Polygenic Score (PGS) ID: PGS001958

Predicted Trait
Reported Trait Hip circumference
Mapped Trait(s) hip circumference (EFO_0005093)
Additional Trait Information physical measures
Released in PGS Catalog: Jan. 10, 2022
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Score Details

Score Construction
PGS Name portability-PLR_log_hip_circ
Development Method
Name Penalized regression (bigstatsr)
Parameters HapMap3 variants
Variants
Original Genome Build GRCh37
Number of Variants 103,123
Effect Weight Type beta
PGS Source
PGS Catalog Publication (PGP) ID PGP000263
Citation (link to publication) Privé F et al. Am J Hum Genet (2022)
Ancestry Distribution
Score Development/Training
European: 100%
391,124 individuals (100%)
PGS Evaluation
European: 37.5%
African: 25%
East Asian: 12.5%
Greater Middle Eastern: 12.5%
South Asian: 12.5%
8 Sample Sets

Development Samples

Score Development/Training
Phenotype Definitions and Methods Participant Follow-up Time Sample Numbers Age of Study Participants Sample Ancestry Additional Ancestry Description Cohort(s) Additional Sample/Cohort Information
391,124 individuals European UK (+ Ireland) UKB

Performance Metrics

Disclaimer: The performance metrics are displayed as reported by the source studies. It is important to note that metrics are not necessarily comparable with each other. For example, metrics depend on the sample characteristics (described by the PGS Catalog Sample Set [PSS] ID), phenotyping, and statistical modelling. Please refer to the source publication for additional guidance on performance.

PGS Performance
Metric ID (PPM)
PGS Sample Set ID
(PSS)
Performance Source Trait PGS Effect Sizes
(per SD change)
Classification Metrics Other Metrics Covariates Included in the Model PGS Performance:
Other Relevant Information
PPM010539 PSS009449|
European Ancestry|
19,965 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Hip circumference Partial Correlation (partial-r): 0.3373 [0.3249, 0.3495] sex, age, birth date, deprivation index, 16 PCs
PPM010540 PSS009223|
European Ancestry|
4,125 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Hip circumference Partial Correlation (partial-r): 0.3442 [0.317, 0.3709] sex, age, birth date, deprivation index, 16 PCs
PPM010541 PSS008777|
European Ancestry|
6,637 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Hip circumference Partial Correlation (partial-r): 0.3192 [0.2974, 0.3407] sex, age, birth date, deprivation index, 16 PCs
PPM010542 PSS008551|
Greater Middle Eastern Ancestry|
1,181 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Hip circumference Partial Correlation (partial-r): 0.3169 [0.2642, 0.3677] sex, age, birth date, deprivation index, 16 PCs
PPM010543 PSS008329|
South Asian Ancestry|
6,267 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Hip circumference Partial Correlation (partial-r): 0.284 [0.261, 0.3066] sex, age, birth date, deprivation index, 16 PCs
PPM010544 PSS008106|
East Asian Ancestry|
1,802 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Hip circumference Partial Correlation (partial-r): 0.2472 [0.2031, 0.2903] sex, age, birth date, deprivation index, 16 PCs
PPM010545 PSS007893|
African Ancestry|
2,456 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Hip circumference Partial Correlation (partial-r): 0.1739 [0.1351, 0.2121] sex, age, birth date, deprivation index, 16 PCs
PPM010546 PSS008997|
African Ancestry|
3,867 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Hip circumference Partial Correlation (partial-r): 0.1434 [0.1123, 0.1742] sex, age, birth date, deprivation index, 16 PCs

Evaluated Samples

PGS Sample Set ID
(PSS)
Phenotype Definitions and Methods Participant Follow-up Time Sample Numbers Age of Study Participants Sample Ancestry Additional Ancestry Description Cohort(s) Additional Sample/Cohort Information
PSS008997 3,867 individuals African unspecified Nigeria (West Africa) UKB
PSS009223 4,125 individuals European Poland (NE Europe) UKB
PSS008551 1,181 individuals Greater Middle Eastern (Middle Eastern, North African or Persian) Iran (Middle East) UKB
PSS008329 6,267 individuals South Asian India (South Asia) UKB
PSS009449 19,965 individuals European UK (+ Ireland) UKB
PSS008777 6,637 individuals European Italy (South Europe) UKB
PSS008106 1,802 individuals East Asian China (East Asia) UKB
PSS007893 2,456 individuals African American or Afro-Caribbean Carribean UKB