Polygenic Score (PGS) ID: PGS001235

Predicted Trait
Reported Trait Right arm mass (predicted)
Mapped Trait(s) body weights and measures (EFO_0004324)
Additional Trait Information https://biobankengine.stanford.edu/RIVAS_HG19/snpnet/INI23122
Released in PGS Catalog: Oct. 21, 2021
Download Score FTP directory
Terms and Licenses
PGS obtained from the Catalog should be cited appropriately, and used in accordance with any licensing restrictions set by the authors. See EBI Terms of Use (https://www.ebi.ac.uk/about/terms-of-use/) for additional details.

Score Details

Score Construction
PGS Name GBE_INI23122
Development Method
Name snpnet
Parameters NR
Variants
Original Genome Build GRCh37
Number of Variants 28,988
Effect Weight Type NR
PGS Source
PGS Catalog Publication (PGP) ID PGP000244
Citation (link to publication) Tanigawa Y et al. PLoS Genet (2022)
Ancestry Distribution
Score Development/Training
European: 100%
265,099 individuals (100%)
PGS Evaluation
European: 40%
African: 20%
East Asian: 20%
South Asian: 20%
5 Sample Sets

Development Samples

Score Development/Training
Study Identifiers Sample Numbers Sample Ancestry Cohort(s) Phenotype Definitions & Methods Age of Study Participants Participant Follow-up Time Additional Ancestry Description Additional Sample/Cohort Information
— 265,099 individuals European UKB — — — white British ancestry —

Performance Metrics

Disclaimer: The performance metrics are displayed as reported by the source studies. It is important to note that metrics are not necessarily comparable with each other. For example, metrics depend on the sample characteristics (described by the PGS Catalog Sample Set [PSS] ID), phenotyping, and statistical modelling. Please refer to the source publication for additional guidance on performance.

PGS Performance
Metric ID (PPM) 		PGS Sample Set ID
(PSS) 		Performance Source Trait PGS Effect Sizes
(per SD change) 		Classification Metrics Other Metrics Covariates Included in the Model PGS Performance:
Other Relevant Information
PPM008684 PSS005136|
African Ancestry|
6,302 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: Arm pred. mass (R) — — R²: 0.65534 [0.64178, 0.6689]
Incremental R2 (full-covars): 0.00854
PGS R2 (no covariates): 0.01485 [0.00901, 0.02068]		 age, sex, UKB array type, Genotype PCs —
PPM008685 PSS005137|
East Asian Ancestry|
1,678 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: Arm pred. mass (R) — — R²: 0.7677 [0.74842, 0.78699]
Incremental R2 (full-covars): 0.002
PGS R2 (no covariates): 0.0134 [0.00258, 0.02423]		 age, sex, UKB array type, Genotype PCs —
PPM008686 PSS005138|
European Ancestry|
24,458 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: Arm pred. mass (R) — — R²: 0.76826 [0.76321, 0.7733]
Incremental R2 (full-covars): 0.03558
PGS R2 (no covariates): 0.03693 [0.03233, 0.04152]		 age, sex, UKB array type, Genotype PCs —
PPM008687 PSS005139|
South Asian Ancestry|
7,648 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: Arm pred. mass (R) — — R²: 0.7148 [0.70413, 0.72548]
Incremental R2 (full-covars): 0.02639
PGS R2 (no covariates): 0.01722 [0.01151, 0.02293]		 age, sex, UKB array type, Genotype PCs —
PPM008688 PSS005140|
European Ancestry|
66,247 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: Arm pred. mass (R) — — R²: 0.76233 [0.7592, 0.76546]
Incremental R2 (full-covars): 0.03907
PGS R2 (no covariates): 0.03932 [0.03645, 0.0422]		 age, sex, UKB array type, Genotype PCs —

Evaluated Samples

PGS Sample Set ID
(PSS) 		Phenotype Definitions and Methods Participant Follow-up Time Sample Numbers Age of Study Participants Sample Ancestry Additional Ancestry Description Cohort(s) Additional Sample/Cohort Information
PSS005136 — — 6,302 individuals — African unspecified — UKB —
PSS005137 — — 1,678 individuals — East Asian — UKB —
PSS005138 — — 24,458 individuals — European non-white British ancestry UKB —
PSS005139 — — 7,648 individuals — South Asian — UKB —
PSS005140 — — 66,247 individuals — European white British ancestry UKB Testing cohort (heldout set)