| PGS Publication/Study ID (PGP) | PGS Developed | PGS Evaluated | First Author | Title | Journal Name | Publication Date | Digital object identifier (doi) | PubMed ID (PMID) |
|---|---|---|---|---|---|---|---|---|
| PGP000095 | 2 | 2 | Meisner A | Combined Utility of 25 Disease and Risk Factor Polygenic Risk Scores for Stratifying Risk of All-Cause Mortality. | Am J Hum Genet | 26/07/2020 | 10.1016/j.ajhg.2020.07.002 | 32758451 |
| PGP000055 | 3 | 3 | Fritsche LG | Exploring various polygenic risk scores for skin cancer in the phenomes of the Michigan genomics initiative and the UK Biobank with a visual catalog: PRSWeb. | PLoS Genet | 13/06/2019 | 10.1371/journal.pgen.1008202 | 31194742 |
| PGP000028 | 1 | 1 | Abraham G | Accurate and robust genomic prediction of celiac disease using statistical learning. | PLoS Genet | 13/02/2014 | 10.1371/journal.pgen.1004137 | 24550740 |
| PGP000029 | 2 | 3 | Abraham G | Genomic prediction of celiac disease targeting HLA-positive individuals. | Genome Med | 16/07/2015 | 10.1186/s13073-015-0196-5 | 26244058 |
| PGP000068 | 8 | 8 | Cai N | Minimal phenotyping yields genome-wide association signals of low specificity for major depression. | Nat Genet | 30/03/2020 | 10.1038/s41588-020-0594-5 | 32231276 |
| PGP000072 | 1 | 1 | Smith T | The added value of genetic information in colorectal cancer risk prediction models: development and evaluation in the UK Biobank prospective cohort study. | Br J Cancer | 16/10/2018 | 10.1038/s41416-018-0282-8 | 30323197 |
| PGP000004 | 1 | 2 | Tada H | Risk prediction by genetic risk scores for coronary heart disease is independent of self-reported family history. | Eur Heart J | 20/09/2015 | 10.1093/eurheartj/ehv462 | 26392438 |
| PGP000005 | 1 | 2 | Abraham G | Genomic prediction of coronary heart disease. | Eur Heart J | 21/09/2016 | 10.1093/eurheartj/ehw450 | 27655226 |
| PGP000069 | 1 | 1 | Hsu L | A model to determine colorectal cancer risk using common genetic susceptibility loci. | Gastroenterology | 13/02/2015 | 10.1053/j.gastro.2015.02.010 | 25683114 |
| PGP000070 | 1 | 1 | Ibáñez-Sanz G | Risk Model for Colorectal Cancer in Spanish Population Using Environmental and Genetic Factors: Results from the MCC-Spain study. | Sci Rep | 24/02/2017 | 10.1038/srep43263 | 28233817 |
| PGP000071 | 1 | 1 | Jeon J | Determining Risk of Colorectal Cancer and Starting Age of Screening Based on Lifestyle, Environmental, and Genetic Factors. | Gastroenterology | 17/02/2018 | 10.1053/j.gastro.2018.02.021 | 29458155 |
| PGP000088 | 5 | 7 | Zhang H | Genome-wide association study identifies 32 novel breast cancer susceptibility loci from overall and subtype-specific analyses. | Nat Genet | 18/05/2020 | 10.1038/s41588-020-0609-2 | 32424353 |
| PGP000073 | 1 | 1 | Weigl K | Genetic Risk Score Is Associated With Prevalence of Advanced Neoplasms in a Colorectal Cancer Screening Population. | Gastroenterology | 21/03/2018 | 10.1053/j.gastro.2018.03.030 | 29574091 |
| PGP000075 | 11 | 11 | Shi Z | Systematic evaluation of cancer-specific genetic risk score for 11 types of cancer in The Cancer Genome Atlas and Electronic Medical Records and Genomics cohorts. | Cancer Med | 09/04/2019 | 10.1002/cam4.2143 | 30968590 |
| PGP000058 | 0 | 1 | Huynh-Le M | Polygenic hazard score predicts aggressive and fatal prostate cancer in multi-ethnic populations | medRxivPre | 19/11/2019 | 10.1101/19012237 | — |
| PGP000030 | 1 | 1 | Klarin D | Genome-wide association analysis of venous thromboembolism identifies new risk loci and genetic overlap with arterial vascular disease. | Nat Genet | 01/11/2019 | 10.1038/s41588-019-0519-3 | 31676865 |
| PGP000031 | 1 | 1 | Pashayan N | Reducing overdiagnosis by polygenic risk-stratified screening: findings from the Finnish section of the ERSPC. | Br J Cancer | 20/08/2015 | 10.1038/bjc.2015.289 | 26291059 |
| PGP000032 | 0 | 1 | Pashayan N | Implications of polygenic risk-stratified screening for prostate cancer on overdiagnosis. | Genet Med | 08/01/2015 | 10.1038/gim.2014.192 | 25569441 |
| PGP000033 | 4 | 7 | Kuchenbaecker KB | Evaluation of Polygenic Risk Scores for Breast and Ovarian Cancer Risk Prediction in BRCA1 and BRCA2 Mutation Carriers. | J Natl Cancer Inst | 01/07/2017 | 10.1093/jnci/djw302 | 28376175 |
| PGP000034 | 1 | 4 | Lecarpentier J | Prediction of Breast and Prostate Cancer Risks in Male BRCA1 and BRCA2 Mutation Carriers Using Polygenic Risk Scores. | J Clin Oncol | 27/04/2017 | 10.1200/JCO.2016.69.4935 | 28448241 |
| PGP000096 | 1 | 1 | Chami N | The role of polygenic susceptibility to obesity among carriers of pathogenic mutations in MC4R in the UK Biobank population. | PLoS Med | 21/07/2020 | 10.1371/journal.pmed.1003196 | 32692746 |
| PGP000098 | 1 | 1 | Grove J | Identification of common genetic risk variants for autism spectrum disorder. | Nat Genet | 25/02/2019 | 10.1038/s41588-019-0344-8 | 30804558 |
| PGP000103 | 1 | 1 | Maukonen M | Genetic Associations of Chronotype in the Finnish General Population. | J Biol Rhythms | 24/06/2020 | 10.1177/0748730420935328 | 32579418 |
| PGP000104 | 1 | 1 | Koyama S | Population-specific and trans-ancestry genome-wide analyses identify distinct and shared genetic risk loci for coronary artery disease. | Nat Genet | 05/10/2020 | 10.1038/s41588-020-0705-3 | 33020668 |
| PGP000105 | 1 | 1 | Kloosterman M | Genetic risk and atrial fibrillation in patients with heart failure. | Eur J Heart Fail | 09/01/2020 | 10.1002/ejhf.1735 | 31919934 |
| PGP000117 | 2 | 5 | Barnes DR | Polygenic risk scores and breast and epithelial ovarian cancer risks for carriers of BRCA1 and BRCA2 pathogenic variants. | Genet Med | 15/07/2020 | 10.1038/s41436-020-0862-x | 32665703 |
| PGP000035 | 1 | 1 | Wen W | Prediction of breast cancer risk based on common genetic variants in women of East Asian ancestry. | Breast Cancer Res | 08/12/2016 | 10.1186/s13058-016-0786-1 | 27931260 |
| PGP000036 | 1 | 1 | Zhang X | Addition of a polygenic risk score, mammographic density, and endogenous hormones to existing breast cancer risk prediction models: A nested case-control study. | PLoS Med | 04/09/2018 | 10.1371/journal.pmed.1002644 | 30180161 |
| PGP000037 | 1 | 1 | Lakeman IMM | Addition of a 161-SNP polygenic risk score to family history-based risk prediction: impact on clinical management in non-BRCA1/2 breast cancer families. | J Med Genet | 11/06/2019 | 10.1136/jmedgenet-2019-106072 | 31186341 |
| PGP000079 | 1 | 1 | Kathiresan S | Polymorphisms associated with cholesterol and risk of cardiovascular events. | N Engl J Med | 01/03/2008 | 10.1056/nejmoa0706728 | 18354102 |
| PGS000080 | 1 | 1 | Coleman JRI | Genome-wide gene-environment analyses of major depressive disorder and reported lifetime traumatic experiences in UK Biobank. | Mol Psychiatry | 23/01/2020 | 10.1038/s41380-019-0546-6 | 31969693 |
| PGP000009 | 1 | 1 | Paquette M | Polygenic risk score predicts prevalence of cardiovascular disease in patients with familial hypercholesterolemia. | J Clin Lipidol | 06/04/2017 | 10.1016/j.jacl.2017.03.019 | 28456682 |
| PGP000010 | 1 | 1 | Läll K | Personalized risk prediction for type 2 diabetes: the potential of genetic risk scores. | Genet Med | 11/08/2016 | 10.1038/gim.2016.103 | 27513194 |
| PGP000112 | 4 | 4 | Ho WK | European polygenic risk score for prediction of breast cancer shows similar performance in Asian women. | Nat Commun | 31/07/2020 | 10.1038/s41467-020-17680-w | 32737321 |
| PGP000097 | 3 | 3 | Flynn E | Sex-specific genetic effects across biomarkers. | Eur J Hum Genet | 01/09/2020 | 10.1038/s41431-020-00712-w | 32873964 |
| PGP000011 | 1 | 1 | Oram RA | A Type 1 Diabetes Genetic Risk Score Can Aid Discrimination Between Type 1 and Type 2 Diabetes in Young Adults. | Diabetes Care | 17/11/2015 | 10.2337/dc15-1111 | 26577414 |
| PGP000041 | 1 | 1 | Paul KC | Association of Polygenic Risk Score With Cognitive Decline and Motor Progression in Parkinson Disease. | JAMA Neurol | 01/03/2018 | 10.1001/jamaneurol.2017.4206 | 29340614 |
| PGP000076 | 0 | 1 | Khera AV | Genetic Risk, Adherence to a Healthy Lifestyle, and Coronary Disease. | N Engl J Med | 13/11/2016 | 10.1056/NEJMoa1605086 | 27959714 |
| PGP000077 | 0 | 1 | Timmerman N | Family history and polygenic risk of cardiovascular disease: independent factors associated with secondary cardiovascular manifestations in patients undergoing carotid endarterectomy | medRxivPre | 18/09/2019 | 10.1101/19006718 | — |
| PGP000018 | 2 | 2 | Shieh Y | Breast cancer risk prediction using a clinical risk model and polygenic risk score. | Breast Cancer Res Treat | 26/08/2016 | 10.1007/s10549-016-3953-2 | 27565998 |
| PGP000106 | 1 | 1 | Law MH | Multiplex melanoma families are enriched for polygenic risk. | Hum Mol Genet | 01/10/2020 | 10.1093/hmg/ddaa156 | 32716505 |
| PGP000099 | 1 | 1 | Reid S | High genetic risk score is associated with early disease onset, damage accrual and decreased survival in systemic lupus erythematosus. | Ann Rheum Dis | 11/12/2019 | 10.1136/annrheumdis-2019-216227 | 31826855 |
| PGP000108 | 0 | 1 | Hindy G | Genome-Wide Polygenic Score, Clinical Risk Factors, and Long-Term Trajectories of Coronary Artery Disease. | Arterioscler Thromb Vasc Biol | 22/09/2020 | 10.1161/atvbaha.120.314856 | 32957805 |
| PGP000081 | 6 | 6 | Knevel R | Using genetics to prioritize diagnoses for rheumatology outpatients with inflammatory arthritis. | Sci Transl Med | 01/05/2020 | 10.1126/scitranslmed.aay1548 | 32461333 |
| PGP000001 | 3 | 3 | Mavaddat N | Prediction of breast cancer risk based on profiling with common genetic variants. | J Natl Cancer Inst | 08/04/2015 | 10.1093/jnci/djv036 | 25855707 |
| PGP000002 | 6 | 9 | Mavaddat N | Polygenic Risk Scores for Prediction of Breast Cancer and Breast Cancer Subtypes. | Am J Hum Genet | 13/12/2018 | 10.1016/j.ajhg.2018.11.002 | 30554720 |
| PGP000078 | 29 | 27 | Vuckovic D | The Polygenic and Monogenic Basis of Blood Traits and Diseases. | Cell | 01/09/2020 | 10.1016/j.cell.2020.08.008 | 32888494 |
| PGP000074 | 1 | 1 | Xin J | Evaluating the effect of multiple genetic risk score models on colorectal cancer risk prediction. | Gene | 14/06/2018 | 10.1016/j.gene.2018.06.035 | 29908285 |
| PGP000016 | 1 | 1 | Desikan RS | Genetic assessment of age-associated Alzheimer disease risk: Development and validation of a polygenic hazard score. | PLoS Med | 21/03/2017 | 10.1371/journal.pmed.1002258 | 28323831 |
| PGP000017 | 1 | 1 | Khera AV | Polygenic Prediction of Weight and Obesity Trajectories from Birth to Adulthood. | Cell | 01/04/2019 | 10.1016/j.cell.2019.03.028 | 31002795 |
| PGP000019 | 1 | 1 | Schumacher FR | Association analyses of more than 140,000 men identify 63 new prostate cancer susceptibility loci. | Nat Genet | 11/06/2018 | 10.1038/s41588-018-0142-8 | 29892016 |
| PGP000022 | 1 | 1 | Weng LC | Genetic Predisposition, Clinical Risk Factor Burden, and Lifetime Risk of Atrial Fibrillation. | Circulation | 12/11/2017 | 10.1161/CIRCULATIONAHA.117.031431 | 29129827 |
| PGP000100 | 5 | 5 | Mars N | Polygenic and clinical risk scores and their impact on age at onset and prediction of cardiometabolic diseases and common cancers. | Nat Med | 07/04/2020 | 10.1038/s41591-020-0800-0 | 32273609 |
| PGP000109 | 0 | 4 | Kramer I | Breast Cancer Polygenic Risk Score and Contralateral Breast Cancer Risk. | Am J Hum Genet | 05/10/2020 | 10.1016/j.ajhg.2020.09.001 | 33022221 |
| PGP000091 | 0 | 1 | Ferrat LA | A combined risk score enhances prediction of type 1 diabetes among susceptible children. | Nat Med | 07/08/2020 | 10.1038/s41591-020-0930-4 | 32770166 |
| PGP000090 | 1 | 2 | Wang M | Validation of a Genome-Wide Polygenic Score for Coronary Artery Disease in South Asians. | J Am Coll Cardiol | 01/08/2020 | 10.1016/j.jacc.2020.06.024 | 32762905 |
| PGP000107 | 1 | 1 | Trinder M | Polygenic Contribution to Low-Density Lipoprotein Cholesterol Levels and Cardiovascular Risk in Monogenic Familial Hypercholesterolemia. | Circ Genom Precis Med | 13/08/2020 | 10.1161/circgen.120.002919 | 33079599 |
| PGP000082 | 1 | 1 | Tikkanen E | Genetic risk prediction and a 2-stage risk screening strategy for coronary heart disease. | Arterioscler Thromb Vasc Biol | 18/04/2013 | 10.1161/atvbaha.112.301120 | 23599444 |
| PGP000003 | 1 | 1 | Mega JL | Genetic risk, coronary heart disease events, and the clinical benefit of statin therapy: an analysis of primary and secondary prevention trials. | Lancet | 04/03/2015 | 10.1016/S0140-6736(14)61730-X | 25748612 |
| PGP000101 | 1 | 1 | Zhang Q | Risk prediction of late-onset Alzheimer's disease implies an oligogenic architecture. | Nat Commun | 23/09/2020 | 10.1038/s41467-020-18534-1 | 32968074 |
| PGP000092 | 19 | 19 | Xie T | Genetic Risk Scores for Complex Disease Traits in Youth. | Circ Genom Precis Med | 11/06/2020 | 10.1161/circgen.119.002775 | 32527150 |
| PGP000083 | 0 | 4 | Dikilitas O | Predictive Utility of Polygenic Risk Scores for Coronary Heart Disease in Three Major Racial and Ethnic Groups. | Am J Hum Genet | 01/05/2020 | 10.1016/j.ajhg.2020.04.002 | 32386537 |
| PGP000119 | 2 | 2 | Namjou B | GWAS and enrichment analyses of non-alcoholic fatty liver disease identify new trait-associated genes and pathways across eMERGE Network. | BMC Med | 17/07/2019 | 10.1186/s12916-019-1364-z | 31311600 |
| PGP000093 | 1 | 1 | Sharp SA | A single nucleotide polymorphism genetic risk score to aid diagnosis of coeliac disease: a pilot study in clinical care. | Aliment Pharmacol Ther | 13/08/2020 | 10.1111/apt.15826 | 32790217 |
| PGP000084 | 6 | 6 | Barr PB | Using polygenic scores for identifying individuals at increased risk of substance use disorders in clinical and population samples. | Transl Psychiatry | 18/06/2020 | 10.1038/s41398-020-00865-8 | 32555147 |
| PGP000110 | 1 | 1 | Bossini-Castillo L | Genomic Risk Score impact on susceptibility to systemic sclerosis. | Ann Rheum Dis | 01/10/2020 | 10.1136/annrheumdis-2020-218558 | 33004331 |
| PGP000111 | 2 | 2 | Smith MP | Evaluation of a Genetic Risk Score for Diagnosis of Psoriatic Arthritis. | J Psoriasis Psoriatic Arthritis | 04/03/2020 | 10.1177/2475530320910814 | 32462110 |
| PGP000118 | 302 | 302 | Fritsche LG | Cancer PRSweb: An Online Repository with Polygenic Risk Scores for Major Cancer Traits and Their Evaluation in Two Independent Biobanks. | Am J Hum Genet | 28/09/2020 | 10.1016/j.ajhg.2020.08.025 | 32991828 |
| PGP000020 | 3 | 3 | Vassy JL | Polygenic type 2 diabetes prediction at the limit of common variant detection. | Diabetes | 11/02/2014 | 10.2337/db13-1663 | 24520119 |
| PGP000021 | 1 | 1 | Song M | Longitudinal Analysis of Genetic Susceptibility and BMI Throughout Adult Life. | Diabetes | 06/12/2017 | 10.2337/db17-1156 | 29212779 |
| PGP000094 | 1 | 1 | Shieh Y | A Polygenic Risk Score for Breast Cancer in US Latinas and Latin American Women. | J Natl Cancer Inst | 01/06/2020 | 10.1093/jnci/djz174 | 31553449 |
| PGP000006 | 5 | 5 | Khera AV | Genome-wide polygenic scores for common diseases identify individuals with risk equivalent to monogenic mutations. | Nat Genet | 13/08/2018 | 10.1038/s41588-018-0183-z | 30104762 |
| PGP000120 | 1 | 1 | Forgetta V | Development of a polygenic risk score to improve screening for fracture risk: A genetic risk prediction study. | PLoS Med | 02/07/2020 | 10.1371/journal.pmed.1003152 | 32614825 |
| PGP000023 | 1 | 0 | Mahajan A | Fine-mapping type 2 diabetes loci to single-variant resolution using high-density imputation and islet-specific epigenome maps. | Nat Genet | 08/10/2018 | 10.1038/s41588-018-0241-6 | 30297969 |
| PGP000024 | 0 | 1 | Udler MS | Genetic Risk Scores for Diabetes Diagnosis and Precision Medicine. | Endocr Rev | 01/12/2019 | 10.1210/er.2019-00088 | 31322649 |
| PGP000025 | 1 | 1 | Belsky DW | Polygenic risk and the development and course of asthma: an analysis of data from a four-decade longitudinal study. | Lancet Respir Med | 28/06/2013 | 10.1016/S2213-2600(13)70101-2 | 24429243 |
| PGP000008 | 0 | 2 | Wünnemann F | Validation of Genome-Wide Polygenic Risk Scores for Coronary Artery Disease in French Canadians. | Circ Genom Precis Med | 11/06/2019 | 10.1161/CIRCGEN.119.002481 | 31184202 |
| PGP000026 | 1 | 1 | Rutten-Jacobs LC | Genetic risk, incident stroke, and the benefits of adhering to a healthy lifestyle: cohort study of 306 473 UK Biobank participants. | BMJ | 24/10/2018 | 10.1136/bmj.k4168 | 30355576 |
| PGP000027 | 1 | 2 | Abraham G | Genomic risk score offers predictive performance comparable to clinical risk factors for ischaemic stroke. | Nat Commun | 20/12/2019 | 10.1038/s41467-019-13848-1 | 31862893 |
| PGP000015 | 1 | 1 | Chouraki V | Evaluation of a Genetic Risk Score to Improve Risk Prediction for Alzheimer's Disease. | J Alzheimers Dis | 01/06/2016 | 10.3233/JAD-150749 | 27340842 |
| PGP000063 | 1 | 1 | Tin A | Target genes, variants, tissues and transcriptional pathways influencing human serum urate levels. | Nat Genet | 02/10/2019 | 10.1038/s41588-019-0504-x | 31578528 |
| PGP000064 | 6 | 6 | Wheeler E | Impact of common genetic determinants of Hemoglobin A1c on type 2 diabetes risk and diagnosis in ancestrally diverse populations: A transethnic genome-wide meta-analysis. | PLoS Med | 12/09/2017 | 10.1371/journal.pmed.1002383 | 28898252 |
| PGP000309 | 1 | 1 | Bellenguez C | New insights into the genetic etiology of Alzheimer's disease and related dementias. | Nat Genet | 04/04/2022 | 10.1038/s41588-022-01024-z | 35379992 |
| PGP000066 | 1 | 1 | Craig JE | Multitrait analysis of glaucoma identifies new risk loci and enables polygenic prediction of disease susceptibility and progression. | Nat Genet | 20/01/2020 | 10.1038/s41588-019-0556-y | 31959993 |
| PGP000038 | 0 | 1 | Patel KA | Type 1 Diabetes Genetic Risk Score: A Novel Tool to Discriminate Monogenic and Type 1 Diabetes. | Diabetes | 05/04/2016 | 10.2337/db15-1690 | 27207547 |
| PGP000039 | 2 | 2 | Tosto G | Polygenic risk scores in familial Alzheimer disease. | Neurology | 17/02/2017 | 10.1212/WNL.0000000000003734 | 28213371 |
| PGP000040 | 1 | 1 | Schmit SL | Novel Common Genetic Susceptibility Loci for Colorectal Cancer. | J Natl Cancer Inst | 01/02/2019 | 10.1093/jnci/djy099 | 29917119 |
| PGP000042 | 1 | 1 | Natarajan P | Polygenic Risk Score Identifies Subgroup With Higher Burden of Atherosclerosis and Greater Relative Benefit From Statin Therapy in the Primary Prevention Setting. | Circulation | 21/02/2017 | 10.1161/CIRCULATIONAHA.116.024436 | 28223407 |
| PGP000043 | 1 | 1 | Morieri ML | Genetic Tools for Coronary Risk Assessment in Type 2 Diabetes: A Cohort Study From the ACCORD Clinical Trial. | Diabetes Care | 27/09/2018 | 10.2337/dc18-0709 | 30262460 |
| PGP000007 | 1 | 3 | Inouye M | Genomic Risk Prediction of Coronary Artery Disease in 480,000 Adults: Implications for Primary Prevention. | J Am Coll Cardiol | 01/10/2018 | 10.1016/j.jacc.2018.07.079 | 30309464 |
| PGP000012 | 1 | 1 | Perry DJ | Application of a Genetic Risk Score to Racially Diverse Type 1 Diabetes Populations Demonstrates the Need for Diversity in Risk-Modeling. | Sci Rep | 14/03/2018 | 10.1038/s41598-018-22574-5 | 29540798 |
| PGP000013 | 1 | 2 | Onengut-Gumuscu S | Type 1 Diabetes Risk in African-Ancestry Participants and Utility of an Ancestry-Specific Genetic Risk Score. | Diabetes Care | 18/01/2019 | 10.2337/dc18-1727 | 30659077 |
| PGP000044 | 1 | 1 | Hajek C | Coronary Heart Disease Genetic Risk Score Predicts Cardiovascular Disease Risk in Men, Not Women. | Circ Genom Precis Med | 01/10/2018 | 10.1161/CIRCGEN.118.002324 | 30354305 |
| PGP000045 | 4 | 4 | Johnson L | An Examination of the Relationship between Lipid Levels and Associated Genetic Markers across Racial/Ethnic Populations in the Multi-Ethnic Study of Atherosclerosis. | PLoS One | 07/05/2015 | 10.1371/journal.pone.0126361 | 25951326 |
| PGP000046 | 3 | 3 | Kuchenbaecker K | The transferability of lipid loci across African, Asian and European cohorts. | Nat Commun | 24/09/2019 | 10.1038/s41467-019-12026-7 | 31551420 |
| PGP000047 | 1 | 1 | Seibert TM | Polygenic hazard score to guide screening for aggressive prostate cancer: development and validation in large scale cohorts. | BMJ | 10/01/2018 | 10.1136/bmj.j5757 | 29321194 |
| PGP000048 | 2 | 2 | Yang X | Evaluation of polygenic risk scores for ovarian cancer risk prediction in a prospective cohort study. | J Med Genet | 05/05/2018 | 10.1136/jmedgenet-2018-105313 | 29730597 |
| PGP000085 | 3 | 3 | Liyanarachchi S | Assessing thyroid cancer risk using polygenic risk scores. | Proc Natl Acad Sci U S A | 04/03/2020 | 10.1073/pnas.1919976117 | 32132206 |
| PGP000014 | 1 | 2 | Sharp SA | Development and Standardization of an Improved Type 1 Diabetes Genetic Risk Score for Use in Newborn Screening and Incident Diagnosis. | Diabetes Care | 01/02/2019 | 10.2337/dc18-1785 | 30655379 |
| PGP000062 | 1 | 1 | Qi Q | Genetics of Type 2 Diabetes in U.S. Hispanic/Latino Individuals: Results From the Hispanic Community Health Study/Study of Latinos (HCHS/SOL). | Diabetes | 02/03/2017 | 10.2337/db16-1150 | 28254843 |
| PGP000086 | 1 | 1 | Shrine N | New genetic signals for lung function highlight pathways and chronic obstructive pulmonary disease associations across multiple ancestries. | Nat Genet | 25/02/2019 | 10.1038/s41588-018-0321-7 | 30804560 |
| PGP000113 | 1 | 1 | Black MH | Validation of a prostate cancer polygenic risk score. | Prostate | 17/08/2020 | 10.1002/pros.24058 | 33258481 |
| PGP000049 | 1 | 1 | Dai J | Identification of risk loci and a polygenic risk score for lung cancer: a large-scale prospective cohort study in Chinese populations. | Lancet Respir Med | 17/07/2019 | 10.1016/S2213-2600(19)30144-4 | 31326317 |
| PGP000114 | 1 | 1 | Pechlivanis S | Risk prediction for coronary heart disease by a genetic risk score - results from the Heinz Nixdorf Recall study. | BMC Med Genet | 10/09/2020 | 10.1186/s12881-020-01113-y | 32912153 |
| PGP000053 | 1 | 1 | Trinder M | Association of Monogenic vs Polygenic Hypercholesterolemia With Risk of Atherosclerotic Cardiovascular Disease. | JAMA Cardiol | 12/02/2020 | 10.1001/jamacardio.2019.5954 | 32049305 |
| PGP000054 | 2 | 2 | Elliott J | Predictive Accuracy of a Polygenic Risk Score-Enhanced Prediction Model vs a Clinical Risk Score for Coronary Artery Disease. | JAMA | 01/02/2020 | 10.1001/jama.2019.22241 | 32068818 |
| PGP000056 | 2 | 2 | Ho-Le TP | Prediction of Bone Mineral Density and Fragility Fracture by Genetic Profiling. | J Bone Miner Res | 26/10/2016 | 10.1002/jbmr.2998 | 27649491 |
| PGP000052 | 4 | 4 | Cánovas R | Genomic risk scores for juvenile idiopathic arthritis and its subtypes. | Ann Rheum Dis | 04/09/2020 | 10.1136/annrheumdis-2020-217421 | 32887683 |
| PGP000057 | 0 | 3 | Homburger JR | Low coverage whole genome sequencing enables accurate assessment of common variants and calculation of genome-wide polygenic scores. | Genome Med | 26/11/2019 | 10.1186/s13073-019-0682-2 | 31771638 |
| PGP000059 | 1 | 1 | Ibanez L | Parkinson disease polygenic risk score is associated with Parkinson disease status and age at onset but not with alpha-synuclein cerebrospinal fluid levels. | BMC Neurol | 15/11/2017 | 10.1186/s12883-017-0978-z | 29141588 |
| PGP000060 | 0 | 1 | Khera AV | Whole-Genome Sequencing to Characterize Monogenic and Polygenic Contributions in Patients Hospitalized With Early-Onset Myocardial Infarction. | Circulation | 01/03/2019 | 10.1161/circulationaha.118.035658 | 30586733 |
| PGP000115 | 1 | 1 | Fan BJ | Association of a Primary Open-Angle Glaucoma Genetic Risk Score With Earlier Age at Diagnosis. | JAMA Ophthalmol | 22/08/2019 | 10.1001/jamaophthalmol.2019.3109 | 31436842 |
| PGP000050 | 16 | 16 | Graff RE | Cross-cancer evaluation of polygenic risk scores for 16 cancer types in two large cohorts. | Nat Commun | 12/02/2021 | 10.1038/s41467-021-21288-z | 33579919 |
| PGP000061 | 1 | 1 | MacGregor S | Genome-wide association study of intraocular pressure uncovers new pathways to glaucoma. | Nat Genet | 27/07/2018 | 10.1038/s41588-018-0176-y | 30054594 |
| PGP000065 | 4 | 4 | Zheutlin AB | Penetrance and Pleiotropy of Polygenic Risk Scores for Schizophrenia in 106,160 Patients Across Four Health Care Systems. | Am J Psychiatry | 16/08/2019 | 10.1176/appi.ajp.2019.18091085 | 31416338 |
| PGP000087 | 1 | 1 | Pihlstrøm L | A cumulative genetic risk score predicts progression in Parkinson's disease. | Mov Disord | 08/02/2016 | 10.1002/mds.26505 | 26853697 |
| PGP000116 | 0 | 1 | Aragam KG | Limitations of Contemporary Guidelines for Managing Patients at High Genetic Risk of Coronary Artery Disease. | J Am Coll Cardiol | 01/06/2020 | 10.1016/j.jacc.2020.04.027 | 32498804 |
| PGP000102 | 1 | 3 | Mars N | The role of polygenic risk and susceptibility genes in breast cancer over the course of life | Nat Commun | 14/12/2020 | 10.1038/s41467-020-19966-5 | 33318493 |
| PGP000089 | 79 | 79 | Folkersen L | Genomic and drug target evaluation of 90 cardiovascular proteins in 30,931 individuals. | Nat Metab | 16/10/2020 | 10.1038/s42255-020-00287-2 | 33067605 |
| PGP000122 | 1 | 1 | Conti DV | Trans-ancestry genome-wide association meta-analysis of prostate cancer identifies new susceptibility loci and informs genetic risk prediction. | Nat Genet | 04/01/2021 | 10.1038/s41588-020-00748-0 | 33398198 |
| PGP000121 | 4 | 4 | Tam CHT | Development of genome-wide polygenic risk scores for lipid traits and clinical applications for dyslipidemia, subclinical atherosclerosis, and diabetes cardiovascular complications among East Asians. | Genome Med | 19/02/2021 | 10.1186/s13073-021-00831-z | 33608049 |
| PGP000189 | 2 | 2 | Dijk FN | Genetic risk scores do not improve asthma prediction in childhood. | J Allergy Clin Immunol | 27/05/2019 | 10.1016/j.jaci.2019.05.017 | 31145937 |
| PGP000190 | 1 | 1 | Hang D | Colorectal cancer susceptibility variants and risk of conventional adenomas and serrated polyps: results from three cohort studies. | Int J Epidemiol | 01/02/2020 | 10.1093/ije/dyz096 | 31038671 |
| PGP000126 | 1 | 1 | Pirruccello JP | Analysis of cardiac magnetic resonance imaging in 36,000 individuals yields genetic insights into dilated cardiomyopathy. | Nat Commun | 07/05/2020 | 10.1038/s41467-020-15823-7 | 32382064 |
| PGP000132 | 2 | 2 | Richardson TG | Use of genetic variation to separate the effects of early and later life adiposity on disease risk: mendelian randomisation study. | BMJ | 06/05/2020 | 10.1136/bmj.m1203 | 32376654 |
| PGP000125 | 1 | 1 | Marston NA | Clinical Application of a Novel Genetic Risk Score for Ischemic Stroke in Patients with Cardiometabolic Disease. | Circulation | 13/11/2020 | 10.1161/circulationaha.120.051927 | 33185476 |
| PGP000127 | 1 | 1 | Trinder M | Clinical Utility of Lipoprotein(a) and LPA Genetic Risk Score in Risk Prediction of Incident Atherosclerotic Cardiovascular Disease. | JAMA Cardiol | 06/10/2020 | 10.1001/jamacardio.2020.5398 | 33021622 |
| PGP000123 | 1 | 1 | Kim J | Genetic and Circulating Biomarker Data Improve Risk Prediction for Pancreatic Cancer in the General Population. | Cancer Epidemiol Biomarkers Prev | 22/04/2020 | 10.1158/1055-9965.epi-19-1389 | 32321713 |
| PGP000135 | 7 | 8 | Jia G | Evaluating the Utility of Polygenic Risk Scores in Identifying High-Risk Individuals for Eight Common Cancers. | JNCI Cancer Spectr | 12/03/2020 | 10.1093/jncics/pkaa021 | 32596635 |
| PGP000136 | 1 | 1 | Emdin CA | Association of genetic variation with cirrhosis: a multi-trait genome-wide association and gene-environment interaction study. | Gastroenterology | 10/12/2020 | 10.1053/j.gastro.2020.12.011 | 33310085 |
| PGP000143 | 0 | 1 | Fahed AC | Transethnic Transferability of a Genome-Wide Polygenic Score for Coronary Artery Disease. | Circ Genom Precis Med | 07/12/2020 | 10.1161/circgen.120.003092 | 33284643 |
| PGP000124 | 1 | 1 | Gorski M | Meta-analysis uncovers genome-wide significant variants for rapid kidney function decline. | Kidney Int | 30/10/2020 | 10.1016/j.kint.2020.09.030 | 33137338 |
| PGP000129 | 0 | 1 | Mosley JD | Predictive Accuracy of a Polygenic Risk Score Compared With a Clinical Risk Score for Incident Coronary Heart Disease. | JAMA | 01/02/2020 | 10.1001/jama.2019.21782 | 32068817 |
| PGP000134 | 1 | 1 | Lanfear DE | Polygenic Score for β-Blocker Survival Benefit in European Ancestry Patients With Reduced Ejection Fraction Heart Failure. | Circ Heart Fail | 04/10/2020 | 10.1161/circheartfailure.119.007012 | 33012170 |
| PGP000277 | 1 | 1 | Dareng EO | Polygenic risk modeling for prediction of epithelial ovarian cancer risk. | Eur J Hum Genet | 14/01/2022 | 10.1038/s41431-021-00987-7 | 35027648 |
| PGP000133 | 0 | 1 | Naito T | Prevalence and Effect of Genetic Risk of Thromboembolic Disease in Inflammatory Bowel Disease. | Gastroenterology | 21/10/2020 | 10.1053/j.gastro.2020.10.019 | 33098885 |
| PGP000130 | 1 | 1 | Sipeky C | Prostate cancer risk prediction using a polygenic risk score. | Sci Rep | 13/10/2020 | 10.1038/s41598-020-74172-z | 33051487 |
| PGP000128 | 46 | 46 | Sinnott-Armstrong N | Genetics of 35 blood and urine biomarkers in the UK Biobank. | Nat Genet | 18/01/2021 | 10.1038/s41588-020-00757-z | 33462484 |
| PGP000140 | 0 | 2 | Brandkvist M | Separating the genetics of childhood and adult obesity: a validation study of genetic scores for body mass index in adolescence and adulthood in the HUNT Study. | Hum Mol Genet | 04/12/2020 | 10.1093/hmg/ddaa256 | 33276378 |
| PGP000207 | 1 | 1 | van der Lee SJ | The effect of APOE and other common genetic variants on the onset of Alzheimer's disease and dementia: a community-based cohort study. | Lancet Neurol | 16/03/2018 | 10.1016/s1474-4422(18)30053-x | 29555425 |
| PGP000141 | 0 | 1 | Brandkvist M | Genetic associations with temporal shifts in obesity and severe obesity during the obesity epidemic in Norway: A longitudinal population-based cohort (the HUNT Study). | PLoS Med | 14/12/2020 | 10.1371/journal.pmed.1003452 | 33315864 |
| PGP000142 | 1 | 1 | Archambault AN | Cumulative Burden of Colorectal Cancer-Associated Genetic Variants Is More Strongly Associated With Early-Onset vs Late-Onset Cancer. | Gastroenterology | 19/12/2019 | 10.1053/j.gastro.2019.12.012 | 31866242 |
| PGP000138 | 3 | 3 | Fontanillas P | Disease risk scores for skin cancers. | Nat Commun | 08/01/2021 | 10.1038/s41467-020-20246-5 | 33420020 |
| PGP000164 | 3 | 3 | Khan Z | Genetic variation associated with thyroid autoimmunity shapes the systemic immune response to PD-1 checkpoint blockade. | Nat Commun | 07/06/2021 | 10.1038/s41467-021-23661-4 | 34099659 |
| PGP000145 | 1 | 1 | Roberts GHL | Family Clustering of Autoimmune Vitiligo Results Principally from Polygenic Inheritance of Common Risk Alleles. | Am J Hum Genet | 18/07/2019 | 10.1016/j.ajhg.2019.06.013 | 31327509 |
| PGP000144 | 3 | 3 | Tadros R | Predicting cardiac electrical response to sodium-channel blockade and Brugada syndrome using polygenic risk scores. | Eur Heart J | 01/10/2019 | 10.1093/eurheartj/ehz435 | 31504448 |
| PGP000146 | 1 | 1 | Harper AR | Common genetic variants and modifiable risk factors underpin hypertrophic cardiomyopathy susceptibility and expressivity. | Nat Genet | 25/01/2021 | 10.1038/s41588-020-00764-0 | 33495597 |
| PGP000208 | 0 | 1 | Riaz M | Effect of APOE and a polygenic risk score on incident dementia and cognitive decline in a healthy older population. | Aging Cell | 26/05/2021 | 10.1111/acel.13384 | 34041846 |
| PGP000168 | 0 | 1 | Plym A | Evaluation of a Multiethnic Polygenic Risk Score Model for Prostate Cancer. | J Natl Cancer Inst | 01/04/2021 | 10.1093/jnci/djab058 | 33792693 |
| PGP000167 | 0 | 3 | Maguire S | Common Susceptibility Loci for Male Breast Cancer. | J Natl Cancer Inst | 01/04/2021 | 10.1093/jnci/djaa101 | 32785646 |
| PGP000197 | 1 | 1 | Potjer TP | Association between a 46-SNP Polygenic Risk Score and melanoma risk in Dutch patients with familial melanoma. | J Med Genet | 29/09/2020 | 10.1136/jmedgenet-2020-107251 | 32994281 |
| PGP000139 | 1 | 2 | Karunamuni RA | African-specific improvement of a polygenic hazard score for age at diagnosis of prostate cancer. | Int J Cancer | 24/09/2020 | 10.1002/ijc.33282 | 32930425 |
| PGP000162 | 2 | 2 | Ouyang H | Association between genetic risk scores and risk of narcolepsy: a case-control study. | Ann Transl Med | 01/02/2020 | 10.21037/atm.2019.12.95 | 32175396 |
| PGP000148 | 1 | 1 | Hung RJ | Assessing Lung Cancer Absolute Risk Trajectory Based on a Polygenic Risk Model. | Cancer Res | 20/01/2021 | 10.1158/0008-5472.can-20-1237 | 33472890 |
| PGP000147 | 0 | 11 | Thareja G | Whole genome sequencing in the Middle Eastern Qatari population identifies genetic associations with 45 clinically relevant traits. | Nat Commun | 23/02/2021 | 10.1038/s41467-021-21381-3 | 33623009 |
| PGP000149 | 1 | 1 | Huynh-Le MP | Polygenic hazard score is associated with prostate cancer in multi-ethnic populations. | Nat Commun | 23/02/2021 | 10.1038/s41467-021-21287-0 | 33623038 |
| PGP000169 | 1 | 1 | Cole BS | The Role of Genetic Ancestry as a Risk Factor for Primary Open-angle Glaucoma in African Americans. | Invest Ophthalmol Vis Sci | 01/02/2021 | 10.1167/iovs.62.2.28 | 33605984 |
| PGP000185 | 1 | 1 | Adel Fahmideh M | A Weighted Genetic Risk Score of Adult Glioma Susceptibility Loci Associated with Pediatric Brain Tumor Risk. | Sci Rep | 02/12/2019 | 10.1038/s41598-019-54701-1 | 31792337 |
| PGP000186 | 16 | 32 | Kachuri L | Pan-cancer analysis demonstrates that integrating polygenic risk scores with modifiable risk factors improves risk prediction. | Nat Commun | 27/11/2020 | 10.1038/s41467-020-19600-4 | 33247094 |
| PGP000188 | 0 | 1 | Tangtanatakul P | Meta-analysis of genome-wide association study identifies FBN2 as a novel locus associated with systemic lupus erythematosus in Thai population. | Arthritis Res Ther | 08/08/2020 | 10.1186/s13075-020-02276-y | 32771030 |
| PGP000151 | 3 | 3 | Cust AE | Assessing the Incremental Contribution of Common Genomic Variants to Melanoma Risk Prediction in Two Population-Based Studies. | J Invest Dermatol | 08/06/2018 | 10.1016/j.jid.2018.05.023 | 29890168 |
| PGP000192 | 1 | 1 | Kawai VK | Pleiotropy of systemic lupus erythematosus risk alleles and cardiometabolic disorders: A phenome-wide association study and inverse-variance weighted meta-analysis. | Lupus | 12/05/2021 | 10.1177/09612033211014952 | 33977795 |
| PGP000218 | 0 | 1 | He Y | Comparisons of Polyexposure, Polygenic, and Clinical Risk Scores in Risk Prediction of Type 2 Diabetes. | Diabetes Care | 09/02/2021 | 10.2337/dc20-2049 | 33563654 |
| PGP000154 | 0 | 1 | Lu T | Improved prediction of fracture risk leveraging a genome-wide polygenic risk score. | Genome Med | 03/02/2021 | 10.1186/s13073-021-00838-6 | 33536041 |
| PGP000155 | 1 | 1 | Bobbili DR | Excess of singleton loss-of-function variants in Parkinson's disease contributes to genetic risk. | J Med Genet | 13/02/2020 | 10.1136/jmedgenet-2019-106316 | 32054687 |
| PGP000156 | 1 | 1 | Du Z | A genome-wide association study of prostate cancer in Latinos. | Int J Cancer | 03/07/2019 | 10.1002/ijc.32525 | 31226226 |
| PGP000157 | 1 | 1 | Dron JS | Genetic Predictor to Identify Individuals With High Lipoprotein(a) Concentrations. | Circ Genom Precis Med | 01/02/2021 | 10.1161/circgen.120.003182 | 33522245 |
| PGP000152 | 4 | 6 | Gola D | Population Bias in Polygenic Risk Prediction Models for Coronary Artery Disease. | Circ Genom Precis Med | 10/11/2020 | 10.1161/circgen.120.002932 | 33170024 |
| PGP000153 | 0 | 1 | Manousaki D | A Polygenic Risk Score as a Risk Factor for Medication-Associated Fractures. | J Bone Miner Res | 20/07/2020 | 10.1002/jbmr.4104 | 32511779 |
| PGP000150 | 1 | 2 | Karunamuni RA | Additional SNPs improve risk stratification of a polygenic hazard score for prostate cancer. | Prostate Cancer Prostatic Dis | 08/01/2021 | 10.1038/s41391-020-00311-2 | 33420416 |
| PGP000191 | 1 | 1 | He CY | Performance of common genetic variants in risk prediction for colorectal cancer in Chinese: A two-stage and multicenter study. | Genomics | 02/02/2021 | 10.1016/j.ygeno.2021.01.025 | 33545268 |
| PGP000161 | 1 | 1 | Cho SK | Polygenic analysis of the effect of common and low-frequency genetic variants on serum uric acid levels in Korean individuals. | Sci Rep | 08/06/2020 | 10.1038/s41598-020-66064-z | 32514006 |
| PGP000278 | 1 | 1 | Dashti HS | Interaction of obesity polygenic score with lifestyle risk factors in an electronic health record biobank. | BMC Med | 12/01/2022 | 10.1186/s12916-021-02198-9 | 35016652 |
| PGP000166 | 0 | 1 | Marston NA | Genetic Risk Score to Identify Risk of Venous Thromboembolism in Patients With Cardiometabolic Disease. | Circ Genom Precis Med | 12/01/2021 | 10.1161/circgen.120.003006 | 33434447 |
| PGP000159 | 1 | 1 | Klarin D | Genetic Architecture of Abdominal Aortic Aneurysm in the Million Veteran Program. | Circulation | 28/09/2020 | 10.1161/circulationaha.120.047544 | 32981348 |
| PGP000160 | 1 | 1 | Wang YF | Identification of 38 novel loci for systemic lupus erythematosus and genetic heterogeneity between ancestral groups. | Nat Commun | 03/02/2021 | 10.1038/s41467-021-21049-y | 33536424 |
| PGP000170 | 1 | 0 | Huyghe JR | Discovery of common and rare genetic risk variants for colorectal cancer. | Nat Genet | 03/12/2018 | 10.1038/s41588-018-0286-6 | 30510241 |
| PGP000209 | 0 | 1 | Neumann JT | Predictive Performance of a Polygenic Risk Score for Incident Ischemic Stroke in a Healthy Older Population. | Stroke | 27/05/2021 | 10.1161/strokeaha.120.033670 | 34039031 |
| PGP000194 | 1 | 1 | Barnes CLK | Contribution of common risk variants to multiple sclerosis in Orkney and Shetland. | Eur J Hum Genet | 04/06/2021 | 10.1038/s41431-021-00914-w | 34088990 |
| PGP000203 | 1 | 1 | Forrest IS | Genome-wide polygenic risk score for retinopathy of type 2 diabetes. | Hum Mol Genet | 01/05/2021 | 10.1093/hmg/ddab067 | 33704450 |
| PGP000219 | 0 | 1 | Huynh-Le MP | Common genetic and clinical risk factors: association with fatal prostate cancer in the Cohort of Swedish Men. | Prostate Cancer Prostatic Dis | 15/03/2021 | 10.1038/s41391-021-00341-4 | 33723363 |
| PGP000215 | 1 | 2 | Bianco C | Non-invasive stratification of hepatocellular carcinoma risk in non-alcoholic fatty liver using polygenic risk scores. | J Hepatol | 25/11/2020 | 10.1016/j.jhep.2020.11.024 | 33248170 |
| PGP000216 | 1 | 1 | Brentnall AR | A case-control evaluation of 143 single nucleotide polymorphisms for breast cancer risk stratification with classical factors and mammographic density. | Int J Cancer | 13/07/2019 | 10.1002/ijc.32541 | 31251818 |
| PGP000217 | 0 | 1 | De Vincentis A | A Polygenic Risk Score to Refine Risk Stratification and Prediction for Severe Liver Disease by Clinical Fibrosis Scores. | Clin Gastroenterol Hepatol | 04/06/2021 | 10.1016/j.cgh.2021.05.056 | 34091049 |
| PGP000165 | 2 | 2 | Cherny SS | Self-reported hearing loss questions provide a good measure for genetic studies: a polygenic risk score analysis from UK Biobank. | Eur J Hum Genet | 20/03/2020 | 10.1038/s41431-020-0603-2 | 32203203 |
| PGP000171 | 0 | 2 | Fahed AC | Polygenic background modifies penetrance of monogenic variants for tier 1 genomic conditions. | Nat Commun | 20/08/2020 | 10.1038/s41467-020-17374-3 | 32820175 |
| PGP000174 | 1 | 1 | Guffanti G | Depression genetic risk score is associated with anhedonia-related markers across units of analysis. | Transl Psychiatry | 19/09/2019 | 10.1038/s41398-019-0566-7 | 31537779 |
| PGP000198 | 0 | 2 | Borde J | Performance of breast cancer polygenic risk scores in 760 female CHEK2 germline mutation carriers. | J Natl Cancer Inst | 29/12/2020 | 10.1093/jnci/djaa203 | 33372680 |
| PGP000172 | 1 | 1 | Bakshi A | Genomic Risk Score for Melanoma in a Prospective Study of Older Individuals. | J Natl Cancer Inst | 10/04/2021 | 10.1093/jnci/djab076 | 33837773 |
| PGP000204 | 2 | 2 | Luo J | Immunotherapy-mediated thyroid dysfunction: genetic risk and impact on outcomes with PD-1 blockade in non-small cell lung cancer. | Clin Cancer Res | 08/07/2021 | 10.1158/1078-0432.ccr-21-0921 | 34244291 |
| PGP000220 | 1 | 1 | Kleinstern G | Association of polygenic risk score with the risk of chronic lymphocytic leukemia and monoclonal B-cell lymphocytosis. | Blood | 19/04/2018 | 10.1182/blood-2017-11-814608 | 29674426 |
| PGP000221 | 1 | 2 | Leal LG | A polygenic biomarker to identify patients with severe hypercholesterolemia of polygenic origin. | Mol Genet Genomic Med | 19/04/2020 | 10.1002/mgg3.1248 | 32307928 |
| PGP000176 | 1 | 1 | Sordillo JE | Pharmacogenetic Polygenic Risk Score for Bronchodilator Response in Children and Adolescents with Asthma: Proof-of-Concept. | J Pers Med | 20/04/2021 | 10.3390/jpm11040319 | 33923870 |
| PGP000177 | 1 | 1 | de Toro-Martín J | The Challenge of Stratifying Obesity: Attempts in the Quebec Family Study. | Front Genet | 10/10/2019 | 10.3389/fgene.2019.00994 | 31649740 |
| PGP000195 | 1 | 0 | Ferreira MA | Shared genetic origin of asthma, hay fever and eczema elucidates allergic disease biology. | Nat Genet | 30/10/2017 | 10.1038/ng.3985 | 29083406 |
| PGP000196 | 2 | 2 | Najar J | Polygenic risk scores for Alzheimer's disease are related to dementia risk in APOE ɛ4 negatives. | Alzheimers Dement (Amst) | 22/01/2021 | 10.1002/dad2.12142 | 33532541 |
| PGP000199 | 0 | 1 | Ferreira MAR | Age-of-onset information helps identify 76 genetic variants associated with allergic disease. | PLoS Genet | 30/06/2020 | 10.1371/journal.pgen.1008725 | 32603359 |
| PGP000200 | 1 | 1 | Talmud PJ | Use of low-density lipoprotein cholesterol gene score to distinguish patients with polygenic and monogenic familial hypercholesterolaemia: a case-control study. | Lancet | 22/02/2013 | 10.1016/s0140-6736(12)62127-8 | 23433573 |
| PGP000212 | 2 | 2 | Dongiovanni P | Causal relationship of hepatic fat with liver damage and insulin resistance in nonalcoholic fatty liver. | J Intern Med | 27/12/2017 | 10.1111/joim.12719 | 29280273 |
| PGP000181 | 1 | 1 | Liu G | Genome-wide survival study identifies a novel synaptic locus and polygenic score for cognitive progression in Parkinson's disease. | Nat Genet | 06/05/2021 | 10.1038/s41588-021-00847-6 | 33958783 |
| PGP000187 | 1 | 1 | Severance LM | Using a genetic risk score to calculate the optimal age for an individual to undergo coronary artery calcium screening. | J Cardiovasc Comput Tomogr | 09/05/2019 | 10.1016/j.jcct.2019.05.005 | 31104941 |
| PGP000182 | 1 | 2 | Tadros R | Shared genetic pathways contribute to risk of hypertrophic and dilated cardiomyopathies with opposite directions of effect. | Nat Genet | 25/01/2021 | 10.1038/s41588-020-00762-2 | 33495596 |
| PGP000210 | 8 | 8 | Zubair N | Genetic Predisposition Impacts Clinical Changes in a Lifestyle Coaching Program. | Sci Rep | 02/05/2019 | 10.1038/s41598-019-43058-0 | 31048771 |
| PGP000173 | 0 | 2 | Darst BF | Combined Effect of a Polygenic Risk Score and Rare Genetic Variants on Prostate Cancer Risk. | Eur Urol | 01/05/2021 | 10.1016/j.eururo.2021.04.013 | 33941403 |
| PGP000213 | 1 | 1 | Arabkhazaeli A | The association between a genetic risk score for allergy and the risk of developing allergies in childhood-Results of the WHISTLER cohort. | Pediatr Allergy Immunol | 22/11/2017 | 10.1111/pai.12824 | 29047167 |
| PGP000214 | 4 | 5 | Aksit MA | Genetic Modifiers of Cystic Fibrosis-Related Diabetes Have Extensive Overlap With Type 2 Diabetes and Related Traits. | J Clin Endocrinol Metab | 01/05/2020 | 10.1210/clinem/dgz102 | 31697830 |
| PGP000272 | 0 | 1 | McCormick N | Impact of adiposity on risk of female gout among those genetically predisposed: sex-specific prospective cohort study findings over >32 years. | Ann Rheum Dis | 02/12/2021 | 10.1136/annrheumdis-2021-221635 | 34857519 |
| PGP000227 | 1 | 1 | Xu J | Association of prostate cancer polygenic risk score with number and laterality of tumor cores in active surveillance patients. | Prostate | 06/05/2021 | 10.1002/pros.24140 | 33956350 |
| PGP000178 | 2 | 2 | Chen L | Genome-wide assessment of genetic risk for systemic lupus erythematosus and disease severity. | Hum Mol Genet | 01/06/2020 | 10.1093/hmg/ddaa030 | 32077931 |
| PGP000179 | 3 | 6 | Du Z | Evaluating Polygenic Risk Scores for Breast Cancer in Women of African Ancestry. | J Natl Cancer Inst | 26/03/2021 | 10.1093/jnci/djab050 | 33769540 |
| PGP000180 | 1 | 1 | Innes H | Genome-Wide Association Study for Alcohol-Related Cirrhosis Identifies Risk Loci in MARC1 and HNRNPUL1. | Gastroenterology | 16/06/2020 | 10.1053/j.gastro.2020.06.014 | 32561361 |
| PGP000183 | 1 | 1 | Zhou X | Genetic and polygenic risk score analysis for Alzheimer's disease in the Chinese population. | Alzheimers Dement (Amst) | 05/08/2020 | 10.1002/dad2.12074 | 32775599 |
| PGP000184 | 1 | 1 | Clark H | Differential associations of allergic disease genetic variants with developmental profiles of eczema, wheeze and rhinitis. | Clin Exp Allergy | 15/10/2019 | 10.1111/cea.13485 | 31441980 |
| PGP000175 | 1 | 1 | Lahrouchi N | Transethnic Genome-Wide Association Study Provides Insights in the Genetic Architecture and Heritability of Long QT Syndrome. | Circulation | 20/05/2020 | 10.1161/circulationaha.120.045956 | 32429735 |
| PGP000202 | 1 | 2 | Bauer A | Comparison of genetic risk prediction models to improve prediction of coronary heart disease in two large cohorts of the MONICA/KORA study. | Genet Epidemiol | 03/06/2021 | 10.1002/gepi.22389 | 34082474 |
| PGP000201 | 3 | 3 | Pazoki R | Genetic analysis in European ancestry individuals identifies 517 loci associated with liver enzymes. | Nat Commun | 10/05/2021 | 10.1038/s41467-021-22338-2 | 33972514 |
| PGP000205 | 0 | 1 | Rimbert A | Phenotypic Differences Between Polygenic and Monogenic Hypobetalipoproteinemia. | Arterioscler Thromb Vasc Biol | 19/11/2020 | 10.1161/atvbaha.120.315491 | 33207932 |
| PGP000206 | 1 | 1 | Teumer A | Genome-wide association meta-analyses and fine-mapping elucidate pathways influencing albuminuria. | Nat Commun | 11/09/2019 | 10.1038/s41467-019-11576-0 | 31511532 |
| PGP000228 | 1 | 1 | Revez JA | Genome-wide association study identifies 143 loci associated with 25 hydroxyvitamin D concentration. | Nat Commun | 02/04/2020 | 10.1038/s41467-020-15421-7 | 32242144 |
| PGP000234 | 0 | 1 | Kleinstern G | Polygenic risk score and risk of monoclonal B-cell lymphocytosis in caucasians and risk of chronic lymphocytic leukemia (CLL) in African Americans. | Leukemia | 20/07/2021 | 10.1038/s41375-021-01344-9 | 34285341 |
| PGP000223 | 1 | 1 | Lotta LA | Integrative genomic analysis implicates limited peripheral adipose storage capacity in the pathogenesis of human insulin resistance. | Nat Genet | 14/11/2016 | 10.1038/ng.3714 | 27841877 |
| PGP000224 | 1 | 1 | Oh JJ | Evaluation of Polygenic Risk Scores for Prediction of Prostate Cancer in Korean Men. | Front Oncol | 22/10/2020 | 10.3389/fonc.2020.583625 | 33194723 |
| PGP000230 | 12 | 12 | Graham SE | The power of genetic diversity in genome-wide association studies of lipids. | Nature | 09/12/2021 | https://doi.org/10.1038/s41586-021-04064-3 | 34887591 |
| PGP000226 | 1 | 1 | Xie J | Relationships of sleep traits with lung cancer risk: a prospective cohort study in UK Biobank. | Sleep | 05/04/2021 | 10.1093/sleep/zsab089 | 33823024 |
| PGP000222 | 1 | 2 | Leonenko G | Polygenic risk and hazard scores for Alzheimer's disease prediction. | Ann Clin Transl Neurol | 18/02/2019 | 10.1002/acn3.716 | 30911569 |
| PGP000231 | 1 | 1 | de Rojas I | Common variants in Alzheimer's disease and risk stratification by polygenic risk scores. | Nat Commun | 07/06/2021 | 10.1038/s41467-021-22491-8 | 34099642 |
| PGP000233 | 2 | 2 | Kauko A | Sex Differences in Genetic Risk for Hypertension. | Hypertension | 15/08/2021 | 10.1161/hypertensionaha.121.17796 | 34397277 |
| PGP000229 | 3 | 3 | Yu Z | Polygenic Risk Scores for Kidney Function and Their Associations with Circulating Proteome, and Incident Kidney Diseases. | J Am Soc Nephrol | 21/09/2021 | 10.1681/asn.2020111599 | 34548389 |
| PGP000239 | 1 | 1 | O'Sullivan JW | Combining Clinical and Polygenic Risk Improves Stroke Prediction Among Individuals With Atrial Fibrillation. | Circ Genom Precis Med | 15/06/2021 | 10.1161/circgen.120.003168 | 34029116 |
| PGP000241 | 1 | 1 | Wang M | A genome-wide association and polygenic risk score study on abnormal electrocardiogram in a Chinese population. | Sci Rep | 25/02/2021 | 10.1038/s41598-021-84135-7 | 33633301 |
| PGP000225 | 1 | 1 | Qassim A | An Intraocular Pressure Polygenic Risk Score Stratifies Multiple Primary Open-Angle Glaucoma Parameters Including Treatment Intensity. | Ophthalmology | 07/01/2020 | 10.1016/j.ophtha.2019.12.025 | 32081492 |
| PGP000232 | 1 | 1 | Feitosa MF | Heterogeneity of the Predictive Polygenic Risk Scores for Coronary Heart Disease Age-at-Onset in Three Different Coronary Heart Disease Family-Based Ascertainments. | Circ Genom Precis Med | 12/04/2021 | 10.1161/circgen.120.003201 | 33844929 |
| PGP000273 | 1 | 1 | Haas ME | Machine learning enables new insights into genetic contributions to liver fat accumulation. | Cell Genom | 01/12/2021 | 10.1016/j.xgen.2021.100066 | 34957434 |
| PGP000254 | 1 | 1 | Chairta PP | Prediction of Parkinson's Disease Risk Based on Genetic Profile and Established Risk Factors. | Genes (Basel) | 20/08/2021 | 10.3390/genes12081278 | 34440451 |
| PGP000235 | 2 | 2 | Nalls MA | Identification of novel risk loci, causal insights, and heritable risk for Parkinson's disease: a meta-analysis of genome-wide association studies. | Lancet Neurol | 01/12/2019 | 10.1016/s1474-4422(19)30320-5 | 31701892 |
| PGP000236 | 2 | 2 | Ntalla I | Multi-ancestry GWAS of the electrocardiographic PR interval identifies 202 loci underlying cardiac conduction. | Nat Commun | 21/05/2020 | 10.1038/s41467-020-15706-x | 32439900 |
| PGP000237 | 1 | 1 | Tesi N | Polygenic Risk Score of Longevity Predicts Longer Survival Across an Age Continuum. | J Gerontol A Biol Sci Med Sci | 01/04/2021 | 10.1093/gerona/glaa289 | 33216869 |
| PGP000238 | 4 | 4 | Campos AI | Understanding genetic risk factors for common side effects of antidepressant medications | medRxivPre | 16/07/2021 | 10.1101/2021.07.12.21260397 | — |
| PGP000240 | 2 | 2 | Vaura F | Polygenic Risk Scores Predict Hypertension Onset and Cardiovascular Risk. | Hypertension | 22/02/2021 | 10.1161/hypertensionaha.120.16471 | 33611940 |
| PGP000193 | 5 | 5 | Polfus LM | Genetic discovery and risk characterization in type 2 diabetes across diverse populations. | HGG Adv | 09/03/2021 | 10.1016/j.xhgg.2021.100029 | 34604815 |
| PGP000243 | 1 | 1 | Borisevich D | Non-linear interaction between physical activity and polygenic risk score of body mass index in Danish and Russian populations. | PLoS One | 18/10/2021 | 10.1371/journal.pone.0258748 | 34662357 |
| PGP000245 | 0 | 4 | Barnes DR | Breast and Prostate Cancer Risks for Male BRCA1 and BRCA2 Pathogenic Variant Carriers Using Polygenic Risk Scores. | J Natl Cancer Inst | 28/07/2021 | 10.1093/jnci/djab147 | 34320204 |
| PGP000246 | 3 | 3 | Chen J | The trans-ancestral genomic architecture of glycemic traits. | Nat Genet | 31/05/2021 | 10.1038/s41588-021-00852-9 | 34059833 |
| PGP000211 | 33 | 34 | Aly DM | Genome-wide association analyses highlight etiological differences underlying newly defined subtypes of diabetes | Nat Genet | 04/11/2021 | 10.1038/s41588-021-00948-2 | 34737425 |
| PGP000051 | 26 | 26 | Xu Y | Machine learning optimized polygenic scores for blood cell traits identify sex-specific trajectories and genetic correlations with disease | Cell Genom | 12/01/2022 | 10.1016/j.xgen.2021.100086 | 35072137 |
| PGP000255 | 1 | 1 | Ebenau JL | Risk of dementia in <i>APOE</i> ε4 carriers is mitigated by a polygenic risk score. | Alzheimers Dement (Amst) | 14/09/2021 | 10.1002/dad2.12229 | 34541285 |
| PGP000247 | 0 | 1 | Lacaze P | Genomic Risk Prediction for Breast Cancer in Older Women. | Cancers (Basel) | 14/07/2021 | 10.3390/cancers13143533 | 34298747 |
| PGP000248 | 0 | 2 | Liou L | Genomic risk prediction of coronary artery disease in women with breast cancer: a prospective cohort study. | Breast Cancer Res | 30/09/2021 | 10.1186/s13058-021-01465-0 | 34593009 |
| PGP000249 | 0 | 4 | Liu C | Generalizability of Polygenic Risk Scores for Breast Cancer Among Women With European, African, and Latinx Ancestry. | JAMA Netw Open | 02/08/2021 | 10.1001/jamanetworkopen.2021.19084 | 34347061 |
| PGP000250 | 1 | 1 | Sia MW | Polygenic Risk Scores in a Prospective Parkinson's Disease Cohort. | Mov Disord | 17/08/2021 | 10.1002/mds.28761 | 34402545 |
| PGP000251 | 1 | 1 | Song N | Polygenic Risk Score Improves Risk Stratification and Prediction of Subsequent Thyroid Cancer after Childhood Cancer. | Cancer Epidemiol Biomarkers Prev | 31/08/2021 | 10.1158/1055-9965.epi-21-0448 | 34465587 |
| PGP000252 | 3 | 3 | Ye Y | Interactions Between Enhanced Polygenic Risk Scores and Lifestyle for Cardiovascular Disease, Diabetes, and Lipid Levels. | Circ Genom Precis Med | 12/01/2021 | 10.1161/circgen.120.003128 | 33433237 |
| PGP000137 | 3 | 4 | Ritchie SC | Integrative analysis of the plasma proteome and polygenic risk of cardiometabolic diseases | Nat Metab | 08/11/2021 | 10.1038/s42255-021-00478-5 | 34750571 |
| PGP000253 | 1 | 1 | Simard M | Polygenic risk score for atopic dermatitis in the Canadian population. | J Allergy Clin Immunol | 19/05/2020 | 10.1016/j.jaci.2020.04.057 | 32439431 |
| PGP000259 | 1 | 1 | Yiangou K | Combination of a 15-SNP Polygenic Risk Score and Classical Risk Factors for the Prediction of Breast Cancer Risk in Cypriot Women. | Cancers (Basel) | 11/09/2021 | 10.3390/cancers13184568 | 34572793 |
| PGP000258 | 1 | 1 | Whitfield JB | A genetic risk score and diabetes predict development of alcohol-related cirrhosis in drinkers. | J Hepatol | 13/10/2021 | 10.1016/j.jhep.2021.10.005 | 34656649 |
| PGP000276 | 1 | 1 | Lourida I | Association of Lifestyle and Genetic Risk With Incidence of Dementia. | JAMA | 01/08/2019 | 10.1001/jama.2019.9879 | 31302669 |
| PGP000256 | 1 | 1 | Gafni A | Ability of known colorectal cancer susceptibility SNPs to predict colorectal cancer risk: A cohort study within the UK Biobank. | PLoS One | 15/09/2021 | 10.1371/journal.pone.0251469 | 34525106 |
| PGP000257 | 0 | 1 | Wells QS | Polygenic Risk Score to Identify Subclinical Coronary Heart Disease Risk in Young Adults. | Circ Genom Precis Med | 31/08/2021 | 10.1161/circgen.121.003341 | 34463132 |
| PGP000265 | 1 | 1 | Bonfiglio F | GWAS of stool frequency provides insights into gastrointestinal motility and irritable bowel syndrome. | Cell Genom | 08/12/2021 | 10.1016/j.xgen.2021.100069 | 34957435 |
| PGP000263 | 430 | 430 | Privé F | Portability of 245 polygenic scores when derived from the UK Biobank and applied to 9 ancestry groups from the same cohort | Am J Hum Genet | 06/01/2022 | 10.1016/j.ajhg.2021.11.008 | 34995502 |
| PGP000266 | 2 | 2 | Chen LS | Use of polygenic risk scores of nicotine metabolism in predicting smoking behaviors. | Pharmacogenomics | 16/11/2018 | 10.2217/pgs-2018-0081 | 30442082 |
| PGP000267 | 1 | 1 | Kolin DA | Prediction of primary venous thromboembolism based on clinical and genetic factors within the U.K. Biobank. | Sci Rep | 01/11/2021 | 10.1038/s41598-021-00796-4 | 34725413 |
| PGP000264 | 2 | 2 | Moll M | Chronic obstructive pulmonary disease and related phenotypes: polygenic risk scores in population-based and case-control cohorts. | Lancet Respir Med | 01/07/2020 | 10.1016/s2213-2600(20)30101-6 | 32649918 |
| PGP000275 | 1 | 1 | Kothalawala DM | Integration of Genomic Risk Scores to Improve the Prediction of Childhood Asthma Diagnosis | J Pers Med | 08/01/2022 | 10.3390/jpm12010075 | 35055391 |
| PGP000274 | 3 | 3 | Steinberg J | Independent evaluation of melanoma polygenic risk scores in UK and Australian prospective cohorts. | Br J Dermatol | 18/12/2021 | 10.1111/bjd.20956 | 34921685 |
| PGP000279 | 1 | 1 | Archambault AN | Risk Stratification for Early-Onset Colorectal Cancer Using a Combination of Genetic and Environmental Risk Scores: An International Multi-Center Study. | J Natl Cancer Inst | 13/01/2022 | 10.1093/jnci/djac003 | 35026030 |
| PGP000269 | 1 | 1 | Khan A | Genome-wide polygenic score to predict chronic kidney disease across ancestries. | Nat Med | 16/06/2022 | 10.1038/s41591-022-01869-1 | 35710995 |
| PGP000280 | 2 | 2 | Kujala UM | Polygenic Risk Scores and Physical Activity. | Med Sci Sports Exerc | 01/07/2020 | 10.1249/mss.0000000000002290 | 32049886 |
| PGP000281 | 0 | 1 | Koch S | Validity and Prognostic Value of a Polygenic Risk Score for Parkinson's Disease. | Genes (Basel) | 23/11/2021 | 10.3390/genes12121859 | 34946808 |
| PGP000282 | 1 | 1 | Wu Q | An early prediction model for gestational diabetes mellitus based on genetic variants and clinical characteristics in China. | Diabetol Metab Syndr | 24/01/2022 | 10.1186/s13098-022-00788-y | 35073990 |
| PGP000283 | 2 | 2 | Evangelou E | Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits. | Nat Genet | 17/09/2018 | 10.1038/s41588-018-0205-x | 30224653 |
| PGP000284 | 0 | 2 | Tapela NM | Are polygenic risk scores for systolic blood pressure and LDL-cholesterol associated with treatment effectiveness, and clinical outcomes among those on treatment? | Eur J Prev Cardiol | 02/12/2021 | 10.1093/eurjpc/zwab192 | 34864974 |
| PGP000261 | 2 | 2 | Tamlander M | Integration of questionnaire-based risk factors improves polygenic risk scores for human coronary heart disease and type 2 diabetes. | Commun Biol | 23/02/2022 | 10.1038/s42003-021-02996-0 | 35197564 |
| PGP000285 | 1 | 1 | Lu X | Development and Validation of a Polygenic Risk Score for Stroke in the Chinese Population. | Neurology | 24/05/2021 | 10.1212/wnl.0000000000012263 | 34031205 |
| PGP000286 | 1 | 1 | Honda S | Polygenic risk scores are associated with radiographic progression in patients with rheumatoid arthritis. | Arthritis Rheumatol | 20/01/2022 | 10.1002/art.42051 | 35048562 |
| PGP000291 | 1 | 1 | Piekos JA | Uterine fibroid polygenic risk score (PRS) associates and predicts risk for uterine fibroid. | Hum Genet | 28/02/2022 | 10.1007/s00439-022-02442-z | 35226188 |
| PGP000287 | 1 | 1 | Testori A | Genetic analysis in African American children supports ancestry specific neuroblastoma susceptibility. | Cancer Epidemiol Biomarkers Prev | 07/02/2022 | 10.1158/1055-9965.epi-21-0782 | 35131881 |
| PGP000289 | 1 | 1 | Lu X | A polygenic risk score improves risk stratification of coronary artery disease: a large-scale prospective Chinese cohort study. | Eur Heart J | 23/02/2022 | 10.1093/eurheartj/ehac093 | 35195259 |
| PGP000290 | 0 | 1 | Mordi IR | Prediction of Major Adverse Cardiovascular Events From Retinal, Clinical, and Genomic Data in Individuals With Type 2 Diabetes: A Population Cohort Study. | Diabetes Care | 01/03/2022 | 10.2337/dc21-1124 | 35043139 |
| PGP000288 | 0 | 1 | Garcia-Etxebarria K | Local genetic variation of inflammatory bowel disease in Basque population and its effect in risk prediction. | Sci Rep | 01/03/2022 | 10.1038/s41598-022-07401-2 | 35232999 |
| PGP000293 | 1 | 1 | Sharma S | Predicting Pancreatic Cancer in the UK Biobank Cohort Using Polygenic Risk Scores and Diabetes Mellitus. | Gastroenterology | 21/01/2022 | 10.1053/j.gastro.2022.01.016 | 35065983 |
| PGP000323 | 1 | 1 | Shen M | Associations of combined lifestyle and genetic risks with incident psoriasis: A prospective cohort study among UK Biobank participants of European ancestry. | J Am Acad Dermatol | 12/04/2022 | 10.1016/j.jaad.2022.04.006 | 35427684 |
| PGP000324 | 1 | 1 | Yang Y | Incorporating Polygenic Risk Scores and Nongenetic Risk Factors for Breast Cancer Risk Prediction Among Asian Women. | JAMA Netw Open | 01/03/2022 | 10.1001/jamanetworkopen.2021.49030 | 35311964 |
| PGP000300 | 1 | 1 | Zhang P | Association of smoking and polygenic risk with the incidence of lung cancer: a prospective cohort study. | Br J Cancer | 22/02/2022 | 10.1038/s41416-022-01736-3 | 35194190 |
| PGP000270 | 2 | 2 | Breeyear JH | Blood Pressure Polygenic Scores Are Associated With Apparent Treatment-Resistant Hypertension. | Circ Genom Precis Med | 06/05/2022 | 10.1161/circgen.121.003554 | 35522175 |
| PGP000325 | 1 | 1 | Tsai CW | Prognostic significance of circulating insulin growth-like factor 1 and insulin growth-like factor binding protein 3 in renal cell carcinoma patients. | American Journal of Cancer Research | 15/02/2022 | — | 35261807 |
| PGP000292 | 0 | 3 | Saad M | Genetic predisposition to cancer across people of different ancestries in Qatar: a population-based, cohort study. | Lancet Oncol | 09/02/2022 | 10.1016/s1470-2045(21)00752-x | 35150601 |
| PGP000294 | 1 | 1 | Thomas M | Genome-wide Modeling of Polygenic Risk Score in Colorectal Cancer Risk. | Am J Hum Genet | 05/08/2020 | 10.1016/j.ajhg.2020.07.006 | 32758450 |
| PGP000295 | 1 | 1 | Yu Y | Polygenic risk impacts PDGFRA mutation penetrance in nonsyndromic cleft lip and palate. | Hum Mol Genet | 11/02/2022 | 10.1093/hmg/ddac037 | 35147171 |
| PGP000260 | 1 | 1 | Barc J | Genome-wide association analyses identify new Brugada syndrome risk loci and highlight a new mechanism of sodium channel regulation in disease susceptibility. | Nat Genet | 24/02/2022 | 10.1038/s41588-021-01007-6 | 35210625 |
| PGP000163 | 1 | 1 | Lu T | A polygenic risk score to predict future adult short stature amongst children. | J Clin Endocrinol Metab | 31/03/2021 | 10.1210/clinem/dgab215 | 33788949 |
| PGP000244 | 779 | 814 | Tanigawa Y | Significant sparse polygenic risk scores across 813 traits in UK Biobank. | PLoS Genet | 24/03/2022 | 10.1371/journal.pgen.1010105 | 35324888 |
| PGP000297 | 0 | 1 | Hurson AN | Prospective evaluation of a breast-cancer risk model integrating classical risk factors and polygenic risk in 15 cohorts from six countries. | Int J Epidemiol | 01/01/2022 | 10.1093/ije/dyab036 | 34999890 |
| PGP000305 | 1 | 1 | Siddiqui MK | Young-onset diabetes in Asian Indians is associated with lower measured and genetically determined beta cell function. | Diabetologia | 05/03/2022 | 10.1007/s00125-022-05671-z | 35247066 |
| PGP000306 | 0 | 1 | Thompson PL | Common genetic variants do not predict recurrent events in coronary heart disease patients. | BMC Cardiovasc Disord | 09/03/2022 | 10.1186/s12872-022-02520-0 | 35264114 |
| PGP000311 | 0 | 1 | Olmastroni E | Twelve Variants Polygenic Score for Low-Density Lipoprotein Cholesterol Distribution in a Large Cohort of Patients With Clinically Diagnosed Familial Hypercholesterolemia With or Without Causative Mutations. | J Am Heart Assoc | 24/03/2022 | 10.1161/jaha.121.023668 | 35322671 |
| PGP000329 | 1 | 1 | Zhang Y | Healthy lifestyle counteracts the risk effect of genetic factors on incident gout: a large population-based longitudinal study. | BMC Med | 29/04/2022 | 10.1186/s12916-022-02341-0 | 35484537 |
| PGP000271 | 5 | 5 | Mars N | Genome-wide risk prediction of common diseases across ancestries in one million people. | Cell Genom | 13/04/2022 | 10.1016/j.xgen.2022.100118 | 35591975 |
| PGP000337 | 1 | 1 | Mayerhofer E | Genetically predicted on-statin LDL response is associated with higher intracerebral haemorrhage risk. | Brain | 22/05/2022 | 10.1093/brain/awac186 | 35598204 |
| PGP000301 | 1 | 1 | Roselli C | Genome-wide association study reveals novel genetic loci: a new polygenic risk score for mitral valve prolapse. | Eur Heart J | 04/03/2022 | 10.1093/eurheartj/ehac049 | 35245370 |
| PGP000298 | 1 | 1 | Song SH | Prediction of clinically significant prostate cancer using polygenic risk models in Asians. | Investig Clin Urol | 01/01/2022 | 10.4111/icu.20210305 | 34983122 |
| PGP000308 | 0 | 1 | Schaid DJ | Polygenic risk for prostate cancer: Decreasing relative risk with age but little impact on absolute risk. | Am J Hum Genet | 23/03/2022 | 10.1016/j.ajhg.2022.03.008 | 35353984 |
| PGP000310 | 1 | 1 | Canzian F | A polygenic risk score for multiple myeloma risk prediction. | Eur J Hum Genet | 30/11/2021 | 10.1038/s41431-021-00986-8 | 34845334 |
| PGP000312 | 2 | 2 | Schnurr TM | Interactions of physical activity, muscular fitness, adiposity, and genetic risk for NAFLD. | Hepatol Commun | 15/03/2022 | 10.1002/hep4.1932 | 35293152 |
| PGP000326 | 1 | 1 | Maj C | Dissecting the Polygenic Basis of Primary Hypertension: Identification of Key Pathway-Specific Components. | Front Cardiovasc Med | 16/02/2022 | 10.3389/fcvm.2022.814502 | 35252394 |
| PGP000327 | 1 | 1 | Coassin S | Genome-Wide Characterization of a Highly Penetrant Form of Hyperlipoprotein(a)emia Associated With Genetically Elevated Cardiovascular Risk. | Circ Genom Precis Med | 08/02/2022 | 10.1161/circgen.121.003489 | 35133173 |
| PGP000302 | 2 | 2 | Horowitz JE | Genome-wide analysis provides genetic evidence that ACE2 influences COVID-19 risk and yields risk scores associated with severe disease. | Nat Genet | 03/03/2022 | 10.1038/s41588-021-01006-7 | 35241825 |
| PGP000303 | 2 | 2 | Groenland EH | Genetic variants associated with low-density lipoprotein cholesterol and systolic blood pressure and the risk of recurrent cardiovascular disease in patients with established vascular disease. | Atherosclerosis | 11/03/2022 | 10.1016/j.atherosclerosis.2022.03.006 | 35317921 |
| PGP000296 | 1 | 1 | Pirruccello JP | Deep learning enables genetic analysis of the human thoracic aorta. | Nat Genet | 26/11/2021 | 10.1038/s41588-021-00962-4 | 34837083 |
| PGP000299 | 1 | 1 | Zekavat SM | Photoreceptor Layer Thinning Is an Early Biomarker for Age-Related Macular Degeneration: Epidemiologic and Genetic Evidence from UK Biobank OCT Data. | Ophthalmology | 08/02/2022 | 10.1016/j.ophtha.2022.02.001 | 35149155 |
| PGP000304 | 1 | 1 | Nauffal V | Monogenic and Polygenic Contributions to QTc Prolongation in the Population. | Circulation | 07/04/2022 | 10.1161/circulationaha.121.057261 | 35389749 |
| PGP000307 | 2 | 2 | Forrest IS | Genetic and phenotypic profiling of supranormal ejection fraction reveals decreased survival and underdiagnosed heart failure. | Eur J Heart Fail | 12/03/2022 | 10.1002/ejhf.2482 | 35278270 |
| PGP000315 | 0 | 1 | Hämmerle M | A Family and a Genome-Wide Polygenic Risk Score Are Independently Associated With Stroke in a Population-Based Study. | Stroke | 07/04/2022 | 10.1161/strokeaha.121.036551 | 35387493 |
| PGP000319 | 0 | 1 | Guo F | Polygenic Risk Score for Defining Personalized Surveillance Intervals After Adenoma Detection and Removal at Colonoscopy. | Clin Gastroenterol Hepatol | 21/03/2022 | 10.1016/j.cgh.2022.03.013 | 35331942 |
| PGP000320 | 1 | 1 | He YQ | A polygenic risk score for nasopharyngeal carcinoma shows potential for risk stratification and personalized screening. | Nat Commun | 12/04/2022 | 10.1038/s41467-022-29570-4 | 35414057 |
| PGP000321 | 1 | 1 | He W | Association of Novel Loci With Keratoconus Susceptibility in a Multitrait Genome-Wide Association Study of the UK Biobank Database and Canadian Longitudinal Study on Aging. | JAMA Ophthalmol | 21/04/2022 | 10.1001/jamaophthalmol.2022.0891 | 35446358 |
| PGP000322 | 0 | 1 | Klein RJ | Prostate cancer polygenic risk score and prediction of lethal prostate cancer. | NPJ Precis Oncol | 08/04/2022 | 10.1038/s41698-022-00266-8 | 35396534 |
| PGP000316 | 1 | 1 | Zimmerman SC | Association of Genetic Variants Linked to Late-Onset Alzheimer Disease With Cognitive Test Performance by Midlife. | JAMA Netw Open | 01/04/2022 | 10.1001/jamanetworkopen.2022.5491 | 35377426 |
| PGP000317 | 0 | 2 | Parcha V | Association of Polygenic Risk Score With Blood Pressure and Adverse Cardiovascular Outcomes in Individuals With Type II Diabetes: Insights From the ACCORD Trial. | Hypertension | 04/04/2022 | 10.1161/hypertensionaha.122.18976 | 35369713 |
| PGP000318 | 1 | 1 | Gurung RL | Genetic risk score for plasma uric acid levels is associated with early rapid kidney function decline in type 2 diabetes. | J Clin Endocrinol Metab | 01/04/2022 | 10.1210/clinem/dgac192 | 35363857 |
| PGP000328 | 9 | 9 | Choi J | Evaluating polygenic risk scores in assessing risk of nine solid and hematologic cancers in European descendants. | Int J Cancer | 09/07/2020 | 10.1002/ijc.33176 | 32588423 |
| PGP000314 | 1 | 1 | Pujol-Gualdo N | Advancing our understanding of genetic risk factors and potential personalized strategies for pelvic organ prolapse. | Nat Commun | 23/06/2022 | 10.1038/s41467-022-31188-5 | 35739095 |
| PGP000313 | 4 | 4 | Kamiza AB | Transferability of genetic risk scores in African populations. | Nat Med | 02/06/2022 | 10.1038/s41591-022-01835-x | 35654908 |
| PGP000330 | 0 | 1 | Gratton J | LDL-C Concentrations and the 12-SNP LDL-C Score for Polygenic Hypercholesterolaemia in Self-Reported South Asian, Black and Caribbean Participants of the UK Biobank. | Front Genet | 31/03/2022 | 10.3389/fgene.2022.845498 | 35432461 |
| PGP000332 | 415 | 415 | Weissbrod O | Leveraging fine-mapping and multipopulation training data to improve cross-population polygenic risk scores. | Nat Genet | 07/04/2022 | 10.1038/s41588-022-01036-9 | 35393596 |
| PGP000268 | 1 | 1 | Tcheandjieu C | High heritability of ascending aortic diameter and trans-ancestry prediction of thoracic aortic disease. | Nat Genet | 30/05/2022 | 10.1038/s41588-022-01070-7 | 35637384 |
| PGP000338 | 0 | 2 | Oram RA | Utility of Diabetes Type-Specific Genetic Risk Scores for the Classification of Diabetes Type Among Multiethnic Youth. | Diabetes Care | 01/05/2022 | 10.2337/dc20-2872 | 35312757 |
| PGP000331 | 1 | 1 | Ge T | Development and validation of a trans-ancestry polygenic risk score for type 2 diabetes in diverse populations. | Genome Med | 29/06/2022 | 10.1186/s13073-022-01074-2 | 35765100 |
| PGP000334 | 1 | 1 | Shams H | Polygenic risk score association with multiple sclerosis susceptibility and phenotype in Europeans. | Brain | 07/03/2022 | 10.1093/brain/awac092 | 35253861 |
| PGP000335 | 1 | 1 | Namjou B | Multiancestral polygenic risk score for pediatric asthma. | J Allergy Clin Immunol | 18/05/2022 | 10.1016/j.jaci.2022.03.035 | 35595084 |
| PGP000336 | 2 | 2 | Sedaghati-Khayat B | Risk assessment for hip and knee osteoarthritis using polygenic risk scores. | Arthritis Rheumatol | 29/05/2022 | 10.1002/art.42246 | 35644035 |
| PGP000339 | 1 | 1 | Xicota L | Association of APOE-Independent Alzheimer Disease Polygenic Risk Score With Brain Amyloid Deposition in Asymptomatic Older Adults. | Neurology | 23/05/2022 | 10.1212/wnl.0000000000200544 | 35606148 |
| PGP000340 | 0 | 1 | Vacher M | Assessment of a polygenic hazard score for the onset of pre-clinical Alzheimer's disease. | BMC Genomics | 26/05/2022 | 10.1186/s12864-022-08617-2 | 35619096 |
| PGP000344 | 3 | 3 | Bafligil C | Development and evaluation of polygenic risk scores for prediction of endometrial cancer risk in European women. | Genet Med | 15/06/2022 | 10.1016/j.gim.2022.05.014 | 35704044 |
| PGP000355 | 0 | 2 | Borde J | Polygenic risk scores indicate extreme ages at onset of breast cancer in female BRCA1/2 pathogenic variant carriers. | BMC Cancer | 27/06/2022 | 10.1186/s12885-022-09780-1 | 35761208 |
| PGP000347 | 1 | 1 | Yuan C | The age-dependent association of risk factors with pancreatic cancer. | Ann Oncol | 06/04/2022 | 10.1016/j.annonc.2022.03.276 | 35398288 |
| PGP000348 | 0 | 1 | Hu X | Polygenic transcriptome risk scores for COPD and lung function improve cross-ethnic portability of prediction in the NHLBI TOPMed program. | Am J Hum Genet | 05/04/2022 | 10.1016/j.ajhg.2022.03.007 | 35385699 |
| PGP000341 | 1 | 1 | Vujkovic M | A multiancestry genome-wide association study of unexplained chronic ALT elevation as a proxy for nonalcoholic fatty liver disease with histological and radiological validation. | Nat Genet | 02/06/2022 | 10.1038/s41588-022-01078-z | 35654975 |
| PGP000359 | 1 | 1 | Liu Y | Genetic risk, metabolic syndrome, and gastrointestinal cancer risk: A prospective cohort study. | Cancer Med | 22/06/2022 | 10.1002/cam4.4923 | 35730595 |
| PGP000342 | 1 | 1 | Pezzilli S | Contribution of rare variants in monogenic diabetes-genes to early-onset type 2 diabetes. | Diabetes Metab | 26/04/2022 | 10.1016/j.diabet.2022.101353 | 35487478 |
| PGP000343 | 1 | 1 | Marques-Vidal P | Association between genetic risk of high SBP and hypertension control: the CoLaus|PsyColaus study. | J Hypertens | 10/06/2022 | 10.1097/hjh.0000000000003158 | 35703291 |
| PGP000345 | 1 | 1 | Lai D | Evaluating risk for alcohol use disorder: Polygenic risk scores and family history. | Alcohol Clin Exp Res | 10/03/2022 | 10.1111/acer.14772 | 35267208 |
| PGP000350 | 0 | 1 | Niedermaier T | Combined Performance of Fecal Immunochemical Tests and a Genetic Risk Score for Advanced Neoplasia Detection. | Cancer Prev Res (Phila) | 01/08/2022 | 10.1158/1940-6207.capr-21-0552 | 35679356 |
| PGP000351 | 0 | 3 | Li S | Genetic Aspects of Mammographic Density Measures Associated with Breast Cancer Risk. | Cancers (Basel) | 02/06/2022 | 10.3390/cancers14112767 | 35681745 |
| PGP000352 | 1 | 1 | Waksmunski AR | Glaucoma genetic risk scores in the Million Veteran Program. | Ophthalmology | 16/06/2022 | 10.1016/j.ophtha.2022.06.012 | 35718050 |
| PGP000353 | 0 | 1 | Sapkota Y | Contribution of Genome-Wide Polygenic Score to Risk of Coronary Artery Disease in Childhood Cancer Survivors. | JACC CardioOncol | 21/06/2022 | 10.1016/j.jaccao.2022.04.003 | 35818558 |
| PGP000354 | 3 | 3 | Ping J | Developing and validating polygenic risk scores for colorectal cancer risk prediction in East Asians. | Int J Cancer | 29/06/2022 | 10.1002/ijc.34194 | 35765848 |
| PGP000356 | 0 | 1 | Varma A | Early prediction of prostate cancer risk in younger men using polygenic risk scores and electronic health records. | Cancer Med | 25/06/2022 | 10.1002/cam4.4934 | 35751453 |
| PGP000346 | 1 | 1 | Lai D | Gene-based polygenic risk scores analysis of alcohol use disorder in African Americans. | Transl Psychiatry | 05/07/2022 | 10.1038/s41398-022-02029-2 | 35790736 |
| PGP000349 | 0 | 1 | Shi M | Association of Genome-Wide Polygenic Risk Score for Body Mass Index With Cardiometabolic Health From Childhood Through Midlife. | Circ Genom Precis Med | 08/06/2022 | 10.1161/circgen.121.003375 | 35675159 |
| PGP000262 | 18 | 18 | Wang Y | Global biobank analyses provide lessons for computing polygenic risk scores across diverse cohorts | medRxivPre | 21/11/2021 | 10.1101/2021.11.18.21266545 | — |
| PGP000358 | 1 | 1 | Lahey BB | Associations of polygenic risk for attention-deficit/hyperactivity disorder with general and specific dimensions of childhood psychological problems and facets of impulsivity. | J Psychiatr Res | 14/06/2022 | 10.1016/j.jpsychires.2022.06.019 | 35752070 |
| PGP000362 | 2 | 2 | Lacaze P | Genomic Risk Score for Advanced Osteoarthritis in Older Adults. | Arthritis Rheumatol | 23/07/2022 | 10.1002/art.42156 | 35506208 |
| PGP000363 | 1 | 2 | Sapkota Y | Genetic risk score enhances the risk prediction of severe obesity in adult survivors of childhood cancer. | Nat Med | 25/07/2022 | 10.1038/s41591-022-01902-3 | 35879615 |
| PGP000360 | 0 | 1 | Kukkle PL | Genome-Wide Polygenic Score Predicts Large Number of High Risk Individuals in Monogenic Undiagnosed Young Onset Parkinson's Disease Patients from India. | Adv Biol (Weinh) | 10/07/2022 | 10.1002/adbi.202101326 | 35810474 |
| PGP000361 | 1 | 1 | Chiou JS | Your height affects your health: genetic determinants and health-related outcomes in Taiwan. | BMC Med | 13/07/2022 | 10.1186/s12916-022-02450-w | 35831902 |
| PGP000371 | 3 | 3 | Ruan X | Application of European-specific polygenic risk scores for predicting prostate cancer risk in different ancestry populations. | Prostate | 22/08/2022 | 10.1002/pros.24431 | 35996327 |
| PGP000367 | 0 | 1 | Green HD | Applying a genetic risk score for prostate cancer to men with lower urinary tract symptoms in primary care to predict prostate cancer diagnosis: a cohort study in the UK Biobank. | Br J Cancer | 18/08/2022 | 10.1038/s41416-022-01918-z | 35978138 |
| PGP000373 | 0 | 3 | Kim MS | Testing the generalizability of ancestry-specific polygenic risk scores to predict prostate cancer in sub-Saharan Africa. | Genome Biol | 13/09/2022 | 10.1186/s13059-022-02766-z | 36100952 |
| PGP000372 | 0 | 1 | Clarke SL | Broad clinical manifestations of polygenic risk for coronary artery disease in the Women's Health Initiative. | Commun Med (Lond) | 25/08/2022 | 10.1038/s43856-022-00171-y | 36034645 |
| PGP000370 | 6 | 6 | Gui Y | Sex-specific genetic association between psychiatric disorders and cognition, behavior and brain imaging in children and adults. | Transl Psychiatry | 26/08/2022 | 10.1038/s41398-022-02041-6 | 36028495 |
| PGP000368 | 0 | 1 | Marston NA | A polygenic risk score predicts atrial fibrillation in cardiovascular disease. | Eur Heart J | 18/08/2022 | 10.1093/eurheartj/ehac460 | 35980763 |
| PGP000369 | 0 | 1 | Jaworek T | Contribution of Common Genetic Variants to Risk of Early Onset Ischemic Stroke | Neurology | 31/08/2022 | 10.1212/WNL.0000000000201006 | — |
| PGP000333 | 2 | 3 | Mishra A | Stroke genetics informs drug discovery and risk prediction across ancestries | Nature | 30/09/2022 | 10.1038/s41586-022-05165-3 | — |