Polygenic Score (PGS) ID: PGS019578

Predicted Trait
Reported Trait Carbuncle and furuncle
Mapped Trait(s)
Released in PGS Catalog: July 29, 2026
Download Score FTP directory
Terms and Licenses
PGS obtained from the Catalog should be cited appropriately, and used in accordance with any licensing restrictions set by the authors. See EBI Terms of Use (https://www.ebi.ac.uk/about/terms-of-use/) for additional details.

Score Details

Score Construction
PGS Name TPMI_686.1_LDpred2
Development Method
Name LDpred2
Parameters NR
Variants
Original Genome Build GRCh38
Number of Variants 277,466
Effect Weight Type beta
PGS Source
PGS Catalog Publication (PGP) ID PGP000835
Citation (link to publication) Chen HH et al. Nature (2025)
Ancestry Distribution
Source of Variant
Associations (GWAS)
East Asian: 100%
310,449 individuals (100%)
Score Development/Training
East Asian: 100%
71,910 individuals (100%)
PGS Evaluation
East Asian: 100%
1 Sample Sets

Development Samples

Source of Variant Associations (GWAS)
Study Identifiers Sample Numbers Sample Ancestry Cohort(s)
—
[
  • 3,240 cases
  • , 307,209 controls
]
,
44.23 % Male samples
 East Asian
(Han Chinese)		 TPMI
Score Development/Training
Study Identifiers Sample Numbers Sample Ancestry Cohort(s) Phenotype Definitions & Methods Age of Study Participants Participant Follow-up Time Additional Ancestry Description Additional Sample/Cohort Information
—
[
  • 775 cases
  • , 71,135 controls
]
,
45.6 % Male samples
 East Asian
(Han Chinese)		 TPMI 680,H60.0, L02.02, L02.03, L02.12, L02.13, L02.22, L02.23, L02.32, L02.33, L02.42, L02.43, L02.52, L02.53, L02.62, L02.63, L02.821, L02.828, L02.831, L02.838, L02.92, L02.93, N61.0, N61.1 — — — —

Performance Metrics

Disclaimer: The performance metrics are displayed as reported by the source studies. It is important to note that metrics are not necessarily comparable with each other. For example, metrics depend on the sample characteristics (described by the PGS Catalog Sample Set [PSS] ID), phenotyping, and statistical modelling. Please refer to the source publication for additional guidance on performance.

PGS Performance
Metric ID (PPM) 		PGS Sample Set ID
(PSS) 		Performance Source Trait PGS Effect Sizes
(per SD change) 		Classification Metrics Other Metrics Covariates Included in the Model PGS Performance:
Other Relevant Information
PPM037760 PSS013479|
East Asian Ancestry|
18,024 individuals
 PGP000835 |
Chen HH et al. Nature (2025)
 Reported Trait: Carbuncle and furuncle — AUROC: 0.67893 R²: 0.02188 sex, age, array, PCs 1-10 —

Evaluated Samples

PGS Sample Set ID
(PSS) 		Phenotype Definitions and Methods Participant Follow-up Time Sample Numbers Age of Study Participants Sample Ancestry Additional Ancestry Description Cohort(s) Additional Sample/Cohort Information
PSS013479 680,H60.0, L02.02, L02.03, L02.12, L02.13, L02.22, L02.23, L02.32, L02.33, L02.42, L02.43, L02.52, L02.53, L02.62, L02.63, L02.821, L02.828, L02.831, L02.838, L02.92, L02.93, N61.0, N61.1 —
[
  • 199 cases
  • , 17,825 controls
]
,
45.72 % Male samples
 — East Asian
(Han Chinese)		 — TPMI —