Polygenic Score (PGS) ID: PGS002225

Predicted Trait
Reported Trait Snoring
Mapped Trait(s) snoring measurement (EFO_0008341)
Additional Trait Information physical measures
Released in PGS Catalog: Jan. 10, 2022
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Score Details

Score Construction
PGS Name portability-ldpred2_snoring
Development Method
Name LDpred2 (bigsnpr)
Parameters LDpred2-auto using HapMap3 variants
Variants
Original Genome Build GRCh37
Number of Variants 913,306
Effect Weight Type beta
PGS Source
PGS Catalog Publication (PGP) ID PGP000263
Citation (link to publication) Privé F et al. Am J Hum Genet (2022)
Ancestry Distribution
Score Development/Training
European: 100%
391,124 individuals (100%)
PGS Evaluation
European: 37.5%
African: 25%
East Asian: 12.5%
Greater Middle Eastern: 12.5%
South Asian: 12.5%
8 Sample Sets

Development Samples

Score Development/Training
Study Identifiers Sample Numbers Sample Ancestry Cohort(s) Phenotype Definitions & Methods Age of Study Participants Participant Follow-up Time Additional Ancestry Description Additional Sample/Cohort Information
— 391,124 individuals European UKB — — — UK (+ Ireland) —

Performance Metrics

Disclaimer: The performance metrics are displayed as reported by the source studies. It is important to note that metrics are not necessarily comparable with each other. For example, metrics depend on the sample characteristics (described by the PGS Catalog Sample Set [PSS] ID), phenotyping, and statistical modelling. Please refer to the source publication for additional guidance on performance.

PGS Performance
Metric ID (PPM) 		PGS Sample Set ID
(PSS) 		Performance Source Trait PGS Effect Sizes
(per SD change) 		Classification Metrics Other Metrics Covariates Included in the Model PGS Performance:
Other Relevant Information
PPM012646 PSS009491|
European Ancestry|
18,616 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Snoring — — Partial Correlation (partial-r): 0.1313 [0.1171, 0.1454] sex, age, birth date, deprivation index, 16 PCs —
PPM012647 PSS009265|
European Ancestry|
3,654 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Snoring — — Partial Correlation (partial-r): 0.1156 [0.0834, 0.1476] sex, age, birth date, deprivation index, 16 PCs —
PPM012648 PSS008819|
European Ancestry|
6,027 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Snoring — — Partial Correlation (partial-r): 0.1151 [0.0901, 0.14] sex, age, birth date, deprivation index, 16 PCs —
PPM012649 PSS008593|
Greater Middle Eastern Ancestry|
1,011 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Snoring — — Partial Correlation (partial-r): 0.0971 [0.0351, 0.1584] sex, age, birth date, deprivation index, 16 PCs —
PPM012650 PSS008371|
South Asian Ancestry|
5,655 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Snoring — — Partial Correlation (partial-r): 0.0904 [0.0644, 0.1162] sex, age, birth date, deprivation index, 16 PCs —
PPM012651 PSS008147|
East Asian Ancestry|
1,576 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Snoring — — Partial Correlation (partial-r): 0.0901 [0.0406, 0.1392] sex, age, birth date, deprivation index, 16 PCs —
PPM012652 PSS007935|
African Ancestry|
2,178 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Snoring — — Partial Correlation (partial-r): 0.0722 [0.0301, 0.114] sex, age, birth date, deprivation index, 16 PCs —
PPM012653 PSS009039|
African Ancestry|
3,448 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Snoring — — Partial Correlation (partial-r): 0.0754 [0.042, 0.1086] sex, age, birth date, deprivation index, 16 PCs —

Evaluated Samples

PGS Sample Set ID
(PSS) 		Phenotype Definitions and Methods Participant Follow-up Time Sample Numbers Age of Study Participants Sample Ancestry Additional Ancestry Description Cohort(s) Additional Sample/Cohort Information
PSS009039 — — 3,448 individuals — African unspecified Nigeria (West Africa) UKB —
PSS008593 — — 1,011 individuals — Greater Middle Eastern (Middle Eastern, North African or Persian) Iran (Middle East) UKB —
PSS009265 — — 3,654 individuals — European Poland (NE Europe) UKB —
PSS008819 — — 6,027 individuals — European Italy (South Europe) UKB —
PSS008371 — — 5,655 individuals — South Asian India (South Asia) UKB —
PSS009491 — — 18,616 individuals — European UK (+ Ireland) UKB —
PSS008147 — — 1,576 individuals — East Asian China (East Asia) UKB —
PSS007935 — — 2,178 individuals — African American or Afro-Caribbean Carribean UKB —