Polygenic Score (PGS) ID: PGS002748

Predicted Trait
Reported Trait Height
Mapped Trait(s) body height (EFO_0004339)
Released in PGS Catalog: Sept. 8, 2022
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Score Details

Score Construction
PGS Name PRS_251
Development Method
Name Genome-wide significant SNPs
Parameters p<5E-05, r2=0.0712
Variants
Original Genome Build GRCh38
Number of Variants 251
Effect Weight Type beta
PGS Source
PGS Catalog Publication (PGP) ID PGP000361
Citation (link to publication) Chiou JS et al. BMC Med (2022)
Ancestry Distribution
Source of Variant
Associations (GWAS)
East Asian: 100%
67,452 individuals (100%)
PGS Evaluation
East Asian: 100%
1 Sample Sets

Development Samples

Source of Variant Associations (GWAS)
Study Identifiers Sample Numbers Sample Ancestry Cohort(s)
Europe PMC: 35831902
67,452 individuals East Asian
(Han Chinese)
Taiwan

Performance Metrics

Disclaimer: The performance metrics are displayed as reported by the source studies. It is important to note that metrics are not necessarily comparable with each other. For example, metrics depend on the sample characteristics (described by the PGS Catalog Sample Set [PSS] ID), phenotyping, and statistical modelling. Please refer to the source publication for additional guidance on performance.

PGS Performance
Metric ID (PPM)
PGS Sample Set ID
(PSS)
Performance Source Trait PGS Effect Sizes
(per SD change)
Classification Metrics Other Metrics Covariates Included in the Model PGS Performance:
Other Relevant Information
PPM014930 PSS009934|
East Asian Ancestry|
28,909 individuals
PGP000361 |
Chiou JS et al. BMC Med (2022)
Reported Trait: Height (female) β: 0.274
PPM014931 PSS009934|
East Asian Ancestry|
28,909 individuals
PGP000361 |
Chiou JS et al. BMC Med (2022)
Reported Trait: Body weight β: 1.218 [1.141, 1.296]
PPM014932 PSS009934|
East Asian Ancestry|
28,909 individuals
PGP000361 |
Chiou JS et al. BMC Med (2022)
Reported Trait: Waist circumference β: 0.446 [0.375, 0.517]
PPM014933 PSS009934|
East Asian Ancestry|
28,909 individuals
PGP000361 |
Chiou JS et al. BMC Med (2022)
Reported Trait: Hip circumference β: 0.601 [0.549, 0.652]
PPM014934 PSS009934|
East Asian Ancestry|
28,909 individuals
PGP000361 |
Chiou JS et al. BMC Med (2022)
Reported Trait: Body mass index β: -0.084 [-0.111, -0.056]
PPM014935 PSS009934|
East Asian Ancestry|
28,909 individuals
PGP000361 |
Chiou JS et al. BMC Med (2022)
Reported Trait: Waist‐hip ratio β: -0.001 [-0.001, 0.0]
PPM014936 PSS009934|
East Asian Ancestry|
28,909 individuals
PGP000361 |
Chiou JS et al. BMC Med (2022)
Reported Trait: Body fat β: -0.14 [-0.186, -0.095]
PPM014937 PSS009934|
East Asian Ancestry|
28,909 individuals
PGP000361 |
Chiou JS et al. BMC Med (2022)
Reported Trait: Total cholesterol β: -0.587 [-0.853, -0.321]
PPM014938 PSS009934|
East Asian Ancestry|
28,909 individuals
PGP000361 |
Chiou JS et al. BMC Med (2022)
Reported Trait: Low‐density lipoprotein cholesterol β: -0.629 [-0.867, -0.391]
PPM014929 PSS009934|
East Asian Ancestry|
28,909 individuals
PGP000361 |
Chiou JS et al. BMC Med (2022)
Reported Trait: Height (male) β: 0.257

Evaluated Samples

PGS Sample Set ID
(PSS)
Phenotype Definitions and Methods Participant Follow-up Time Sample Numbers Age of Study Participants Sample Ancestry Additional Ancestry Description Cohort(s) Additional Sample/Cohort Information
PSS009934 28,909 individuals,
38.0 % Male samples
East Asian
(Han Chinese)
Taiwan