Polygenic Score (PGS) ID: PGS002012

Predicted Trait
Reported Trait Qualifications (years of education)
Mapped Trait(s) educational attainment (EFO_0011015)
Additional Trait Information lifestyle and environment
Released in PGS Catalog: Jan. 10, 2022
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Score Details

Score Construction
PGS Name portability-PLR_years_of_edu
Development Method
Name Penalized regression (bigstatsr)
Parameters HapMap3 variants
Variants
Original Genome Build GRCh37
Number of Variants 50,413
Effect Weight Type beta
PGS Source
PGS Catalog Publication (PGP) ID PGP000263
Citation (link to publication) Privé F et al. Am J Hum Genet (2022)
Ancestry Distribution
Score Development/Training
European: 100%
391,124 individuals (100%)
PGS Evaluation
European: 44.4%
African: 22.2%
East Asian: 11.1%
Greater Middle Eastern: 11.1%
South Asian: 11.1%
9 Sample Sets

Development Samples

Score Development/Training
Study Identifiers Sample Numbers Sample Ancestry Cohort(s) Phenotype Definitions & Methods Age of Study Participants Participant Follow-up Time Additional Ancestry Description Additional Sample/Cohort Information
— 391,124 individuals European UKB — — — UK (+ Ireland) —

Performance Metrics

Disclaimer: The performance metrics are displayed as reported by the source studies. It is important to note that metrics are not necessarily comparable with each other. For example, metrics depend on the sample characteristics (described by the PGS Catalog Sample Set [PSS] ID), phenotyping, and statistical modelling. Please refer to the source publication for additional guidance on performance.

PGS Performance
Metric ID (PPM) 		PGS Sample Set ID
(PSS) 		Performance Source Trait PGS Effect Sizes
(per SD change) 		Classification Metrics Other Metrics Covariates Included in the Model PGS Performance:
Other Relevant Information
PPM010970 PSS009497|
European Ancestry|
16,350 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Qualifications (years of education) — — Partial Correlation (partial-r): 0.1752 [0.1603, 0.19] sex, age, birth date, deprivation index, 16 PCs —
PPM010971 PSS009271|
European Ancestry|
3,619 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Qualifications (years of education) — — Partial Correlation (partial-r): 0.1351 [0.1029, 0.167] sex, age, birth date, deprivation index, 16 PCs —
PPM010973 PSS008599|
Greater Middle Eastern Ancestry|
957 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Qualifications (years of education) — — Partial Correlation (partial-r): 0.0796 [0.0156, 0.1429] sex, age, birth date, deprivation index, 16 PCs —
PPM010974 PSS008377|
South Asian Ancestry|
4,749 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Qualifications (years of education) — — Partial Correlation (partial-r): 0.0946 [0.0662, 0.1227] sex, age, birth date, deprivation index, 16 PCs —
PPM010975 PSS008153|
East Asian Ancestry|
1,520 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Qualifications (years of education) — — Partial Correlation (partial-r): 0.0155 [-0.0352, 0.066] sex, age, birth date, deprivation index, 16 PCs —
PPM010976 PSS007941|
African Ancestry|
1,949 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Qualifications (years of education) — — Partial Correlation (partial-r): 0.0297 [-0.0149, 0.0742] sex, age, birth date, deprivation index, 16 PCs —
PPM010977 PSS009045|
African Ancestry|
3,278 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Qualifications (years of education) — — Partial Correlation (partial-r): 0.028 [-0.0063, 0.0623] sex, age, birth date, deprivation index, 16 PCs —
PPM010972 PSS008825|
European Ancestry|
5,612 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Qualifications (years of education) — — Partial Correlation (partial-r): 0.1582 [0.1326, 0.1837] sex, age, birth date, deprivation index, 16 PCs —
PPM039227 PSS013916|
European Ancestry|
425,240 individuals
 PGP000865 |
Bhatt IS et al. J Assoc Res Otolaryngol (2024)
|Ext.		 Reported Trait: Age-related hearing difficulty β: -0.00905 — — — —

Evaluated Samples

PGS Sample Set ID
(PSS) 		Phenotype Definitions and Methods Participant Follow-up Time Sample Numbers Age of Study Participants Sample Ancestry Additional Ancestry Description Cohort(s) Additional Sample/Cohort Information
PSS007941 — — 1,949 individuals — African American or Afro-Caribbean Carribean UKB —
PSS009045 — — 3,278 individuals — African unspecified Nigeria (West Africa) UKB —
PSS009271 — — 3,619 individuals — European Poland (NE Europe) UKB —
PSS008599 — — 957 individuals — Greater Middle Eastern (Middle Eastern, North African or Persian) Iran (Middle East) UKB —
PSS008377 — — 4,749 individuals — South Asian India (South Asia) UKB —
PSS008153 — — 1,520 individuals — East Asian China (East Asia) UKB —
PSS009497 — — 16,350 individuals — European UK (+ Ireland) UKB —
PSS008825 — — 5,612 individuals — European Italy (South Europe) UKB —
PSS013916 — —
[
  • 111,243 cases
  • , 313,997 controls
]
,
46.21 % Male samples
 — European
(British, Irish)		 — UKB —