Polygenic Score (PGS) ID: PGS001919

Predicted Trait
Reported Trait Fluid intelligence score
Mapped Trait(s) intelligence (EFO_0004337)
Additional Trait Information physical measures
Released in PGS Catalog: Jan. 10, 2022
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Score Details

Score Construction
PGS Name portability-PLR_fluid_intelligence
Development Method
Name Penalized regression (bigstatsr)
Parameters HapMap3 variants
Variants
Original Genome Build GRCh37
Number of Variants 26,145
Effect Weight Type beta
PGS Source
PGS Catalog Publication (PGP) ID PGP000263
Citation (link to publication) Privé F et al. Am J Hum Genet (2022)
Ancestry Distribution
Score Development/Training
European: 100%
391,124 individuals (100%)
PGS Evaluation
European: 37.5%
African: 25%
East Asian: 12.5%
Greater Middle Eastern: 12.5%
South Asian: 12.5%
8 Sample Sets

Development Samples

Score Development/Training
Phenotype Definitions and Methods Participant Follow-up Time Sample Numbers Age of Study Participants Sample Ancestry Additional Ancestry Description Cohort(s) Additional Sample/Cohort Information
391,124 individuals European UK (+ Ireland) UKB

Performance Metrics

Disclaimer: The performance metrics are displayed as reported by the source studies. It is important to note that metrics are not necessarily comparable with each other. For example, metrics depend on the sample characteristics (described by the PGS Catalog Sample Set [PSS] ID), phenotyping, and statistical modelling. Please refer to the source publication for additional guidance on performance.

PGS Performance
Metric ID (PPM)
PGS Sample Set ID
(PSS)
Performance Source Trait PGS Effect Sizes
(per SD change)
Classification Metrics Other Metrics Covariates Included in the Model PGS Performance:
Other Relevant Information
PPM010231 PSS009406|
European Ancestry|
5,092 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Fluid intelligence score Partial Correlation (partial-r): 0.1628 [0.1359, 0.1895] sex, age, birth date, deprivation index, 16 PCs
PPM010232 PSS009180|
European Ancestry|
984 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Fluid intelligence score Partial Correlation (partial-r): 0.0669 [0.0038, 0.1295] sex, age, birth date, deprivation index, 16 PCs
PPM010233 PSS008734|
European Ancestry|
1,846 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Fluid intelligence score Partial Correlation (partial-r): 0.1731 [0.1282, 0.2172] sex, age, birth date, deprivation index, 16 PCs
PPM010235 PSS008286|
South Asian Ancestry|
653 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Fluid intelligence score Partial Correlation (partial-r): 0.1605 [0.0836, 0.2354] sex, age, birth date, deprivation index, 16 PCs
PPM010236 PSS008063|
East Asian Ancestry|
345 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Fluid intelligence score Partial Correlation (partial-r): 0.0626 [-0.0465, 0.1703] sex, age, birth date, deprivation index, 16 PCs
PPM010237 PSS007850|
African Ancestry|
266 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Fluid intelligence score Partial Correlation (partial-r): 0.1082 [-0.0171, 0.2302] sex, age, birth date, deprivation index, 16 PCs
PPM010238 PSS008954|
African Ancestry|
323 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Fluid intelligence score Partial Correlation (partial-r): 0.0768 [-0.0362, 0.1879] sex, age, birth date, deprivation index, 16 PCs
PPM010234 PSS008508|
Greater Middle Eastern Ancestry|
158 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Fluid intelligence score Partial Correlation (partial-r): 0.1171 [-0.051, 0.2788] sex, age, birth date, deprivation index, 16 PCs

Evaluated Samples

PGS Sample Set ID
(PSS)
Phenotype Definitions and Methods Participant Follow-up Time Sample Numbers Age of Study Participants Sample Ancestry Additional Ancestry Description Cohort(s) Additional Sample/Cohort Information
PSS008508 158 individuals Greater Middle Eastern (Middle Eastern, North African or Persian) Iran (Middle East) UKB
PSS007850 266 individuals African American or Afro-Caribbean Carribean UKB
PSS008286 653 individuals South Asian India (South Asia) UKB
PSS008734 1,846 individuals European Italy (South Europe) UKB
PSS008954 323 individuals African unspecified Nigeria (West Africa) UKB
PSS009180 984 individuals European Poland (NE Europe) UKB
PSS009406 5,092 individuals European UK (+ Ireland) UKB
PSS008063 345 individuals East Asian China (East Asia) UKB