Predicted Trait | |
Reported Trait | eGFR |
Mapped Trait(s) | glomerular filtration rate (EFO_0005208) |
Score Construction | |
PGS Name | prscs.auto.GCST008059.eGFR |
Development Method | |
Name | PRS-CS-auto |
Parameters | phi:auto |
Variants | |
Original Genome Build | GRCh38 |
Number of Variants | 1,109,217 |
Effect Weight Type | beta |
PGS Source | |
PGS Catalog Publication (PGP) ID | PGP000517 |
Citation (link to publication) | Monti R et al. Am J Hum Genet (2024) |
Study Identifiers | Sample Numbers | Sample Ancestry | Cohort(s) |
---|---|---|---|
GWAS Catalog: GCST008059 Europe PMC: 31152163 |
567,460 individuals | European | NR |
Study Identifiers | Sample Numbers | Sample Ancestry | Cohort(s) | Phenotype Definitions & Methods | Age of Study Participants | Participant Follow-up Time | Additional Ancestry Description | Additional Sample/Cohort Information |
---|---|---|---|---|---|---|---|---|
— | 344,140 individuals | European | UKB | — | — | — | — | — |
PGS Performance Metric ID (PPM) |
PGS Sample Set ID (PSS) |
Performance Source | Trait |
PGS Effect Sizes (per SD change) |
Classification Metrics | Other Metrics | Covariates Included in the Model |
PGS Performance: Other Relevant Information |
---|---|---|---|---|---|---|---|---|
PPM019783 | PSS011251| South Asian Ancestry| 3,061 individuals |
PGP000517 | Monti R et al. Am J Hum Genet (2024) |
Reported Trait: estimated glomerular filtration rate | β: 0.21078 | — | — | 0 | beta = sd_trait/sd_pgs = pearson correlation |
PPM019785 | PSS011266| European Ancestry| 66,759 individuals |
PGP000517 | Monti R et al. Am J Hum Genet (2024) |
Reported Trait: estimated glomerular filtration rate | β: 0.21808 | — | — | 0 | beta = sd_trait/sd_pgs = pearson correlation |
PPM019787 | PSS011293| South Asian Ancestry| 8,855 individuals |
PGP000517 | Monti R et al. Am J Hum Genet (2024) |
Reported Trait: estimated glomerular filtration rate | β: 0.27584 | — | — | 0 | beta = sd_trait/sd_pgs = pearson correlation |
PPM019789 | PSS011280| European Ancestry| 86,034 individuals |
PGP000517 | Monti R et al. Am J Hum Genet (2024) |
Reported Trait: estimated glomerular filtration rate | β: 0.30818 | — | — | 0 | beta = sd_trait/sd_pgs = pearson correlation |
PGS Sample Set ID (PSS) |
Phenotype Definitions and Methods | Participant Follow-up Time | Sample Numbers | Age of Study Participants | Sample Ancestry | Additional Ancestry Description | Cohort(s) | Additional Sample/Cohort Information |
---|---|---|---|---|---|---|---|---|
PSS011280 | — | — | 86,034 individuals | — | European | — | UKB | — |
PSS011266 | — | — | 66,759 individuals | — | European | — | HUNT | — |
PSS011251 | — | — | 3,061 individuals | — | South Asian | — | G&H | — |
PSS011293 | — | — | 8,855 individuals | — | South Asian | — | UKB | — |