PGS Publication: PGP000287

Publication Information (EuropePMC)
Title Genetic analysis in African American children supports ancestry specific neuroblastoma susceptibility.
PubMed ID 35131881(Europe PMC)
doi 10.1158/1055-9965.epi-21-0782
Publication Date Feb. 7, 2022
Journal Cancer Epidemiol Biomarkers Prev
Author(s) Testori A, Vaksman Z, Diskin SJ, Hakonarson H, Capasso M, Iolascon A, Maris JM, Devoto M.
Released in PGS Catalog: March 16, 2022

Associated Polygenic Score(s)

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Individuals included in:
G - Source of Variant Associations (GWAS)
D - Score Development/Training
E - PGS Evaluation
List of ancestries includes:
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Multi-ancestry (including European)
Multi-ancestry (excluding European)
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Additional Asian Ancestries
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Hispanic or Latin American
Additional Diverse Ancestries
Not Reported

PGS Developed By This Publication

Polygenic Score ID & Name PGS Publication ID (PGP) Reported Trait Mapped Trait(s) (Ontology) Number of Variants Ancestry distribution Scoring File (FTP Link)
PGP000287 |
Testori A et al. Cancer Epidemiol Biomarkers Prev (2022)
Neuroblastoma neuroblastoma 22

Performance Metrics

Disclaimer: The performance metrics are displayed as reported by the source studies. It is important to note that metrics are not necessarily comparable with each other. For example, metrics depend on the sample characteristics (described by the PGS Catalog Sample Set [PSS] ID), phenotyping, and statistical modelling. Please refer to the source publication for additional guidance on performance.

PGS Performance
Metric ID (PPM)
Evaluated Score PGS Sample Set ID
Performance Source Trait PGS Effect Sizes
(per SD change)
Classification Metrics Other Metrics Covariates Included in the Model PGS Performance:
Other Relevant Information
PPM012873 PGS002261
African Ancestry|
3,619 individuals
PGP000287 |
Testori A et al. Cancer Epidemiol Biomarkers Prev (2022)
Reported Trait: Neuroblastoma risk : 0.0203

Evaluated Samples

PGS Sample Set ID
Phenotype Definitions and Methods Participant Follow-up Time Sample Numbers Age of Study Participants Sample Ancestry Additional Ancestry Description Cohort(s) Additional Sample/Cohort Information
  • 629 cases
  • , 2,990 controls
African American or Afro-Caribbean
(African American)