Polygenic Score (PGS) ID: PGS002148

Predicted Trait
Reported Trait Average total household income before tax
Mapped Trait(s) household income (EFO_0009695)
Additional Trait Information lifestyle and environment
Released in PGS Catalog: Jan. 10, 2022
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Score Details

Score Construction
PGS Name portability-ldpred2_income
Development Method
Name LDpred2 (bigsnpr)
Parameters LDpred2-auto using HapMap3 variants
Variants
Original Genome Build GRCh37
Number of Variants 932,197
Effect Weight Type beta
PGS Source
PGS Catalog Publication (PGP) ID PGP000263
Citation (link to publication) Privé F et al. Am J Hum Genet (2022)
Ancestry Distribution
Score Development/Training
European: 100%
391,124 individuals (100%)
PGS Evaluation
European: 37.5%
African: 25%
East Asian: 12.5%
Greater Middle Eastern: 12.5%
South Asian: 12.5%
8 Sample Sets

Development Samples

Score Development/Training
Study Identifiers Sample Numbers Sample Ancestry Cohort(s) Phenotype Definitions & Methods Age of Study Participants Participant Follow-up Time Additional Ancestry Description Additional Sample/Cohort Information
— 391,124 individuals European UKB — — — UK (+ Ireland) —

Performance Metrics

Disclaimer: The performance metrics are displayed as reported by the source studies. It is important to note that metrics are not necessarily comparable with each other. For example, metrics depend on the sample characteristics (described by the PGS Catalog Sample Set [PSS] ID), phenotyping, and statistical modelling. Please refer to the source publication for additional guidance on performance.

PGS Performance
Metric ID (PPM) 		PGS Sample Set ID
(PSS) 		Performance Source Trait PGS Effect Sizes
(per SD change) 		Classification Metrics Other Metrics Covariates Included in the Model PGS Performance:
Other Relevant Information
PPM012031 PSS009418|
European Ancestry|
17,147 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Average total household income before tax — — Partial Correlation (partial-r): 0.1679 [0.1533, 0.1824] sex, age, birth date, deprivation index, 16 PCs —
PPM012038 PSS008966|
African Ancestry|
2,881 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Average total household income before tax — — Partial Correlation (partial-r): 0.067 [0.0304, 0.1033] sex, age, birth date, deprivation index, 16 PCs —
PPM012032 PSS009192|
European Ancestry|
3,467 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Average total household income before tax — — Partial Correlation (partial-r): 0.1185 [0.0855, 0.1513] sex, age, birth date, deprivation index, 16 PCs —
PPM012033 PSS008746|
European Ancestry|
5,619 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Average total household income before tax — — Partial Correlation (partial-r): 0.1531 [0.1274, 0.1786] sex, age, birth date, deprivation index, 16 PCs —
PPM012034 PSS008520|
Greater Middle Eastern Ancestry|
809 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Average total household income before tax — — Partial Correlation (partial-r): 0.0961 [0.0265, 0.1648] sex, age, birth date, deprivation index, 16 PCs —
PPM012035 PSS008298|
South Asian Ancestry|
4,548 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Average total household income before tax — — Partial Correlation (partial-r): 0.1012 [0.0723, 0.1299] sex, age, birth date, deprivation index, 16 PCs —
PPM012036 PSS008075|
East Asian Ancestry|
1,404 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Average total household income before tax — — Partial Correlation (partial-r): 0.0189 [-0.0338, 0.0716] sex, age, birth date, deprivation index, 16 PCs —
PPM012037 PSS007862|
African Ancestry|
1,874 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Average total household income before tax — — Partial Correlation (partial-r): 0.0188 [-0.0267, 0.0643] sex, age, birth date, deprivation index, 16 PCs —

Evaluated Samples

PGS Sample Set ID
(PSS) 		Phenotype Definitions and Methods Participant Follow-up Time Sample Numbers Age of Study Participants Sample Ancestry Additional Ancestry Description Cohort(s) Additional Sample/Cohort Information
PSS008966 — — 2,881 individuals — African unspecified Nigeria (West Africa) UKB —
PSS008520 — — 809 individuals — Greater Middle Eastern (Middle Eastern, North African or Persian) Iran (Middle East) UKB —
PSS009192 — — 3,467 individuals — European Poland (NE Europe) UKB —
PSS008746 — — 5,619 individuals — European Italy (South Europe) UKB —
PSS009418 — — 17,147 individuals — European UK (+ Ireland) UKB —
PSS008298 — — 4,548 individuals — South Asian India (South Asia) UKB —
PSS008075 — — 1,404 individuals — East Asian China (East Asia) UKB —
PSS007862 — — 1,874 individuals — African American or Afro-Caribbean Carribean UKB —