Polygenic Score (PGS) ID: PGS019970

Predicted Trait
Reported Trait Kidney cancer
Mapped Trait(s) kidney cancer (MONDO_0002367)
Released in PGS Catalog: Oct. 23, 2026
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Score Details

Score Construction
PGS Name Kidney
Development Method
Name SDPR
Parameters NR
Variants
Original Genome Build GRCh37
Number of Variants 1,083,402
Effect Weight Type beta
PGS Source
PGS Catalog Publication (PGP) ID PGP000850
Citation (link to publication) Hu J et al. PLoS Genet (2026)
Ancestry Distribution
Source of Variant
Associations (GWAS)
European: 100%
382,675 individuals (100%)
PGS Evaluation
European: 100%
1 Sample Sets

Development Samples

Source of Variant Associations (GWAS)
Study Identifiers Sample Numbers Sample Ancestry Cohort(s)
Europe PMC: 36653562
[
  • 3,926 cases
  • , 378,749 controls
]
 European
(Finnish)		 FinnGen

Performance Metrics

Disclaimer: The performance metrics are displayed as reported by the source studies. It is important to note that metrics are not necessarily comparable with each other. For example, metrics depend on the sample characteristics (described by the PGS Catalog Sample Set [PSS] ID), phenotyping, and statistical modelling. Please refer to the source publication for additional guidance on performance.

PGS Performance
Metric ID (PPM) 		PGS Sample Set ID
(PSS) 		Performance Source Trait PGS Effect Sizes
(per SD change) 		Classification Metrics Other Metrics Covariates Included in the Model PGS Performance:
Other Relevant Information
PPM038176 PSS013864|
European Ancestry|
354,186 individuals
 PGP000850 |
Hu J et al. PLoS Genet (2026)
 Reported Trait: Kidney cancer OR: 1.22 [1.17, 1.27] AUROC: 0.56 [0.54, 0.57] — — —

Evaluated Samples

PGS Sample Set ID
(PSS) 		Phenotype Definitions and Methods Participant Follow-up Time Sample Numbers Age of Study Participants Sample Ancestry Additional Ancestry Description Cohort(s) Additional Sample/Cohort Information
PSS013864 — —
[
  • 2,717 cases
  • , 351,469 controls
]
 — European
(EUR)		 — UKB —