Polygenic Score (PGS) ID: PGS002012

Predicted Trait
Reported Trait Qualifications (years of education)
Mapped Trait(s) educational attainment (EFO_0011015)
Additional Trait Information lifestyle and environment
Released in PGS Catalog: Jan. 10, 2022
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Score Details

Score Construction
PGS Name portability-PLR_years_of_edu
Development Method
Name Penalized regression (bigstatsr)
Parameters HapMap3 variants
Variants
Original Genome Build GRCh37
Number of Variants 50,413
Effect Weight Type beta
PGS Source
PGS Catalog Publication (PGP) ID PGP000263
Citation (link to publication) Privé F et al. Am J Hum Genet (2022)
Ancestry Distribution
Score Development/Training
European: 100%
391,124 individuals (100%)
PGS Evaluation
European: 37.5%
African: 25%
East Asian: 12.5%
Greater Middle Eastern: 12.5%
South Asian: 12.5%
8 Sample Sets

Development Samples

Score Development/Training
Phenotype Definitions and Methods Participant Follow-up Time Sample Numbers Age of Study Participants Sample Ancestry Additional Ancestry Description Cohort(s) Additional Sample/Cohort Information
391,124 individuals European UK (+ Ireland) UKB

Performance Metrics

Disclaimer: The performance metrics are displayed as reported by the source studies. It is important to note that metrics are not necessarily comparable with each other. For example, metrics depend on the sample characteristics (described by the PGS Catalog Sample Set [PSS] ID), phenotyping, and statistical modelling. Please refer to the source publication for additional guidance on performance.

PGS Performance
Metric ID (PPM)
PGS Sample Set ID
(PSS)
Performance Source Trait PGS Effect Sizes
(per SD change)
Classification Metrics Other Metrics Covariates Included in the Model PGS Performance:
Other Relevant Information
PPM010970 PSS009497|
European Ancestry|
16,350 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Qualifications (years of education) Partial Correlation (partial-r): 0.1752 [0.1603, 0.19] sex, age, birth date, deprivation index, 16 PCs
PPM010971 PSS009271|
European Ancestry|
3,619 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Qualifications (years of education) Partial Correlation (partial-r): 0.1351 [0.1029, 0.167] sex, age, birth date, deprivation index, 16 PCs
PPM010973 PSS008599|
Greater Middle Eastern Ancestry|
957 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Qualifications (years of education) Partial Correlation (partial-r): 0.0796 [0.0156, 0.1429] sex, age, birth date, deprivation index, 16 PCs
PPM010974 PSS008377|
South Asian Ancestry|
4,749 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Qualifications (years of education) Partial Correlation (partial-r): 0.0946 [0.0662, 0.1227] sex, age, birth date, deprivation index, 16 PCs
PPM010975 PSS008153|
East Asian Ancestry|
1,520 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Qualifications (years of education) Partial Correlation (partial-r): 0.0155 [-0.0352, 0.066] sex, age, birth date, deprivation index, 16 PCs
PPM010976 PSS007941|
African Ancestry|
1,949 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Qualifications (years of education) Partial Correlation (partial-r): 0.0297 [-0.0149, 0.0742] sex, age, birth date, deprivation index, 16 PCs
PPM010977 PSS009045|
African Ancestry|
3,278 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Qualifications (years of education) Partial Correlation (partial-r): 0.028 [-0.0063, 0.0623] sex, age, birth date, deprivation index, 16 PCs
PPM010972 PSS008825|
European Ancestry|
5,612 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Qualifications (years of education) Partial Correlation (partial-r): 0.1582 [0.1326, 0.1837] sex, age, birth date, deprivation index, 16 PCs

Evaluated Samples

PGS Sample Set ID
(PSS)
Phenotype Definitions and Methods Participant Follow-up Time Sample Numbers Age of Study Participants Sample Ancestry Additional Ancestry Description Cohort(s) Additional Sample/Cohort Information
PSS007941 1,949 individuals African American or Afro-Caribbean Carribean UKB
PSS009045 3,278 individuals African unspecified Nigeria (West Africa) UKB
PSS009271 3,619 individuals European Poland (NE Europe) UKB
PSS008599 957 individuals Greater Middle Eastern (Middle Eastern, North African or Persian) Iran (Middle East) UKB
PSS008377 4,749 individuals South Asian India (South Asia) UKB
PSS008153 1,520 individuals East Asian China (East Asia) UKB
PSS009497 16,350 individuals European UK (+ Ireland) UKB
PSS008825 5,612 individuals European Italy (South Europe) UKB