Polygenic Score (PGS) ID: PGS004474

Predicted Trait
Reported Trait K57 (Diverticular disease of intestine)
Mapped Trait(s) diverticular disease (EFO_0009959)
Released in PGS Catalog: March 18, 2024
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Score Details

Score Construction
PGS Name disease.K57.score
Development Method
Name LDpred2
Parameters LDpred2-infinitesimal model using HapMap3 variants
Original Genome Build GRCh37
Number of Variants 1,059,939
Effect Weight Type beta
PGS Source
PGS Catalog Publication (PGP) ID PGP000561
Citation (link to publication) Jung H et al. Commun Biol (2024)
Ancestry Distribution
Score Development/Training
European: 100%
174,489 individuals (100%)
PGS Evaluation
European: 100%
1 Sample Sets

Development Samples

Score Development/Training
Study Identifiers Sample Numbers Sample Ancestry Cohort(s) Phenotype Definitions & Methods Age of Study Participants Participant Follow-up Time Additional Ancestry Description Additional Sample/Cohort Information
174,489 individuals European UKB

Performance Metrics

Disclaimer: The performance metrics are displayed as reported by the source studies. It is important to note that metrics are not necessarily comparable with each other. For example, metrics depend on the sample characteristics (described by the PGS Catalog Sample Set [PSS] ID), phenotyping, and statistical modelling. Please refer to the source publication for additional guidance on performance.

PGS Performance
Metric ID (PPM)
PGS Sample Set ID
Performance Source Trait PGS Effect Sizes
(per SD change)
Classification Metrics Other Metrics Covariates Included in the Model PGS Performance:
Other Relevant Information
PPM020589 PSS011364|
European Ancestry|
56,192 individuals
PGP000561 |
Jung H et al. Commun Biol (2024)
Reported Trait: K57 (Diverticular disease of intestine) OR: 1.3125

Evaluated Samples

PGS Sample Set ID
Phenotype Definitions and Methods Participant Follow-up Time Sample Numbers Age of Study Participants Sample Ancestry Additional Ancestry Description Cohort(s) Additional Sample/Cohort Information
PSS011364 56,192 individuals European UKB