
PGS003180
(ExPRSweb_VitD_100021-raw_PT_MGI_20211120)
 PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
 Vitamin D vitamin D level 5
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003180/ScoringFiles/PGS003180.txt.gz
PGS003354
(SSNS-GRS)
 PGP000407 |
Downie ML et al. Pediatr Nephrol (2022)
 Childhood steroid-sensitive nephrotic syndrome nephrotic syndrome 5
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003354/ScoringFiles/PGS003354.txt.gz
PGS003454
(PRS5_DLBCL)
 PGP000448 |
Berndt SI et al. Leukemia (2022)
 Diffuse large B-cell lymphoma diffuse large B-cell lymphoma 5
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003454/ScoringFiles/PGS003454.txt.gz
PGS005117
(PGS_T2D_liver_lipid)
 PGP000701 |
Loesch DP et al. Nat Commun (2025)
 Type 2 diabetes (T2D) type 2 diabetes mellitus 5
-
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005117/ScoringFiles/PGS005117.txt.gz
PGS005118
(PGS_T2D_obesity)
 PGP000701 |
Loesch DP et al. Nat Commun (2025)
 Type 2 diabetes (T2D) type 2 diabetes mellitus 5
-
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005118/ScoringFiles/PGS005118.txt.gz
PGS018475
(TPMI_150_Lassosum2)
 PGP000835 |
Chen HH et al. Nature (2025)
 Esophageal cancer esophageal cancer 5
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018475/ScoringFiles/PGS018475.txt.gz
PGS018966
(TPMI_327.5_Lassosum2)
 PGP000835 |
Chen HH et al. Nature (2025)
 Parasomnia Parasomnia 5
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018966/ScoringFiles/PGS018966.txt.gz
PGS019682
(TPMI_716.1_Lassosum2)
 PGP000835 |
Chen HH et al. Nature (2025)
 Unspecified polyarthropathy or polyarthritis arthropathy 5
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019682/ScoringFiles/PGS019682.txt.gz
PGS000156
(cGRS_Lung)
 PGP000075 |
Shi Z et al. Cancer Med (2019)
 Lung cancer lung carcinoma 6
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000156/ScoringFiles/PGS000156.txt.gz
PGS000162
(cGRS_Thyroid)
 PGP000075 |
Shi Z et al. Cancer Med (2019)
 Thyroid cancer thyroid gland carcinoma 6
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000162/ScoringFiles/PGS000162.txt.gz
PGS000399
(PRSWEB_PHECODE172_20001-1003_PT_MGI_20200608)
 PGP000118 |
Fritsche LG et al. Am J Hum Genet (2020)
 Skin cancer skin carcinoma 6
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000399/ScoringFiles/PGS000399.txt.gz
PGS000467
(PRSWEB_PHECODE172.22_cSCC-Chahal_PT_MGI_20200608)
 PGP000118 |
Fritsche LG et al. Am J Hum Genet (2020)
 Squamous cell carcinoma squamous cell carcinoma 6
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000467/ScoringFiles/PGS000467.txt.gz
PGS000547
(PRSWEB_PHECODE184.11_Phelan-EPOC_P_5e-08_UKB_20200608)
 PGP000118 |
Fritsche LG et al. Am J Hum Genet (2020)
 Malignant neoplasm of ovary ovarian neoplasm 6
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000547/ScoringFiles/PGS000547.txt.gz
PGS000598
(PRSWEB_PHECODE187.2_C3-TESTIS_P_5e-08_MGI_20200608)
 PGP000118 |
Fritsche LG et al. Am J Hum Genet (2020)
 Malignant neoplasm of testis testicular cancer 6
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000598/ScoringFiles/PGS000598.txt.gz
PGS000645
(PRSWEB_PHECODE204.1_C-LYMPHOID-LEUKAEMIA_PT_MGI_20200608)
 PGP000118 |
Fritsche LG et al. Am J Hum Genet (2020)
 Lymphoid leukemia lymphoid leukemia 6
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000645/ScoringFiles/PGS000645.txt.gz
PGS000650
(PRSWEB_PHECODE204.12_UKBB-SAIGE-HRC-X204.12_PT_MGI_20200608)
 PGP000118 |
Fritsche LG et al. Am J Hum Genet (2020)
 Chronic lymphocytic leukemia B-cell chronic lymphocytic leukemia 6
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000650/ScoringFiles/PGS000650.txt.gz
PGS000848
(T2D_Adiposity)
 PGP000211 |
Aly DM et al. Nat Genet (2021)
 Type 2 diabetes (based on SNPs associated with adiposity) type 2 diabetes mellitus 6
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000848/ScoringFiles/PGS000848.txt.gz
PGS000858
(T2D_Proinsulin)
 PGP000211 |
Aly DM et al. Nat Genet (2021)
 Type 2 diabetes (based on SNPs associated with proinsulin levels) type 2 diabetes mellitus 6
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000858/ScoringFiles/PGS000858.txt.gz
PGS000914
(PRS6_EC)
 PGP000241 |
Wang M et al. Sci Rep (2021)
 Abnormal electrocardiogram Abnormal EKG 6
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000914/ScoringFiles/PGS000914.txt.gz
PGS000929
(GBE_HC1583)
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 All-cause dementia (algorithmically-defined) dementia 6
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000929/ScoringFiles/PGS000929.txt.gz
PGS001110
(GBE_HC1209)
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reactive arthropathies (time-to-event) reactive arthritis 6
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001110/ScoringFiles/PGS001110.txt.gz
PGS001275
(GBE_HC880)
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Other retinal disorders (time-to-event) retinal disorder 6
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001275/ScoringFiles/PGS001275.txt.gz
PGS001349
(GBE_HC807)
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Alzheimer's disease (time-to-event) Alzheimer disease 6
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001349/ScoringFiles/PGS001349.txt.gz
PGS001353
(PRS6_PD)
 PGP000250 |
Sia MW et al. Mov Disord (2021)
 Parkinson's disease Parkinson disease 6
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001353/ScoringFiles/PGS001353.txt.gz
PGS002272
(GRS6_COVID)
 PGP000302 |
Horowitz JE et al. Nat Genet (2022)
 COVID-19 infection COVID-19 6
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002272/ScoringFiles/PGS002272.txt.gz
PGS002304
(PRS6_FL)
 PGP000328 |
Choi J et al. Int J Cancer (2020)
 Follicular lymphoma follicular lymphoma 6
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002304/ScoringFiles/PGS002304.txt.gz
PGS003310
(ExPRSweb_CysC_eGFRcys-overall-EA_PT_UKB_20211120)
 PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
 Estimated glomerular filtration rate (Cystatin C) cystatin C measurement,
glomerular filtration rate		 6
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003310/ScoringFiles/PGS003310.txt.gz
PGS003686
(L_molecular_layer_HP_body_UKBB_EUR_GWAS)
 PGP000464 |
Liu N et al. Nat Genet (2023)
 Left molecular layer hippocampus proper body volume hippocampus molecular layer volume 6
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003686/ScoringFiles/PGS003686.txt.gz
PGS003858
(GRS6_BMIadj)
 PGP000496 |
Sofer T et al. EBioMedicine (2023)
 Obstructive sleep apnea (BMI adjusted) obstructive sleep apnea syndrome 6
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003858/ScoringFiles/PGS003858.txt.gz
PGS005249
(PGS5_QBB_6SNP)
 PGP000743 |
Ismail Umlai UK et al. J Lipid Res (2025)
 LDL-C levels low density lipoprotein cholesterol measurement 6
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005249/ScoringFiles/PGS005249.txt.gz
PGS012521
(OSA_bmi_adj)
 PGP000786 |
Huang YJ et al. Nat Commun (2026)
 Obstructive sleep apnea (adjusted for BMI) obstructive sleep apnea syndrome 6
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS012521/ScoringFiles/PGS012521.txt.gz
PGS018595
(TPMI_198_Lassosum2)
 PGP000835 |
Chen HH et al. Nature (2025)
 Secondary malignant neoplasm secondary malignant neoplasm 6
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018595/ScoringFiles/PGS018595.txt.gz
PGS000023
(AA_GRS)
 PGP000013 |
Onengut-Gumuscu S et al. Diabetes Care (2019)
 Type 1 diabetes (T1D) type 1 diabetes mellitus 7
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000023/ScoringFiles/PGS000023.txt.gz
PGS000315
(GRS7_lgE)
 PGP000092 |
Xie T et al. Circ Genom Precis Med (2020)
 Immunoglobulin E (IgE) serum IgE amount 7
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000315/ScoringFiles/PGS000315.txt.gz
PGS000410
(PRSWEB_PHECODE172.1_20001-1059_PT_MGI_20200608)
 PGP000118 |
Fritsche LG et al. Am J Hum Genet (2020)
 Melanomas of skin (diagnosis or history) melanoma 7
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000410/ScoringFiles/PGS000410.txt.gz
PGS000463
(PRSWEB_PHECODE172.22_GWAS-Catalog-r2019-05-03-X172.22_PT_MGI_20200608)
 PGP000118 |
Fritsche LG et al. Am J Hum Genet (2020)
 Squamous cell carcinoma squamous cell carcinoma 7
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000463/ScoringFiles/PGS000463.txt.gz
PGS000471
(PRSWEB_PHECODE172.3_UKBB-SAIGE-HRC-X172.3_LASSOSUM_MGI_20200608)
 PGP000118 |
Fritsche LG et al. Am J Hum Genet (2020)
 Carcinoma in situ of skin skin carcinoma in situ 7
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000471/ScoringFiles/PGS000471.txt.gz
PGS000664
(GRS7_GFR)
 PGP000124 |
Gorski M et al. Kidney Int (2020)
 Rapid decline of glomerular filtration rate (GFR) GFR change measurement 7
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000664/ScoringFiles/PGS000664.txt.gz
Showing 51 to 100 of 6982 rows