Polygenic Score (PGS) ID: PGS002806

Predicted Trait
Reported Trait Gestational duration
Mapped Trait(s) gestational age (EFO_0005112)
Released in PGS Catalog: April 12, 2023
Download Score FTP directory
Terms and Licenses
PGS obtained from the Catalog should be cited appropriately, and used in accordance with any licensing restrictions set by the authors. See EBI Terms of Use (https://www.ebi.ac.uk/about/terms-of-use/) for additional details.

Score Details

Score Construction
PGS Name gesta_duration
Development Method
Name LDpred2
Parameters proportion of causal SNPs = 0.0032; heritability = 0.04; no sparse effect size estimates
Variants
Original Genome Build GRCh37
Number of Variants 1,120,085
Effect Weight Type beta
PGS Source
PGS Catalog Publication (PGP) ID PGP000383
Citation (link to publication) Solé-Navais P et al. Nat Genet (2023)
Ancestry Distribution
Source of Variant
Associations (GWAS)
European: 100%
129,594 individuals (100%)
Score Development/Training
European: 100%
15,768 individuals (100%)
PGS Evaluation
European: 100%
1 Sample Sets

Development Samples

Source of Variant Associations (GWAS)
Study Identifiers Sample Numbers Sample Ancestry Cohort(s)
— 129,594 individuals,
0.0 % Male samples
 European NR
Score Development/Training
Study Identifiers Sample Numbers Sample Ancestry Cohort(s) Phenotype Definitions & Methods Age of Study Participants Participant Follow-up Time Additional Ancestry Description Additional Sample/Cohort Information
— 15,768 individuals,
0.0 % Male samples
 European
(Northern-European)		 MOBA gestational duration (days) for spontaneous deliveries — — — —

Performance Metrics

Disclaimer: The performance metrics are displayed as reported by the source studies. It is important to note that metrics are not necessarily comparable with each other. For example, metrics depend on the sample characteristics (described by the PGS Catalog Sample Set [PSS] ID), phenotyping, and statistical modelling. Please refer to the source publication for additional guidance on performance.

PGS Performance
Metric ID (PPM) 		PGS Sample Set ID
(PSS) 		Performance Source Trait PGS Effect Sizes
(per SD change) 		Classification Metrics Other Metrics Covariates Included in the Model PGS Performance:
Other Relevant Information
PPM015537 PSS009979|
European Ancestry|
3,942 individuals
 PGP000383 |
Solé-Navais P et al. Nat Genet (2023)
 Reported Trait: Gestational duration β: 1.07 — R²: 0.013
Incremental R²: 0.012		 PC1-6, batch —

Evaluated Samples

PGS Sample Set ID
(PSS) 		Phenotype Definitions and Methods Participant Follow-up Time Sample Numbers Age of Study Participants Sample Ancestry Additional Ancestry Description Cohort(s) Additional Sample/Cohort Information
PSS009979 gestational duration (days) for spontaneous deliveries — 3,942 individuals,
0.0 % Male samples
 — European
(Northern-European)		 — MOBA —