Polygenic Score (PGS) ID: PGS003558

Predicted Trait
Reported Trait Hair/balding pattern
Mapped Trait(s) balding measurement (EFO_0007825)
Released in PGS Catalog: April 12, 2023
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Terms and Licenses
PGS obtained from the Catalog should be cited appropriately, and used in accordance with any licensing restrictions set by the authors. See EBI Terms of Use (https://www.ebi.ac.uk/about/terms-of-use/) for additional details.

Score Details

Score Construction
PGS Name cont-decay-M_less_hair
Development Method
Name LDpred2-auto
Parameters vec_p_init = seq_log(1e-4, 0.9, length.out = 10), burn_in = 100, num_iter = 500, report_step = 5
Variants
Original Genome Build GRCh37
Number of Variants 979,739
Effect Weight Type beta
PGS Source
PGS Catalog Publication (PGP) ID PGP000457
Citation (link to publication) Ding Y et al. bioRxiv (2022) Preprint
Ancestry Distribution
Score Development/Training
European: 100%
170,162 individuals (100%)
PGS Evaluation
European: 44.4%
African: 22.2%
East Asian: 11.1%
Greater Middle Eastern: 11.1%
South Asian: 11.1%
9 Sample Sets

Development Samples

Score Development/Training
Study Identifiers Sample Numbers Sample Ancestry Cohort(s) Phenotype Definitions & Methods Age of Study Participants Participant Follow-up Time Additional Ancestry Description Additional Sample/Cohort Information
170,162 individuals,
1.0 % Male samples
European UKB Mean = 57.1 years
Sd = 8.1 years
white British

Performance Metrics

Disclaimer: The performance metrics are displayed as reported by the source studies. It is important to note that metrics are not necessarily comparable with each other. For example, metrics depend on the sample characteristics (described by the PGS Catalog Sample Set [PSS] ID), phenotyping, and statistical modelling. Please refer to the source publication for additional guidance on performance.

PGS Performance
Metric ID (PPM)
PGS Sample Set ID
(PSS)
Performance Source Trait PGS Effect Sizes
(per SD change)
Classification Metrics Other Metrics Covariates Included in the Model PGS Performance:
Other Relevant Information
PPM017906 PSS010504|
South Asian Ancestry|
3,222 individuals
PGP000457 |
Ding Y et al. bioRxiv (2022)
|Pre
Reported Trait: Hair/balding pattern partial-R2: 0.13 sex, age, deprivation index, PC1-16
PPM017486 PSS010924|
European Ancestry|
9,180 individuals
PGP000457 |
Ding Y et al. bioRxiv (2022)
|Pre
Reported Trait: Hair/balding pattern partial-R2: 0.23 sex, age, deprivation index, PC1-16
PPM017570 PSS010840|
European Ancestry|
1,538 individuals
PGP000457 |
Ding Y et al. bioRxiv (2022)
|Pre
Reported Trait: Hair/balding pattern partial-R2: 0.23 sex, age, deprivation index, PC1-16
PPM017654 PSS010672|
European Ancestry|
2,874 individuals
PGP000457 |
Ding Y et al. bioRxiv (2022)
|Pre
Reported Trait: Hair/balding pattern partial-R2: 0.21 sex, age, deprivation index, PC1-16
PPM017738 PSS010588|
Greater Middle Eastern Ancestry|
669 individuals
PGP000457 |
Ding Y et al. bioRxiv (2022)
|Pre
Reported Trait: Hair/balding pattern partial-R2: 0.16 sex, age, deprivation index, PC1-16
PPM017822 PSS010252|
European Ancestry|
1,045 individuals
PGP000457 |
Ding Y et al. bioRxiv (2022)
|Pre
Reported Trait: Hair/balding pattern partial-R2: 0.19 sex, age, deprivation index, PC1-16
PPM017990 PSS010420|
East Asian Ancestry|
574 individuals
PGP000457 |
Ding Y et al. bioRxiv (2022)
|Pre
Reported Trait: Hair/balding pattern partial-R2: 0.08 sex, age, deprivation index, PC1-16
PPM018074 PSS010336|
African Ancestry|
838 individuals
PGP000457 |
Ding Y et al. bioRxiv (2022)
|Pre
Reported Trait: Hair/balding pattern partial-R2: 0.09 sex, age, deprivation index, PC1-16
PPM018158 PSS010756|
African Ancestry|
1,707 individuals
PGP000457 |
Ding Y et al. bioRxiv (2022)
|Pre
Reported Trait: Hair/balding pattern partial-R2: 0.04 sex, age, deprivation index, PC1-16

Evaluated Samples

PGS Sample Set ID
(PSS)
Phenotype Definitions and Methods Participant Follow-up Time Sample Numbers Age of Study Participants Sample Ancestry Additional Ancestry Description Cohort(s) Additional Sample/Cohort Information
PSS010336 838 individuals,
100.0 % Male samples
Mean = 52.8 years
Sd = 8.4 years
African American or Afro-Caribbean Caribbean UKB
PSS010756 1,707 individuals,
100.0 % Male samples
Mean = 51.3 years
Sd = 8.1 years
African unspecified Nigerian UKB
PSS010504 3,222 individuals,
100.0 % Male samples
Mean = 53.6 years
Sd = 8.7 years
South Asian Indian UKB
PSS010924 9,180 individuals,
100.0 % Male samples
Mean = 57.1 years
Sd = 8.0 years
European white British UKB
PSS010252 1,045 individuals,
100.0 % Male samples
Mean = 58.4 years
Sd = 7.1 years
European Ashkenazi UKB
PSS010672 2,874 individuals,
100.0 % Male samples
Mean = 54.8 years
Sd = 8.5 years
European Italian UKB
PSS010420 574 individuals,
100.0 % Male samples
Mean = 52.3 years
Sd = 8.2 years
East Asian Chinese UKB
PSS010840 1,538 individuals,
100.0 % Male samples
Mean = 54.1 years
Sd = 7.4 years
European Polish UKB
PSS010588 669 individuals,
100.0 % Male samples
Mean = 51.9 years
Sd = 8.0 years
Greater Middle Eastern (Middle Eastern, North African or Persian) Iranian UKB