Publications

PGS Publication/Study ID (PGP) PGS Developed PGS Evaluated First Author Title Journal Name Publication Date Digital object identifier (doi) PubMed ID (PMID)
PGP000410 20 20 Saunders GRB Genetic diversity fuels gene discovery for tobacco and alcohol use. Nature 07/12/2022 10.1038/s41586-022-05477-4 36477530
PGP000089 79 79 Folkersen L Genomic and drug target evaluation of 90 cardiovascular proteins in 30,931 individuals. Nat Metab 16/10/2020 10.1038/s42255-020-00287-2 33067605
PGP000137 3 4 Ritchie SC Integrative analysis of the plasma proteome and polygenic risk of cardiometabolic diseases Nat Metab 08/11/2021 10.1038/s42255-021-00478-5 34750571
PGP000490 1 1 Hatoum AS Multivariate genome-wide association meta-analysis of over 1 million subjects identifies loci underlying multiple substance use disorders. Nat Ment Health 22/03/2023 10.1038/s44220-023-00034-y 37250466
PGP000091 0 1 Ferrat LA A combined risk score enhances prediction of type 1 diabetes among susceptible children. Nat Med 07/08/2020 10.1038/s41591-020-0930-4 32770166
PGP000100 5 5 Mars N Polygenic and clinical risk scores and their impact on age at onset and prediction of cardiometabolic diseases and common cancers. Nat Med 07/04/2020 10.1038/s41591-020-0800-0 32273609
PGP000313 4 4 Kamiza AB Transferability of genetic risk scores in African populations. Nat Med 02/06/2022 10.1038/s41591-022-01835-x 35654908
PGP000269 1 1 Khan A Genome-wide polygenic score to predict chronic kidney disease across ancestries. Nat Med 16/06/2022 10.1038/s41591-022-01869-1 35710995
PGP000363 1 2 Sapkota Y Genetic risk score enhances the risk prediction of severe obesity in adult survivors of childhood cancer. Nat Med 25/07/2022 10.1038/s41591-022-01902-3 35879615
PGP000466 3 3 Patel AP A multi-ancestry polygenic risk score improves risk prediction for coronary artery disease. Nat Med 06/07/2023 10.1038/s41591-023-02429-x 37414900
PGP000446 1 3 Tcheandjieu C Large-scale genome-wide association study of coronary artery disease in genetically diverse populations. Nat Med 01/08/2022 10.1038/s41591-022-01891-3 35915156
PGP000412 2 2 Kachuri L Genetically adjusted PSA levels for prostate cancer screening. Nat Med 01/06/2023 10.1038/s41591-023-02277-9 37264206
PGP000462 3 3 Honigberg MC Polygenic prediction of preeclampsia and gestational hypertension. Nat Med 29/05/2023 10.1038/s41591-023-02374-9 37248299
PGP000381 0 6 Hao L Development of a clinical polygenic risk score assay and reporting workflow. Nat Med 18/04/2022 10.1038/s41591-022-01767-6 35437332
PGP000668 3 3 China Kadoorie Biobank Collaborative Group. Joint impact of polygenic risk score and lifestyles on early- and late-onset cardiovascular diseases. Nat Hum Behav 10/07/2024 10.1038/s41562-024-01923-7 38987358
PGP000390 1 1 Wuttke M A catalog of genetic loci associated with kidney function from analyses of a million individuals. Nat Genet 31/05/2019 10.1038/s41588-019-0407-x 31152163
PGP000246 3 3 Chen J The trans-ancestral genomic architecture of glycemic traits. Nat Genet 31/05/2021 10.1038/s41588-021-00852-9 34059833
PGP000030 1 1 Klarin D Genome-wide association analysis of venous thromboembolism identifies new risk loci and genetic overlap with arterial vascular disease. Nat Genet 01/11/2019 10.1038/s41588-019-0519-3 31676865
PGP000122 1 1 Conti DV Trans-ancestry genome-wide association meta-analysis of prostate cancer identifies new susceptibility loci and informs genetic risk prediction. Nat Genet 04/01/2021 10.1038/s41588-020-00748-0 33398198
PGP000357 1 1 Ishigaki K Multi-ancestry genome-wide association analyses identify novel genetic mechanisms in rheumatoid arthritis. Nat Genet 04/11/2022 10.1038/s41588-022-01213-w 36333501
PGP000061 1 1 MacGregor S Genome-wide association study of intraocular pressure uncovers new pathways to glaucoma. Nat Genet 27/07/2018 10.1038/s41588-018-0176-y 30054594
PGP000170 1 0 Huyghe JR Discovery of common and rare genetic risk variants for colorectal cancer. Nat Genet 03/12/2018 10.1038/s41588-018-0286-6 30510241
PGP000500 4 4 Shrine N Multi-ancestry genome-wide association analyses improve resolution of genes and pathways influencing lung function and chronic obstructive pulmonary disease risk. Nat Genet 13/03/2023 10.1038/s41588-023-01314-0 36914875
PGP000302 2 2 Horowitz JE Genome-wide analysis provides genetic evidence that ACE2 influences COVID-19 risk and yields risk scores associated with severe disease. Nat Genet 03/03/2022 10.1038/s41588-021-01006-7 35241825
PGP000341 1 1 Vujkovic M A multiancestry genome-wide association study of unexplained chronic ALT elevation as a proxy for nonalcoholic fatty liver disease with histological and radiological validation. Nat Genet 02/06/2022 10.1038/s41588-022-01078-z 35654975
PGP000593 6 6 Ojima T Body mass index stratification optimizes polygenic prediction of type 2 diabetes in cross-biobank analyses. Nat Genet 11/06/2024 10.1038/s41588-024-01782-y 38862855
PGP000211 33 34 Aly DM Genome-wide association analyses highlight etiological differences underlying newly defined subtypes of diabetes Nat Genet 04/11/2021 10.1038/s41588-021-00948-2 34737425
PGP000332 415 415 Weissbrod O Leveraging fine-mapping and multipopulation training data to improve cross-population polygenic risk scores. Nat Genet 07/04/2022 10.1038/s41588-022-01036-9 35393596
PGP000309 1 1 Bellenguez C New insights into the genetic etiology of Alzheimer's disease and related dementias. Nat Genet 04/04/2022 10.1038/s41588-022-01024-z 35379992
PGP000409 2 2 Aragam KG Discovery and systematic characterization of risk variants and genes for coronary artery disease in over a million participants. Nat Genet 06/12/2022 10.1038/s41588-022-01233-6 36474045
PGP000195 1 0 Ferreira MA Shared genetic origin of asthma, hay fever and eczema elucidates allergic disease biology. Nat Genet 30/10/2017 10.1038/ng.3985 29083406
PGP000088 5 7 Zhang H Genome-wide association study identifies 32 novel breast cancer susceptibility loci from overall and subtype-specific analyses. Nat Genet 18/05/2020 10.1038/s41588-020-0609-2 32424353
PGP000086 1 1 Shrine N New genetic signals for lung function highlight pathways and chronic obstructive pulmonary disease associations across multiple ancestries. Nat Genet 25/02/2019 10.1038/s41588-018-0321-7 30804560
PGP000296 1 1 Pirruccello JP Deep learning enables genetic analysis of the human thoracic aorta. Nat Genet 26/11/2021 10.1038/s41588-021-00962-4 34837083
PGP000182 1 2 Tadros R Shared genetic pathways contribute to risk of hypertrophic and dilated cardiomyopathies with opposite directions of effect. Nat Genet 25/01/2021 10.1038/s41588-020-00762-2 33495596
PGP000104 1 1 Koyama S Population-specific and trans-ancestry genome-wide analyses identify distinct and shared genetic risk loci for coronary artery disease. Nat Genet 05/10/2020 10.1038/s41588-020-0705-3 33020668
PGP000068 8 8 Cai N Minimal phenotyping yields genome-wide association signals of low specificity for major depression. Nat Genet 30/03/2020 10.1038/s41588-020-0594-5 32231276
PGP000464 132 132 Liu N Cross-ancestry genome-wide association meta-analyses of hippocampal and subfield volumes. Nat Genet 19/06/2023 10.1038/s41588-023-01425-8 37337106
PGP000066 1 1 Craig JE Multitrait analysis of glaucoma identifies new risk loci and enables polygenic prediction of disease susceptibility and progression. Nat Genet 20/01/2020 10.1038/s41588-019-0556-y 31959993
PGP000268 1 1 Tcheandjieu C High heritability of ascending aortic diameter and trans-ancestry prediction of thoracic aortic disease. Nat Genet 30/05/2022 10.1038/s41588-022-01070-7 35637384
PGP000098 1 1 Grove J Identification of common genetic risk variants for autism spectrum disorder. Nat Genet 25/02/2019 10.1038/s41588-019-0344-8 30804558
PGP000063 1 1 Tin A Target genes, variants, tissues and transcriptional pathways influencing human serum urate levels. Nat Genet 02/10/2019 10.1038/s41588-019-0504-x 31578528
PGP000146 1 1 Harper AR Common genetic variants and modifiable risk factors underpin hypertrophic cardiomyopathy susceptibility and expressivity. Nat Genet 25/01/2021 10.1038/s41588-020-00764-0 33495597
PGP000223 1 1 Lotta LA Integrative genomic analysis implicates limited peripheral adipose storage capacity in the pathogenesis of human insulin resistance. Nat Genet 14/11/2016 10.1038/ng.3714 27841877
PGP000181 1 1 Liu G Genome-wide survival study identifies a novel synaptic locus and polygenic score for cognitive progression in Parkinson's disease. Nat Genet 06/05/2021 10.1038/s41588-021-00847-6 33958783
PGP000260 1 1 Barc J Genome-wide association analyses identify new Brugada syndrome risk loci and highlight a new mechanism of sodium channel regulation in disease susceptibility. Nat Genet 24/02/2022 10.1038/s41588-021-01007-6 35210625
PGP000023 1 0 Mahajan A Fine-mapping type 2 diabetes loci to single-variant resolution using high-density imputation and islet-specific epigenome maps. Nat Genet 08/10/2018 10.1038/s41588-018-0241-6 30297969
PGP000491 1 0 Fernandez-Rozadilla C Deciphering colorectal cancer genetics through multi-omic analysis of 100,204 cases and 154,587 controls of European and east Asian ancestries. Nat Genet 20/12/2022 10.1038/s41588-022-01222-9 36539618
PGP000383 1 1 Solé-Navais P Genetic effects on the timing of parturition and links to fetal birth weight. Nat Genet 03/04/2023 10.1038/s41588-023-01343-9 37012456
PGP000489 82 82 Zhang H A new method for multiancestry polygenic prediction improves performance across diverse populations. Nat Genet 25/09/2023 10.1038/s41588-023-01501-z 37749244
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