Polygenic Score (PGS) ID: PGS002002

Predicted Trait
Reported Trait Hair colour (natural, before greying)
Mapped Trait(s) hair colour measurement (EFO_0007822)
Additional Trait Information physical measures
Released in PGS Catalog: Jan. 10, 2022
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Score Details

Score Construction
PGS Name portability-PLR_red_hair
Development Method
Name Penalized regression (bigstatsr)
Parameters HapMap3 variants
Variants
Original Genome Build GRCh37
Number of Variants 2,755
Effect Weight Type beta
PGS Source
PGS Catalog Publication (PGP) ID PGP000263
Citation (link to publication) Privé F et al. Am J Hum Genet (2022)
Ancestry Distribution
Score Development/Training
European: 100%
391,124 individuals (100%)
PGS Evaluation
European: 42.9%
African: 28.6%
Greater Middle Eastern: 14.3%
South Asian: 14.3%
7 Sample Sets

Development Samples

Score Development/Training
Phenotype Definitions and Methods Participant Follow-up Time Sample Numbers Age of Study Participants Sample Ancestry Additional Ancestry Description Cohort(s) Additional Sample/Cohort Information
391,124 individuals European UK (+ Ireland) UKB

Performance Metrics

Disclaimer: The performance metrics are displayed as reported by the source studies. It is important to note that metrics are not necessarily comparable with each other. For example, metrics depend on the sample characteristics (described by the PGS Catalog Sample Set [PSS] ID), phenotyping, and statistical modelling. Please refer to the source publication for additional guidance on performance.

PGS Performance
Metric ID (PPM)
PGS Sample Set ID
(PSS)
Performance Source Trait PGS Effect Sizes
(per SD change)
Classification Metrics Other Metrics Covariates Included in the Model PGS Performance:
Other Relevant Information
PPM010892 PSS009260|
European Ancestry|
4,046 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Hair colour (natural, before greying) Partial Correlation (partial-r): 0.3044 [0.2761, 0.3322] sex, age, birth date, deprivation index, 16 PCs
PPM010893 PSS008814|
European Ancestry|
6,570 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Hair colour (natural, before greying) Partial Correlation (partial-r): 0.29 [0.2676, 0.312] sex, age, birth date, deprivation index, 16 PCs
PPM010894 PSS008588|
Greater Middle Eastern Ancestry|
1,135 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Hair colour (natural, before greying) Partial Correlation (partial-r): 0.2119 [0.1551, 0.2673] sex, age, birth date, deprivation index, 16 PCs
PPM010895 PSS008366|
South Asian Ancestry|
6,131 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Hair colour (natural, before greying) Partial Correlation (partial-r): 0.0255 sex, age, birth date, deprivation index, 16 PCs
PPM010896 PSS007930|
African Ancestry|
2,419 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Hair colour (natural, before greying) Partial Correlation (partial-r): -0.0053 [-0.0453, 0.0347] sex, age, birth date, deprivation index, 16 PCs
PPM010897 PSS009034|
African Ancestry|
3,836 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Hair colour (natural, before greying) Partial Correlation (partial-r): -0.0153 [-0.0471, 0.0164] sex, age, birth date, deprivation index, 16 PCs
PPM010891 PSS009486|
European Ancestry|
19,713 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Hair colour (natural, before greying) Partial Correlation (partial-r): 0.4238 [0.4123, 0.4352] sex, age, birth date, deprivation index, 16 PCs

Evaluated Samples

PGS Sample Set ID
(PSS)
Phenotype Definitions and Methods Participant Follow-up Time Sample Numbers Age of Study Participants Sample Ancestry Additional Ancestry Description Cohort(s) Additional Sample/Cohort Information
PSS009034 3,836 individuals African unspecified Nigeria (West Africa) UKB
PSS009260 4,046 individuals European Poland (NE Europe) UKB
PSS008588 1,135 individuals Greater Middle Eastern (Middle Eastern, North African or Persian) Iran (Middle East) UKB
PSS008366 6,131 individuals South Asian India (South Asia) UKB
PSS008814 6,570 individuals European Italy (South Europe) UKB
PSS009486 19,713 individuals European UK (+ Ireland) UKB
PSS007930 2,419 individuals African American or Afro-Caribbean Carribean UKB