PGS Publication: PGP000598

Publication Information (EuropePMC)
Title Low-level ambient sulfur dioxide exposure and genetic susceptibility associated with incidence of idiopathic pulmonary fibrosis: A national prospective cohort study.
PubMed ID 37414299(Europe PMC)
doi 10.1016/j.chemosphere.2023.139362
Publication Date July 4, 2023
Journal Chemosphere
Author(s) Wang X, Deng X, Wu Y, Qian Z, Cai M, Li H, Lin H.
Released in PGS Catalog: March 18, 2024

Associated Polygenic Score(s)

Filter PGS by Participant Ancestry
Individuals included in:
G - Source of Variant Associations (GWAS)
D - Score Development/Training
E - PGS Evaluation
List of ancestries includes:
Display options:
Ancestry legend
Multi-ancestry (including European)
Multi-ancestry (excluding European)
East Asian
South Asian
Additional Asian Ancestries
Greater Middle Eastern
Hispanic or Latin American
Additional Diverse Ancestries
Not Reported

PGS Developed By This Publication

Polygenic Score ID & Name PGS Publication ID (PGP) Reported Trait Mapped Trait(s) (Ontology) Number of Variants Ancestry distribution
Scoring File (FTP Link)
PGP000598 |
Wang X et al. Chemosphere (2023)
Idiopathic pulmonary fibrosis idiopathic pulmonary fibrosis 23

Performance Metrics

Disclaimer: The performance metrics are displayed as reported by the source studies. It is important to note that metrics are not necessarily comparable with each other. For example, metrics depend on the sample characteristics (described by the PGS Catalog Sample Set [PSS] ID), phenotyping, and statistical modelling. Please refer to the source publication for additional guidance on performance.

PGS Performance
Metric ID (PPM)
Evaluated Score PGS Sample Set ID
Performance Source Trait PGS Effect Sizes
(per SD change)
Classification Metrics Other Metrics Covariates Included in the Model PGS Performance:
Other Relevant Information
PPM020881 PGS004695
European Ancestry|
402,042 individuals
PGP000598 |
Wang X et al. Chemosphere (2023)
Reported Trait: Incident idiopathic pulmonary fibrosis Hazard ratio (HR, high vs low PRS quintile): 3.78 [3.3, 4.34] Age, sex, education level, smoking status, pack-years of smoking, BMI

Evaluated Samples

PGS Sample Set ID
Phenotype Definitions and Methods Participant Follow-up Time Sample Numbers Age of Study Participants Sample Ancestry Additional Ancestry Description Cohort(s) Additional Sample/Cohort Information
PSS011440 Median = 11.78 years
  • 2,589 cases
  • , 399,453 controls
46.66 % Male samples
Mean = 56.41 years
Sd = 8.04 years
European UKB