Polygenic Score (PGS) ID: PGS002538

Predicted Trait
Reported Trait College education
Mapped Trait(s) educational attainment (EFO_0011015)
Released in PGS Catalog: June 9, 2022
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Score Details

Score Construction
PGS Name cov_EDU_COLLEGE.P+T.1e-06
Development Method
Name Pruning + Thresholding
Parameters p < 1e-06
Variants
Original Genome Build GRCh37
Number of Variants 1,136
Effect Weight Type BETA
PGS Source
PGS Catalog Publication (PGP) ID PGP000332
Citation (link to publication) Weissbrod O et al. Nat Genet (2022)
Ancestry Distribution
Source of Variant
Associations (GWAS)
European: 100%
334,353 individuals (100%)
PGS Evaluation
African: 25%
East Asian: 25%
European: 25%
South Asian: 25%
4 Sample Sets

Development Samples

Source of Variant Associations (GWAS)
Study Identifiers Sample Numbers Sample Ancestry Cohort(s)
334,353 individuals European UKB

Performance Metrics

Disclaimer: The performance metrics are displayed as reported by the source studies. It is important to note that metrics are not necessarily comparable with each other. For example, metrics depend on the sample characteristics (described by the PGS Catalog Sample Set [PSS] ID), phenotyping, and statistical modelling. Please refer to the source publication for additional guidance on performance.

PGS Performance
Metric ID (PPM)
PGS Sample Set ID
(PSS)
Performance Source Trait PGS Effect Sizes
(per SD change)
Classification Metrics Other Metrics Covariates Included in the Model PGS Performance:
Other Relevant Information
PPM013960 PSS009719|
African Ancestry|
6,277 individuals
PGP000332 |
Weissbrod O et al. Nat Genet (2022)
Reported Trait: College education Incremental R2 (full model vs. covariates alone): 0.001 age, sex, age‚age*sex, assessment center, genotyping array, 10 PCs
PPM014009 PSS009720|
East Asian Ancestry|
876 individuals
PGP000332 |
Weissbrod O et al. Nat Genet (2022)
Reported Trait: College education Incremental R2 (full model vs. covariates alone): 0.0003 age, sex, age‚age*sex, assessment center, genotyping array, 10 PCs
PPM014058 PSS009721|
European Ancestry|
42,914 individuals
PGP000332 |
Weissbrod O et al. Nat Genet (2022)
Reported Trait: College education Incremental R2 (full model vs. covariates alone): 0.0107 age, sex, age‚age*sex, assessment center, genotyping array, 10 PCs
PPM014107 PSS009722|
South Asian Ancestry|
7,658 individuals
PGP000332 |
Weissbrod O et al. Nat Genet (2022)
Reported Trait: College education Incremental R2 (full model vs. covariates alone): 0.0037 age, sex, age‚age*sex, assessment center, genotyping array, 10 PCs

Evaluated Samples

PGS Sample Set ID
(PSS)
Phenotype Definitions and Methods Participant Follow-up Time Sample Numbers Age of Study Participants Sample Ancestry Additional Ancestry Description Cohort(s) Additional Sample/Cohort Information
PSS009719 6,277 individuals African unspecified UKB
PSS009720 876 individuals East Asian UKB
PSS009721 42,914 individuals European Non-British European UKB
PSS009722 7,658 individuals South Asian UKB